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4198, 4204, 4238, 4299, 4303, 4317, 4321, 4394, 4411, 4425, 4429], 'plastidic': [5, 87, 144, 226, 925, 1026, 1359, 1963, 2020, 2101, 2113, 2191, 2311, 2408, 3385, 3422, 3485, 3636], '2C-methyl-d-erythritol': [6, 145, 289, 768], '4-phosphate': [7, 146, 290], '(MEP)': [8, 147], 'pathway': [9, 33, 119, 148, 172, 258, 675, 758, 926, 1031, 1075, 1087, 1099, 1410, 2119, 2245, 2260, 2344, 2358, 2511, 2578, 2601, 2609, 2779, 2841, 3414, 3638, 3786, 4006, 4305, 4323], 'that': [10, 41, 98, 126, 149, 180, 237, 265, 308, 531, 662, 929, 1015, 1840, 1942, 2041, 2075, 2089, 2120, 2128, 2142, 2164, 2272, 2441, 2482, 2497, 2620, 2714, 2733, 2768, 2792, 2804, 2838, 2853, 2866, 2877, 2902, 3284, 3408, 3434, 3482, 3513, 3634, 3675, 3908, 3927, 3941, 4096, 4200, 4420], 'produces': [11, 150, 927], 'isopentenyl': [12, 121, 132, 151, 260, 271, 284, 634], 'diphosphate': [13, 133, 152, 272, 285, 287, 635, 641], 'is': [14, 120, 134, 153, 259, 273, 503, 615, 717, 774, 930, 1013, 1116, 1356, 1446, 1565, 1775, 1792, 1944, 1977, 2091, 2143, 2261, 2288, 2313, 2345, 2400, 2413, 2440, 2460, 2484, 2495, 2552, 2623, 2630, 2682, 2770, 2849, 2912, 3289, 3406, 3415, 3633, 3906, 4082, 4094, 4326], 'catalyzed': [15, 154, 1117], 'by': [16, 155, 628, 1118, 1353, 1453, 1572, 1979, 2137, 2185, 2346, 2442, 2685, 3073, 3221, 4383], '1-deoxy-d-xylulose-5-phosphate': [17, 24, 93, 156, 163, 232, 282, 291, 1112], 'synthase.': [18, 157], 'To': [19, 158, 2570], 'investigate': [20, 159], 'whether': [21, 160, 2391], 'or': [22, 43, 161, 182, 1816, 2030, 2190, 2512, 2938, 2956, 3336, 3381, 3459, 3552, 3605, 3716, 3868, 3926, 4099, 4215, 4405], 'not': [23, 162, 2518, 2631, 3471, 3574, 3583, 3845, 3865, 3918, 4046], 'synthase': [25, 94, 164, 233, 283, 1120], 'catalyzes': [26, 101, 165, 240, 4422], 'a': [27, 166, 302, 334, 372, 506, 1101, 1785, 1808, 1945, 2116, 2289, 2342, 2401, 2520, 2625, 2818, 3378, 3445, 3659, 3685, 3722, 3928, 3942, 4083, 4234, 4397], 'limiting': [28, 135, 167, 274, 1797, 2095, 2290, 2314, 2402, 2488, 2532, 2573, 2626, 2717, 2725, 2736, 2774, 3290, 3417, 3425, 3525, 4318, 4426], 'in': [30, 34, 77, 92, 127, 169, 173, 216, 231, 266, 310, 325, 333, 509, 535, 663, 737, 765, 771, 777, 1020, 1072, 1096, 1130, 1358, 1365, 1432, 1582, 1770, 1799, 1804, 1869, 1962, 1966, 1973, 2019, 2023, 2032, 2077, 2097, 2107, 2145, 2183, 2235, 2246, 2257, 2315, 2321, 2353, 2365, 2384, 2395, 2471, 2477, 2490, 2507, 2525, 2540, 2548, 2562, 2614, 2758, 2762, 2776, 2785, 2807, 2821, 2827, 2872, 3079, 3092, 3110, 3208, 3274, 3375, 3383, 3392, 3399, 3430, 3448, 3507, 3533, 3549, 3553, 3562, 3575, 3593, 3602, 3629, 3654, 3669, 3678, 3690, 3702, 3725, 3730, 3861, 3870, 3913, 3924, 3958, 3979, 4002, 4040, 4042, 4069, 4123, 4133, 4190, 4203, 4212, 4226, 4302, 4327, 4387, 4393, 4407, 4435], 'MEP': [32, 109, 118, 171, 248, 257, 757, 1086, 1098, 1409, 1452, 1564, 1865, 2192, 2244, 2259, 2294, 2397, 2492, 2510, 2577, 2600, 2608, 2778, 2861, 2881, 3413, 4304, 4322, 4430], 'plants,': [35, 51, 174, 190, 330, 1349, 2024, 3875, 4307], 'we': [36, 96, 175, 235, 1950, 2415, 2480, 2516, 2789, 3369, 3673, 3863, 4308, 4418], 'produced': [37, 176, 750, 1352, 2144, 2182, 2825, 3653], 'transgenic': [38, 53, 72, 177, 192, 211, 2038, 3540, 3571, 3631, 3838, 3915, 4110, 4205, 4243, 4388], 'Arabidopsis': [39, 178, 1298, 2033, 3925], 'plants': [40, 54, 73, 179, 193, 212, 664, 1021, 1436, 2042, 2059, 2184, 2781, 3376, 3541, 3572, 3656, 3756, 3766, 3839, 3948, 4111, 4227], 'over-': [42, 181], 'underexpress': [44, 183], 'this': [45, 99, 184, 238, 317, 1354, 1948, 2385, 2549, 2787, 2910, 3599, 4381], 'enzyme.': [46, 185], 'Compared': [47, 186], 'with': [48, 90, 187, 229, 719, 1814, 2060, 3095, 3490, 3757, 3991], 'non-transgenic': [49, 188], 'wild-type': [50, 189], 'accumulate': [55, 194], 'different': [56, 195, 1767, 3456], 'levels': [57, 84, 196, 223, 2027, 2047, 2062, 2079, 2449, 2465, 2473, 2564, 2597, 2798, 2829, 2959, 3076, 3094, 3121, 3394, 3453, 3595, 3910, 4386, 4395, 4409, 4412, 4437], 'various': [59, 198, 652, 2084, 3468], 'isoprenoids': [60, 88, 199, 227, 331, 395, 407, 580, 653, 1036, 2049, 2106, 2114, 2148, 2170, 2451, 2546, 2791, 2803, 3124, 3386, 3403, 3443, 3457, 3469, 3499, 4209, 4231], 'such': [61, 200, 340, 583, 746, 946, 1784, 2050, 2150, 2799, 2810, 3307], 'as': [62, 201, 341, 505, 541, 584, 747, 947, 1362, 1364, 1580, 2051, 2515, 2624, 2782, 2784, 2800, 2811, 3216, 3308, 4051, 4053, 4088, 4090, 4324], 'chlorophylls,': [63, 202, 2052], 'tocopherols,': [64, 203, 2053], 'carotenoids,': [65, 204, 941, 2054], 'abscisic': [66, 205, 278], 'acid,': [67, 206], 'and': [68, 79, 207, 218, 350, 361, 370, 385, 402, 411, 587, 612, 621, 637, 721, 743, 773, 781, 943, 949, 1025, 1107, 1128, 1297, 1370, 1420, 1435, 1921, 2056, 2152, 2178, 2280, 2359, 2430, 2454, 2527, 2557, 2590, 2628, 2802, 2813, 3009, 3192, 3365, 3526, 3538, 3569, 3693, 3727, 3742, 3956, 3967, 4034, 4074, 4118, 4218, 4248, 4402], 'gibberellins.': [69, 208], 'Phenotypically,': [70, 209], 'had': [74, 213, 2045, 2065, 3542, 3767], 'slight': [75, 214], 'alterations': [76, 215, 2076, 2320, 3391, 4189], 'growth': [78, 217, 3564, 3626, 3679, 3930, 4043], 'germination': [80, 219, 3550, 