Publication Information

{'id': 'https://openalex.org/W2080927482', 'doi': 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.x', 'title': 'Drug therapy of ulcerative colitis.', 'display_name': 'Drug therapy of ulcerative colitis.', 'publication_year': 1992, 'publication_date': '1992-09-01', 'ids': {'openalex': 'https://openalex.org/W2080927482', 'doi': 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.x', 'mag': '2080927482', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1389944', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1381388'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2125.1992.tb04124.x', 'source': {'id': 'https://openalex.org/S13842274', 'display_name': 'British Journal of Clinical Pharmacology', 'issn_l': '0306-5251', 'issn': ['0306-5251', '1365-2125'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2125.1992.tb04124.x', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5065214790', 'display_name': 'Brendan Crotty', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'B Crotty', 'raw_affiliation_strings': ['Gastroenterology Unit, Radcliffe Infirmary, Oxford.'], 'affiliations': [{'raw_affiliation_string': 'Gastroenterology Unit, Radcliffe Infirmary, Oxford.', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113625600', 'display_name': 'D P Jewell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'DP Jewell', 'raw_affiliation_strings': ['Gastroenterology Unit, Radcliffe Infirmary, Oxford.'], 'affiliations': [{'raw_affiliation_string': 'Gastroenterology Unit, Radcliffe Infirmary, Oxford.', 'institution_ids': ['https://openalex.org/I40120149']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4330, 'currency': 'USD', 'value_usd': 4330, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.949, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.790757, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '34', 'issue': '3', 'first_page': '189', 'last_page': '198'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10134', 'display_name': 'Inflammatory Bowel Disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10134', 'display_name': 'Inflammatory Bowel Disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10276', 'display_name': 'Helicobacter pylori-related gastroenterology studies', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13569', 'display_name': 'Microscopic Colitis', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pharmacotherapy', 'display_name': 'Pharmacotherapy', 'score': 0.4652646}], 'concepts': [{'id': 'https://openalex.org/C2780479503', 'wikidata': 'https://www.wikidata.org/wiki/Q1477', 'display_name': 'Ulcerative colitis', 'level': 3, 'score': 0.8751895}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6836406}, {'id': 'https://openalex.org/C2775862500', 'wikidata': 'https://www.wikidata.org/wiki/Q2453464', 'display_name': 'Colitis', 'level': 2, 'score': 0.49621874}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.4901422}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4856664}, {'id': 'https://openalex.org/C500440147', 'wikidata': 'https://www.wikidata.org/wiki/Q701216', 'display_name': 'Pharmacotherapy', 'level': 2, 'score': 0.4652646}, {'id': 'https://openalex.org/C16005928', 'wikidata': 'https://www.wikidata.org/wiki/Q171171', 'display_name': 'Dermatology', 'level': 1, 'score': 0.37372005}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.14177632}], 'mesh': [{'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D003093', 'descriptor_name': 