Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2083907066', 'doi': 'https://doi.org/10.1016/s1470-2045(04)01494-9', 'title': 'Systematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer', 'display_name': 'Systematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer', 'publication_year': 2004, 'publication_date': '2004-06-01', 'ids': {'openalex': 'https://openalex.org/W2083907066', 'doi': 'https://doi.org/10.1016/s1470-2045(04)01494-9', 'mag': '2083907066', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15172358'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1470-2045(04)01494-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116900674', 'display_name': 'The Lancet Oncology', 'issn_l': '1470-2045', 'issn': ['1470-2045', '1474-5488'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015006267', 'display_name': 'Anna K. Nowak', 'orcid': 'https://orcid.org/0000-0002-9317-9526'}, 'institutions': [{'id': 'https://openalex.org/I42131985', 'display_name': 'National Health and Medical Research Council', 'ror': 'https://ror.org/011kf5r70', 'country_code': 'AU', 'type': 'government', 'lineage': ['https://openalex.org/I2801453606', 'https://openalex.org/I3149551504', 'https://openalex.org/I42131985']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'AK Nowak', 'raw_affiliation_strings': ['National Health and Medical Research Centre (NHMRC) Clinical Trials Centre'], 'affiliations': [{'raw_affiliation_string': 'National Health and Medical Research Centre (NHMRC) Clinical Trials Centre', 'institution_ids': ['https://openalex.org/I42131985']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031309734', 'display_name': 'N. Wilcken', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801862688', 'display_name': 'Cancer Institute of New South Wales', 'ror': 'https://ror.org/029a54f25', 'country_code': 'AU', 'type': 'other', 'lineage': ['https://openalex.org/I1311436738', 'https://openalex.org/I2801351115', 'https://openalex.org/I2801862688']}, {'id': 'https://openalex.org/I2803024705', 'display_name': 'Westmead Hospital', 'ror': 'https://ror.org/04gp5yv64', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2803024705']}, {'id': 'https://openalex.org/I129604602', 'display_name': 'University of Sydney', 'ror': 'https://ror.org/0384j8v12', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I129604602']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'NRC Wilcken', 'raw_affiliation_strings': ['Department of Medical Oncology, Westmead Hospital, and NSW Breast Cancer Institute at the University of Sydney, NSW, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Oncology, Westmead Hospital, and NSW Breast Cancer Institute at the University of Sydney, NSW, Australia', 'institution_ids': ['https://openalex.org/I2801862688', 'https://openalex.org/I2803024705', 'https://openalex.org/I129604602']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061757629', 'display_name': 'Martin R. Stockler', 'orcid': 'https://orcid.org/0000-0003-3793-8724'}, 'institutions': [{'id': 'https://openalex.org/I2800249840', 'display_name': 'Concord Repatriation General Hospital', 'ror': 'https://ror.org/04b0n4406', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800249840']}, {'id': 'https://openalex.org/I42131985', 'display_name': 'National Health and Medical Research Council', 'ror': 'https://ror.org/011kf5r70', 'country_code': 'AU', 'type': 'government', 'lineage': ['https://openalex.org/I2801453606', 'https://openalex.org/I3149551504', 'https://openalex.org/I42131985']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'MR Stockler', 'raw_affiliation_strings': ['National Health and Medical Research Centre (NHMRC) Clinical Trials Centre', 'Sydney Cancer Centre-Royal Prince Alfred and Concord Repatriation General Hospitals, Australia'], 'affiliations': [{'raw_affiliation_string': 'Sydney Cancer Centre-Royal Prince Alfred and Concord Repatriation General Hospitals, Australia', 'institution_ids': ['https://openalex.org/I2800249840']}, {'raw_affiliation_string': 'National Health and Medical Research Centre (NHMRC) Clinical Trials Centre', 'institution_ids': ['https://openalex.org/I42131985']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101480390', 'display_name': 'A. Hamilton', 'orcid': 