3703, 3769, 3836, 4058], 'rates.': [81, 220, 3770], 'Because': [82, 221, 2468, 3389], 'several': [86, 225, 658, 2037], 'correlate': [89, 228], 'changes': [91, 230, 1803, 2082, 2352, 2364, 2470, 2476, 2524, 3091, 3398, 3532, 3592, 3597, 3689, 4041, 4392, 4434], 'levels,': [95, 234, 1958, 2753, 3368, 4033], 'conclude': [97, 236, 4419], 'enzyme': [100, 239, 1455, 1810, 2026, 2291, 2394], 'one': [102, 241, 1827, 2092, 2485, 2771, 4315, 4423], 'rate-limiting': [105, 244, 1844, 1946, 2339], 'steps': [106, 245, 1406, 1428, 1760, 1798, 2096, 2241, 2255, 2340, 2587, 2775, 3109, 4427], 'biosynthetic': [110, 249, 610, 648, 1787, 2118, 2240, 2343, 2840, 3083, 3112, 3480, 3510, 3518, 3785, 4005], 'pathway.': [111, 250, 1788, 1801, 2285, 2493, 2862, 2882, 4431], 'Furthermore,': [112, 251], 'since': [113, 252, 4207, 4433], 'product': [115, 254, 4078], 'diphosphate,': [122, 261], 'our': [123, 262, 2125, 4219], 'results': [124, 263, 3278, 3772, 3984, 4417], 'suggest': [125, 264, 1941, 2865], 'plastids': [128, 267, 772], 'pool': [130, 269], 'to': [136, 275, 352, 399, 617, 1033, 1110, 1414, 1451, 1762, 1782, 2013, 2081, 2160, 2166, 2266, 2274, 2335, 2350, 2389, 2417, 2475, 2896, 2946, 3118, 3210, 3218, 3310, 3338, 3397, 3435, 3462, 3544, 3585, 3589, 3666, 3684, 3710, 3776, 3834, 3857, 3920, 3935, 3973, 3987, 4067, 4085, 4104, 4221, 4229, 4310], 'isprenoid': [137, 276], 'production.': [138, 277, 2168, 3293], 'acid': [279, 299, 365], '1-deoxy-d-xylulose': [280], '5-phosphate': [281], 'dimethylallyl': [286, 640], 'acetate/mevalonate': [288, 673], 'reductoisomerase': [292, 1457], 'gibberellins': [293, 367], 'polymerase': [294], 'chain': [295, 374], 'reaction': [296, 1104, 1115, 1355, 2254], 'reverse-transcriptase-PCR': [297], '4-morpholineethanesulfonic': [298], 'Isoprenoids': [300], 'are': [301, 323, 415, 538, 626, 749, 2149, 2171, 2181, 2277, 2452, 2463, 2505, 2565, 2588, 2793, 2805, 2856, 3370, 3582, 3681, 3773, 3917, 3985, 4210, 4232], 'group': [303, 319, 2111], 'biologically': [305], 'active': [306, 2898], 'molecules': [307, 2176, 3215, 4087], 'number': [309], 'tens': [312], 'thousands.': [314], 'Members': [315], 'diverse': [318], 'natural': [321], 'products': [322, 582, 2087, 2368, 3304], 'found': [324, 776, 2619, 2713, 3990], 'all': [326, 1067, 2069, 3400], 'organisms.': [327], 'In': [328, 1348, 1860, 2011, 2815, 3294, 3832, 3855], 'higher': [329, 2108], 'participate': [332], 'wide': [335, 4398], 'variety': [336, 4399], 'biological': [338], 'functions': [339, 3100], 'photosynthesis,': [342], 'respiration,': [343], 'growth,': [344, 2429], 'cell': [345], 'cycle': [346], 'control,': [347], 'plant': [348, 394, 1085, 2428, 2509, 3578, 4049], 'defense,': [349], 'adaptation': [351], 'environmental': [353], 'conditions.': [354, 3557, 3854], 'Specific': [355], 'examples': [356], 'include': [357, 581], 'photosynthetic': [358, 3663], 'pigments': [359], '(chlorophylls': [360], 'carotenoids),': [362], 'hormones': [363, 2855, 2962], '(abscisic': [364], '(ABA),1': [366], '(GA),': [368], 'cytokinins,': [369], 'brassinosteroids),': [371], 'side': [373], 'electron': [377], 'transporter': [378], '(plastiquinone),': [379], 'structural': [380], 'components': [381], 'membranes': [383], '(phytosterols),': [384], 'antimicrobial': [386], 'agents': [387, 543], '(phytoalexins).': [388], 'Beyond': [389], 'these': [390, 620, 644, 2071, 2132, 2854, 3102, 3111, 3214, 3280, 3516, 3655, 3874, 3922, 3937, 3947, 4086, 4109, 4403, 4416], 'plant-specific': [391], 'functions,': [392], 'many': [393, 4208], 'have': [396, 400, 1076, 1088, 1125, 1411, 1429, 2156, 2326, 2603, 2951, 3087, 3658], 'been': [397, 1077, 1089, 1126, 1412, 1430, 2157, 2232, 2604, 2611, 2845, 3116], 'shown': [398, 1413, 1581], 'industrial': [401, 4216], 'medical': [403], 'importance.': [404], 'plant-produced': [406, 500], 'β-carotene': [408, 3126, 3311], '(provitamin': [409], 'A)': [410], 'α-tocopherol': [412, 3193, 3339], '(vitamin': [413], 'E)': [414], 'both': [416, 1433, 2816], 'basic': [417], 'nutrients': [418], 'required': [419, 2806, 3934], 'for': [420, 760, 932, 1417, 1424, 1443, 1833, 2435, 2501, 2555, 2718, 2742, 3291, 3418, 3624, 3779, 4197, 4237], 'maintenance': [422], 'human': [424], 'health': [425], '(1Hirschberg': [426], 'J.': [427, 483, 519, 547, 561, 679, 786, 800, 818, 826, 846, 865, 907, 915, 952, 960, 1059, 1271, 1287, 1311, 1462, 1476, 1531, 1535, 1588, 1621, 1656, 1689, 1724, 1895, 1934, 2199, 2640, 2706, 2981, 3064, 3162, 3184, 3240, 3262, 3804, 3898, 4024, 4152, 4262, 4353], 'Curr.': [428, 593, 1848], 'Opin.': [429, 594, 1849], 'Biotechnol.': [430, 467, 3020, 3142, 3327], '1999;': [431, 521, 569, 597, 685, 708, 808, 881, 898, 1046, 1251, 1484, 1522, 1540, 1610, 1879, 2672, 2930, 3001, 3065, 3163, 3241, 3824, 4337], '10:': [432], '186-191Crossref': [433], 'PubMed': [434, 447, 471, 494, 524, 572, 600, 688, 711, 731, 811, 830, 850, 884, 901, 919, 964, 1006, 1049, 1162, 1188, 1214, 1236, 1254, 1275, 1292, 1315, 1343, 1399, 1487, 1510, 1525, 1543, 1559, 1613, 1644, 1681, 1716, 1753, 1855, 1882, 1900, 1916, 1938, 2006, 2225, 2378, 2645, 2661, 2675, 2710, 2933, 2985, 3004, 3024, 3046, 3068, 3146, 3166, 3202, 3244, 3331, 3348, 3808, 3827, 3902, 4028, 4156, 4184, 4266, 4294, 