'Colitis, Ulcerative', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D012459', 'descriptor_name': 'Salicylates', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003093', 'descriptor_name': 'Colitis, Ulcerative', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011248', 'descriptor_name': 'Pregnancy Complications', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011248', 'descriptor_name': 'Pregnancy Complications', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D012459', 'descriptor_name': 'Salicylates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012459', 'descriptor_name': 'Salicylates', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2125.1992.tb04124.x', 'source': {'id': 'https://openalex.org/S13842274', 'display_name': 'British Journal of Clinical Pharmacology', 'issn_l': '0306-5251', 'issn': ['0306-5251', '1365-2125'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1381388', 'pdf_url': 'https://europepmc.org/articles/pmc1381388?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1381388', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1389944', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2125.1992.tb04124.x', 'source': {'id': 'https://openalex.org/S13842274', 'display_name': 'British Journal of Clinical Pharmacology', 'issn_l': '0306-5251', 'issn': ['0306-5251', '1365-2125'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.6}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 159, 'referenced_works': ['https://openalex.org/W103277852', 'https://openalex.org/W10339549', 'https://openalex.org/W12972203', 'https://openalex.org/W138805643', 'https://openalex.org/W1408503105', 'https://openalex.org/W143684004', 'https://openalex.org/W148987601', 'https://openalex.org/W1497617769', 'https://openalex.org/W1549056153', 'https://openalex.org/W1553613620', 'https://openalex.org/W1566382259', 'https://openalex.org/W1584782374', 'https://openalex.org/W1591788802', 'https://openalex.org/W1597746336', 'https://openalex.org/W166805679', 'https://openalex.org/W1706367474', 'https://openalex.org/W1737578516', 'https://openalex.org/W1820364384', 'https://openalex.org/W1835567156', 'https://openalex.org/W1904618836', 'https://openalex.org/W1921816141', 'https://openalex.org/W1962224684', 'https://openalex.org/W1964233609', 'https://openalex.org/W1964607500', 'https://openalex.org/W1965058283', 'https://openalex.org/W1966725132', 'https://openalex.org/W1967920619', 'https://openalex.org/W1969729957', 'https://openalex.org/W1969812496', 'https://openalex.org/W1970901287', 'https://openalex.org/W1972578648', 'https://openalex.org/W1973392565', 'https://openalex.org/W1974104914', 'https://openalex.org/W1974348321', 'https://openalex.org/W1979456617', 'https://openalex.org/W1979915837', 'https://openalex.org/W1981542183', 'https://openalex.org/W1981655586', 'https://openalex.org/W1987791487', 'https://openalex.org/W1988774893', 'https://openalex.org/W1989304148', 'https://openalex.org/W1989740133', 'https://openalex.org/W1991776975', 'https://openalex.org/W1995287714', 'https://openalex.org/W1996166904', 'https://openalex.org/W1997310223', 'https://openalex.org/W1999197985', 'https://openalex.org/W2002409140', 'https://openalex.org/W2003106549', 'https://openalex.org/W2003681655', 'https://openalex.org/W2005049926', 'https://openalex.org/W2006352270', 'https://openalex.org/W2008160869', 'https://openalex.org/W2009944327', 'https://openalex.org/W2010946554', 'https://openalex.org/W2011737172', 'https://openalex.org/W2013064714', 