Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2084235450', 'doi': 'https://doi.org/10.1002/sca.20154', 'title': 'Imaging and studying human topoisomerase I on mica surfaces in air and in liquid by atomic force microscopy', 'display_name': 'Imaging and studying human topoisomerase I on mica surfaces in air and in liquid by atomic force microscopy', 'publication_year': 2009, 'publication_date': '2009-07-01', 'ids': {'openalex': 'https://openalex.org/W2084235450', 'doi': 'https://doi.org/10.1002/sca.20154', 'mag': '2084235450', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19688808'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/sca.20154', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S51527640', 'display_name': 'Scanning', 'issn_l': '0161-0457', 'issn': ['0161-0457', '1932-8745'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100636196', 'display_name': 'Zhiguo Liu', 'orcid': 'https://orcid.org/0000-0003-4644-9578'}, 'institutions': [{'id': 'https://openalex.org/I47689461', 'display_name': 'Northeast Forestry University', 'ror': 'https://ror.org/02yxnh564', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I47689461']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhiguo Liu', 'raw_affiliation_strings': ['Key Laboratory of Forest Plant Ecology of Ministry of Education, Northeast Forestry University, Harbin, China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Forest Plant Ecology of Ministry of Education, Northeast Forestry University, Harbin, China.', 'institution_ids': ['https://openalex.org/I47689461']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070898194', 'display_name': 'Ronghua Meng', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ronghua Meng', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042138924', 'display_name': 'Yuangang Zu', 'orcid': 'https://orcid.org/0000-0002-3931-1872'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yuangang Zu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101433368', 'display_name': 'Qingyong Li', 'orcid': 'https://orcid.org/0000-0003-1492-3909'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Qingyong Li', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022160784', 'display_name': 'Liping Yao', 'orcid': 'https://orcid.org/0000-0001-6897-140X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Liping Yao', 'raw_affiliation_strings': [], 'affiliations': []}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1350, 'currency': 'USD', 'value_usd': 1350, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.556, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.667401, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '31', 'issue': '4', 'first_page': '160', 'last_page': '166'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11845', 'display_name': 'DNA Topoisomerases: Structure, Function, and Inhibition', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11845', 'display_name': 'DNA Topoisomerases: Structure, Function, and Inhibition', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12226', 'display_name': 'Neuroblastoma Research and Treatment', 'score': 0.9864, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11036', 'display_name': 'Pharmacokinetics of Antibiotics in Critically Ill Patients', 'score': 0.9828, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/continuous-infusion', 'display_name': 'Continuous Infusion', 'score': 0.426124}], 'concepts': [{'id': 'https://openalex.org/C2781038479', 'wikidata': 'https://www.wikidata.org/wiki/Q114675', 'display_name': 'Mica', 'level': 2, 'score': 0.99074626}, {'id': 'https://openalex.org/C102951782', 'wikidata': 'https://www.wikidata.org/wiki/Q49295', 'display_name': 'Atomic force microscopy', 'level': 2, 'score': 0.856609}, {'id': 'https://openalex.org/C7070889', 'wikidata': 'https://www.wikidata.org/wiki/Q902488', 'display_name': 'Monolayer', 'level': 2, 'score': 0.8344908}, {'id': 'https://openalex.org/C150394285', 'wikidata': 'https://www.wikidata.org/wiki/Q180254', 'display_name': 'Adsorption', 'level': 2, 'score': 0.6224096}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.52772725}, {'id': 'https://openalex.org/C147080431', 'wikidata': 'https://www.wikidata.org/wiki/Q1074953', 'display_name': 'Microscopy', 'level': 2, 'score': 0.509052}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.41109356}, {'id': 'https://openalex.org/C113196181', 'wikidata': 'https://www.wikidata.org/wiki/Q485223', 'display_name': 'Analytical Chemistry (journal)', 'level': 2, 'score': 0.3915875}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.38820755}, {'id': 'https://openalex.org/C8010536', 'wikidata': 