'https://orcid.org/0000-0002-3135-4106'}, 'institutions': [{'id': 'https://openalex.org/I2800249840', 'display_name': 'Concord Repatriation General Hospital', 'ror': 'https://ror.org/04b0n4406', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800249840']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'A Hamilton', 'raw_affiliation_strings': ['Sydney Cancer Centre-Royal Prince Alfred and Concord Repatriation General Hospitals, Australia'], 'affiliations': [{'raw_affiliation_string': 'Sydney Cancer Centre-Royal Prince Alfred and Concord Repatriation General Hospitals, Australia', 'institution_ids': ['https://openalex.org/I2800249840']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5043048253', 'display_name': 'Davina Ghersi', 'orcid': 'https://orcid.org/0000-0002-9712-1604'}, 'institutions': [{'id': 'https://openalex.org/I42131985', 'display_name': 'National Health and Medical Research Council', 'ror': 'https://ror.org/011kf5r70', 'country_code': 'AU', 'type': 'government', 'lineage': ['https://openalex.org/I2801453606', 'https://openalex.org/I3149551504', 'https://openalex.org/I42131985']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'D Ghersi', 'raw_affiliation_strings': ['National Health and Medical Research Centre (NHMRC) Clinical Trials Centre'], 'affiliations': [{'raw_affiliation_string': 'National Health and Medical Research Centre (NHMRC) Clinical Trials Centre', 'institution_ids': ['https://openalex.org/I42131985']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6300, 'currency': 'USD', 'value_usd': 6300, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.7, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 112, 'citation_normalized_percentile': {'value': 0.998867, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '5', 'issue': '6', 'first_page': '372', 'last_page': '380'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11752', 'display_name': 'Chemotherapy-Induced Peripheral Neuropathy in Cancer Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11752', 'display_name': 'Chemotherapy-Induced Peripheral Neuropathy in Cancer Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10183', 'display_name': 'Molecular Research on Breast Cancer', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10755', 'display_name': 'HER2 Signaling in Breast Cancer Treatment', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/taxane', 'display_name': 'Taxane', 'score': 0.94983494}, {'id': 'https://openalex.org/keywords/neoadjuvant-therapy', 'display_name': 'Neoadjuvant Therapy', 'score': 0.574245}, {'id': 'https://openalex.org/keywords/breast-cancer', 'display_name': 'Breast Cancer', 'score': 0.526311}], 'concepts': [{'id': 'https://openalex.org/C2777511904', 'wikidata': 'https://www.wikidata.org/wiki/Q425227', 'display_name': 'Taxane', 'level': 4, 'score': 0.94983494}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9119971}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.8064592}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.7496865}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.7018207}, {'id': 'https://openalex.org/C2777863537', 'wikidata': 'https://www.wikidata.org/wiki/Q357896', 'display_name': 'Adjuvant', 'level': 2, 'score': 0.68621314}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.6412883}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.4575547}, {'id': 'https://openalex.org/C2778292576', 'wikidata': 'https://www.wikidata.org/wiki/Q6991934', 'display_name': 'Neoadjuvant therapy', 'level': 4, 'score': 0.4374339}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.42104125}], 'mesh': [{'descriptor_ui': 'D000971', 'descriptor_name': 'Antineoplastic Combined Chemotherapy Protocols', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D043823', 'descriptor_name': 'Taxoids', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000971', 'descriptor_name': 'Antineoplastic Combined Chemotherapy Protocols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D001943', 'descriptor_name': 'Breast Neoplasms', 'qualifier_ui': 'Q000601', 'qualifier_name': 'surgery', 'is_major_topic': False}, {'descriptor_ui': 'D017024', 'descriptor_name': 'Chemotherapy, Adjuvant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077143', 'descriptor_name': 