'https://openalex.org/W2015471143', 'https://openalex.org/W2019657479', 'https://openalex.org/W2019834913', 'https://openalex.org/W2023708763', 'https://openalex.org/W202399948', 'https://openalex.org/W2024513902', 'https://openalex.org/W2024842574', 'https://openalex.org/W2030514882', 'https://openalex.org/W2031302253', 'https://openalex.org/W2034545522', 'https://openalex.org/W203984136', 'https://openalex.org/W2040590993', 'https://openalex.org/W2041775926', 'https://openalex.org/W2043530745', 'https://openalex.org/W2045529122', 'https://openalex.org/W2045538930', 'https://openalex.org/W2046473863', 'https://openalex.org/W2046670080', 'https://openalex.org/W2047690012', 'https://openalex.org/W2048683851', 'https://openalex.org/W2050712578', 'https://openalex.org/W2051978401', 'https://openalex.org/W2056817635', 'https://openalex.org/W2061928454', 'https://openalex.org/W2065780155', 'https://openalex.org/W2068500369', 'https://openalex.org/W2069108699', 'https://openalex.org/W2069718379', 'https://openalex.org/W2069874724', 'https://openalex.org/W2070764875', 'https://openalex.org/W2073249726', 'https://openalex.org/W2075506798', 'https://openalex.org/W2075833014', 'https://openalex.org/W2079919388', 'https://openalex.org/W2081067304', 'https://openalex.org/W2081164704', 'https://openalex.org/W2084283951', 'https://openalex.org/W2085876808', 'https://openalex.org/W2087489602', 'https://openalex.org/W2088738262', 'https://openalex.org/W2089455641', 'https://openalex.org/W2089806722', 'https://openalex.org/W2090568923', 'https://openalex.org/W2093904837', 'https://openalex.org/W2094163077', 'https://openalex.org/W2094450043', 'https://openalex.org/W2095405277', 'https://openalex.org/W2096326818', 'https://openalex.org/W2097994780', 'https://openalex.org/W2098211926', 'https://openalex.org/W2098303853', 'https://openalex.org/W2099078767', 'https://openalex.org/W2099445096', 'https://openalex.org/W2099450737', 'https://openalex.org/W2100970832', 'https://openalex.org/W2102818528', 'https://openalex.org/W2106414295', 'https://openalex.org/W2107729707', 'https://openalex.org/W2113622525', 'https://openalex.org/W2114344731', 'https://openalex.org/W2122139341', 'https://openalex.org/W2124744509', 'https://openalex.org/W2126499833', 'https://openalex.org/W2129196336', 'https://openalex.org/W2129463597', 'https://openalex.org/W2135287750', 'https://openalex.org/W2136236138', 'https://openalex.org/W2140915269', 'https://openalex.org/W2158106931', 'https://openalex.org/W2158858344', 'https://openalex.org/W2160641770', 'https://openalex.org/W2163091610', 'https://openalex.org/W2164322090', 'https://openalex.org/W2165223364', 'https://openalex.org/W2166930089', 'https://openalex.org/W2171789845', 'https://openalex.org/W2179681930', 'https://openalex.org/W2253251593', 'https://openalex.org/W2321334948', 'https://openalex.org/W2339392592', 'https://openalex.org/W2396370145', 'https://openalex.org/W2402574446', 'https://openalex.org/W2402925372', 'https://openalex.org/W2404854108', 'https://openalex.org/W2411840308', 'https://openalex.org/W2414475801', 'https://openalex.org/W2415775034', 'https://openalex.org/W2429405358', 'https://openalex.org/W2435135945', 'https://openalex.org/W2460075134', 'https://openalex.org/W2614323529', 'https://openalex.org/W267429781', 'https://openalex.org/W272430401', 'https://openalex.org/W2910062148', 'https://openalex.org/W315764148', 'https://openalex.org/W35165947', 'https://openalex.org/W4246095671', 'https://openalex.org/W4247465937', 