Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2082312462', 'doi': 'https://doi.org/10.1046/j.1432-0436.2001.680411.x', 'title': 'Brain from bone: Efficient “meta-differentiation” of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent', 'display_name': 'Brain from bone: Efficient “meta-differentiation” of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent', 'publication_year': 2001, 'publication_date': '2001-10-01', 'ids': {'openalex': 'https://openalex.org/W2082312462', 'doi': 'https://doi.org/10.1046/j.1432-0436.2001.680411.x', 'mag': '2082312462', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11776476'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1432-0436.2001.680411.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53475899', 'display_name': 'Differentiation', 'issn_l': '0301-4681', 'issn': ['0301-4681', '1432-0436'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027660737', 'display_name': 'Jun Kohyama', 'orcid': 'https://orcid.org/0000-0001-8168-8588'}, 'institutions': [{'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Jun Kohyama', 'raw_affiliation_strings': ['Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}, {'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007193204', 'display_name': 'Hitoshi Abe', 'orcid': 'https://orcid.org/0000-0001-6970-3642'}, 'institutions': [{'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Hitoshi Abe', 'raw_affiliation_strings': ['Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019166922', 'display_name': 'Takuya Shimazaki', 'orcid': 'https://orcid.org/0000-0003-1019-8914'}, 'institutions': [{'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Takuya Shimazaki', 'raw_affiliation_strings': ['Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Division of Neuroanatomy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}, {'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Division of Neuroanatomy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011071073', 'display_name': 'Amane Koizumi', 'orcid': 'https://orcid.org/0000-0003-1177-0185'}, 'institutions': [{'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Amane Koizumi', 'raw_affiliation_strings': ['Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032557530', 'display_name': 'Kinichi Nakashima', 'orcid': 'https://orcid.org/0000-0001-5901-9628'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kinichi Nakashima', 'raw_affiliation_strings': ['Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University 2-2-1, Honjo, Kumamoto 860-0811, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University 2-2-1, Honjo, Kumamoto 860-0811, Japan', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073581014', 'display_name': 'Satoshi Gojo', 'orcid': 'https://orcid.org/0000-0001-8115-7816'}, 'institutions': [{'id': 'https://openalex.org/I8588240', 'display_name': 'Saitama Medical University', 'ror': 'https://ror.org/04zb31v77', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I8588240']}, {'id': 'https://openalex.org/I4210158720', 'display_name': 'Social Insurance Saitama Chuo Hospital', 'ror': 'https://ror.org/04vqzd428', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210132540', 'https://openalex.org/I4210158720']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Satoshi Gojo', 'raw_affiliation_strings': ['Department of Cardiac Surgery, Saitama Medical Center, Kawagoe, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiac Surgery, Saitama Medical Center, Kawagoe, Japan', 'institution_ids': ['https://openalex.org/I8588240', 'https://openalex.org/I4210158720']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015481457', 'display_name': 'Tetsuya Taga', 'orcid': 'https://orcid.org/0000-0002-1625-0122'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsuya Taga', 'raw_affiliation_strings': ['Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University 2-2-1, Honjo, Kumamoto 860-0811, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Fate Modulation, Institute of Molecular Embryology and Genetics, Kumamoto University 2-2-1, Honjo, Kumamoto 860-0811, Japan', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035479034', 'display_name': 'Hideyuki Okano', 'orcid': 'https://orcid.org/0000-0001-7482-5935'}, 'institutions': [{'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}, {'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Hideyuki Okano', 'raw_affiliation_strings': ['Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Division of Neuroanatomy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}, {'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Division of Neuroanatomy, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110412652', 'display_name': 'Jun-ichi Hata', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Jun-ichi Hata', 'raw_affiliation_strings': ['Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5027421629', 'display_name': 'Akihiro Umezawa', 'orcid': 'https://orcid.org/0000-0002-0485-6653'}, 'institutions': [{'id': 'https://openalex.org/I38260057', 'display_name': 'In-Q-Tel', 'ror': 'https://ror.org/02qp5k481', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I38260057']}, {'id': 'https://openalex.org/I4210107168', 'display_name': 'Keio University Hospital', 'ror': 'https://ror.org/01k8ej563', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210107168']}], 'countries': ['JP', 'US'], 'is_corresponding': True, 'raw_author_name': 'Akihiro Umezawa', 'raw_affiliation_strings': ['Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290'], 'affiliations': [{'raw_affiliation_string': 'Tel: +\u200981 3 5363 3764, Fax: +\u200981 3 3353 3290', 'institution_ids': ['https://openalex.org/I38260057']}, {'raw_affiliation_string': 'Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan', 'institution_ids': ['https://openalex.org/I4210107168']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5027421629'], 'corresponding_institution_ids': ['https://openalex.org/I38260057', 'https://openalex.org/I4210107168'], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 10.996, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 301, 'citation_normalized_percentile': {'value': 0.969199, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '68', 'issue': '4-5', 'first_page': '235', 