4340, 4358, 4374], 'Scopus': [435, 448, 472, 495, 525, 573, 601, 689, 712, 732, 812, 831, 851, 872, 885, 902, 920, 965, 982, 1007, 1050, 1163, 1189, 1215, 1237, 1255, 1293, 1316, 1344, 1400, 1488, 1511, 1526, 1544, 1560, 1614, 1645, 1682, 1717, 1754, 1856, 1883, 1901, 1917, 2007, 2226, 2646, 2662, 2676, 2934, 3005, 3025, 3047, 3069, 3147, 3188, 3203, 3266, 3332, 3349, 3828, 4157, 4185, 4267, 4295, 4341, 4359, 4375], '(87)': [436], 'Google': [437, 450, 474, 497, 527, 575, 603, 691, 714, 734, 814, 833, 853, 874, 887, 904, 922, 967, 984, 1009, 1052, 1065, 1165, 1191, 1217, 1239, 1257, 1276, 1295, 1318, 1346, 1402, 1490, 1513, 1528, 1546, 1562, 1616, 1647, 1684, 1719, 1756, 1858, 1885, 1903, 1919, 1939, 2009, 2205, 2228, 2379, 2648, 2664, 2678, 2711, 2936, 2986, 3007, 3027, 3049, 3071, 3149, 3167, 3190, 3205, 3245, 3268, 3334, 3351, 3619, 3809, 3830, 3903, 4029, 4159, 4187, 4269, 4297, 4343, 4361, 4377], 'Scholar,': [438, 451, 475, 692, 834, 854, 875, 888, 905, 968, 985, 1053, 1319, 1384, 1491, 1514, 1529, 1547, 1617, 1648, 1685, 1720, 1886, 1904, 2206, 2649, 2665, 2987, 3028, 3050, 3150, 3168, 3246, 3810, 4160, 4270, 4344, 4362], '2Shintani': [439], 'D.': [440, 442, 565, 804, 993, 1201, 1480, 3176, 3182, 3195, 3197, 3254, 3260, 3341, 3343], 'DellaPenna': [441, 3196, 3342], 'Science.': [443, 490, 568, 807, 1483, 3198, 3344], '1998;': [444, 827, 1000, 1185, 1211, 1233, 1507, 1852, 3043, 3199, 3345], '282:': [445, 3200, 3346], '2098-2100Crossref': [446, 3201, 3347], '(436)': [449, 3204, 3350], '3Römer': [452], 'S.': [453, 479, 549, 788, 860, 862, 1140, 1149, 1157, 1183, 1209, 1284, 1394, 1464, 1493, 1505, 1592, 1594, 1608, 1629, 1639, 1654, 1658, 1664, 1676, 1711, 1722, 1728, 1732, 1748, 1892, 2220, 2637, 3128, 3158, 3236, 3313, 4350], 'Fraser': [454, 3129, 3173, 3251, 3314], 'P.D.': [455, 3130, 3174, 3252, 3315], 'Kiano': [456, 3131, 3316], 'J.W.': [457, 3132, 3317], 'Shipton': [458, 3133, 3318], 'C.A.': [459, 1627, 1660, 1697, 1726, 3134, 3319], 'Misawa': [460, 3135, 3320], 'N.': [461, 698, 1169, 1267, 1701, 1930, 2702, 3136, 3321], 'Schuch': [462, 3137, 3322], 'W.': [463, 987, 1248, 1553, 1598, 1623, 1670, 1695, 1736, 1876, 1910, 2212, 2655, 3138, 3323, 4334, 4368], 'Bramley': [464, 2668, 3139, 3179, 3257, 3324], 'P.M.': [465, 2669, 3140, 3180, 3258, 3325], 'Nat.': [466, 878, 3019, 3141, 3326], '2000;': [468, 491, 1272, 1289, 1340, 1556, 1641, 1678, 1713, 1750, 1897, 1913, 1935, 2003, 2222, 2642, 2658, 2707, 2982, 3021, 3143, 3328, 3805, 3899, 4025, 4181, 4291, 4355, 4371], '18:': [469, 3022, 3144, 3329], '666-669Crossref': [470, 3145, 3330], '(350)': [473, 3148, 3333], '4Ye': [476], 'X.': [477], 'Al-Babili': [478], 'Klöti': [480], 'A.': [481, 696, 700, 816, 991, 997, 1158, 1177, 1184, 1210, 1224, 1269, 1323, 1395, 1506, 1600, 1609, 1633, 1640, 1668, 1677, 1705, 1712, 1740, 1749, 1932, 1974, 1986, 2221, 2704, 2977, 2989, 2997, 3172, 3250, 3800, 3812, 3820, 3894, 4020, 4164, 4274], 'Zhang': [482], 'Lucca': [484], 'P.': [485, 487, 840, 1309, 1337, 2000, 3062, 3178, 3256, 4150, 4178, 4260, 4288], 'Beyer': [486], 'Potrykus': [488], 'I.': [489, 557, 796, 1472], '287:': [492], '303-305Crossref': [493], '(1667)': [496], 'Scholar).': [498, 528, 576, 604, 923, 1010, 1347, 1403, 1563, 1757, 1859, 2010, 2229, 2380, 2679, 3620, 3753, 3831, 3904, 4030, 4378], 'Another': [499, 1789], 'isoprenoid,': [501], 'Taxol,': [502], 'used': [504, 931], 'chemotherapeutic': [507], 'agent': [508], 'treatment': [511], 'cancer': [513], '(5Blagosklonny': [514], 'M.V.': [515], 'Fojo': [516], 'T.': [517, 1138, 1246, 1280, 1331, 1495, 1551, 1874, 1888, 1908, 1994, 2210, 2633, 2653, 3018, 4172, 4282, 4332, 4346, 4366], 'Int.': [518], 'Cancer.': [520], '83:': [522], '151-156Crossref': [523], '(333)': [526], 'Moreover,': [529, 2058], 'drugs': [530], 'block': [532], 'isoprenoid': [533, 609, 1835, 1964, 2021, 2085, 2331, 2431, 2438, 2478, 2504, 2833, 3292, 3302, 3431, 3439, 3479, 3534, 4116, 4408], 'production': [534, 1367, 1445, 2099, 2317, 2406, 2720, 3420, 3432, 4239], 'Plasmodium': [536], 'falciparum': [537], 'being': [539], 'evaluated': [540], 'anti-malarial': [542], '(6Jomaa': [544, 783, 1459], 'H.': [545, 784, 844, 864, 1151, 1286, 1327, 1333, 1460, 1497, 1499, 1650, 1691, 1730, 1894, 1990, 1996, 2639, 3036, 4168, 4174, 4278, 4284, 4352], 'Wiesner': [546, 785, 1461], 'Sanderbrand': [548, 787, 1463], 'Altincicek': [550, 789, 1465], 'B.': [551, 790, 842, 1230, 1244, 1466, 1549, 1872, 1906, 2651, 2995, 3818, 4330, 4364], 'Weidemeyer': [552, 791, 1467], 'C.': [553, 792, 820, 1226, 1325, 1374, 1468, 1533, 1988, 2991, 3814, 4166, 4276], 'Hintz': [554, 793, 1469], 'M.': [555, 559, 794, 798, 824, 836, 838, 856, 858, 877, 909, 913, 954, 958, 989, 995, 1057, 1175, 1263, 1282, 1307, 1470, 1474, 1590, 1662, 1693, 1699, 1734, 1890, 1926, 2197, 2635, 2667, 2698, 3014, 3156, 3234, 3733, 4148, 4258, 4348], 'Türbachova': [556, 795, 1471], 'Eberl': [558, 797, 1473], 'Zeidler': [560, 799, 1475, 1534], 'Lichtenthaler': [562, 801, 821, 910, 955, 971, 975, 1477, 1536], 'H.K.': [563, 802, 822, 890, 911, 956, 972, 1038, 1055, 1478, 1537, 2195, 2922], 'Soldati': [564, 803, 1479], 'Beck': [566, 805, 1481], 'E.': [567, 806, 1482, 2993, 3816], '285:': [570, 809, 