Publication Information

{'id': 'https://openalex.org/W2085610013', 'doi': 'https://doi.org/10.1677/joe.0.0630149', 'title': 'METABOLISM OF [7α-3H]DEHYDROEPIANDROSTERONE AND [4-14C]ANDROSTENEDIONE IN VITRO BY TESTICULAR TISSUE FROM ADULT AND PREPUBERTAL WISTAR RATS', 'display_name': 'METABOLISM OF [7α-3H]DEHYDROEPIANDROSTERONE AND [4-14C]ANDROSTENEDIONE IN VITRO BY TESTICULAR TISSUE FROM ADULT AND PREPUBERTAL WISTAR RATS', 'publication_year': 1974, 'publication_date': '1974-10-01', 'ids': {'openalex': 'https://openalex.org/W2085610013', 'doi': 'https://doi.org/10.1677/joe.0.0630149', 'mag': '2085610013', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4278507'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1677/joe.0.0630149', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S34842069', 'display_name': 'Journal of Endocrinology', 'issn_l': '0022-0795', 'issn': ['0022-0795', '1479-6805'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319937', 'host_organization_name': 'Bioscientifica', 'host_organization_lineage': ['https://openalex.org/P4310319937'], 'host_organization_lineage_names': ['Bioscientifica'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108452271', 'display_name': 'GWEN RICHARDS', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'GWEN RICHARDS', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5028349353', 'display_name': 'Alan Nevill', 'orcid': 'https://orcid.org/0000-0003-0506-3652'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A. MUNRO NEVILLE', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.50064, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 65, 'max': 69}, 'biblio': {'volume': '63', 'issue': '1', 'first_page': '149', 'last_page': '155'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11146', 'display_name': 'Hormonal and reproductive studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11146', 'display_name': 'Hormonal and reproductive studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11956', 'display_name': 'Sexual Differentiation and Disorders', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Hormonal Regulation and Hypertension', 'score': 0.9878, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2776683971', 'wikidata': 'https://www.wikidata.org/wiki/Q411064', 'display_name': 'Androstenedione', 'level': 4, 'score': 0.98627096}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.8916001}, {'id': 'https://openalex.org/C2776992908', 'wikidata': 'https://www.wikidata.org/wiki/Q408376', 'display_name': 'Dehydroepiandrosterone', 'level': 4, 'score': 0.8859627}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.8848609}, {'id': 'https://openalex.org/C2779279991', 'wikidata': 'https://www.wikidata.org/wiki/Q6058681', 'display_name': 'Testosterone (patch)', 'level': 2, 'score': 0.72539353}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.5690153}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.55583483}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.48397088}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35461205}, {'id': 'https://openalex.org/C2777911890', 'wikidata': 'https://www.wikidata.org/wiki/Q62614', 'display_name': 'Androgen', 'level': 3, 'score': 0.31830636}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.23767668}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.17808515}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.124586314}], 'mesh': [{'descriptor_ui': 'D000735', 'descriptor_name': 'Androstenedione', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003687', 'descriptor_name': 'Dehydroepiandrosterone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013737', 'descriptor_name': 'Testis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000731', 'descriptor_name': 'Androstanes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000731', 'descriptor_name': 'Androstanes', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D000734', 'descriptor_name': 'Androstenediols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000734', 'descriptor_name': 'Androstenediols', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D000735', 'descriptor_name': 'Androstenedione', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000735', 'descriptor_name': 'Androstenedione', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D000738', 'descriptor_name': 'Androsterone', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D000738', 'descriptor_name': 'Androsterone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002250', 'descriptor_name': 'Carbon Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003687', 'descriptor_name': 'Dehydroepiandrosterone', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D003687', 'descriptor_name': 'Dehydroepiandrosterone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006913', 'descriptor_name': 'Hydroxysteroid Dehydrogenases', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D006913', 'descriptor_name': 'Hydroxysteroid Dehydrogenases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007664', 'descriptor_name': 'Ketosteroids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007664', 'descriptor_name': 'Ketosteroids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013737', 'descriptor_name': 'Testis', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D013737', 'descriptor_name': 'Testis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013739', 'descriptor_name': 'Testosterone', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D013739', 'descriptor_name': 'Testosterone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014316', 'descriptor_name': 'Tritium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1677/joe.0.0630149', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S34842069', 'display_name': 'Journal of Endocrinology', 'issn_l': '0022-0795', 'issn': ['0022-0795', '1479-6805'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319937', 'host_organization_name': 'Bioscientifica', 'host_organization_lineage': ['https://openalex.org/P4310319937'], 'host_organization_lineage_names': ['Bioscientifica'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4278507', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W2488528691', 'https://openalex.org/W2411838213', 'https://openalex.org/W2411194255', 'https://openalex.org/W2087060366', 'https://openalex.org/W2085610013', 'https://openalex.org/W2061449132', 'https://openalex.org/W2055011046', 'https://openalex.org/W2021664657', 'https://openalex.org/W2007896025', 'https://openalex.org/W1993446998'], 'abstract_inverted_index': {'SUMMARY': [0], 'The': [1], 'metabolism': [2], 'of': [3, 28, 58], '[7α-': [4], '3': [5], 'H]dehydroepiandrosterone': [6], '(DHA)': [7], 'and': [8, 20, 69], '[4-': [9], '14': [10], 'C]': [11], 'androstenedione': [12, 70], 'in': [13, 17, 25, 50, 73], 'vitro': [14], 'was': [15, 48], 'investigated': [16], '30-day-old': [18], '(prepubertal)': [19], 'adult': [21, 52], 'rat': [22], 'testicular': [23], 'tissue': [24], 'the': [26, 43, 51, 56, 64], 'presence': [27], 'cyanoketosteroid,': [29], 'a': [30], '5-ene-3β-hydroxysteroid': [31], 'oxidoreductase': [32], 'inhibitor.': [33], 'Whereas': [34], 'both': [35], 'substrates': [36], 'were': [37], 'converted': [38], 'to': [39], '5α-reduced': [40, 59], 'steroids': [41, 60], 'by': [42, 63], 'prepubertal': [44, 65], 'testis,': [45], '4-ene-steroid-5α-reductase': [46], 'activity': [47], 'negligible': [49], 'gland.': [53], 'Cyanoketosteroid': [54], 'prevented': [55], 'formation': [57], 'from': [61], 'DHA': [62], 'testis': [66], 'indicating': [67], 'testosterone': [68], 'as': [71], 'intermediates': [72], 'their': [74], 'production.': [75]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2085610013', 'counts_by_year': [], 'updated_date': '2024-12-10T03:29:44.372529', 'created_date': '2016-06-24'}