Publication Information

{'id': 'https://openalex.org/W2085325650', 'doi': 'https://doi.org/10.4161/cc.9.19.13139', 'title': 'Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells', 'display_name': 'Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells', 'publication_year': 2010, 'publication_date': '2010-10-01', 'ids': {'openalex': 'https://openalex.org/W2085325650', 'doi': 'https://doi.org/10.4161/cc.9.19.13139', 'mag': '2085325650', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20935507', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3047752'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.9.19.13139', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13139?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13139?needAccess=true&role=button', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100425921', 'display_name': 'Meng Meng', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72816309', 'display_name': 'Drexel University', 'ror': 'https://ror.org/04bdffz58', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I72816309']}, {'id': 'https://openalex.org/I922845939', 'display_name': 'Philadelphia University', 'ror': 'https://ror.org/03zzmyz63', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I922845939']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Meng Meng', 'raw_affiliation_strings': ['Drexel University', 'Philadelphia, PA USA'], 'affiliations': [{'raw_affiliation_string': 'Drexel University', 'institution_ids': ['https://openalex.org/I72816309']}, {'raw_affiliation_string': 'Philadelphia, PA USA', 'institution_ids': ['https://openalex.org/I922845939']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046473456', 'display_name': 'Shuyang Chen', 'orcid': 'https://orcid.org/0000-0002-4760-4106'}, 'institutions': [{'id': 'https://openalex.org/I72816309', 'display_name': 'Drexel University', 'ror': 'https://ror.org/04bdffz58', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I72816309']}, {'id': 'https://openalex.org/I922845939', 'display_name': 'Philadelphia University', 'ror': 'https://ror.org/03zzmyz63', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I922845939']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shuyang Chen', 'raw_affiliation_strings': ['Drexel University', 'Philadelphia, PA USA'], 'affiliations': [{'raw_affiliation_string': 'Drexel University', 'institution_ids': ['https://openalex.org/I72816309']}, {'raw_affiliation_string': 'Philadelphia, PA USA', 'institution_ids': ['https://openalex.org/I922845939']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042861374', 'display_name': 'Taotao Lao', 'orcid': 'https://orcid.org/0000-0001-9207-4071'}, 'institutions': [{'id': 'https://openalex.org/I72816309', 'display_name': 'Drexel University', 'ror': 'https://ror.org/04bdffz58', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I72816309']}, {'id': 'https://openalex.org/I922845939', 'display_name': 'Philadelphia University', 'ror': 'https://ror.org/03zzmyz63', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I922845939']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Taotao Lao', 'raw_affiliation_strings': ['Drexel University', 'Philadelphia, PA USA'], 'affiliations': [{'raw_affiliation_string': 'Drexel University', 'institution_ids': ['https://openalex.org/I72816309']}, {'raw_affiliation_string': 'Philadelphia, PA USA', 'institution_ids': ['https://openalex.org/I922845939']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077187844', 'display_name': 'Dongming Liang', 'orcid': 'https://orcid.org/0000-0002-7077-5747'}, 'institutions': [{'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dongming Liang', 'raw_affiliation_strings': ['Thomas Jefferson University, Philadelphia, PA'], 'affiliations': [{'raw_affiliation_string': 'Thomas Jefferson University, Philadelphia, PA', 'institution_ids': ['https://openalex.org/I149251103']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5080798250', 'display_name': 'Nianli Sang', 'orcid': 'https://orcid.org/0000-0003-3405-7788'}, 'institutions': [{'id': 'https://openalex.org/I149251103', 'display_name': 'Thomas Jefferson University', 'ror': 'https://ror.org/00ysqcn41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I149251103']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Nianli Sang', 'raw_affiliation_strings': ['Thomas Jefferson University, Philadelphia, PA'], 'affiliations': [{'raw_affiliation_string': 'Thomas Jefferson University, Philadelphia, PA', 'institution_ids': ['https://openalex.org/I149251103']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5080798250'], 'corresponding_institution_ids': ['https://openalex.org/I149251103'], 'apc_list': None, 'apc_paid': None, 'fwci': 