1485], '1573-1576Crossref': [571, 810, 1486], '(1021)': [574, 813, 1489], 'Industrial': [577], 'uses': [578, 623], 'colorants,': [585], 'fragrances,': [586], 'flavorings': [588], '(7Lange': [589], 'B.M.': [590, 1197, 1516, 2208], 'Croteau': [591, 1202, 1517, 2213], 'R.': [592, 1203, 1375, 1388, 1518, 2214, 3058], 'Plant': [595, 893, 895, 1041, 1043, 1231, 1270, 1310, 1338, 1850, 1933, 2001, 2373, 2705, 2925, 2927, 2980, 2998, 3041, 3063, 3161, 3183, 3239, 3261, 3803, 3821, 3897, 4023, 4151, 4179, 4261, 4289], 'Biol.': [596, 684, 707, 897, 999, 1045, 1851, 2929, 3000, 3823], '2:': [598], '139-144Crossref': [599], '(93)': [602], 'A': [605, 3621], 'detailed': [606, 3944], 'understanding': [607, 2268], 'pathways': [611, 649, 667, 2133, 2163, 2193, 2439, 3481, 3519, 3668, 4225], 'their': [613, 2167, 2563, 3080, 3508, 4439], 'regulation': [614, 3955, 3964], 'essential': [616, 2153], 'fully': [618, 2267], 'exploit': [619], 'future': [622], 'isoprenoids.Isoprenoids': [625], 'derived': [627, 2172], 'consecutive': [629, 1574], 'condensations': [630], 'five-carbon': [632], 'precursors,': [633, 646], '(IPP)': [636], 'its': [638, 2298, 2423, 2528, 3521, 3640], 'isomer': [639], '(DMAPP).': [642], 'From': [643, 4415], 'common': [645], 'diverge.': [654], 'work': [656, 1780, 1970, 2687, 2788], 'groups': [659, 2950], 'has': [660, 2115, 2231, 2610, 2844, 3115, 3520], 'demonstrated': [661, 1971], 'two': [665], 'distinct': [666, 2117], 'synthesize': [668], 'IPP': [669, 928, 1360, 1418, 1444, 1763, 1774, 2102, 2141, 2177, 2312, 2323, 2740, 2876, 2907, 2911, 2920, 3288, 3367, 3410, 3428, 3449, 3637, 3652], '(Fig.': [670, 751, 1091, 1437], '1).': [671, 752, 1092, 1438], '(MVA)': [674], '(8Newman': [676], 'J.D.': [677], 'Chappell': [678], 'Crit.': [680, 703], 'Rev.': [681, 704, 892, 1040, 2924], 'Biochem.': [682, 705, 825, 845, 914, 959, 1520], 'Mol.': [683, 706, 896, 1044, 2928, 2999, 3822], '34:': [686, 709], '95-106Crossref': [687], '(205)': [690, 1345, 2008, 4186, 4296], '9Bach': [693], 'T.J.': [694], 'Boronat': [695, 1176, 1268, 1931, 2703], 'Campos': [697, 1168, 1266, 1929, 2701], 'Ferrer': [699], 'Vollack': [701], 'K.-U.': [702], '107-122Crossref': [710], '(56)': [713], 'Scholar),': [715, 735, 1192, 1218, 1240, 1277, 1296, 3191, 3269, 3352, 4188, 4298], 'which': [716, 2180, 2900, 3104], 'shared': [718], 'animals': [720], 'fungi': [722], '(10Goldstein': [723], 'J.L.': [724], 'Brown': [725, 3039], 'M.S.': [726], 'Nature.': [727], '1990;': [728], '343:': [729], '425-430Crossref': [730], '(4500)': [733], 'occurs': [736, 770, 1019], 'cytoplasm': [739], 'where': [740, 2560, 2616, 3377], 'sesquiterpenes': [741], '(C15)': [742], 'triterpenes': [744], '(C30)': [745], 'sterols': [748], 'more': [754, 2566, 3842, 3943], 'recently': [755], 'identified': [756, 1431, 2724], '(named': [759], 'first': [762, 1081, 1094, 1440, 1960, 2264, 2393, 3373, 4300], 'committed': [763], 'molecule': [764], 'pathway,': [767, 1866, 2295, 2398], '4-phosphate)': [769], 'also': [775, 2535, 2622, 2683, 2952, 3282, 3416, 4065], 'protozoa,': [778], 'most': [779, 1830], 'bacteria,': [780], 'algae': [782], 'Scholar,11Disch': [815], 'Schwender': [817, 1058, 2198], 'Müller': [819, 1532], 'Rohmer': [823, 912, 957, 1056, 1174, 2196], '333:': [828], '381-388Crossref': [829], '(171)': [832], '12Rohmer': [835], 'Knani': [837], 'Simonin': [839], 'Sutter': [841], 'Sahm': [843, 863, 1150], '1993;': [847], '295:': [848], '517-524Crossref': [849], '(938)': [852], '13Rohmer': [855], 'Seemann': [857, 908, 953], 'Horbach': [859], 'Bringer-Meyer': [861, 1148], 'Am.': [866], 'Chem.': [867, 998], 'Soc.': [868], '1996;': [869, 916, 961, 1312, 4153, 4263], '118:': [870, 3044], '2564-2566Crossref': [871], '(398)': [873], '14Rohmer': [876], 'Prod.': [879], 'Rep.': [880], '16:': [882], '565-574Crossref': [883], '(900)': [886], '15Lichtenthaler': [889], 'Annu.': [891, 1039, 2923], 'Physiol.': [894, 1042, 1060, 1232, 1339, 2002, 2200, 2926, 3042, 3614, 4180, 4290], '50:': [899, 1047, 2931], '47-65Crossref': [900, 1048, 2932], '(1080)': [903, 1051, 2935], '16Schwender': [906], '316:': [917, 962], '73-80Crossref': [918, 963], '(307)': [921, 966], 'This': [924, 1114, 2551, 2680], 'biosynthesis': [934, 1361, 2729, 2868, 3966], 'isoprene,': [936], 'monoterpenes': [937], '(C10),': [938], 'diterpenes': [939], '(C20),': [940], 'plastiquinones,': [942], 'phytol': [944], 'conjugates': [945], 'chlorophylls': [948, 2812], 'tocopherols': [950], '(16Schwender': [951], '17Zeidler': [969], 'J.G.': [970], 'May': [973], 'H.U.': [974], 'F.W.': [976], 'Z.': [977], 'Naturforsch.': [978], '1997;': [979, 1062, 1159, 2202, 3616], '52:': [980], '15-23Crossref': [981], '(133)': [983], '18Eisenreich': [986], 'Schwarz': [988], 'Cartayrade': [990], 'Arigoni': [992], 'Zenk': [994, 1601, 1630, 1665, 1702, 1737], 'Bacher': [996, 1599, 1632, 1667, 1704, 1739], '5:': [1001], '221-233Abstract': [1002], 'Full': [1003], 'Text': [1004], 'PDF': [1005], '(377)': [1008], 'Although': [1011], 'there': [1012, 2155, 2748, 2754, 2848, 3270, 3353], 'evidence': [1014, 2766, 2852], 'some': [1016], 'limited': [1017], 'exchange': [1018], 'between': [1022, 2523, 3965], 'cytoplasmic': [1024, 2188], 'pools': [1027], 'IPP,': [1029, 4036], 'each': [1030, 