'https://openalex.org/W4300100492', 'https://openalex.org/W4300931992', 'https://openalex.org/W53013579', 'https://openalex.org/W85580240'], 'related_works': ['https://openalex.org/W4385147599', 'https://openalex.org/W4224234790', 'https://openalex.org/W3151390891', 'https://openalex.org/W2944370844', 'https://openalex.org/W2393318770', 'https://openalex.org/W2391150797', 'https://openalex.org/W2381376498', 'https://openalex.org/W2378399001', 'https://openalex.org/W2369056725', 'https://openalex.org/W2060356349'], 'abstract_inverted_index': {'British': [0], 'Journal': [1], 'of': [2, 14, 100, 110, 123, 134, 170, 260, 292, 322, 337, 377, 403, 410, 454, 494, 564, 584, 607, 650, 680, 688, 770, 803, 851, 909, 934, 963, 972, 1014, 1041, 1044, 1072, 1121, 1124, 1139, 1196, 1216, 1280, 1347, 1382, 1387, 1420, 1459, 1473, 1501, 1510, 1547, 1564, 1582, 1608, 1615, 1642, 1667, 1711, 1729, 1758, 1811, 1834, 1866, 1887, 1913, 1916, 1955, 1988, 2045, 2060, 2062, 2093, 2110, 2155, 2184, 2207, 2233, 2240, 2261, 2302, 2452, 2471, 2553, 2568, 2592, 2636, 2690, 2712, 2740, 2801, 2807, 2837, 2844, 2868, 2885, 2887, 2915, 2951, 2956, 2961, 2966, 2993, 3018, 3040, 3048, 3074, 3079, 3137, 3218, 3269, 3292, 3347, 3371, 3377, 3394, 3414, 3421, 3469, 3489, 3515, 3539, 3565, 3589, 3617, 3664, 3730, 3735, 3764, 3776, 3805, 3841, 3869, 3874, 3898, 3916, 3933, 3939, 3958, 3979, 3994, 4052, 4075, 4103, 4130, 4175, 4180, 4201, 4226, 4254, 4316, 4335, 4382, 4491, 4527, 4546, 4570, 4650, 4658, 4700, 4749, 4787, 4816], 'Clinical': [3, 208], 'PharmacologyVolume': [4], '34,': [5], 'Issue': [6], '3': [7], 'p.': [8], '189-198': [9, 4836], 'Free': [10], 'Access': [11], 'Drug': [12, 2245], 'therapy': [13, 710, 772, 1253, 1313, 1472, 3022, 4363, 4386], 'ulcerative': [15, 240, 271, 298, 404, 437, 529, 565, 590, 608, 632, 805, 827, 857, 919, 935, 973, 993, 1022, 1082, 1103, 1241, 1356, 1421, 1511, 1568, 1583, 1609, 1649, 1760, 1788, 1813, 1873, 1951, 1994, 2094, 2133, 2156, 2211, 2269, 2435, 2475, 2500, 2534, 2565, 2648, 2669, 2715, 2809, 2871, 2958, 2994, 3024, 3146, 3519, 3543, 3591, 3665, 3780, 3820, 3843, 3876, 3892, 3917, 4032, 4054, 4183, 4336, 4365, 4388, 4405, 4428, 4453, 4705, 4757, 4789, 4822], 'colitis.': [16, 241, 272, 299, 405, 438, 530, 591, 633, 828, 858, 920, 974, 1023, 1083, 1104, 1225, 1357, 1399, 1475, 1512, 1549, 1569, 1650, 1713, 1789, 1874, 2095, 2212, 2436, 2476, 2535, 2649, 2716, 2773, 2810, 2872, 2995, 3025, 3147, 3477, 3520, 3544, 3821, 3844, 3877, 3918, 4033, 4184, 4255, 4366, 4389, 4406, 4429, 4454, 4706, 4758, 4790, 4823], 'B': [17, 19, 46, 48, 3494], 'Crotty,': [18, 47, 1145, 1173], 'Crotty': [20, 49], 'Gastroenterology': [21, 35, 50, 64], 'Unit,': [22, 36, 51, 65], 'Radcliffe': [23, 37, 52, 66], 'Infirmary,': [24, 38, 53, 67], 'Oxford.Search': [25, 39, 54, 68], 'for': [26, 40, 55, 69, 237, 270, 294, 711, 823, 1871, 2089, 2152, 2236, 2363, 2503, 2647, 2668, 2913, 3023, 3817, 4495, 4643, 4756, 4784], 'more': [27, 41, 56, 70], 'papers': [28, 42, 57, 71], 'by': [29, 43, 58, 72, 461, 647, 661, 677, 2113, 2425, 2466, 2556, 2743, 2891, 3353, 3496, 3740, 4106], 'this': [30, 44, 59, 73, 135], 'authorDP': [31, 60], 'Jewell,': [32, 61, 230, 1066, 1094, 1153, 1183, 2037, 2055, 2078, 2105, 2123, 2147, 3068, 3725, 3832, 4025, 4046, 4774], 'DP': [33, 62], 'Jewell': [34, 63], 'author': [45, 74], 'First': [75], 'published:': [76], 'September': [77], '1992': [78], 'https://doi.org/10.1111/j.1365-2125.1992.tb04124.xCitations:': [79], '50AboutPDF': [80], 'ToolsRequest': [81], 'permissionExport': [82], 