2.487, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 83, 'citation_normalized_percentile': {'value': 0.999873, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '9', 'issue': '19', 'first_page': '3921', 'last_page': '3932'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10631', 'display_name': 'Cancer, Hypoxia, and Metabolism', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10631', 'display_name': 'Cancer, Hypoxia, and Metabolism', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12763', 'display_name': 'ATP Synthase and ATPases Research', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/glutaminolysis', 'display_name': 'Glutaminolysis', 'score': 0.9981419}, {'id': 'https://openalex.org/keywords/warburg-effect', 'display_name': 'Warburg Effect', 'score': 0.7571908}, {'id': 'https://openalex.org/keywords/hela', 'display_name': 'HeLa', 'score': 0.4660695}], 'concepts': [{'id': 'https://openalex.org/C2778160063', 'wikidata': 'https://www.wikidata.org/wiki/Q1532402', 'display_name': 'Glutaminolysis', 'level': 4, 'score': 0.9981419}, {'id': 'https://openalex.org/C109156525', 'wikidata': 'https://www.wikidata.org/wiki/Q56770304', 'display_name': 'Warburg effect', 'level': 4, 'score': 0.7571908}, {'id': 'https://openalex.org/C2779349466', 'wikidata': 'https://www.wikidata.org/wiki/Q181619', 'display_name': 'Glutamine', 'level': 3, 'score': 0.70738}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.65897214}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5846816}, {'id': 'https://openalex.org/C2777366897', 'wikidata': 'https://www.wikidata.org/wiki/Q847482', 'display_name': 'HeLa', 'level': 3, 'score': 0.4660695}, {'id': 'https://openalex.org/C1008401', 'wikidata': 'https://www.wikidata.org/wiki/Q184681', 'display_name': 'Anabolism', 'level': 2, 'score': 0.44949695}, {'id': 'https://openalex.org/C34905852', 'wikidata': 'https://www.wikidata.org/wiki/Q3943646', 'display_name': 'Stable isotope labeling by amino acids in cell culture', 'level': 4, 'score': 0.42981613}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3447383}, {'id': 'https://openalex.org/C20251656', 'wikidata': 'https://www.wikidata.org/wiki/Q162643', 'display_name': 'Glycolysis', 'level': 3, 'score': 0.32930642}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.30057693}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.2670446}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.1575293}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C46111723', 'wikidata': 'https://www.wikidata.org/wiki/Q471857', 'display_name': 'Proteomics', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005973', 'descriptor_name': 'Glutamine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008660', 'descriptor_name': 'Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009584', 'descriptor_name': 'Nitrogen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000409', 'descriptor_name': 'Alanine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000409', 'descriptor_name': 'Alanine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000641', 'descriptor_name': 'Ammonia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000641', 'descriptor_name': 'Ammonia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001224', 'descriptor_name': 'Aspartic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001224', 'descriptor_name': 'Aspartic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005973', 'descriptor_name': 'Glutamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007656', 'descriptor_name': 'Ketoglutaric Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007656', 'descriptor_name': 'Ketoglutaric Acids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009584', 'descriptor_name': 'Nitrogen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009696', 'descriptor_name': 'Nucleic Acids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D009696', 'descriptor_name': 'Nucleic Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013312', 'descriptor_name': 'Stress, Physiological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.9.19.13139', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13139?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3047752', 'pdf_url': 'https://europepmc.org/articles/pmc3047752?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047752', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20935507', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cc.9.19.13139', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13139?