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'model': [106, 140, 215], 'built': [108], 'successfully': [110], 'simulate': [111, 220], 'profile': [114], 'AMIO': [116, 132, 149, 167, 181, 204], 'MDEA,': [118], 'particularly': [119], 'their': [120], 'accumulation': [121, 227], 'plasma': [123, 235], 'liver': [125, 237], 'after': [126], 'long-term': [128], 'treatment.': [129], 'clinical': [131, 246], 'DDIs': [133, 247], 'were': [134, 190, 211], 'predicted': [135], 'verified': [138], 'with': [141, 216], 'incorporation': [142], 'cytochrome': [144], 'P450': [145], 'both': [148, 166], 'MDEA.': [151], 'closest': [153], 'prediction': [154], 'obtained': [156], 'for': [157, 172, 193], 'CYP3A': [158], '(simvastatin)': [159], 'DDI': [160, 175, 196, 221], 'when': [161, 176, 197], 'competitive': [163, 178, 184, 199, 207], 'MDEA': [169, 189, 210], 'considered,': [171], 'CYP2D6': [173], '(dextromethorphan)': [174], 'plus': [185, 200], 'time-dependent': [186, 201], 'incorporated,': [191], 'CYP2C9': [194], '(warfarin)': [195], 'considered.': [212], 'ability': [218], 'considering': [223], 'dynamic': [224], 'change': [225], 'inhibitor': [229], '(parent': [230], 'metabolite)': [232], 'concentration': [233], 'provides': [238], 'advantages': [239], 'understanding': [241], 'possible': [243], 'mechanism': [244], 'metabolites.': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2082922601', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 8}], 'updated_date': '2024-12-24T14:36:57.024688', 'created_date': '2016-06-24'}