'https://www.wikidata.org/wiki/Q160398', 'display_name': 'Crystallography', 'level': 1, 'score': 0.3319927}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.2123824}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.14874983}, {'id': 'https://openalex.org/C159985019', 'wikidata': 'https://www.wikidata.org/wiki/Q181790', 'display_name': 'Composite material', 'level': 1, 'score': 0.13511223}, {'id': 'https://openalex.org/C147789679', 'wikidata': 'https://www.wikidata.org/wiki/Q11372', 'display_name': 'Physical chemistry', 'level': 1, 'score': 0.072190255}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.06765926}], 'mesh': [{'descriptor_ui': 'D004264', 'descriptor_name': 'DNA Topoisomerases, Type I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018625', 'descriptor_name': 'Microscopy, Atomic Force', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000327', 'descriptor_name': 'Adsorption', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000388', 'descriptor_name': 'Air', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000538', 'descriptor_name': 'Aluminum Silicates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004264', 'descriptor_name': 'DNA Topoisomerases, Type I', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D004264', 'descriptor_name': 'DNA Topoisomerases, Type I', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018625', 'descriptor_name': 'Microscopy, Atomic Force', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014867', 'descriptor_name': 'Water', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/sca.20154', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S51527640', 'display_name': 'Scanning', 'issn_l': '0161-0457', 'issn': ['0161-0457', '1932-8745'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19688808', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1975873807', 'https://openalex.org/W1986153496', 'https://openalex.org/W1996572376', 'https://openalex.org/W1998631554', 'https://openalex.org/W2000519619', 'https://openalex.org/W2003038355', 'https://openalex.org/W2006424757', 'https://openalex.org/W2006758809', 'https://openalex.org/W2006853138', 'https://openalex.org/W2011733534', 'https://openalex.org/W2012968377', 'https://openalex.org/W2018807441', 'https://openalex.org/W2019037586', 'https://openalex.org/W2023574131', 'https://openalex.org/W2031733136', 'https://openalex.org/W2056269944', 'https://openalex.org/W2072546473', 'https://openalex.org/W2093225985', 'https://openalex.org/W2103489107', 'https://openalex.org/W2131188642', 'https://openalex.org/W2132600317', 'https://openalex.org/W2134909516', 'https://openalex.org/W2135635018', 'https://openalex.org/W2143540931', 'https://openalex.org/W2161241792', 'https://openalex.org/W2163851945'], 'related_works': ['https://openalex.org/W2918615328', 'https://openalex.org/W2611048337', 'https://openalex.org/W2349368527', 'https://openalex.org/W2271022063', 'https://openalex.org/W2084235450', 'https://openalex.org/W2073947304', 'https://openalex.org/W2020882885', 'https://openalex.org/W2007790245', 'https://openalex.org/W1989500502', 'https://openalex.org/W1967090135'], 'abstract_inverted_index': {'Abstract': [0], 'In': [1], 'this': [2], 'study,': [3], 'the': [4, 48, 92], 'topography': [5], 'of': [6, 31, 47, 75, 91], 'human': [7], 'topoisomerase': [8], 'I': [9, 33, 52, 69, 77, 96, 104, 112], '(TOPO': [10], 'I)': [11], 'on': [12, 34, 53, 78, 97, 114], 'mica': [13, 35, 54, 79, 98, 115], 'surfaces': [14, 55, 80, 99], 'in': [15, 18, 37, 62, 81], 'air': [16, 38], 'and': [17, 59, 118], 'liquid': [19, 63, 82], 'has': [20], 'been': [21], 'studied': [22], 'by': [23, 40, 64, 84], 'atomic': [24], 'force': [25], 'microscopy': [26], '(AFM).': [27], 'The': [28, 72, 109], 'average': [29, 73], 'height': [30, 74], 'TOPO': [32, 51, 68, 76, 95, 103, 111], 'surface': [36], 'measured': [39, 83], 'AFM': [41, 85], 'was': [42, 70, 86, 116], '2.59±0.32': [43], 'nm.': [44, 88], 'After': [45, 89], 'adsorption': [46, 90], '0.3': [49], 'U/µl': [50, 94], 'for': [56, 100], '2': [57], 'h,': [58, 102], 'then': [60], 'imaged': [61], 'AFM,': [65], 'well‐separated': [66], 'single': [67], 'observed.': [71], '2.93±0.42': [87], '4': [93], '1.5': [101], 'monolayer': [105, 113], 'can': [106], 'be': [107], 'formed.': [108], 'produced': [110], 'flat': [117], 'exhibited': [119], 'good': [120], 'stability.': [121], 'SCANNING': [122], '31:': [123], '160–166,': [124], '2009.': [125], '©': [126], '2009': [127], 'Wiley': [128], 'Periodicals,': [129], 'Inc.': [130]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2084235450', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-08-13T15:02:49.180404', 'created_date': '2016-06-24'}