2502, 3514], 'appears': [1032], 'produce': [1034], 'unique': [1035], '(15Lichtenthaler': [1037, 2921], '19Lichtenthaler': [1054], 'Plant.': [1061, 2201, 3615], '101:': [1063, 2203], '643-652Crossref': [1064, 2204], 'Scholar).Whereas': [1066], 'genes': [1070, 1082, 1422, 3506], 'involved': [1071, 1769, 2256, 4001], 'MVA': [1074, 2189], 'identified,': [1078], 'only': [1079, 1776, 2262, 3297], 'published': [1090], 'involves': [1100], 'transketolase-type': [1102], 'condensation': [1103], 'pyruvate': [1106], 'glyceraldehyde': [1108], '3-phosphate': [1109], 'yield': [1111], '(DXP).': [1113], 'DXP': [1119, 1351, 1450, 1456], '(DXS).': [1121], 'Genes': [1122], 'encoding': [1123], 'DXS': [1124, 1943, 1957, 1976, 2018, 2044, 2064, 2078, 2090, 2287, 2412, 2459, 2472, 2483, 2526, 2621, 2715, 2734, 2769, 2823, 3364, 3393, 4032, 4063, 4250, 4313, 4385, 4421, 4436], 'cloned': [1127], 'characterized': [1129, 4249], 'Escherichia': [1131], 'coli': [1132], '(20Sprenger': [1133], 'G.A.': [1134], 'Schörken': [1135], 'U.': [1136, 1156, 1182, 1208, 1393, 1504, 1607, 1638, 1675, 1710, 1747, 2219], 'Wiegert': [1137], 'Grolle': [1139], 'De': [1141], 'Graaf': [1142], 'A.A.': [1143], 'Taylor': [1144, 2371, 2978, 3801, 3895, 4021], 'S.V.': [1145], 'Begley': [1146], 'T.P.': [1147], 'Proc.': [1152, 1178, 1204, 1389, 1500, 1603, 1671, 1706, 1743, 2215], 'Natl.': [1153, 1179, 1205, 1390, 1501, 1604, 1635, 1672, 1707, 1744, 2216], 'Acad.': [1154, 1180, 1206, 1376, 1391, 1502, 1605, 1636, 1673, 1708, 1745, 2217], 'Sci.': [1155, 1181, 1207, 1377, 1392, 1503, 1606, 1637, 1674, 1709, 1746, 2218], '94:': [1160], '12857-12862Crossref': [1161], '(411)': [1164], 'Scholar,21Lois': [1166], 'L.M.': [1167, 1261, 1924, 2696], 'Putra': [1170], 'S.R.': [1171], 'Danielsen': [1172], 'K.': [1173, 1596], '95:': [1186, 1212, 1508], '2105-2110Crossref': [1187], '(345)': [1190], 'Mentha': [1193], '×': [1194], 'piperita': [1195], '(22Lange': [1196], 'Wildung': [1198], 'M.R.': [1199], 'McCaskill': [1200], '2100-2104Crossref': [1213], '(341)': [1216], 'Capsicum': [1219], 'annuum': [1220], '(23Bouvier': [1221], 'F.': [1222, 1265, 1586, 1619, 1652, 1687, 1742, 1928, 2700], "d'Harlingue": [1223], 'Suire': [1225], 'Backhaus': [1227], 'R.A.': [1228], 'Camara': [1229], '117:': [1234], '1423-1431Crossref': [1235], '(162)': [1238], 'Synechococcus': [1241], 'leopoliensis': [1242], '(24Miller': [1243, 1871, 4329], 'Heuser': [1245, 1550, 1873, 1907, 2652, 4331, 4365], 'Zimmer': [1247, 1552, 1875, 1909, 2654, 4333, 4367], 'FEBS': [1249, 1538, 1554, 1877, 1911, 2656, 2670, 4335, 4369], 'Lett.': [1250, 1539, 1555, 1878, 1912, 2657, 2671, 4336, 4370], '460:': [1252, 1880, 4338], '485-490Crossref': [1253, 1881, 4339], '(36)': [1256, 1884, 4342], 'Scholar),Lycopersicon': [1258], 'esculentum': [1259], '(25Lois': [1260, 1923, 2695], 'Rodrı́guez-Concepción': [1262, 1925, 2697], 'Gallego': [1264, 1927, 2699], '22:': [1273, 1936, 2708], '503-513Crossref': [1274, 1937, 2709], 'Streptomyces': [1278], '(26Kuzuyama': [1279, 2632], 'Takagi': [1281, 1889, 2634, 4347], 'Takahashi': [1283, 1891, 2636, 4349], 'Seto': [1285, 1332, 1498, 1893, 1995, 2638, 4173, 4283, 4351], 'Bacteriol.': [1288, 1896, 2641, 4354], '182:': [1290, 1898, 2643, 4356], '891-897Crossref': [1291, 1899, 2644, 4357], '(118)': [1294, 1902, 2647, 4360], 'thaliana': [1299], '(27Mandel': [1300, 4141, 4251], 'M.A.': [1301, 4142, 4252], 'Feldmann': [1302, 4143, 4253], 'K.A.': [1303, 4144, 4254], 'Herrera-Estrella': [1304, 4145, 4255], 'L.': [1305, 4146, 4256], 'Rocha-Sosa': [1306, 4147, 4257], 'León': [1308, 1336, 1999, 4149, 4177, 4259, 4287], '9:': [1313, 4154, 4264], '649-658Crossref': [1314, 4155, 4265], '(251)': [1317, 4158, 4268], '28Estévez': [1320, 4161, 4271], 'J.M.': [1321, 1984, 4162, 4272], 'Cantero': [1322, 1985, 4163, 4273], 'Romero': [1324, 1987, 4165, 4275], 'Kawaide': [1326, 1989, 4167, 4277], 'Jiménez': [1328, 1991, 4169, 4279], 'L.F.': [1329, 1992, 4170, 4280], 'Kuzuyama': [1330, 1494, 1993, 4171, 4281], 'Kamiya': [1334, 1997, 4175, 4285], 'Y.': [1335, 1998, 4176, 4286], '124:': [1341, 2004, 4182, 4292], '95-103Crossref': [1342, 2005, 4183, 4293], 'utilized': [1357], 'well': [1363, 2783, 4052, 4089], 'thiamin': [1369, 4073, 4098], 'pyridoxol': [1371, 4075, 4100], '(29Julliard': [1372], 'J.H.': [1373, 1386], '(': [1378], 'Paris': [1379], ').': [1380], '1992;': [1381], '314:': [1382], '285-290Google': [1383], '30Julliard': [1385], 'Douce': [1387], '1991;': [1396], '88:': [1397], '2042-2045Crossref': [1398], '(112)': [1401], 'subsequent': [1405], 'be': [1415, 1812, 1838, 2122, 2135, 2275, 2947, 3501, 3586, 3707, 3933], 'specific': [1416, 1442, 2354, 2503, 3929], 'production,': [1419], 'coding': [1423], 'next': [1426], 'four': [1427], 'bacteria': [1434, 1870, 2615, 4328], 'transformation': [1448], '(DXR)': [1458], '31Takahashi': [1492], 'Watanabe': [1496], '9879-9884Crossref': [1509], '(441)': [1512], '32Lange': [1515], 'Arch.': [1519], 'Biophys.': [1521], '365:': [1523], '170-174Crossref': [1524], '(149)': [1527], '33Schwender': [1530], '455:': [1541], '140-144Crossref': [1542], '(137)': [1545], '34Miller': [1548, 1905, 2650, 4363], '481:': [1557, 1914, 2659, 4372], '221-226Crossref': [1558, 1915, 2660, 