Publication Information

{'id': 'https://openalex.org/W2084402753', 'doi': 'https://doi.org/10.1159/000026566', 'title': 'Chronic Oral Haloperidol and Clozapine in Rats: A Behavioral Evaluation', 'display_name': 'Chronic Oral Haloperidol and Clozapine in Rats: A Behavioral Evaluation', 'publication_year': 1999, 'publication_date': '1999-01-01', 'ids': {'openalex': 'https://openalex.org/W2084402753', 'doi': 'https://doi.org/10.1159/000026566', 'mag': '2084402753', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10072665'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000026566', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S147539111', 'display_name': 'Neuropsychobiology', 'issn_l': '0302-282X', 'issn': ['0302-282X', '1423-0224'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087349845', 'display_name': 'Ulrich Schmitt', 'orcid': 'https://orcid.org/0000-0002-5657-4527'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ulrich Schmitt', 'raw_affiliation_strings': ['Psychiatry and'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034682876', 'display_name': 'Norbert Dahmen', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Norbert Dahmen', 'raw_affiliation_strings': ['Psychiatry and'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111622301', 'display_name': 'Viola Fischer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Viola Fischer', 'raw_affiliation_strings': ['Psychiatry and'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023818933', 'display_name': 'Harald Weigmann', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Harald Weigmann', 'raw_affiliation_strings': ['Psychiatry and'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113613319', 'display_name': 'Marie Luise Rao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135140700', 'display_name': 'University of Bonn', 'ror': 'https://ror.org/041nas322', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I135140700']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Marie Luise Rao', 'raw_affiliation_strings': ['Department of Psychiatry, University of Bonn, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Psychiatry, University of Bonn, Germany', 'institution_ids': ['https://openalex.org/I135140700']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073888945', 'display_name': 'Stefan Reuss', 'orcid': 'https://orcid.org/0000-0003-1064-5067'}, 'institutions': [{'id': 'https://openalex.org/I197323543', 'display_name': 'Johannes Gutenberg University Mainz', 'ror': 'https://ror.org/023b0x485', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I197323543']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stefan Reuss', 'raw_affiliation_strings': ['Anatomy, University of Mainz,'], 'affiliations': [{'raw_affiliation_string': 'Anatomy, University of Mainz,', 'institution_ids': ['https://openalex.org/I197323543']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007740742', 'display_name': 'Christoph Hiemke', 'orcid': 'https://orcid.org/0000-0003-2820-8738'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Christoph Hiemke', 'raw_affiliation_strings': ['Psychiatry and'], 'affiliations': [{'raw_affiliation_string': 'Psychiatry and', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.742, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.793309, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '39', 'issue': '2', 'first_page': '86', 'last_page': '91'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10023', 'display_name': 'Schizophrenia research and treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9856, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9806, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780948584', 'wikidata': 'https://www.wikidata.org/wiki/Q251347', 'display_name': 'Haloperidol', 'level': 3, 'score': 0.9769112}, {'id': 'https://openalex.org/C2780864610', 'wikidata': 'https://www.wikidata.org/wiki/Q221361', 'display_name': 'Clozapine', 'level': 3, 'score': 0.95987004}, {'id': 'https://openalex.org/C50610925', 'wikidata': 'https://www.wikidata.org/wiki/Q1136816', 'display_name': 'Habituation', 'level': 2, 'score': 0.74321675}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.59642076}, {'id': 'https://openalex.org/C2779085643', 'wikidata': 'https://www.wikidata.org/wiki/Q7096029', 'display_name': 'Open field', 'level': 2, 'score': 0.52416134}, {'id': 'https://openalex.org/C2777056448', 'wikidata': 'https://www.wikidata.org/wiki/Q285166', 'display_name': 'Oral administration', 'level': 2, 'score': 0.50464857}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.45307115}, {'id': 'https://openalex.org/C2780035454', 'wikidata': 'https://www.wikidata.org/wiki/Q8386', 'display_name': 'Drug', 'level': 2, 'score': 0.45132533}, {'id': 'https://openalex.org/C2776412080', 'wikidata': 'https://www.wikidata.org/wiki/Q7431605', 'display_name': 'Schizophrenia (object-oriented programming)', 'level': 2, 'score': 0.38282916}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.35626444}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3377515}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.3086406}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.27169645}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.123749375}, {'id': 'https://openalex.org/C548259974', 'wikidata': 'https://www.wikidata.org/wiki/Q569965', 'display_name': 'Audiology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001522', 'descriptor_name': 