Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2081277442', 'doi': 'https://doi.org/10.1089/ham.2005.6.50', 'title': 'Effect of a Repeated Series of Intermittent Hypoxic Exposures on Ventilatory Response in Humans', 'display_name': 'Effect of a Repeated Series of Intermittent Hypoxic Exposures on Ventilatory Response in Humans', 'publication_year': 2005, 'publication_date': '2005-03-01', 'ids': {'openalex': 'https://openalex.org/W2081277442', 'doi': 'https://doi.org/10.1089/ham.2005.6.50', 'mag': '2081277442', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15772500'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ham.2005.6.50', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75581497', 'display_name': 'High Altitude Medicine & Biology', 'issn_l': '1527-0297', 'issn': ['1527-0297', '1557-8682'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020210460', 'display_name': 'Keisho Katayama', 'orcid': 'https://orcid.org/0000-0001-7245-3496'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Keisho Katayama', 'raw_affiliation_strings': [' Research Center of Health, Physical Fitness, and Sports, Nagoya University, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': ' Research Center of Health, Physical Fitness, and Sports, Nagoya University, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027406783', 'display_name': 'Hiroshi Fujita', 'orcid': 'https://orcid.org/0000-0002-2936-9296'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Fujita', 'raw_affiliation_strings': ['School of Medicine, Nagoya University, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': 'School of Medicine, Nagoya University, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074854563', 'display_name': 'Kohei Sato', 'orcid': 'https://orcid.org/0000-0001-6877-9223'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kohei Sato', 'raw_affiliation_strings': ['Graduate School of Medicine, Nagoya University, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Graduate School of Medicine, Nagoya University, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074390442', 'display_name': 'Kōji Ishida', 'orcid': 'https://orcid.org/0000-0002-5630-7138'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Koji Ishida', 'raw_affiliation_strings': ['Research Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Research Center of Health, Physical Fitness and Sports, Nagoya University, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000034832', 'display_name': 'Ken‐ichi Iwasaki', 'orcid': 'https://orcid.org/0000-0003-2426-7773'}, 'institutions': [{'id': 'https://openalex.org/I104946051', 'display_name': 'Nihon University', 'ror': 'https://ror.org/05jk51a88', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I104946051']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ken-Ichi Iwasaki', 'raw_affiliation_strings': ['Department of Hygiene and Space Medicine, Nihon University School of Medicine, Tokyo, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Hygiene and Space Medicine, Nihon University School of Medicine, Tokyo, Japan.', 'institution_ids': ['https://openalex.org/I104946051']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112069317', 'display_name': 'Miharu Miyamura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I175135595', 'display_name': 'Tokai Gakuen University', 'ror': 'https://ror.org/03aet8853', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I175135595']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Miharu Miyamura', 'raw_affiliation_strings': ['Faculty of Wellness, Tokai Gakuen University, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Faculty of Wellness, Tokai Gakuen University, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I175135595']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.692, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.832561, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '6', 'issue': '1', 'first_page': '50', 'last_page': '59'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11968', 'display_name': 'High Altitude and Hypoxia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11968', 'display_name': 'High Altitude and Hypoxia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11456', 'display_name': 'Neuroscience of respiration and sleep', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11579', 'display_name': 'Cardiovascular and Diving-Related Complications', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hypoxia', 'display_name': 'Hypoxia', 'score': 0.720482}, {'id': 'https://openalex.org/keywords/hypoxic-ventilatory-response', 'display_name': 'Hypoxic ventilatory response', 'score': 0.55767995}], 'concepts': [{'id': 'https://openalex.org/C2777449187', 'wikidata': 'https://www.wikidata.org/wiki/Q575168', 'display_name': 'Hyperventilation', 'level': 2, 'score': 0.84152126}, {'id': 'https://openalex.org/C7836513', 'wikidata': 'https://www.wikidata.org/wiki/Q1641506', 'display_name': 'Hypoxia (environmental)', 'level': 3, 'score': 0.720482}, {'id': 'https://openalex.org/C182215343', 'wikidata': 'https://www.wikidata.org/wiki/Q472287', 'display_name': 'Respiration', 'level': 2, 'score': 0.56062526}, {'id': 'https://openalex.org/C2780157289', 'wikidata': 'https://www.wikidata.org/wiki/Q16918363', 'display_name': 'Hypoxic ventilatory response', 'level': 3, 'score': 0.55767995}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.55284363}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4877823}, {'id': 'https://openalex.org/C530467964', 'wikidata': 'https://www.wikidata.org/wiki/Q1997', 'display_name': 'Carbon dioxide', 'level': 2, 'score': 0.46617436}, {'id': 'https://openalex.org/C200457457', 'wikidata': 'https://www.wikidata.org/wiki/Q584049', 'display_name': 'Ventilation (architecture)', 'level': 2, 'score': 0.44357994}, {'id': 'https://openalex.org/C2779594553', 'wikidata': 'https://www.wikidata.org/wiki/Q1641494', 