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1225], 'Cancer': [48, 62, 73, 76, 87, 90, 105, 119, 136, 152, 163, 166, 184, 427, 618, 723, 952, 1060, 1080, 1097, 1100, 1114, 1117, 1135, 1152, 1171, 1190, 1204, 1207, 1226], 'Center,': [49, 63, 77, 91, 106, 120, 137, 153, 167, 185, 1061, 1081, 1101, 1118, 1136, 1153, 1172, 1191, 1208, 1227], 'Gyeonggi-do,': [50, 64, 78, 92, 107, 121, 138, 154, 168, 186, 1062, 1082, 1102, 1119, 1137, 1154, 1173, 1192, 1209, 1228], 'Republic': [51, 65, 79, 93, 108, 122, 139, 155, 169, 187, 1063, 1083, 1103, 1120, 1138, 1155, 1174, 1193, 1210, 1229], 'Korea': [53, 67, 81, 95, 110, 124, 141, 157, 171, 189, 1065, 1085, 1105, 1122, 1140, 1157, 1176, 1195, 1212, 1231], ',': [54, 68, 82, 96, 111, 125, 142, 158, 172], 'KimKyung-Tae': [56], 'Kim': [57, 145, 1075, 1183], 'Molecular': [58, 115, 146, 1076, 1148, 1184], 'Epidemiology': [59, 116, 1077, 1149], 'SeoHye-Hyun': [70], 'Genitourinary': [72, 86, 162, 1096, 1113, 1203], 'ShinSeung-Pil': [84], 'Shin': [85, 1112], 'AhnKyung-Ohk': [98], 'Ahn': [99, 1129], 'JiMin-Ju': [113], 'Ji': [114, 1147], 'ParkWeon': [128], 'Park': [130, 1165], 'Center': [131, 179, 1166, 1221], 'for': [132, 180, 209, 417, 457, 475, 479, 514, 1167, 1222], 'Prostate': [133, 181, 1168, 1223], 'Cancer,': [134, 182, 1169, 1224], 'KimIn-Hoo': [144], 'Imaging': [147, 1185], 'Therapy': [149, 1187], 'LeeSang-Jin': [160], 'Lee': [161, 1202], 'SeoHo': [176], 'View': [190], 'All': [191, 1238], 'Author': [192, 1051], 'Informationhttps://doi.org/10.1016/j.juro.2013.07.019AboutFull': [193], 'TextPDF': [194], 'ToolsAdd': [195], 'to': [196, 252, 653, 758, 841, 947], 'favoritesDownload': [197], 'CitationsTrack': [198], 'CitationsPermissionsReprints': [199], 'ShareFacebookLinked': [200], 'InTwitterEmail': [201], 'Abstract': [202], 'Purpose:': [203], 'is': [205, 215], 'a': [206, 333, 390, 637, 755, 802, 936], 'promising': [207], 'target': [208, 253, 336, 358, 759], 'cancer': [210, 376, 424, 539, 772, 950], 'therapy': [211, 474], 'but': [212], 'its': [213, 288], 'use': [214], 'restricted': [216], 'by': [217, 267, 292, 310, 345, 378, 636, 773, 919, 935, 960, 1030, 1071, 1091, 1108, 1125, 1143, 1160, 1179, 1198, 1215, 1234], 'unwanted,': [218], 'devastating': [219], 'side': [220], 'effects.': [221], 'We': [222], 'explored': [223], 'whether': [224], 'intravesical': [225, 260, 318, 414], 'instillation': [226, 319, 386], 'the': [228, 500, 608, 616, 651, 669, 713, 870, 875], 'inhibitor': [230, 406, 805], 'could': [232, 408], 'suppress': [233, 690], 'tumor': [234, 397], 'growth': [235, 398], 'in': [236, 303, 322, 493, 536, 563, 584, 611, 631, 668, 717, 738, 771, 794, 847, 988, 1006], 'murine': [237, 323], 'orthotopic': [238, 324], 'bladder': [239, 325, 375, 418, 461, 495, 518, 538, 566, 673, 719, 740, 1039], 'xenografts.': [240, 326], 'Materials': [241], 'Methods:': [243], 'The': [244, 302, 354, 404], 'small': [245, 920], 'molecule': [246], 'KSI-3716,': [247], 'which': [248], 'blocks': [249], 'c-MYC/MAX': [250, 330], 'binding': [251, 861, 918], 'gene': [254, 337, 534, 715], 'promoters,': [255], 'was': [256, 265, 290, 308, 343, 367], 'used': [257], 'as': [258, 349, 351, 361, 411, 754], 'an': [259, 412], 'chemotherapy': [261, 415], 'agent.': [262], 'action': [264], 'assessed': [266], 'electrophoretic': [268], 'mobility': [269], 'shift': [270], 'assay,': [271, 295], 'chromatin': [272], 'immunoprecipitation,': [273], 'transcription': [274, 864], 'reporter': [275], 'assay': [276, 298], 'quantitative': [278], 'reverse': [279], 'transcriptase-polymerase': [280], 'chain': [281], 'reaction.': [282], 'Inhibition': [283], 'cell': [285, 293, 380, 698, 700], 'proliferation': [286, 691], 'mechanism': [289], 'monitored': [291], 'cytotoxicity': [294, 792], 'EdU': [296], 'incorporation': [297], 'flow': [300], 'cytometry.': [301], 'vivo': [304, 795], 'efficacy': [305], 'examined': [309], 'noninvasive': [311], 'luminescence': [312], 'imaging': [313], 'histological': [315], 'analysis': [316, 734], 'after': [317], 'Results:': [327], 'blocked': [329], 'from': [331], 'forming': [332], 'complex': [334], 'with': [335, 399, 558, 589, 982], 'promoters.': [338], 'mediated': [340], 'transcriptional': [341, 688], 'activity': [342], 'inhibited': [344], 'at': [347, 389], 'concentrations': [348], 'low': [350], '1': [352, 421], 'μM.': [353], 'expression': [355, 535, 603], 'genes,': [359], 'such': [360], 'cyclin': [362], 'D2,': [363], 'CDK4': [364], 'hTERT,': [366], 'markedly': [368], 'decreased.': [369], 'exerted': [371], 'cytotoxic': [372], 'effects': [373], 'on': [374, 650, 874], 'cells': [377], 'inducing': [379], 'cycle': [381, 701], 'arrest': [382], 'apoptosis.': [384], 'Intravesical': [385, 451, 473], 'dose': [391], '5': [393, 489], 'mg/kg': [394], 'significantly': [395], 'suppressed': [396], 'minimal': [400], 'systemic': [401], 'toxicity.': [402], 'Conclusions:': [403], 'be': [409], 'developed': [410], 'effective': [413], 'agent': [416], 'cancer.': [419, 462, 519, 654, 674, 720, 741], 'References': [420], ':': [422, 435, 450, 467, 472, 490, 510, 529, 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