4373], '(51)': [1561, 1918, 2663, 4376], 'subsequently': [1566], 'converted': [1567], 'into': [1568], '2C-methyl-d-': [1569], 'erythritol': [1570], '2,4-cyclodiphosphate': [1571], 'activities': [1575], 'three': [1577, 2436], 'independent': [1578], 'enzymes': [1579, 1768, 1845, 2489, 2500, 2533, 2574, 2602, 3078, 4319], 'Fig.': [1583], '1': [1584], '(35Rohdich': [1585], 'Wungsintaweekul': [1587, 1620, 1655, 1688, 1723], 'Fellermeier': [1589, 1661, 1698, 1733], 'Sagner': [1591, 1663, 1731], 'Herz': [1593, 1653], 'Kis': [1595], 'Eisenreich': [1597, 1622, 1669, 1694, 1735], 'M.H.': [1602, 1631, 1666, 1703, 1738], '96:': [1611], '11758-11763Crossref': [1612], '(240)': [1615, 1755], '36Rohdich': [1618], 'Richter': [1624], 'G.': [1625], 'Schuhr': [1626, 1659, 1696, 1725], 'Hecht': [1628, 1657, 1727], 'Prot.': [1634], '97:': [1642, 1679, 1714, 1751, 2223], '6451-6456Crossref': [1643], '(98)': [1646], '37Lüttgen': [1649], 'Rohdich': [1651, 1741], '1062-1067Crossref': [1680], '(209)': [1683], '38Rohdich': [1686], 'Lüttgen': [1690], 'Fischer': [1692], 'Schramek': [1700], '8251-8256Crossref': [1715], '(105)': [1718], '39Herz': [1721], 'Luttgen': [1729], '2486-2490Crossref': [1752], 'final': [1759, 1824, 2832, 3577, 4048], 'leading': [1761], 'remain': [1764], 'unknown.Identifying': [1765], 'synthesis': [1772, 1965, 2022, 2744], 'part': [1777, 2403], 'necessary': [1781], 'characterize': [1783], 'complex': [1786], 'fundamental': [1790], 'aspect': [1791], 'identification': [1794, 2237], 'Large': [1802], 'level': [1806, 2299, 2324, 2424, 2445, 2457, 2824, 3464], 'non-limiting': [1809], 'can': [1811, 3705], 'made': [1813], 'little': [1815], 'no': [1817, 2756, 2850, 3355], 'effect': [1818, 2328, 3661, 3687, 4056, 4440], 'on': [1819, 1842, 1952, 2329, 2425, 2688, 2874, 2885, 3662, 4057, 4441], 'quantity': [1821, 2303, 3300, 4061, 4192], 'product;': [1825], 'therefore,': [1826, 2104, 3647], 'fruitful': [1831], 'strategies': [1832], 'altering': [1834, 1956, 2297, 2422], 'content': [1836, 2559, 3226, 3760, 4117], 'will': [1837, 2300, 2325, 2579], 'those': [1839, 3777], 'focus': [1841], '(40Kinney': [1846], 'A.J.': [1847, 2965, 3788, 3882, 4008], '1:': [1853], '173-178Crossref': [1854], '(35)': [1857], 'case': [1862, 2554], 'recent': [1867, 2686], 'studies': [1868, 3086, 3281, 3492, 4136], '26Kuzuyama': [1887, 4345], 'Scholar)': [1920, 1940, 2712, 2937, 3008, 3072, 3206, 3335], 'tomato': [1922, 2689, 3997], 'enzyme.In': [1947], 'article': [1949, 2386], 'report': [1951], 'effects': [1954, 2420, 2593, 3357, 3628, 3712], 'gene': [1961, 1982, 4301], 'plants.': [1967, 2034, 2109, 3959, 3982, 4244, 4389], 'Our': [1968, 2863], 'previous': [1969], 'that,': [1972], 'thaliana,': [1975], 'encoded': [1978], 'CLA1': [1981], '(28Estévez': [1983], 'order': [2012], 'explore': [2014], 'participation': [2016], 'were': [2028, 2387, 2749, 2755, 3271, 3354, 3560, 4121, 4201], 'increased': [2029, 2046, 3228], 'decreased': [2031, 2066], 'Analysis': [2035], 'lines': [2039, 3632, 3916], 'showed': [2040], 'overexpressing': [2043, 3981], 'ABA,': [2055], 'GA.': [2057], 'suppressed': [2061], 'amounts': [2067, 3496, 4071], 'products.': [2072, 2530, 2834], 'fact': [2074, 2837], 'lead': [2080, 2165, 2474, 3396, 4066], 'end': [2086, 2367, 2529, 3303], 'demonstrates': [2088], 'and,': [2103], 'Each': [2110], 'could': [2121, 2134, 3500, 3864, 3932, 3949], 'manipulated;': [2123], 'however,': [2124], 'findings': [2126], 'indicate': [2127], 'output': [2130], 'restricted': [2136, 2567], 'amount': [2139, 2309, 2738, 3286, 3362, 3650], 'plastids.DISCUSSIONBecause': [2147], 'ubiquitous': [2151], 'compounds,': [2154], 'intensive': [2158], 'efforts': [2159], 'understand': [2161], 'All': [2169], 'from': [2173, 2879, 2942, 3411, 3484, 3529, 3643], 'precursor': [2175, 4084], 'DMAPP,': [2179], 'either': [2186, 3603, 3714, 4097], '(19Lichtenthaler': [2194], '59Lange': [2207], 'Rujan': [2209], 'Martin': [2211], '13172-13177Crossref': [2224], '(637)': [2227], 'There': [2230], 'substantial': [2233], 'progress': [2234], 'past': [2248], 'few': [2249], 'years.': [2250], 'However,': [2251, 2883, 4092], 'knowing': [2252], 'it.': [2269], 'Fundamental': [2270], 'aspects': [2271], 'need': [2273], 'addressed': [2276], 'regulatory': [2279, 3108, 3527], 'control': [2281], 'points': [2282], 'If': [2286], 'then': [2296, 2360], 'affect': [2301], 'IPP.': [2305, 2409, 3486, 4091], 'Analogously,': [2306], 'if': [2307, 2411, 2939, 4312], 'isoprenoids,': [2319, 4401], 'an': [2327, 2903, 3437, 4055], 'overall': [2330], 'levels.': [2332, 3695, 3719], 'One': [2333], 'way': [2334], 'define': [2336], 'experimentally': [2337], 'using': [2347], 'reverse': [2348], 'genetics': [2349], 'make': [2351], 'sites': [2355], 'monitoring': [2361], 'corresponding': [2363], '(60Furbank': [2369], 'R.T.': [2370], 'W.C.': [2372], 'Cell.': [2374], '1995;': [2375, 3185, 3263], '7:': [2376], '797-807Crossref': [2377], 'experiments': [2382], 'described': [2383], 'designed': [2388], 'determine': [2390], 'DXS,': [2399, 2447, 3466, 4080], 'Additionally,': [2410], 'limiting,': [2414], 'wanted': [2416, 4309], 'evaluate': [2418], 'seed': [2426], 'germination,': [2427], 'abundance.The': [2432], 'general': [2433, 3379], 'finding': [2434], 