'Docetaxel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007262', 'descriptor_name': 'Infusions, Intravenous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008408', 'descriptor_name': 'Mastectomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008408', 'descriptor_name': 'Mastectomy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020360', 'descriptor_name': 'Neoadjuvant Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009367', 'descriptor_name': 'Neoplasm Staging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017239', 'descriptor_name': 'Paclitaxel', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D017239', 'descriptor_name': 'Paclitaxel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017239', 'descriptor_name': 'Paclitaxel', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D016032', 'descriptor_name': 'Randomized Controlled Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043823', 'descriptor_name': 'Taxoids', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D043823', 'descriptor_name': 'Taxoids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s1470-2045(04)01494-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116900674', 'display_name': 'The Lancet Oncology', 'issn_l': '1470-2045', 'issn': ['1470-2045', '1474-5488'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15172358', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.86}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 13, 'referenced_works': ['https://openalex.org/W1924346446', 'https://openalex.org/W1948389446', 'https://openalex.org/W1975854376', 'https://openalex.org/W1993235281', 'https://openalex.org/W2014197113', 'https://openalex.org/W2075642745', 'https://openalex.org/W2101760255', 'https://openalex.org/W2127501098', 'https://openalex.org/W2135800076', 'https://openalex.org/W2138734774', 'https://openalex.org/W2141056749', 'https://openalex.org/W2162760540', 'https://openalex.org/W2244324403'], 'related_works': ['https://openalex.org/W4388328474', 'https://openalex.org/W4388111924', 'https://openalex.org/W4383058846', 'https://openalex.org/W4367296998', 'https://openalex.org/W3151758858', 'https://openalex.org/W2998865368', 'https://openalex.org/W2766311860', 'https://openalex.org/W2467398483', 'https://openalex.org/W2414195533', 'https://openalex.org/W2372740194'], 'abstract_inverted_index': {'The': [0], 'use': [1, 112, 142], 'of': [2, 16, 29, 32, 58, 65, 96, 113, 128, 143], 'taxanes': [3, 17, 115, 144], 'in': [4, 18, 51, 81, 91, 105, 116, 145], 'early': [5, 54, 119, 146], 'breast': [6, 55, 120, 147], 'cancer': [7, 121], 'is': [8, 24], 'increasing.': [9], 'However,': [10], 'there': [11], 'are': [12, 136], 'few': [13], 'mature': [14], 'studies': [15], 'this': [19], 'setting,': [20], 'and': [21, 86, 94, 122, 131], 'their': [22], 'role': [23], 'uncertain.': [25], 'Our': [26], 'systematic': [27], 'review': [28], 'randomised': [30], 'trials': [31, 41, 61, 78, 93, 100, 130, 135], 'adjuvant': [33, 77, 114], 'or': [34], 'neoadjuvant': [35, 60], 'systemic': [36], 'therapy': [37], 'identified': [38], 'ten': [39], 'reported': [40], 'comparing': [42], 'a': [43, 47, 102], 'taxane-containing': [44], 'group': [45, 50], 'with': [46, 53, 68, 84, 118], 'non-taxane-containing': [48], 'control': [49], 'women': [52, 117], 'cancer.': [56, 148], 'Four': [57], 'five': [59, 76], 'showed': [62, 79, 101], 'higher': [63], 'rates': [64], 'complete': [66], 'response': [67], 'taxanes,': [69, 85], 'although': [70], 'differences': [71], 'were': [72, 89], 'not': [73], 'significant.': [74], 'All': [75], 'improvements': [80, 88], 'disease-free': [82], 'survival': [83], 'these': [87, 129], 'significant': [90, 103], 'three': [92], 'independent': [95], 'oestrogen-receptor': [97], 'status.': [98], 'Two': [99], 'improvement': [104], 'overall': [106], 'survival.': [107], 'These': [108], 'results': [109, 132], 'support': [110], 'the': [111, 140], 'involved': [123], 'lymph': [124], 'nodes.': [125], 'Longer': [126], 'follow-up': [127], 'from': [133], 'continuing': [134], 'needed': [137], 'to': [138], 'clarify': [139], 'best': [141]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2083907066', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-31T21:56:40.051033', 'created_date': '2016-06-24'}