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S86011449', 'display_name': 'Cell Cycle', 'issn_l': '1551-4005', 'issn': ['1551-4005', '1538-4101'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1483212110', 'https://openalex.org/W1519324559', 'https://openalex.org/W1603094431', 'https://openalex.org/W1605454764', 'https://openalex.org/W1716126754', 'https://openalex.org/W1939960105', 'https://openalex.org/W1966094526', 'https://openalex.org/W1968068668', 'https://openalex.org/W1970345057', 'https://openalex.org/W1980881456', 'https://openalex.org/W1995490493', 'https://openalex.org/W1996365670', 'https://openalex.org/W2008081350', 'https://openalex.org/W2016105349', 'https://openalex.org/W2019465043', 'https://openalex.org/W2026936692', 'https://openalex.org/W2027705428', 'https://openalex.org/W2028115664', 'https://openalex.org/W2029591511', 'https://openalex.org/W2031795384', 'https://openalex.org/W2042593427', 'https://openalex.org/W2048216460', 'https://openalex.org/W2050140657', 'https://openalex.org/W2055255976', 'https://openalex.org/W2057199368', 'https://openalex.org/W2059747280', 'https://openalex.org/W2064443971', 'https://openalex.org/W2066379425', 'https://openalex.org/W2068335084', 'https://openalex.org/W2070371419', 'https://openalex.org/W2072451938', 'https://openalex.org/W2074873270', 'https://openalex.org/W2076835106', 'https://openalex.org/W2079606432', 'https://openalex.org/W2090880672', 'https://openalex.org/W2090927900', 'https://openalex.org/W2095377521', 'https://openalex.org/W2096015427', 'https://openalex.org/W2097259163', 'https://openalex.org/W2100260504', 'https://openalex.org/W2114853155', 'https://openalex.org/W2127675410', 'https://openalex.org/W2128200303', 'https://openalex.org/W2128744963', 'https://openalex.org/W2129532016', 'https://openalex.org/W2130021088', 'https://openalex.org/W2133573972', 'https://openalex.org/W2136749294', 'https://openalex.org/W2139301359', 'https://openalex.org/W2141817596', 'https://openalex.org/W2149901880', 'https://openalex.org/W2151365359', 'https://openalex.org/W4254119740'], 'related_works': ['https://openalex.org/W3102288871', 'https://openalex.org/W3030794675', 'https://openalex.org/W2914007480', 'https://openalex.org/W2159550690', 'https://openalex.org/W2135115897', 'https://openalex.org/W2131150552', 'https://openalex.org/W2111606497', 'https://openalex.org/W2040076847', 'https://openalex.org/W2028115664', 'https://openalex.org/W1998868825'], 'abstract_inverted_index': {'Glutaminolysis': [0], 'and': [1, 41, 52, 103, 129], 'Warburg': [2, 54, 168], 'effect': [3, 169], 'are': [4], 'the': [5, 53, 66, 70, 155, 167, 177], 'two': [6], 'most': [7], 'noticeable': [8], 'metabolic': [9, 119, 130, 173], 'features': [10], 'of': [11, 74, 105, 158], 'tumor': [12, 30], 'cells': [13, 31], 'whereas': [14], 'their': [15], 'biological': [16, 72], 'significance': [17], 'in': [18, 88, 107, 134, 151, 160], 'cell': [19, 86], 'proliferation': [20, 87, 104], 'remains': [21], 'elusive.': [22], 'A': [23], 'widely': [24], 'accepted': [25], 'current': [26], 'hypothesis': [27], 'is': [28, 96, 154], 'that': [29, 62, 94, 113, 142, 166], 'use': [32], 'glutamine': [33], 'as': [34, 147], 'a': [35, 100, 148, 172], 'preferred': [36], 'carbon': [37, 67, 118], 'source': [38, 115], 'for': [39, 76, 145], 'energy': [40], 'reducing': [42], 'power,': [43], 'which': [44], 'has': [45], 'been': [46], 'used': [47], 'to': [48, 60, 98, 176], 'explain': [49], 'both': [50], 'glutaminolysis': [51, 75, 159], 'effect.': [55], 'Here': [56], 'we': [57, 92, 137], 'provide': [58], 'evidence': [59], 'show': [61, 80, 93], 'supplying': [63, 83], 'nitrogen,': [64], 'not': [65], 'skeleton,': [68], 'underlies': [69], 'major': [71], 'importance': [73], 'proliferating': [77, 161], 'cells.': [78, 162], 'We': [79, 110], 'alternative': [81, 140], 'nitrogen': [82, 114, 152, 178], 'mechanisms': [84], 'rescue': [85], 'glutamine-free': [89, 108], 'media.': [90, 109], 'Particularly,': [91], 'ammonia': [95], 'sufficient': [97], 'maintain': [99], 'long-term': [101], 'survival': [102], 'Hep3B': [106], 'also': [111], 'observed': [112], 'restriction': [116], 'repressed': [117], 'pathways': [120, 131], 'including': [121], 'glucose': [122], 'utilization.': [123], 'Based': [124], 'on': [125], 'these': [126], 'new': [127], 'observations': [128], 'well': [132], 'established': [133], 'published': [135], 'literature,': [136], 'propose': [138], 'an': [139], 'model': [141, 164], 'cellular': [143], 'demand': [144], 'glutamate': [146], 'key': [149], 'molecule': [150], 'anabolism': [153], 'driving': [156], 'force': [157], 'Our': [163], 'suggests': [165], 'may': [170], 'be': [171], 'consequence': [174], 'secondary': [175], 'anabolism.': [179]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2085325650', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-24T14:35:06.214301', 'created_date': '2016-06-24'}