'citationAdd': [83], 'to': [84, 106, 129, 316, 371, 959, 966, 997, 1078, 1198, 1430, 1469, 3109, 3213, 3238, 3778, 4204, 4540], 'favoritesTrack': [85], 'citation': [86], 'ShareShare': [87], 'Give': [88], 'accessShare': [89, 92], 'full': [90], 'text': [91], 'full-text': [93, 108, 132], 'accessPlease': [94], 'review': [95, 1912], 'our': [96], 'Terms': [97, 120], 'and': [98, 102, 114, 121, 140, 209, 262, 341, 346, 375, 433, 472, 567, 659, 1046, 1118, 1163, 1282, 1290, 1314, 1320, 1385, 1389, 1396, 1462, 1521, 1587, 1590, 1620, 1680, 1918, 2065, 2087, 2158, 2263, 2271, 2300, 2330, 2403, 2432, 2456, 2461, 2495, 2558, 2574, 2597, 2604, 2608, 2639, 3042, 3140, 3156, 3185, 3298, 3396, 3439, 3508, 3518, 3569, 3619, 3623, 3626, 3704, 3733, 3771, 3812, 3931, 3956, 3961, 3977, 3998, 4004, 4224, 4273, 4360, 4384, 4450, 4493, 4531, 4573, 4614, 4679, 4683, 4722, 4744, 4818], 'Conditions': [99, 122], 'Use': [101], 'check': [103], 'box': [104], 'below': [105, 128], 'share': [107, 130], 'version': [109, 133], 'article.I': [111], 'have': [112], 'read': [113], 'accept': [115], 'the': [116, 126, 318, 368, 562, 651, 681, 961, 1042, 1315, 1383, 1470, 1709, 2090, 2153, 2237, 2298, 2507, 2805, 2954, 2962, 2967, 2990, 3046, 3077, 3080, 3215, 3253, 3375, 3513, 3587, 3774, 3839, 3872, 3914, 3959, 4101, 4199, 4222, 4314, 4542, 4655, 4785], 'Wiley': [117], 'Online': [118], 'Library': [119], 'UseShareable': [124], 'LinkUse': [125], 'link': [127], 'a': [131, 146, 213, 1956, 1996, 2138, 2393, 2694, 2766, 2834, 3293, 3417, 3473, 3562, 3593, 3697, 3934, 4177, 4346, 4410, 4433, 4538, 4648, 4752], 'article': [136], 'with': [137, 267, 498, 610, 627, 631, 807, 917, 937, 1020, 1317, 1398, 1423, 1585, 1611, 1762, 1815, 1837, 2024, 2189, 2268, 2335, 2395, 2434, 2564, 2595, 2849, 2897, 3103, 3322, 3567, 3819, 3944, 4056, 4321, 4338, 4535, 4580], 'your': [138], 'friends': [139], 'colleagues.': [141], 'Learn': [142], 'more.Copy': [143], 'URL': [144], 'Share': [145], 'linkShare': [147], 'onEmailFacebookTwitterLinkedInRedditWechat': [148], 'References': [149], 'Allgayer,': [150], 'H.,': [151, 386, 420, 481, 700, 2582, 2935, 2937, 3309, 3529, 3603, 3606, 3684, 3904, 3923, 4159, 4734], 'Ahnfelt,': [152], 'N.O.,': [153], 'Kruis,': [154], 'W.,': [155, 839, 1061, 1853, 3126], 'Klotz,': [156, 2218], 'U.,': [157, 758, 2219, 2250, 4281, 4477], 'Frank-Holmberg,': [158], 'K.,': [159, 279, 306, 728, 1574, 1695, 1930, 2252, 2412, 2441, 2481, 2523, 2545, 2681, 4119, 4146, 4469, 4732], 'Soderberg,': [160], 'H.': [161, 253, 603, 623, 1150, 1483, 2004, 2076, 2227, 2705, 2863, 2983, 3010, 3133, 3229, 3263, 3403, 3536, 3555, 3691, 3859, 3969, 4023, 4237, 4285, 4518, 4523], 'N.': [162, 507, 796, 814, 873, 1370, 1751, 3091, 3120, 4215, 4610, 4736], 'A.': [163, 278, 305, 355, 388, 422, 600, 620, 818, 841, 928, 949, 982, 1007, 1304, 1410, 1443, 1493, 1518, 1720, 1744, 1827, 1898, 1926, 1964, 2035, 2053, 2171, 2198, 2621, 2624, 2661, 2824, 3006, 3056, 3209, 3334, 3364, 3387, 3552, 3556, 3602, 3614, 3642, 3723, 3761, 3802, 3830, 3854, 4291, 4307, 4486, 4514, 4558], '&': [164, 197, 229, 254, 285, 309, 330, 357, 396, 427, 448, 488, 514, 555, 577, 601, 621, 640, 670, 704, 761, 797, 816, 843, 874, 903, 929, 950, 983, 1008, 1033, 1065, 1093, 1113, 1152, 1182, 1208, 1272, 1305, 1341, 1377, 1415, 1452, 1491, 1534, 1559, 1577, 1602, 1635, 1661, 1700, 1722, 1752, 1777, 1804, 1824, 1858, 1881, 1900, 1943, 1982, 2036, 2054, 2077, 2104, 2126, 2176, 2200, 2255, 2292, 2322, 2356, 2387, 2417, 2447, 2487, 2526, 2548, 2586, 2630, 2659, 2684, 