Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2083891344', 'doi': 'https://doi.org/10.1185/030079905x38222', 'title': 'Intraocular pressure lowering effect of brinzolamide 1.0% as adjunctive therapy to latanoprost 0.005% in patients with open angle glaucoma or ocular hypertension: an uncontrolled, open-label study', 'display_name': 'Intraocular pressure lowering effect of brinzolamide 1.0% as adjunctive therapy to latanoprost 0.005% in patients with open angle glaucoma or ocular hypertension: an uncontrolled, open-label study', 'publication_year': 2005, 'publication_date': '2005-04-01', 'ids': {'openalex': 'https://openalex.org/W2083891344', 'doi': 'https://doi.org/10.1185/030079905x38222', 'mag': '2083891344', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15899098'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1185/030079905x38222', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206643269', 'display_name': 'Current Medical Research and Opinion', 'issn_l': '0300-7995', 'issn': ['0300-7995', '1473-4877'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050101640', 'display_name': 'Nobuyuki Shoji', 'orcid': 'https://orcid.org/0000-0002-3719-0376'}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}, {'id': 'https://openalex.org/I4210111955', 'display_name': 'Kitasato University Hospital', 'ror': 'https://ror.org/02b3e2815', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111955']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Nobuyuki Shoji', 'raw_affiliation_strings': ['Department of Ophthalmology, Kitasato University Hospital, School of Medicine, Kanagawa, Japan', 'Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I64189623']}, {'raw_affiliation_string': 'Department of Ophthalmology, Kitasato University Hospital, School of Medicine, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I4210111955']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103351809', 'display_name': 'Hiroko Ogata', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149722', 'display_name': 'Musashino Red Cross Hospital', 'ror': 'https://ror.org/05bz4s011', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799517759', 'https://openalex.org/I4210149722']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroko Ogata', 'raw_affiliation_strings': ['Department of Ophthalmology, Musashino Red Cross Hospital, Musashino, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Musashino Red Cross Hospital, Musashino, Japan', 'institution_ids': ['https://openalex.org/I4210149722']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048128405', 'display_name': 'Hideo Suyama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139667', 'display_name': 'International University Of Health And Welfare Atami Hospital', 'ror': 'https://ror.org/04gr92547', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210139667']}, {'id': 'https://openalex.org/I79072001', 'display_name': 'International University of Health and Welfare', 'ror': 'https://ror.org/053d3tv41', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I79072001']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hideo Suyama', 'raw_affiliation_strings': ['Department of Ophthalmology, International University of Health and Welfare Atami Hospital, Shizuoka, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, International University of Health and Welfare Atami Hospital, Shizuoka, Japan', 'institution_ids': ['https://openalex.org/I4210139667', 'https://openalex.org/I79072001']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105696308', 'display_name': 'Hitoshi Ishikawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210139667', 'display_name': 'International University Of Health And Welfare Atami Hospital', 'ror': 'https://ror.org/04gr92547', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I4210139667']}, {'id': 'https://openalex.org/I79072001', 'display_name': 'International University of Health and Welfare', 'ror': 'https://ror.org/053d3tv41', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I79072001']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hitoshi Ishikawa', 'raw_affiliation_strings': ['Department of Ophthalmology, International University of Health and Welfare Atami Hospital, Shizuoka, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, International University of Health and Welfare Atami Hospital, Shizuoka, Japan', 'institution_ids': ['https://openalex.org/I4210139667', 'https://openalex.org/I79072001']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035101365', 'display_name': 'Hiromasa Suzuki', 'orcid': 'https://orcid.org/0000-0003-4237-1101'}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiromasa Suzuki', 'raw_affiliation_strings': ['Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102031259', 'display_name': 'Tetsuya Morita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsuya Morita', 'raw_affiliation_strings': ['Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025029043', 'display_name': 'Hiromi Kawai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiromi Kawai', 'raw_affiliation_strings': ['Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Orthoptics and Visual Science, Kitasato University, School of Allied Health Sciences, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063681210', 'display_name': 'Hiroyuki Nishimoto', 'orcid': 'https://orcid.org/0000-0003-3256-775X'}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroyuki Nishimoto', 'raw_affiliation_strings': ['Department of Ophthalmology, Sagamihara Kyodo Hospital, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Sagamihara Kyodo Hospital, Kanagawa, Japan', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089419266', 'display_name': 'Tetsu Nemoto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210146782', 'display_name': 'Ebina General Hospital', 'ror': 'https://ror.org/04j3mpm77', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210146782']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsu Nemoto', 'raw_affiliation_strings': ['Department of Ophthalmology, Ebina Sogo Hospital, Sendai, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Ebina Sogo Hospital, Sendai, Japan', 'institution_ids': ['https://openalex.org/I4210146782']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082335827', 'display_name': 'Kimiya Shimizu', 'orcid': 'https://orcid.org/0000-0001-5833-5602'}, 'institutions': [{'id': 'https://openalex.org/I4210111955', 'display_name': 'Kitasato University Hospital', 'ror': 'https://ror.org/02b3e2815', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111955']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kimiya Shimizu', 'raw_affiliation_strings': ['Department of Ophthalmology, Kitasato University Hospital, School of Medicine, Kanagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Kitasato University Hospital, School of Medicine, Kanagawa, Japan', 'institution_ids': ['https://openalex.org/I4210111955']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5050101640'], 'corresponding_institution_ids': ['https://openalex.org/I64189623', 'https://openalex.org/I4210111955'], 'apc_list': None, 'apc_paid': None, 'fwci': 4.125, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 37, 'citation_normalized_percentile': {'value': 0.869232, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '21', 'issue': '4', 'first_page': '503', 'last_page': '507'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10250', 'display_name': 'Global Prevalence and Treatment of Glaucoma', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10250', 'display_name': 'Global Prevalence and Treatment of Glaucoma', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11538', 'display_name': "Pathophysiology and Management of Graves' Ophthalmopathy", 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10997', 'display_name': 'Diagnosis and Management of Dry Eye Disease', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/intraocular-pressure', 'display_name': 'Intraocular Pressure', 'score': 0.637617}, {'id': 'https://openalex.org/keywords/ocular-hypertension', 'display_name': 'Ocular Hypertension', 'score': 0.574587}, {'id': 'https://openalex.org/keywords/primary-open-angle-glaucoma', 'display_name': 'Primary Open-Angle Glaucoma', 'score': 0.505913}, {'id': 'https://openalex.org/keywords/regimen', 'display_name': 'Regimen', 'score': 0.48368603}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9547017}, {'id': 'https://openalex.org/C2776740260', 'wikidata': 'https://www.wikidata.org/wiki/Q634959', 'display_name': 'Latanoprost', 'level': 3, 'score': 0.91441715}, {'id': 'https://openalex.org/C2778527774', 'wikidata': 'https://www.wikidata.org/wiki/Q159701', 'display_name': 'Glaucoma', 'level': 2, 'score': 0.82907575}, {'id': 'https://openalex.org/C2781092963', 'wikidata': 'https://www.wikidata.org/wiki/Q650050', 'display_name': 'Intraocular pressure', 'level': 2, 'score': 0.7929789}, {'id': 'https://openalex.org/C2776521421', 'wikidata': 'https://www.wikidata.org/wiki/Q9294051', 'display_name': 'Ocular hypertension', 'level': 3, 'score': 0.7922816}, {'id': 'https://openalex.org/C118487528', 'wikidata': 'https://www.wikidata.org/wiki/Q161437', 'display_name': 'Ophthalmology', 'level': 1, 'score': 0.66569865}, {'id': 'https://openalex.org/C2991803831', 'wikidata': 'https://www.wikidata.org/wiki/Q159701', 'display_name': 'Open angle glaucoma', 'level': 3, 'score': 0.60735184}, {'id': 'https://openalex.org/C2781413609', 'wikidata': 'https://www.wikidata.org/wiki/Q7308373', 'display_name': 'Regimen', 'level': 2, 'score': 0.48368603}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.23256624}], 'mesh': [{'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D002257', 'descriptor_name': 'Carbonic Anhydrase Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D005902', 'descriptor_name': 'Glaucoma, Open-Angle', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D007429', 'descriptor_name': 'Intraocular Pressure', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D009798', 'descriptor_name': 'Ocular Hypertension', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D011461', 'descriptor_name': 'Prostaglandins F, Synthetic', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D013843', 'descriptor_name': 'Thiazines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000959', 'descriptor_name': 'Antihypertensive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002257', 'descriptor_name': 'Carbonic Anhydrase Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D002257', 'descriptor_name': 'Carbonic Anhydrase Inhibitors', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D002257', 'descriptor_name': 'Carbonic Anhydrase Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002257', 'descriptor_name': 'Carbonic Anhydrase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005902', 'descriptor_name': 