'divergent': [2437], 'raising': [2443], 'raised,': [2453], 'when': [2455, 2583, 2747, 3296, 3547, 3850, 3876], 'lowered,': [2461], 'so': [2462], 'isoprenoids.': [2467, 3276, 3423], 'abundance,': [2479], 'propose': [2481], 'It': [2494, 3905], 'likely': [2496, 3584, 3682, 3706], 'other': [2498, 2572, 2599, 2943, 3275, 3356, 3442, 3667, 3698, 3848], 'co-limiting': [2499], 'present': [2506], 'further': [2513, 2581], 'downstream,': [2514], 'did': [2517], 'observe': [2519, 3866], 'linear': [2521], 'relationship': [2522], 'Additional': [2531], 'would': [2534], 'explain': [2536], 'differences': [2538, 2826, 3559, 3581, 3677, 3701, 4068], 'observed': [2539, 3561, 3591, 3978, 4106, 4202, 4391], 'relative': [2542, 2592, 3299], 'increases': [2543, 2561, 2750, 2757, 2761, 4404], 'among': [2544], 'monitored': [2547], 'work.': [2550], 'chlorophyll': [2556], 'carotenoid': [2558, 2719, 2728, 2743, 3225], 'than': [2568], 'others.': [2569], 'identify': [2571], 'require': [2580], 'analyses': [2582], 'complete': [2585], 'enzymatic': [2586], 'known': [2589], 'changing': [2595, 3360, 3648], 'evaluated.': [2605], 'Recently,': [2606], 'intensively': [2612, 2846], 'studied': [2613], 'it': [2617, 2940, 3405, 4093, 4325], 'was': [2618, 2716, 2735, 3227, 3305, 3387, 3859, 3989, 4314], 'enzyme,': [2627, 4000], 'DXR': [2629], '52Harker': [2666], '448:': [2673], '115-119Crossref': [2674], '(132)': [2677], 'conclusion': [2681], 'supported': [2684], 'fruit': [2690], 'ripening.': [2691], 'Lois': [2692], 'et': [2693], 'al.': [2694], 'over': [2721], 'previously': [2723], '(PSY1).': [2730], 'They': [2731], 'reasoned': [2732], 'available': [2741], 'because': [2745, 3596, 4076, 4112], 'even': [2746], 'inPSY1': [2751], 'transcript': [2752], 'carotenoids': [2759], 'without': [2760, 3440], 'DXS.': [2763, 4414], 'accumulated': [2765], 'indicates': [2767], 'bacteria.In': [2786], 'analyzed': [2790], 'synthesized': [2794, 2858], 'at': [2795, 2870, 2954], 'very': [2796, 3774], 'low': [2797], 'hormones,': [2801, 3103], 'large': [2808, 3090], 'quantities': [2809], 'carotenoids.': [2814], 'cases': [2817], 'moderate': [2819, 3390], 'change': [2820, 3472], 'Despite': [2835], 'GA': [2843, 2867, 3010, 3594], 'studied,': [2847], 'direct': [2851, 3660], 'actually': [2857], 'via': [2859], 'data': [2864], 'depends,': [2869], 'least': [2871], 'part,': [2873, 3209], 'comes': [2878, 2941], 'based': [2884], 'expression': [2887, 3994], 'GA4': [2890], 'gene,': [2891], 'cla1-1': [2893, 4139], 'mutant': [2894, 4140], 'seems': [2895, 3971], 'contain': [2897], 'GA,': [2899], 'suggests': [2901], 'additional': [2904, 3106, 3951], 'source': [2905], 'exists.': [2908], 'Whether': [2909], 'result': [2914, 3601], 'import': [2917], 'cytosolic': [2919], 'sources': [2944], 'remains': [2945], 'established.': [2948], 'Other': [2949], 'looked': [2953], 'increasing': [2955, 3119], 'decreasing': [2957, 3441], 'ABA': [2963, 3718, 3720, 3759, 3780, 3843, 3912, 3954, 3970, 3976, 4004], '(58Thompson': [2964, 3787, 3881, 4007], 'Jackson': [2966, 3789, 3883, 4009], 'A.C.': [2967, 3790, 3884, 4010], 'Symonds': [2968, 3791, 3885, 4011], 'R.C.': [2969, 3792, 3886, 4012], 'Mulholland': [2970, 3793, 3887, 4013], 'B.J.': [2971, 3794, 3888, 4014], 'Dadswell': [2972, 3795, 3889, 4015], 'A.R.': [2973, 3796, 3890, 4016], 'Blake': [2974, 3797, 3891, 4017], 'P.S.': [2975, 3798, 3892, 4018], 'Burbidge': [2976, 3799, 3893, 4019], 'I.B.': [2979, 3802, 3896, 4022], '23:': [2983, 3806, 3900, 4026], '363-374Crossref': [2984, 3807, 3901, 4027], '61Frey': [2988, 3811], 'Audran': [2990, 3813], 'Marin': [2992, 3815], 'Sotta': [2994, 3817], 'Marion-Poll': [2996, 3819], '39:': [3002, 3825], '1267-1274Crossref': [3003, 3826], '(111)': [3006, 3829], '(62Eriksson': [3011], 'M.E.': [3012], 'Israelsson': [3013], 'Olsson': [3015], 'O.': [3016], 'Moritz': [3017], '784-788Crossref': [3023], '(393)': [3026], '63Huang': [3029], 'S.S.': [3030], 'Raman': [3031], 'A.S.': [3032], 'Ream': [3033], 'J.E.': [3034], 'Fujiwara': [3035], 'Cerny': [3037], 'R.E.': [3038], 'S.M.': [3040], '773-781Crossref': [3045], '(179)': [3048], '64Coles': [3051], 'J.P.': [3052], 'Phillips': [3053], 'A.L.': [3054], 'Croker': [3055], 'S.J.': [3056], 'Garcı́a-Lepe': [3057], 'Lewis': [3059], 'M.J.': [3060], 'Hedden': [3061, 3177, 3255], '17:': [3066], '547-556Crossref': [3067], '(245)': [3070], 'modulating': [3074], 'individual': [3081, 3438, 3498], 'post-IPP': [3082, 3509, 3517, 3784], 'pathways.': [3084], 'These': [3085, 3487, 3580, 3771, 3983], 'obtained': [3088, 3778], 'relatively': [3089], 'hormone': [3093, 3600, 3694], 'phenotypes': [3096, 3546, 3607, 3849, 3923, 4107, 4199], 'complementing': [3097], 'proposed': [3099, 3963], 'demonstrate': [3105, 3512], 'key': [3107], 'pathways.Much': [3113], 'research': [3114], 'devoted': [3117], 'α-carotene,': [3125], '(3Römer': [3127, 3312], '65Shewmaker': [3151], 'C.K.': [3152, 3230], 'Sheehy': [3153, 3231], 'J.A.': [3154, 3232], 'Daley': [3155, 3233], 'Colburn': [3157, 3235], 'Ke': [3159, 3237], 'D.Y.': [3160, 3238], '20:': [3164, 3242], '401-412Crossref': [3165, 3243], '66Fray': [3169, 3247], 'R.G.': [3170, 3248], 'Wallace': [3171, 3249], 'Valero': [3175, 3253], 'Grierson': [3181, 3259], '8:': [3186, 3264], '693-701Crossref': [3187, 