2702, 2734, 2758, 2795, 2826, 2860, 2880, 2908, 2946, 2981, 3011, 3035, 3067, 3095, 3131, 3178, 3207, 3230, 3264, 3287, 3314, 3338, 3365, 3388, 3405, 3459, 3533, 3553, 3610, 3653, 3689, 3724, 3758, 3799, 3831, 3861, 3907, 3926, 3970, 4024, 4045, 4068, 4095, 4124, 4168, 4193, 4238, 4265, 4289, 4377, 4398, 4421, 4444, 4484, 4519, 4560, 4607, 4638, 4670, 4693, 4715, 4738, 4773, 4808], 'Paumgartner,': [165], 'G.': [166, 196, 643, 673, 927, 931, 948, 981, 1006, 1207, 1454, 1579, 1601, 2172, 2730, 2858, 3090, 3119, 3458, 3609, 3906, 3928, 4017, 4288, 4376, 4379, 4768], '(1989).': [167, 604, 1251, 1519, 1861, 1904, 2150, 2326, 2738, 3290, 3506, 3657, 4592, 4611], 'Colonic': [168, 1345, 2421, 2491], 'N-acetylation': [169], '5': [171, 3767, 3808], 'amino': [172], 'salicylic': [173, 3694], 'acid': [174, 269, 520, 586, 911, 965, 968, 988, 1016, 1237, 1349, 1392, 1426, 1705, 1764, 1783, 2064, 2112, 2235, 2455, 2555, 2832, 3246, 3271, 3295, 3491, 3695, 3769, 3810, 4318, 4530, 4572, 4576, 4703, 4779], 'in': [175, 205, 212, 264, 297, 367, 436, 524, 527, 561, 589, 629, 773, 825, 854, 915, 969, 992, 1018, 1048, 1080, 1101, 1129, 1159, 1189, 1222, 1240, 1254, 1286, 1354, 1393, 1427, 1507, 1544, 1567, 1648, 1676, 1708, 1733, 1785, 1890, 1907, 1920, 1950, 1990, 1993, 2009, 2022, 2042, 2132, 2186, 2209, 2266, 2333, 2426, 2429, 2468, 2473, 2498, 2506, 2533, 2562, 2601, 2671, 2692, 2710, 2771, 2804, 2841, 2870, 2922, 2953, 2989, 3020, 3076, 3100, 3142, 3145, 3161, 3187, 3220, 3236, 3248, 3275, 3374, 3423, 3476, 3512, 3541, 3559, 3586, 3629, 3661, 3696, 3706, 3773, 3838, 3871, 3890, 3894, 3913, 3942, 3981, 4030, 4135, 4182, 4249, 4299, 4313, 4319, 4364, 4387, 4404, 4427, 4452, 4504, 4533, 4578, 4621, 4654, 4677, 4704, 4746, 4781, 4820], 'inflammatory': [176, 338, 372, 1160, 1190, 1255, 1737, 1908, 2010, 2241, 2337, 2365, 2850, 2898, 4136, 4322], 'bowel': [177, 339, 373, 1099, 1161, 1191, 1256, 1278, 1464, 1738, 1909, 2011, 2242, 2338, 2366, 2802, 2851, 2899, 3435, 4137, 4323], 'disease.': [178, 569, 713, 777, 1257, 1739, 1910, 2012, 2027, 2160, 2243, 2273, 2339, 2852, 2900, 4138, 4302, 4324, 4498], 'Gastroenterology,': [179, 500, 531, 634, 717, 1292, 1476, 1550, 1570, 1740, 1818, 1840, 1875, 1960, 2000, 2304, 2437, 2477, 2746, 2970, 2996, 3111, 3148, 3399, 3545, 3708, 3822, 3878, 3899, 3919, 4139, 4185, 4508, 4624, 4664, 4685], '97,': [180], '38–41.': [181], 'Anderson,': [182], 'P.': [183, 232, 249, 328, 516, 554, 638, 668, 763, 1068, 1096, 1155, 1185, 1303, 1605, 1699, 1826, 1974, 2039, 2057, 2080, 2107, 2125, 2149, 2199, 2750, 2778, 2794, 3070, 3313, 3367, 3390, 3535, 3608, 3648, 3727, 3834, 3882, 4027, 4048, 4170, 4513, 4557, 4564, 4714, 4776], 'A.,': [184, 226, 247, 250, 736, 753, 894, 1110, 1205, 1300, 1969, 2073, 2100, 2282, 2288, 2309, 2318, 2822, 3032, 3173, 3200, 3649, 3747, 3788, 4020, 4064, 4479, 4554, 4769], 'West,': [185], 'S.': [186, 287, 311, 490, 513, 576, 702, 707, 725, 795, 819, 835, 1064, 1664, 1780, 1799, 1822, 1844, 1883, 1945, 2019, 2128, 2701, 2724, 2783, 2857, 2945, 2948, 3034, 3066, 3266, 3484, 3637, 3638, 3641, 3675, 3683, 3688, 3746, 3757, 3787, 3798, 3952, 4006, 4263, 4331, 4356, 4373, 4396, 4419, 4442, 4668, 4695, 4717, 4740, 4771, 4803], 'G.,': [187, 392, 1373, 1441, 1631, 1693, 4475, 4631], "O'Dell,": [188], 'J.': [189, 225, 284, 308, 329, 349, 360, 385, 394, 419, 425, 464, 487, 491, 593, 613, 703, 780, 845, 876, 1054, 1092, 1112, 1180, 1227, 1268, 1274, 1302, 1325, 1343, 1359, 1379, 1401, 1417, 1593, 1630, 1682, 1794, 1802, 1857, 1880, 1903, 1984, 