'Behavior, Animal', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D003024', 'descriptor_name': 'Clozapine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000704', 'descriptor_name': 'Analysis of Variance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014150', 'descriptor_name': 'Antipsychotic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D001522', 'descriptor_name': 'Behavior, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003024', 'descriptor_name': 'Clozapine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D003024', 'descriptor_name': 'Clozapine', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D003024', 'descriptor_name': 'Clozapine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004409', 'descriptor_name': 'Dyskinesia, Drug-Induced', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005106', 'descriptor_name': 'Exploratory Behavior', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005106', 'descriptor_name': 'Exploratory Behavior', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006185', 'descriptor_name': 'Habituation, Psychophysiologic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006185', 'descriptor_name': 'Habituation, Psychophysiologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006220', 'descriptor_name': 'Haloperidol', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008124', 'descriptor_name': 'Locomotion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008124', 'descriptor_name': 'Locomotion', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015430', 'descriptor_name': 'Weight Gain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015430', 'descriptor_name': 'Weight Gain', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000026566', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S147539111', 'display_name': 'Neuropsychobiology', 'issn_l': '0302-282X', 'issn': ['0302-282X', '1423-0224'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10072665', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6', 'score': 0.47}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 30, 'referenced_works': ['https://openalex.org/W115808356', 'https://openalex.org/W1668835600', 'https://openalex.org/W180775370', 'https://openalex.org/W1965470610', 'https://openalex.org/W1972791221', 'https://openalex.org/W1980127085', 'https://openalex.org/W1988211543', 'https://openalex.org/W2011537858', 'https://openalex.org/W2015091215', 'https://openalex.org/W2020871709', 'https://openalex.org/W2026615999', 'https://openalex.org/W2028692262', 'https://openalex.org/W2033894560', 'https://openalex.org/W2036066867', 'https://openalex.org/W2039808342', 'https://openalex.org/W2042259014', 'https://openalex.org/W2044213114', 'https://openalex.org/W2046346017', 'https://openalex.org/W2057971428', 'https://openalex.org/W2059230444', 'https://openalex.org/W2065748094', 'https://openalex.org/W2077478955', 'https://openalex.org/W2087419203', 'https://openalex.org/W2095148556', 'https://openalex.org/W2100344023', 'https://openalex.org/W2154308586', 'https://openalex.org/W2334751179', 'https://openalex.org/W2419900567', 'https://openalex.org/W2573827028', 'https://openalex.org/W433188473'], 'related_works': ['https://openalex.org/W4252184856', 'https://openalex.org/W2808137188', 'https://openalex.org/W2802830869', 'https://openalex.org/W2252546158', 'https://openalex.org/W2092139372', 'https://openalex.org/W2084402753', 'https://openalex.org/W2067578791', 'https://openalex.org/W1988346923', 'https://openalex.org/W1911283308', 'https://openalex.org/W1504727944'], 'abstract_inverted_index': {'The': [0], 'present': [1], 'study': [2], 'evaluated': [3], 'chronic': [4, 115], 'oral': [5, 102], 'treatment': [6, 116], 'of': [7, 52, 65, 75, 113], 'rats': [8], 'with': [9], 'haloperidol': [10, 41, 56], 'or': [11, 42], 'clozapine.': [12], 'Drugs': [13], 'were': [14], 'given': [15], 'in': [16, 32, 93, 129], 'the': [17, 63, 66, 73, 83, 106], 'drinking': [18, 107], 'water': [19, 108], 'for': [20, 55, 60], 'a': [21, 30, 90, 110], '23-day': [22], 'period': [23], '.': [24], 'Rat': [25], 'behavior': [26], 'was': [27], 'analyzed': [28], 'once': [29], 'week': [31], 'an': [33], 'open': [34], 'field.': [35], 'Rats': [36], 'ingested': [37], 'either': [38], '1.7': [39], 'mg/kg': [40, 44], '40': [43], 'clozapine': [45, 61], 'daily.': [46], 'Blood': [47], 'serum': [48], 'analysis': [49], 'revealed': [50], 'concentrations': [51], '6': [53], 'ng/ml': [54, 59], 'and': [57], '22': [58], 'at': [62], 'end': [64], 'treatment.': [67, 76], 'Haloperidol': [68], 'decreased': [69], 'overall': [70], 'activity': [71], 'from': [72], 'onset': [74], 'Clozapine': [77], 'showed': [78, 89], 'similar': [79], 'effects': [80, 128], 'only': [81], 'on': [82], 'last': [84], 'test': [85], 'day.': [86], 'Control': [87], 'animals': [88], 'slight': [91], 'habituation': [92], 'exploration-related': [94], 'parameters.': [95], 'In': [96], 'conclusion,': [97], 'these': [98], 'results': [99], 'indicate': [100], 'that': [101, 117], 'drug': [103, 122], 'administration': [104], 'through': [105], 'is': [109], 'suitable': [111], 'mode': [112], 'noninvasive': [114], 'led': [118], 'to': [119, 124], 'sufficiently': [120], 'high': [121], 'levels': [123], 'induce': [125], 'specific': [126], 'pharmacological': [127], 'rats.': [130]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2084402753', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-17T04:05:47.107805', 'created_date': '2016-06-24'}