Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2083458143', 'doi': 'https://doi.org/10.1046/j.1523-1747.1999.00629.x', 'title': 'IL-4 Inhibits the Migration of Human Langerhans Cells through the Downregulation of TNF Receptor II Expression', 'display_name': 'IL-4 Inhibits the Migration of Human Langerhans Cells through the Downregulation of TNF Receptor II Expression', 'publication_year': 1999, 'publication_date': '1999-10-01', 'ids': {'openalex': 'https://openalex.org/W2083458143', 'doi': 'https://doi.org/10.1046/j.1523-1747.1999.00629.x', 'mag': '2083458143', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10504438'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1046/j.1523-1747.1999.00629.x', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15406141/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.jidonline.org/article/S0022202X15406141/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052932989', 'display_name': 'Kaoru Takayama', 'orcid': 'https://orcid.org/0000-0001-9204-6636'}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kaoru Takayama', 'raw_affiliation_strings': ['Department of Dermatology, Tokyo Medical and Dental University, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Tokyo Medical and Dental University, Japan.', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000565136', 'display_name': 'Hiroo Yokozeki', 'orcid': 'https://orcid.org/0000-0002-5773-9485'}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroo Yokozeki', 'raw_affiliation_strings': ['Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108480557', 'display_name': 'Mehran Ghoreishi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mehran Ghoreishi', 'raw_affiliation_strings': ['Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037667479', 'display_name': 'Takahiro Satoh', 'orcid': 'https://orcid.org/0000-0002-2244-6332'}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takahiro Satoh', 'raw_affiliation_strings': ['Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033368470', 'display_name': 'Tadashi Umeda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tadashi Umeda', 'raw_affiliation_strings': ['Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049548990', 'display_name': 'Kiyoshi Nishioka', 'orcid': 'https://orcid.org/0000-0002-8577-7825'}, 'institutions': [{'id': 'https://openalex.org/I125602781', 'display_name': 'Tokyo Medical and Dental University', 'ror': 'https://ror.org/051k3eh31', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I125602781']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kiyoshi Nishioka', 'raw_affiliation_strings': ['Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Departments of Dermatology, Tokyo Medical and Dental University, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I125602781']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111461056', 'display_name': 'Ichiro Katayama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43777268', 'display_name': 'Nagasaki University', 'ror': 'https://ror.org/058h74p94', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I43777268']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ichiro Katayama', 'raw_affiliation_strings': ['Nagasaki University, School of Medicine, Yushima, Bunkyo-ku, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Nagasaki University, School of Medicine, Yushima, Bunkyo-ku, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I43777268']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3400, 'currency': 'USD', 'value_usd': 3400, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.485, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 42, 'citation_normalized_percentile': {'value': 0.733748, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '113', 'issue': '4', 'first_page': '541', 'last_page': '546'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11033', 'display_name': 'Contact Dermatitis and Allergies', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2708', 'display_name': 'Dermatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/epidermis', 'display_name': 'Epidermis (zoology)', 'score': 0.46998253}], 'concepts': [{'id': 'https://openalex.org/C2778379841', 'wikidata': 'https://www.wikidata.org/wiki/Q1623344', 'display_name': 'Langerhans cell', 'level': 3, 'score': 0.73399925}, {'id': 'https://openalex.org/C17991360', 'wikidata': 'https://www.wikidata.org/wiki/Q21173843', 'display_name': 'Tumor necrosis factor alpha', 'level': 2, 'score': 0.5654614}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.504049}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.48010018}, {'id': 'https://openalex.org/C2776458125', 'wikidata': 'https://www.wikidata.org/wiki/Q1827343', 'display_name': 'Epidermis (zoology)', 'level': 2, 'score': 0.46998253}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.46650997}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40662336}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.39609692}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3792659}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.33953887}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.21956965}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D018124', 'descriptor_name': 'Receptors, Tumor Necrosis Factor', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015703', 'descriptor_name': 'Antigens, CD', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007375', 'descriptor_name': 'Interleukin-1', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007375', 'descriptor_name': 'Interleukin-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018124', 'descriptor_name': 'Receptors, Tumor Necrosis Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047889', 'descriptor_name': 'Receptors, Tumor Necrosis Factor, Type II', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1046/j.1523-1747.1999.00629.x', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15406141/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10504438', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1046/j.1523-1747.1999.00629.x', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15406141/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W126653784', 'https://openalex.org/W131233735', 'https://openalex.org/W1510470032', 'https://openalex.org/W1543727885', 'https://openalex.org/W1552770707', 'https://openalex.org/W1555595118', 'https://openalex.org/W1815911511', 'https://openalex.org/W1894910697', 'https://openalex.org/W1976614186', 'https://openalex.org/W1982300086', 'https://openalex.org/W1998059118', 'https://openalex.org/W1999029709', 'https://openalex.org/W2007321497', 'https://openalex.org/W2008330541', 'https://openalex.org/W2020821867', 'https://openalex.org/W2022556924', 'https://openalex.org/W2024352457', 'https://openalex.org/W2024355558', 'https://openalex.org/W2029357865', 'https://openalex.org/W2030154667', 'https://openalex.org/W2038394009', 'https://openalex.org/W2057656322', 'https://openalex.org/W2060069814', 'https://openalex.org/W2077616126', 'https://openalex.org/W2086268791', 'https://openalex.org/W2092551238', 'https://openalex.org/W2101186488', 'https://openalex.org/W2103685679', 'https://openalex.org/W2131761283', 'https://openalex.org/W2132762158', 'https://openalex.org/W2200533445', 'https://openalex.org/W2402323954', 'https://openalex.org/W2419622634', 'https://openalex.org/W4239357337', 'https://openalex.org/W4245214519', 'https://openalex.org/W4252817778'], 'related_works': ['https://openalex.org/W930951134', 'https://openalex.org/W2262917748', 'https://openalex.org/W2119200515', 'https://openalex.org/W2098543865', 'https://openalex.org/W2090758155', 'https://openalex.org/W2088425305', 'https://openalex.org/W2010747958', 'https://openalex.org/W1977028102', 'https://openalex.org/W1831946729', 'https://openalex.org/W1511166986'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2083458143', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-09T14:56:05.877906', 'created_date': '2016-06-24'}