'display_name': 'Hypoventilation', 'level': 3, 'score': 0.43086377}, {'id': 'https://openalex.org/C540031477', 'wikidata': 'https://www.wikidata.org/wiki/Q629', 'display_name': 'Oxygen', 'level': 2, 'score': 0.35178828}, {'id': 'https://openalex.org/C534529494', 'wikidata': 'https://www.wikidata.org/wiki/Q7891', 'display_name': 'Respiratory system', 'level': 2, 'score': 0.2864532}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.25993043}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.21328962}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.09346008}, {'id': 'https://openalex.org/C153294291', 'wikidata': 'https://www.wikidata.org/wiki/Q25261', 'display_name': 'Meteorology', 'level': 1, 'score': 0.06793231}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000064', 'descriptor_name': 'Acclimatization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000222', 'descriptor_name': 'Adaptation, Physiological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015656', 'descriptor_name': 'Respiratory Mechanics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000704', 'descriptor_name': 'Analysis of Variance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000860', 'descriptor_name': 'Hypoxia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D000860', 'descriptor_name': 'Hypoxia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012123', 'descriptor_name': 'Pulmonary Ventilation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012016', 'descriptor_name': 'Reference Values', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012129', 'descriptor_name': 'Respiratory Function Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ham.2005.6.50', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75581497', 'display_name': 'High Altitude Medicine & Biology', 'issn_l': '1527-0297', 'issn': ['1527-0297', '1557-8682'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15772500', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/6', 'score': 0.72, 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1029480417', 'https://openalex.org/W1875259407', 'https://openalex.org/W1917642441', 'https://openalex.org/W1964530016', 'https://openalex.org/W1969868463', 'https://openalex.org/W1976858412', 'https://openalex.org/W1985013374', 'https://openalex.org/W2027779644', 'https://openalex.org/W2034357716', 'https://openalex.org/W2079340250', 'https://openalex.org/W2085518088', 'https://openalex.org/W2114284145', 'https://openalex.org/W2115840924', 'https://openalex.org/W2151986660', 'https://openalex.org/W2177265491', 'https://openalex.org/W2178747552', 'https://openalex.org/W2190090695', 'https://openalex.org/W2252689755', 'https://openalex.org/W2287740762', 'https://openalex.org/W4285719527', 'https://openalex.org/W591380511'], 'related_works': ['https://openalex.org/W4312210404', 'https://openalex.org/W3194543307', 'https://openalex.org/W2089818623', 'https://openalex.org/W2069087936', 'https://openalex.org/W2056024926', 'https://openalex.org/W2044875387', 'https://openalex.org/W2035352644', 'https://openalex.org/W2008430621', 'https://openalex.org/W1990398013', 'https://openalex.org/W1531036663'], 'abstract_inverted_index': {'Katayama,': [0], 'Keisho,': [1], 'Hiroshi': [2], 'Fujita,': [3], 'Kohei': [4], 'Sato,': [5], 'Koji': [6], 'Ishida,': [7], 'Ken-Ichi': [8], 'Iwasaki,': [9], 'and': [10, 42, 88, 110, 130, 162], 'Miharu': [11], 'Miyamura.': [12], 'Effect': [13], 'of': [14, 18, 34, 46, 54, 83, 142, 151, 198, 205, 208], 'a': [15, 51, 97, 206], 'repeated': [16, 52], 'series': [17, 53, 146, 152, 173, 207], 'intermittent': [19, 143], 'hypoxic': [20, 55, 98, 121, 136, 184, 189], 'exposures': [21], 'on': [22, 169], 'ventilatory': [23, 47], 'response': [24], 'in': [25, 61, 70, 96, 134, 145, 195, 200], 'humans.': [26], 'High': [27], 'Alt.': [28], 'Med.': [29], 'Biol.': [30], '6:50–59,': [31], '2005—.The': [32], 'purpose': [33], 'this': [35], 'study': [36], 'was': [37, 159, 164], 'to': [38, 156, 188, 192, 210], 'elucidate': [39], 'the': [40, 43, 62, 115, 135, 139, 149, 196, 201], 'magnitude': [41, 197], 'time': [44], 'course': [45], 'changes': [48], 'resulting': [49], 'from': [50, 120], 'exposures.': [56], 'Eight': [57], 'healthy': [58], 'males': [59], 'participated': [60], 'present': [63], 'study.': [64], 'The': [65], 'subjects': [66, 116], 'spent': [67], '1': [68, 124, 155, 171], 'h/day': [69], 'normobaric': [71], 'hypoxia': [72, 144], '(12%': [73], 'inspired': [74], 'oxygen).': [75], 'Inspired': [76], 'minute': [77], 'ventilation': [78], ',': [79], 'end-tidal': [80], 'partial': [81], 'pressure': [82], 'carbon': [84], 'dioxide': [85], '(PETCO2': [86], '),': [87], 'arterial': [89], 'oxygen': [90], 'saturation': [91], '(SaO2': [92], ')': [93], 'were': [94, 102, 111], 'measured': [95], 'tent.': [99], 'These': [100, 175], 'measurements': [101], 'taken': [103, 112], 'for': [104, 123], '10': [105, 140], 'consecutive': [106], 'days': [107, 141, 204], '(series': [108, 126], '1),': [109], 'again': [113], 'after': [114], 'had': [117, 182], 'been': [118], 'away': [119], 'exposure': [122, 185], 'month': [125], '2).': [127], 'PETCO2': [128, 158], 'decreased': [129], 'SaO2': [131, 163], 'increased': [132], 'progressively': [133], 'tent': [137], 'during': [138, 172], '1.': [147, 174], 'At': [148], 'onset': [150], '2': [153], '(days': [154], '3),': [157], 'significantly': [160, 165], 'lower': [161], 'higher': [166], 'than': [167], 'those': [168], 'day': [170], 'results': [176], 'suggest': [177], 'that': [178], 'humans': [179], 'who': [180], 'have': [181], 'previous': [183], 'adapt': [186], 'sooner': [187], 'condition': [190], 'due': [191], 'an': [193], 'increase': [194], 'hyperventilation': [199], 'first': [202], 'few': [203], 'reexposures': [209], 'hypoxia.': [211]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2081277442', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-06T04:05:14.625233', 'created_date': '2016-06-24'}