3265], '(296)': [3189, 3267], '(2Shintani': [3194, 3340], 'due,': [3207], 'importance': [3212], 'precursors': [3217], 'vitamins': [3219, 4194], 'needed': [3220], 'mammals.': [3222], 'When': [3223], 'total': [3224], '(65Shewmaker': [3229], 'concomitant': [3272], 'decreases': [3273, 4406], 'support': [3283], 'contrast,': [3295], 'changed': [3306], 'α-carotene': [3309], 'γ-tocopherol': [3337], 'noted.': [3358], 'By': [3359, 4245], 'thus': [3366], 'reporting': [3371], 'instance': [3374], 'increase': [3380, 3436, 3447, 3458], 'decrease': [3382, 3460], 'multiple': [3384], 'observed.': [3388], '(38–172x0025;)': [3395], 'tested,': [3404], 'apparent': [3407], 'role': [3426, 3724], 'availability': [3429, 3665], 'implies': [3433], 'requires': [3444], 'concurrent': [3446], 'production.Even': [3450], 'though': [3451], 'according': [3461], 'do': [3470, 3844], 'equally': [3473], 'showing': [3474], 'complexity': [3476], 'diverge': [3483], 'results,': [3488], 'together': [3489], 'mentioned': [3493], 'above': [3494], 'wherein': [3495], 'modulated': [3502], 'through': [3503], 'manipulation': [3504], 'pathways,': [3511], 'own': [3522], 'set': [3523], 'steps.Aside': [3528], 'measured': [3531], 'content,': [3535], 'DXS-overexpressing': [3537, 3765], '-suppressed': [3539], 'close': [3543], 'normal': [3545, 3853, 3879], 'grown': [3548, 3851, 3877], 'medium': [3551], 'soil': [3554], 'under': [3555, 3852, 3878], 'optimal': [3556], 'Significant': [3558], 'rates': [3565, 3680, 3704], '8-': [3568], '26-day-old': [3570], 'but': [3573, 4045], 'size.': [3579], 'due': [3587, 3683], 'solely': [3588], 'dwarf': [3604], 'giant': [3606], '(67Ross': [3608], 'J.J.': [3609], 'Murfet': [3610], 'I.C.': [3611], 'Reid': [3612], 'J.B.': [3613], '100:': [3617], '550-560Crossref': [3618], 'possible': [3622, 3907], 'explanation': [3623], 'rate': [3627], 'receives': [3639], 'substrates': [3641], 'directly': [3642, 3708], 'Calvin': [3645], 'cycle;': [3646], 'might': [3657], 'carbon': [3664, 3691], 'cell.': [3671], 'Therefore,': [3672], 'hypothesized': [3674], 'pleiotropic': [3686], 'metabolism': [3692], 'On': [3696], 'hand,': [3699], 'correlated': [3709], 'raised': [3715], 'lowered': [3717], 'plays': [3721], 'major': [3723], 'setting': [3726], 'maintaining': [3728], 'dormancy': [3729], 'seeds': [3731], '(56Koornneef': [3732], 'Karssen': [3734], 'C.M.': [3735], 'Meyerowitz': [3736], 'E.M.': [3737], 'Somerville': [3738], 'C.R.': [3739], 'Seed': [3740], 'Dormancy': [3741], 'Germination.': [3743], 'Cold': [3744, 3748], 'Spring': [3745, 3749], 'Harbor': [3746], 'Laboratory,': [3747], 'Harbor,': [3750], 'NY1994:': [3751], '313-334Google': [3752], 'DXS-suppressed': [3755], 'less': [3758], 'germinated': [3761], 'rapidly,': [3762], 'whereas': [3763], 'poor': [3768], 'similar': [3775, 3986], 'mutants': [3781], 'addition': [3833], 'rates,': [3837, 4044], 'containing': [3840, 4128], '4-fold': [3841], 'display': [3846, 3936], 'any': [3847], 'contrast': [3856], 'what': [3858, 3988], 'reported': [3860], 'tomato,': [3862], 'overguttation': [3867], 'chlorosis': [3869], 'leaves': [3872], 'conditions': [3880], 'sufficient': [3919], 'generate': [3921], 'condition': [3931], 'phenotypes.': [3938], 'We': [3939, 4379, 4390], 'believe': [3940], 'analysis': [3945], 'provide': [3950], 'information': [3952], 'about': [3953], 'function': [3957], 'For': [3960], 'example,': [3961], 'catabolism': [3968], 'insufficient': [3972], 'prevent': [3974], 'increments': [3977], 'ectopic': [3993], '9-cis-epoxycarotenoid': [3998], 'dioxygenase': [3999], 'Altering': [4031], 'hence': [4035], 'manifested': [4037], 'itself': [4038], 'phenotypically': [4039], 'size,': [4050], 'having': [4054, 4246], 'rates.Varying': [4059], 'may': [4064], 'DXP,': [4081], 'unlikely': [4095], 'deficiency': [4101], 'gives': [4102], 'rise': [4103], 'measurements': [4114], 'seedling': [4119], 'size': [4120], 'performed': [4122], 'presence': [4125], 'media': [4127], 'vitamin': [4129], 'supplements.': [4130], 'As': [4131], 'suggested': [4132], 'cannot': [4195], 'account': [4196], 'plants.Finally,': [4206], 'useful': [4211], 'medical,': [4213], 'nutritional,': [4214], 'applications': [4217], 'ability': [4220], 'manipulate': [4222], 'successfully': [4223], 'metabolic': [4224], 'continues': [4228], 'improve,': [4230], 'becoming': [4233], 'prime': [4235], 'target': [4236], 'commercially': [4241], 'viable': [4242], 'isolated': [4247], 'know': [4311], 'tested': [4380], 'idea': [4382], 'manipulating': [4384], 'followed': [4410], 'Also,': [4432], 'exert': [4438], 'isopren': [4442]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2083538904', 'counts_by_year': [{'year': 2024, 'cited_by_count': 25}, {'year': 2023, 'cited_by_count': 30}, {'year': 2022, 'cited_by_count': 33}, {'year': 2021, 'cited_by_count': 36}, {'year': 2020, 'cited_by_count': 29}, {'year': 2019, 'cited_by_count': 31}, {'year': 2018, 'cited_by_count': 27}, {'year': 2017, 'cited_by_count': 32}, {'year': 2016, 'cited_by_count': 30}, {'year': 2015, 'cited_by_count': 41}, {'year': 2014, 'cited_by_count': 30}, {'year': 2013, 'cited_by_count': 37}, {'year': 2012, 'cited_by_count': 31}], 'updated_date': '2024-12-18T17:42:09.717274', 'created_date': '2016-06-24'}