'last_page': '244'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10176', 'display_name': 'Mesenchymal stem cell research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10176', 'display_name': 'Mesenchymal stem cell research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12264', 'display_name': 'Tissue Engineering and Regenerative Medicine', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9938, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transdifferentiation', 'display_name': 'Transdifferentiation', 'score': 0.7286344}, {'id': 'https://openalex.org/keywords/neurosphere', 'display_name': 'Neurosphere', 'score': 0.4518898}], 'concepts': [{'id': 'https://openalex.org/C2778761762', 'wikidata': 'https://www.wikidata.org/wiki/Q18252680', 'display_name': 'Noggin', 'level': 4, 'score': 0.8413777}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7486024}, {'id': 'https://openalex.org/C60870556', 'wikidata': 'https://www.wikidata.org/wiki/Q2300675', 'display_name': 'Transdifferentiation', 'level': 3, 'score': 0.7286344}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6600337}, {'id': 'https://openalex.org/C31507581', 'wikidata': 'https://www.wikidata.org/wiki/Q425383', 'display_name': 'Bone morphogenetic protein', 'level': 3, 'score': 0.5236761}, {'id': 'https://openalex.org/C2780007613', 'wikidata': 'https://www.wikidata.org/wiki/Q546523', 'display_name': 'Bone marrow', 'level': 2, 'score': 0.5163925}, {'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.48245865}, {'id': 'https://openalex.org/C162746124', 'wikidata': 'https://www.wikidata.org/wiki/Q7002675', 'display_name': 'Neurosphere', 'level': 5, 'score': 0.4518898}, {'id': 'https://openalex.org/C148738053', 'wikidata': 'https://www.wikidata.org/wiki/Q210861', 'display_name': 'Cellular differentiation', 'level': 3, 'score': 0.37559664}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.3698815}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33203265}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.27100614}, {'id': 'https://openalex.org/C20875687', 'wikidata': 'https://www.wikidata.org/wiki/Q2642600', 'display_name': 'Adult stem cell', 'level': 4, 'score': 0.2436688}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.08787423}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001374', 'descriptor_name': 'Azacitidine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D001854', 'descriptor_name': 'Bone Marrow Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D010006', 'descriptor_name': 'Osteoblasts', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001374', 'descriptor_name': 'Azacitidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001854', 'descriptor_name': 'Bone Marrow Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019070', 'descriptor_name': 'Cell Lineage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010006', 'descriptor_name': 'Osteoblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015221', 'descriptor_name': 'Potassium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015221', 'descriptor_name': 'Potassium Channels', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012038', 'descriptor_name': 'Regeneration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017154', 'descriptor_name': 'Stromal Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D017154', 'descriptor_name': 'Stromal Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1432-0436.2001.680411.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53475899', 'display_name': 'Differentiation', 'issn_l': '0301-4681', 'issn': ['0301-4681', '1432-0436'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11776476', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320909', 'funder_display_name': 'Keio University', 'award_id': None}, {'funder': 'https://openalex.org/F4320320912', 'funder_display_name': 'Ministry of Education, Culture, Sports, Science and Technology', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 48, 'referenced_works': ['https://openalex.org/W126539919', 'https://openalex.org/W1483365010', 'https://openalex.org/W1486183464', 'https://openalex.org/W1514351476', 'https://openalex.org/W1540384225', 'https://openalex.org/W1621991227', 'https://openalex.org/W1641958014', 'https://openalex.org/W179374708', 'https://openalex.org/W1810515927', 'https://openalex.org/W182299618', 'https://openalex.org/W1916250075', 'https://openalex.org/W1965174761', 'https://openalex.org/W1966476278', 'https://openalex.org/W1967556157', 'https://openalex.org/W1970895440', 'https://openalex.org/W1982022033', 'https://openalex.org/W1984288177', 'https://openalex.org/W1989920563', 'https://openalex.org/W1990854759', 'https://openalex.org/W1990938412', 'https://openalex.org/W1991248271', 'https://openalex.org/W2003275504', 'https://openalex.org/W2012333093', 'https://openalex.org/W2012976585', 'https://openalex.org/W2017013844', 'https://openalex.org/W2019767502', 'https://openalex.org/W2027839043', 'https://openalex.org/W2030251237', 'https://openalex.org/W2047165320', 'https://openalex.org/W2056056108', 'https://openalex.org/W2077213482', 'https://openalex.org/W2079884646', 'https://openalex.org/W2086793358', 'https://openalex.org/W2098015360', 'https://openalex.org/W2102812687', 'https://openalex.org/W2104384655', 'https://openalex.org/W2108143410', 'https://openalex.org/W2113327504', 'https://openalex.org/W2120695887', 'https://openalex.org/W2131282078', 'https://openalex.org/W2131388270', 'https://openalex.org/W2155138852', 'https://openalex.org/W2159999899', 'https://openalex.org/W2170560272', 'https://openalex.org/W2171560483', 'https://openalex.org/W2230781836', 'https://openalex.org/W2272066499', 'https://openalex.org/W62766884'], 'related_works': ['https://openalex.org/W2249041175', 'https://openalex.org/W2139983567', 'https://openalex.org/W2075010531', 'https://openalex.org/W2069439478', 'https://openalex.org/W2066906217', 'https://openalex.org/W2041924731', 'https://openalex.org/W1991469157', 'https://openalex.org/W1567815848', 'https://openalex.org/W1564111877', 'https://openalex.org/W1504484880'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2082312462', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 17}, {'year': 2012, 'cited_by_count': 20}], 'updated_date': '2024-12-16T18:12:35.867447', 'created_date': '2016-06-24'}