2005, 2030, 2048, 2102, 2175, 2202, 2276, 2291, 2386, 2419, 2449, 2489, 2511, 2528, 2547, 2588, 2613, 2618, 2654, 2657, 2658, 2677, 2680, 2757, 2760, 2786, 2793, 2901, 2924, 2979, 3000, 3003, 3009, 3062, 3087, 3116, 3206, 3223, 3278, 3316, 3337, 3340, 3358, 3379, 3404, 3425, 3443, 3451, 3461, 3499, 3551, 3712, 3715, 3719, 3845, 3851, 3860, 3863, 3947, 4063, 4066, 4086, 4108, 4192, 4195, 4229, 4240, 4401, 4424, 4447, 4517, 4522, 4563, 4628, 4634, 4673, 4692, 4708, 4731, 4792, 4807, 4810, 4825], 'R.,': [190, 738, 836, 870, 1030, 1269, 1445, 1531, 1554, 2173, 2347, 2725, 2784, 2816, 2939, 4635, 4804], 'Via,': [191], 'C.': [192, 246, 256, 288, 312, 866, 869, 985, 1010, 1088, 1450, 1517, 1879, 1884, 1902, 1932, 1967, 1971, 2075, 2129, 2254, 2346, 2627, 2686, 2687, 2818, 2828, 3086, 3115, 3454, 3457, 3645, 3655, 4022, 4292, 4332, 4357, 4397, 4420, 4443, 4689, 4696, 4713, 4718, 4728, 4741, 4763, 4772, 4797], 'S.,': [193, 484, 598, 618, 1371, 1748, 2444, 2484, 2519, 2541, 2731, 2974, 3175, 3455, 3678, 4015, 4041, 4149, 4163], 'Claypool,': [194], 'R.': [195, 469, 1032, 1060, 1151, 1333, 1437, 1447, 1480, 1495, 1600, 2178, 2281, 2308, 2325, 2355, 2389, 2584, 2721, 2797, 2910, 3286, 3408, 3652, 4123, 4309, 4553, 4672, 4800, 4806], 'Kotzin,': [198], 'B.': [199, 332, 517, 800, 815, 1271, 1339, 1375, 1413, 1663, 1725, 1803, 1823, 1899, 1941, 1980, 1981, 2825, 3177, 3308, 3613, 3864, 3990, 4067, 4308, 4606, 4633, 4640, 4811], 'L.': [200, 447, 480, 486, 557, 642, 672, 696, 699, 792, 905, 1109, 1455, 1638, 1657, 1721, 1747, 1779, 1942, 2168, 2443, 2483, 2518, 2540, 2585, 2879, 2907, 3532, 3656, 3722, 3760, 3801, 3953, 3989, 4071, 4148, 4167, 4264, 4400, 4423, 4446, 4669], '(1985).': [201, 452, 1496, 2020, 2228, 2590, 2762, 4028], 'Weekly': [202], 'pulse': [203], 'methotrexate': [204], 'rheumatoid': [206, 3188, 3221, 3560], 'arthritis.': [207, 3222], 'immunologic': [210], 'effects': [211, 962, 3073, 3105, 4272], 'randomized,': [214], 'double-blind': [215, 3563], 'study.': [216, 716, 2696, 3670], 'Ann.': [217, 1766, 2340], 'Int.': [218, 2341], 'Med.,': [219, 781, 1326, 1768, 2031, 2277, 2342, 2614, 2926, 3444, 4259], '103,': [220, 4083], '489–496.': [221], 'Angus,': [222], 'P.,': [223, 745, 892, 900, 1148, 1368, 2380, 2382, 2722, 2791, 2932, 3128, 3202, 4690, 4729, 4764, 4798], 'Snook,': [224], 'Reid,': [227], 'M.': [228, 483, 512, 706, 742, 842, 902, 1035, 1177, 1250, 1299, 1330, 1365, 1407, 1440, 1629, 1633, 1637, 1702, 1724, 1860, 1935, 2294, 2314, 2416, 2662, 2727, 2733, 3130, 3289, 3363, 3386, 3485, 3531, 3751, 3754, 3792, 3795, 3827, 3925, 4043, 4268, 4524, 4559, 4566, 4605], 'D.': [231, 257, 281, 450, 451, 838, 877, 1067, 1091, 1095, 1154, 1184, 1490, 1536, 1561, 1634, 1660, 2038, 2056, 2079, 2103, 2106, 2124, 2148, 2284, 2295, 2311, 2589, 2704, 2882, 2934, 2976, 2980, 2984, 3065, 3069, 3431, 3528, 3578, 3605, 3612, 3718, 3726, 3833, 3972, 4026, 4047, 4609, 4775], '(1992).': [233, 1156, 1186], 'Oral': [234], 'fluticasone': [235], 'propionate': [236], 'active': [238, 319, 774, 918, 1021, 1223, 1355, 1872, 2714, 2957, 3216, 3419, 3590, 3842, 4031, 4496, 4543, 4788, 4821], 'distal': [239, 1224, 1712, 1787, 2772, 4053], 'Gut,': [242, 300, 381, 570, 859, 921, 1084, 1105, 1170, 1201, 1513, 1894, 2096, 2577, 2650, 2697, 2774, 2811, 2853, 3052, 3082, 3633, 3671, 3742, 3783, 4548, 4724, 4759], '(in': [243, 1171, 1202], 'press).': [244, 1172, 1203], 'Austin,': [245], 'Cann,': [248, 3647], 'Jones,': [251, 397, 428, 2631, 3012], 'T.': [252, 359, 391, 446, 1444, 1494, 1750, 1754, 