'Glaucoma, Open-Angle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007429', 'descriptor_name': 'Intraocular Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077338', 'descriptor_name': 'Latanoprost', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009798', 'descriptor_name': 'Ocular Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009883', 'descriptor_name': 'Ophthalmic Solutions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011461', 'descriptor_name': 'Prostaglandins F, Synthetic', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011461', 'descriptor_name': 'Prostaglandins F, Synthetic', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D011461', 'descriptor_name': 'Prostaglandins F, Synthetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011461', 'descriptor_name': 'Prostaglandins F, Synthetic', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D013843', 'descriptor_name': 'Thiazines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D013843', 'descriptor_name': 'Thiazines', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D013843', 'descriptor_name': 'Thiazines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013843', 'descriptor_name': 'Thiazines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1185/030079905x38222', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206643269', 'display_name': 'Current Medical Research and Opinion', 'issn_l': '0300-7995', 'issn': ['0300-7995', '1473-4877'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15899098', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.76, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 7, 'referenced_works': ['https://openalex.org/W1966093962', 'https://openalex.org/W1982818379', 'https://openalex.org/W2029444159', 'https://openalex.org/W2032127638', 'https://openalex.org/W2039294698', 'https://openalex.org/W2118634071', 'https://openalex.org/W2615609614'], 'related_works': ['https://openalex.org/W4232952600', 'https://openalex.org/W2117309546', 'https://openalex.org/W2089951399', 'https://openalex.org/W2064925055', 'https://openalex.org/W2051129029', 'https://openalex.org/W2006403852', 'https://openalex.org/W1991910143', 'https://openalex.org/W1989906599', 'https://openalex.org/W1981684730', 'https://openalex.org/W1971101063'], 'abstract_inverted_index': {'Purpose:': [0], 'A': [1], 'prospective': [2], 'study': [3, 157], 'was': [4, 110, 130, 188, 193, 206, 215], 'conducted': [5], 'to': [6, 87, 208, 231], 'evaluate': [7], 'the': [8, 88, 152, 156, 160, 209], 'intraocular': [9, 239], 'pressure': [10, 240], '(IOP)': [11], 'lowering': [12], 'effect': [13], 'of': [14, 93, 127, 199, 212, 229], 'brinzolamide': [15, 65, 86, 205, 230], '1.0%': [16], 'ophthalmic': [17, 26], 'suspension': [18], 'as': [19, 97], 'an': [20], 'adjunctive': [21, 64], 'therapy': [22, 128, 187], 'with': [23, 30, 41, 80, 159, 243], 'latanoprost': [24, 54, 233], '0.005%': [25, 55, 234], 'solution': [27], 'in': [28, 148, 170, 177, 195, 217, 241], 'patients': [29, 40, 242], 'open': [31, 42, 244], 'angle': [32, 43, 245], 'glaucoma': [33, 44, 246], 'or': [34, 46, 247], 'ocular': [35, 47, 248], 'hypertension.Patients': [36], 'and': [37, 75, 100, 124, 139, 176, 186], 'methods:': [38], 'Fourteen': [39], '(OAG)': [45], 'hypertension': [48], '(OH)': [49], 'who': [50], 'had': [51, 201], 'been': [52], 'using': [53], 'for': [56], 'more': [57], 'than': [58], '6': [59], 'months': [60, 77, 126], 'were': [61, 78, 104, 184, 224], 'initiated': [62], 'on': [63], 'therapy.': [66], 'The': [67, 91, 107, 227], 'IOP': [68, 109, 129, 149], 'values': [69], 'at': [70, 150], '1': [71, 120, 174], 'month,': [72, 121], '2': [73, 122, 180], 'months,': [74, 123], '3': [76, 125, 196], 'compared': [79, 158], 'those': [81], 'measured': [82], 'immediately': [83], 'before': [84, 204], 'adding': [85], 'regimen': [89, 235], '(baseline).': [90], 'incidence': [92], 'adverse': [94], 'events': [95], 'such': [96], 'conjunctival': [98], 'hyperemia': [99, 168], 'corneal': [101], 'epithelial': [102], 'defect': [103, 192, 203], 'also': [105], 'examined.Results:': [106], 'baseline': [108, 161], '21.1': [111], '±': [112, 116, 132, 136, 141], '4.8': [113], 'mmHg': [114], '(mean': [115], 'standard': [117], 'deviation).': [118], 'After': [119], '16.9': [131], '4.5': [133], 'mmHg,': [134, 138, 143], '16.6': [135], '4.0': [137], '15.9': [140], '3.1': [142], 'respectively,': [144], 'showing': [145], 'significant': [146], 'reductions': [147], 'all': [151], 'measuring': [153], 'time-points': [154], 'during': [155], 'value': [162], '(': [163], 'p': [164], '<': [165], '0.01).': [166], 'Conjunctival': [167], 'developed': [169], 'one': [171, 218], 'patient': [172], 'after': [173, 179], 'month': [175], 'another': [178], 'months;': [181], 'however,': [182], 'both': [183], 'mild,': [185], 'continued.': [189], 'Corneal': [190], 'epithelium': [191], 'observed': [194], 'patients.': [197], 'One': [198], 'them': [200], 'mild': [202], 'added': [207], 'regimen.': [210], 'Increase': [211], 'eye': [213], 'discharge': [214], 'seen': [216], 'patient.': [219], 'No': [220], 'serious': [221], 'side': [222], 'effects': [223], 'otherwise': [225], 'observed.Conclusion:': [226], 'addition': [228], 'a': [232], 'may': [236], 'further': [237], 'lower': [238], 'hypertension.': [249]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2083891344', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-31T21:56:35.829652', 'created_date': '2016-06-24'}