Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2082865936', 'doi': 'https://doi.org/10.1016/j.bbrc.2005.01.156', 'title': 'The protein kinase inhibitor, staurosporine, inhibits L-type Ca2+ current in rabbit atrial myocytes', 'display_name': 'The protein kinase inhibitor, staurosporine, inhibits L-type Ca2+ current in rabbit atrial myocytes', 'publication_year': 2005, 'publication_date': '2005-02-11', 'ids': {'openalex': 'https://openalex.org/W2082865936', 'doi': 'https://doi.org/10.1016/j.bbrc.2005.01.156', 'mag': '2082865936', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15737619'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2005.01.156', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110179610', 'display_name': 'Jae Hong Ko', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jae Hong Ko', 'raw_affiliation_strings': ['Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091654903', 'display_name': 'Won Sun Park', 'orcid': 'https://orcid.org/0000-0001-5868-3797'}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Won Sun Park', 'raw_affiliation_strings': ['Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.', 'institution_ids': ['https://openalex.org/I139264467']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5108205198', 'display_name': 'Yung E. Earm', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I139264467', 'display_name': 'Seoul National University', 'ror': 'https://ror.org/04h9pn542', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I139264467']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Yung E. Earm', 'raw_affiliation_strings': ['Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and National Research Laboratory for Cellular Signaling, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea.', 'institution_ids': ['https://openalex.org/I139264467']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.363, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.623697, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '329', 'issue': '2', 'first_page': '531', 'last_page': '537'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11601', 'display_name': 'Neuroscience and Neural Engineering', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chelerythrine', 'display_name': 'Chelerythrine', 'score': 0.90903044}, {'id': 'https://openalex.org/keywords/staurosporine', 'display_name': 'Staurosporine', 'score': 0.88925654}, {'id': 'https://openalex.org/keywords/bisindolylmaleimide', 'display_name': 'Bisindolylmaleimide', 'score': 0.43181255}], 'concepts': [{'id': 'https://openalex.org/C2776108454', 'wikidata': 'https://www.wikidata.org/wiki/Q5089853', 'display_name': 'Chelerythrine', 'level': 4, 'score': 0.90903044}, {'id': 'https://openalex.org/C2779084600', 'wikidata': 'https://www.wikidata.org/wiki/Q5957181', 'display_name': 'Staurosporine', 'level': 4, 'score': 0.88925654}, {'id': 'https://openalex.org/C195794163', 'wikidata': 'https://www.wikidata.org/wiki/Q420877', 'display_name': 'Protein kinase C', 'level': 3, 'score': 0.7719389}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6118443}, {'id': 'https://openalex.org/C147944092', 'wikidata': 'https://www.wikidata.org/wiki/Q176366', 'display_name': 'Patch clamp', 'level': 3, 'score': 0.5218931}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.5038888}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.4830516}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.46193233}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.45219454}, {'id': 'https://openalex.org/C2777314051', 'wikidata': 'https://www.wikidata.org/wiki/Q27075304', 'display_name': 'Bisindolylmaleimide', 'level': 4, 'score': 0.43181255}, {'id': 'https://openalex.org/C207200792', 'wikidata': 'https://www.wikidata.org/wiki/Q428914', 'display_name': 'Myocyte', 'level': 2, 'score': 0.4137302}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3880275}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.37457263}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.25546175}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.18644097}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.16744336}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.1104539}], 'mesh': [{'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020746', 'descriptor_name': 'Calcium Channels, L-Type', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D020746', 'descriptor_name': 'Calcium Channels, L-Type', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015640', 'descriptor_name': 'Ion Channel Gating', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D008564', 'descriptor_name': 'Membrane Potentials', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D019311', 'descriptor_name': 'Staurosporine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016275', 'descriptor_name': 'Atrial Function', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D016275', 'descriptor_name': 'Atrial Function', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020746', 'descriptor_name': 'Calcium Channels, L-Type', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006325', 'descriptor_name': 'Heart Atria', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D006325', 'descriptor_name': 'Heart Atria', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006325', 'descriptor_name': 'Heart Atria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015640', 'descriptor_name': 'Ion Channel Gating', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015640', 'descriptor_name': 'Ion Channel Gating', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008564', 'descriptor_name': 'Membrane Potentials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008564', 'descriptor_name': 'Membrane Potentials', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D032383', 'descriptor_name': 'Myocytes, Cardiac', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D047428', 'descriptor_name': 'Protein Kinase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019311', 'descriptor_name': 'Staurosporine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2005.01.156', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15737619', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.51, 'display_name': 'Clean water and sanitation'}], 'grants': [{'funder': 'https://openalex.org/F4320322030', 'funder_display_name': 'Ministry of Science, ICT and Future Planning', 'award_id': None}, {'funder': 'https://openalex.org/F4320331163', 'funder_display_name': 'Ministry of Education, Kenya', 'award_id': None}, {'funder': 'https://openalex.org/F4320337628', 'funder_display_name': 'U.S. Naval Research Laboratory', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 32, 'referenced_works': ['https://openalex.org/W1501435613', 'https://openalex.org/W1576671418', 'https://openalex.org/W1589866689', 'https://openalex.org/W1965893204', 'https://openalex.org/W1986555849', 'https://openalex.org/W2000060432', 'https://openalex.org/W2000767760', 'https://openalex.org/W2004599322', 'https://openalex.org/W2009292667', 'https://openalex.org/W2009667219', 'https://openalex.org/W2039951349', 'https://openalex.org/W2043330848', 'https://openalex.org/W2046606366', 'https://openalex.org/W2050338578', 'https://openalex.org/W2055377397', 'https://openalex.org/W2059022983', 'https://openalex.org/W2064226629', 'https://openalex.org/W2076660235', 'https://openalex.org/W2079509424', 'https://openalex.org/W2084713622', 'https://openalex.org/W2085992470', 'https://openalex.org/W2092157326', 'https://openalex.org/W2101822309', 'https://openalex.org/W2114940281', 'https://openalex.org/W2124614707', 'https://openalex.org/W2126308098', 'https://openalex.org/W2134921936', 'https://openalex.org/W2137850606', 'https://openalex.org/W2226437153', 'https://openalex.org/W2285160624', 'https://openalex.org/W2398972980', 'https://openalex.org/W4247231961'], 'related_works': ['https://openalex.org/W2079613256', 'https://openalex.org/W2073239454', 'https://openalex.org/W2051176010', 'https://openalex.org/W2041797033', 'https://openalex.org/W2028212721', 'https://openalex.org/W2003274858', 'https://openalex.org/W1984443415', 'https://openalex.org/W1976045324', 'https://openalex.org/W1972648199', 'https://openalex.org/W1481175'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2082865936', 'counts_by_year': [{'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-16T05:33:11.531071', 'created_date': '2016-06-24'}