Title: All-TRANS-retinoic acid modulates the radiosensitivity of proliferating cells
Abstract: International Journal of CancerVolume 70, Issue 4 p. 488-490 Special ReportFree Access All-TRANS-retinoic acid modulates the radiosensitivity of proliferating cells Ulrike Schiller, Ulrike Schiller Section of Radiobiology and Molecular Environmental Research, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorWolfgang Hoffmann, Wolfgang Hoffmann Department of Radiotherapy, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorMichael Bamberg, Michael Bamberg Department of Radiotherapy, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorH. Peter Rodemann, Corresponding Author H. Peter Rodemann Section of Radiobiology and Molecular Environmental Research, Eberhard-Karls-University, Tübingen, GermanySection of Radiobiology and Molecular Environmental Research, Department of Radiotherapy. Eberhard-Karls-University, Tübingen, Röntgenweg 11, 72076 Tübingen, Germany. Fax: 49 7071 29 5900Search for more papers by this author Ulrike Schiller, Ulrike Schiller Section of Radiobiology and Molecular Environmental Research, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorWolfgang Hoffmann, Wolfgang Hoffmann Department of Radiotherapy, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorMichael Bamberg, Michael Bamberg Department of Radiotherapy, Eberhard-Karls-University, Tübingen, GermanySearch for more papers by this authorH. Peter Rodemann, Corresponding Author H. Peter Rodemann Section of Radiobiology and Molecular Environmental Research, Eberhard-Karls-University, Tübingen, GermanySection of Radiobiology and Molecular Environmental Research, Department of Radiotherapy. Eberhard-Karls-University, Tübingen, Röntgenweg 11, 72076 Tübingen, Germany. Fax: 49 7071 29 5900Search for more papers by this author First published: 06 December 1998 https://doi.org/10.1002/(SICI)1097-0215(19970207)70:4<488::AID-IJC22>3.0.CO;2-ACitations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. References Alpen, E. L., Radiation biophysics, Prentice-Hall, Englewood Cliffs, NJ (1990). Bayreuther, K., Rodemann, H. P., Hommel, R., Dittmann, K., Albiez, M. and Francz, P. I., Human skin fibroblasts in vitro differentiate along a terminal cell lineage. Proc. nat. Acad. Sci. (Wash.), 85, 5112– 5116 (1988). DeLaney, T. F., Afredi, N., Taghian, A. G., Sanders, D. A., Fuleihan, N. S., Faller, D. V. and Noguera, C. R., 13-cis retinoic acid with α-2a-interferon enhances radiation cytotoxicity in head and neck squamous cell carcinoma in vitro. Cancer Res., 56, 2277– 2280 (1996). Dittmann, K., Loffler, H., Bamberg, M. and Rodemann, H. R., Bowman-Birk proteinase inhibitor (BBI) modulates radiosensitivity and radiation-induced differentiation of human fibroblasts in culture. Radiother. Oncol., 34, 137– 143 (1995). Gudas, L. J.., Sporn, M. B. and Roberts, A. B., Cellular biology and biochemistry of retinoids. In: M. B. Sporn, A. B. Roberts and D. S. Goodman (eds.), Retinoids, pp. 443– 520, New York, CRC Press (1994). Hoffmann, W., Bamberg, M. and Rodemann, H. P., Antiproliferative effects of ionizing radiation, all-trans-retinoic acid and interferon-α on cultured human squamous cell carcinomas. Radiat. Oncol. Invest, 2, 12– 19 (1994). Johansen, I., Bentzen, S. M., Overgaard, J. and Overgaard, M., Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy. Int. J. Radial Biol., 66, 407– 412 (1994). Rodemann, H. P., Differential degradation of intracellular proteins in human skin fibroblasts of mitotic and mitomycin-C (MMC)-induced postmitotic differentiation states. Differentiation, 42, 37– 43 (1989). Rutz, H. P. and Little, J. B., Modification of radiosensitivity and recovery from x-ray damage in vitro by retinoic acid. J. Radial Oncol. Biol Phys., 16, 1285– 1288 (1989). Schiller, U., Hoffmann, W., Mayer, C., Ulrich, W., Bamberg, M. and Rodemann, H. P., All-trans-retinoic acid modulates the radiosensitivity and differentiation of normal and tumour cells in vitro. Ann. Oncol., 5, 1– 3 (1994). M. I. Sherman (ed.), Retinoids and cell differentiation. Boca Raton, FL, CRC Press (1986). Citing Literature Volume70, Issue47 February 1997Pages 488-490 ReferencesRelatedInformation