Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2083880685', 'doi': 'https://doi.org/10.1007/s00894-005-0234-0', 'title': 'Structure of glutathione S-transferase of the filarial parasite Wuchereria bancrofti: a target for drug development against adult worm', 'display_name': 'Structure of glutathione S-transferase of the filarial parasite Wuchereria bancrofti: a target for drug development against adult worm', 'publication_year': 2005, 'publication_date': '2005-04-28', 'ids': {'openalex': 'https://openalex.org/W2083880685', 'doi': 'https://doi.org/10.1007/s00894-005-0234-0', 'mag': '2083880685', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15864673'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00894-005-0234-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113170167', 'display_name': 'Journal of Molecular Modeling', 'issn_l': '0948-5023', 'issn': ['0948-5023', '1610-2940'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015478127', 'display_name': 'Sivaramakrishnan Thirumalai Nathan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210144797', 'display_name': 'Vector Control Research Centre', 'ror': 'https://ror.org/04ds2ap82', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I37048141', 'https://openalex.org/I4210144797']}, {'id': 'https://openalex.org/I37048141', 'display_name': 'Indian Council of Medical Research', 'ror': 'https://ror.org/0492wrx28', 'country_code': 'IN', 'type': 'government', 'lineage': ['https://openalex.org/I37048141']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sivaramakrishnan Thirumalai Nathan', 'raw_affiliation_strings': ['Vector Control Research Centre (Indian Council of Medical Research), Indira Nagar, Pondicherry, 605006, India'], 'affiliations': [{'raw_affiliation_string': 'Vector Control Research Centre (Indian Council of Medical Research), Indira Nagar, Pondicherry, 605006, India', 'institution_ids': ['https://openalex.org/I4210144797', 'https://openalex.org/I37048141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050985773', 'display_name': 'Nisha Mathew', 'orcid': 'https://orcid.org/0000-0002-2313-4787'}, 'institutions': [{'id': 'https://openalex.org/I37048141', 'display_name': 'Indian Council of Medical Research', 'ror': 'https://ror.org/0492wrx28', 'country_code': 'IN', 'type': 'government', 'lineage': ['https://openalex.org/I37048141']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Nisha Mathew', 'raw_affiliation_strings': ['Vector Control Research Centre, Indian Council of Medical Research, India'], 'affiliations': [{'raw_affiliation_string': 'Vector Control Research Centre, Indian Council of Medical Research, India', 'institution_ids': ['https://openalex.org/I37048141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113993091', 'display_name': 'Muthuswami Kalyanasundaram', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I37048141', 'display_name': 'Indian Council of Medical Research', 'ror': 'https://ror.org/0492wrx28', 'country_code': 'IN', 'type': 'government', 'lineage': ['https://openalex.org/I37048141']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Muthuswami Kalyanasundaram', 'raw_affiliation_strings': ['Vector Control Research Centre, Indian Council of Medical Research, India'], 'affiliations': [{'raw_affiliation_string': 'Vector Control Research Centre, Indian Council of Medical Research, India', 'institution_ids': ['https://openalex.org/I37048141']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5063789476', 'display_name': 'K Balaraman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I37048141', 'display_name': 'Indian Council of Medical Research', 'ror': 'https://ror.org/0492wrx28', 'country_code': 'IN', 'type': 'government', 'lineage': ['https://openalex.org/I37048141']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Kothandapani Balaraman', 'raw_affiliation_strings': ['Vector Control Research Centre, Indian Council of Medical Research, India'], 'affiliations': [{'raw_affiliation_string': 'Vector Control Research Centre, Indian Council of Medical Research, India', 'institution_ids': ['https://openalex.org/I37048141']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2890, 'currency': 'EUR', 'value_usd': 3690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.496, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.623697, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '11', 'issue': '3', 'first_page': '194', 'last_page': '199'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12187', 'display_name': 'Glutathione Transferases and Polymorphisms', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12187', 'display_name': 'Glutathione Transferases and Polymorphisms', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11332', 'display_name': 'Genomics, phytochemicals, and oxidative stress', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12412', 'display_name': 'Enzyme function and inhibition', 'score': 0.989, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ramachandran-plot', 'display_name': 'Ramachandran plot', 'score': 0.9087229}, {'id': 'https://openalex.org/keywords/protein-data-bank', 'display_name': 'Protein Data Bank', 'score': 0.53743446}, {'id': 'https://openalex.org/keywords/homology', 'display_name': 'Homology', 'score': 0.49307773}], 'concepts': [{'id': 'https://openalex.org/C14301744', 'wikidata': 'https://www.wikidata.org/wiki/Q579211', 'display_name': 'Ramachandran plot', 'level': 3, 'score': 0.9087229}, {'id': 'https://openalex.org/C65556437', 'wikidata': 'https://www.wikidata.org/wiki/Q766195', 'display_name': 'Protein Data Bank (RCSB PDB)', 'level': 2, 'score': 0.8509661}, {'id': 'https://openalex.org/C169627665', 'wikidata': 'https://www.wikidata.org/wiki/Q5767913', 'display_name': 'Homology modeling', 'level': 3, 'score': 0.80193794}, {'id': 'https://openalex.org/C2778672586', 'wikidata': 'https://www.wikidata.org/wiki/Q311109', 'display_name': 'Wuchereria bancrofti', 'level': 4, 'score': 0.76839423}, {'id': 'https://openalex.org/C119145174', 'wikidata': 'https://www.wikidata.org/wiki/Q7251429', 'display_name': 'Protein Data Bank', 'level': 3, 'score': 0.53743446}, {'id': 'https://openalex.org/C165525559', 'wikidata': 'https://www.wikidata.org/wiki/Q224180', 'display_name': 'Homology (biology)', 'level': 3, 'score': 0.49307773}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.46059692}, {'id': 'https://openalex.org/C47701112', 'wikidata': 'https://www.wikidata.org/wiki/Q735188', 'display_name': 'Protein structure', 'level': 2, 'score': 0.35556248}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.3264637}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23350367}, {'id': 'https://openalex.org/C90856448', 'wikidata': 'https://www.wikidata.org/wiki/Q431', 'display_name': 'Zoology', 'level': 1, 'score': 0.20174336}, {'id': 'https://openalex.org/C165901193', 'wikidata': 'https://www.wikidata.org/wiki/Q3129936', 'display_name': 'Helminths', 'level': 2, 'score': 0.19218406}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.104619265}, {'id': 'https://openalex.org/C2777629521', 'wikidata': 'https://www.wikidata.org/wiki/Q815753', 'display_name': 'Filariasis', 'level': 3, 'score': 0.085789144}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0734725}], 'mesh': [{'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D015801', 'descriptor_name': 'Helminth Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D014958', 'descriptor_name': 'Wuchereria bancrofti', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000596', 'descriptor_name': 'Amino Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000969', 'descriptor_name': 'Antinematodal Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015195', 'descriptor_name': 'Drug Design', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005978', 'descriptor_name': 'Glutathione', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005978', 'descriptor_name': 'Glutathione', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015801', 'descriptor_name': 'Helminth Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012984', 'descriptor_name': 'Software', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014958', 'descriptor_name': 'Wuchereria bancrofti', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00894-005-0234-0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113170167', 'display_name': 'Journal of Molecular Modeling', 'issn_l': '0948-5023', 'issn': ['0948-5023', '1610-2940'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15864673', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.44, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1508885706', 'https://openalex.org/W1552327728', 'https://openalex.org/W1599674963', 'https://openalex.org/W1969148232', 'https://openalex.org/W1986191025', 'https://openalex.org/W1986532204', 'https://openalex.org/W1998676514', 'https://openalex.org/W2015642465', 'https://openalex.org/W2018433666', 'https://openalex.org/W2025089555', 'https://openalex.org/W2033014465', 'https://openalex.org/W2034523565', 'https://openalex.org/W2046645767', 'https://openalex.org/W2049902088', 'https://openalex.org/W2051831487', 'https://openalex.org/W2056063819', 'https://openalex.org/W2065283382', 'https://openalex.org/W2066142272', 'https://openalex.org/W2074251084', 'https://openalex.org/W2075356247', 'https://openalex.org/W2078057889', 'https://openalex.org/W2088933990', 'https://openalex.org/W2089844646', 'https://openalex.org/W2106154817', 'https://openalex.org/W2106882534', 'https://openalex.org/W2157165549', 'https://openalex.org/W2158714788', 'https://openalex.org/W2160223767', 'https://openalex.org/W2165795960'], 'related_works': ['https://openalex.org/W3183750506', 'https://openalex.org/W2504812601', 'https://openalex.org/W2324570860', 'https://openalex.org/W2167450757', 'https://openalex.org/W2090630809', 'https://openalex.org/W2088162897', 'https://openalex.org/W2083880685', 'https://openalex.org/W2062024796', 'https://openalex.org/W2020669016', 'https://openalex.org/W1990760938'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2083880685', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2025-01-09T18:48:41.908735', 'created_date': '2016-06-24'}