1776, 1929, 1938, 2290, 2320, 2358, 2581, 3407, 4007], 'Holdsworth,': [255, 3644], '(1984).': [258, 334, 1380, 2420, 3486, 4049, 4196], 'Exacerbation': [259], 'diarrhoea': [261], 'pain': [263], 'patients': [265, 630, 916, 995, 1019, 1397, 1428, 2043, 2187, 2267, 2334, 2433, 2563, 2848, 2896, 3102, 3818, 4320, 4534, 4579], 'treated': [266, 2188], '5-aminosalicylic': [268, 519, 882, 910, 967, 987, 1015, 1236, 1348, 1391, 1425, 1782, 2063, 2111, 2234, 2454, 2554, 2744, 3239, 3270, 3294, 3323, 3415, 4317, 4529, 4571, 4575, 4778], 'Lancet,': [273, 324, 439, 810, 829, 942, 1000, 1433, 2376, 2536, 2673, 2717, 3026], 'i,': [274, 440, 811, 1001, 2377, 2674, 3027], '917–918.': [275], 'Khan,': [276, 303], 'Azad': [277, 304], 'Howes,': [280], 'T.,': [282, 510, 747, 1978, 2349, 3124, 3549, 4235, 4283, 4463], 'Piris,': [283, 307, 4691], 'Truelove,': [286, 310, 1882, 2127, 4330, 4355, 4372, 4395, 4418, 4441, 4694, 4716, 4739, 4770], '(1980).': [289, 1456, 2258, 4525], 'Optimum': [290, 907], 'dose': [291, 939, 3938], 'sulphasalazine': [293, 1047, 1388, 3041, 3219, 3620, 3660, 3772, 3813, 4494, 4819], 'maintenance': [295, 2091, 2666, 3021, 3144, 3815], 'treatment': [296, 343, 402, 563, 606, 626, 971, 1506, 1710, 1810, 1833, 2092, 2239, 2646, 2667, 2711, 2806, 2955, 2992, 3321, 3514, 3588, 3775, 3816, 3840, 3915, 4051, 4253, 4298, 4786], '21,': [301, 4549, 4725], '232–240.': [302], '(1977).': [313, 4674], 'An': [314, 821], 'experiment': [315], 'determine': [317, 3214, 4541], 'therapeutic': [320, 2140, 4348, 4411, 4434, 4544, 4754], 'moiety': [321, 3217, 4545], 'SASP.': [323, 999, 1432, 2046, 3110, 4547], 'ii,': [325, 830, 943, 1434], '892–895.': [326], 'Baioco,': [327], 'Korelitz,': [331], 'I.': [333, 655, 863, 1181, 3097, 3123, 3232], 'The': [335, 1809, 3072, 3369, 3487, 4499, 4698], 'influence': [336], 'disease': [340, 374, 497, 1162, 1192, 2367, 3436, 3517, 4502], 'its': [342, 1199, 1283, 1522, 2066, 2264, 3043, 3397, 4205], 'on': [344, 1137, 1673, 2137, 2458, 2600, 2918, 3045, 3244, 3252, 3350, 3492, 3621, 4207, 4221, 4345, 4409, 4432], 'pregnancy': [345], 'fetal': [347], 'outcome.': [348], 'clin.': [350, 1259, 1360, 1402, 2162, 2902, 3279, 3522, 3846, 4109], 'Gastroenterol,': [351], '6,': [352], '211–216.': [353], 'Banerjee,': [354], 'K.': [356, 443, 545, 872, 1115, 1249, 1265, 1296, 1340, 1376, 1414, 1451, 2221, 2226, 2257, 2324, 2446, 2486, 2525, 2550, 2862, 3172, 3432, 3651, 4044, 4267, 4590], 'Peters,': [358, 2732], '(1990).': [361, 878, 1116, 1141, 1665, 1947, 2058, 2108, 2296, 2706, 2883, 3835], 'Experimental': [362], 'nonsteroidal': [363], 'anti-inflammatory': [364], 'drug-induced': [365], 'enteropathy': [366], 'rat:': [369], 'similarities': [370], 'effect': [376, 2399, 3243, 3488, 4699], 'thromboxane': [378], 'synthetase': [379, 1889], 'inhibitors.': [380], '31,': [382, 2578], '1358–1364.': [383], 'Baron,': [384, 418, 3008], 'Connell,': [387, 421, 2660, 3005], 'M.,': [389, 423, 890, 898, 925, 946, 979, 1004, 1266, 1297, 1691, 1697, 1774, 1855, 2351, 2353, 2543, 3007, 3058, 3713, 4515, 4766], 'Karaghinis,': [390], 'Lennard-Jones,': [393, 424, 844, 1983, 2201, 2617, 2653, 2676, 2759, 2785, 3002, 3450, 4239], 'E.': [395, 426, 579, 846, 1210, 1334, 1558, 1755, 1807, 1977, 2203, 2629, 2761, 2819, 3680, 3973, 4097, 4234, 4241, 4591], 'Avery': [398, 429, 2632, 3013], 'F.': [399, 430, 750, 952, 1533, 1968, 2006, 2633, 2737, 2859, 3014, 3331, 4094, 4465], '(1962a).': [400], 'Outpatient': [401], 'Comparision': [406], 'between': [407, 3183], 'three': [408, 1125, 2559, 4659], 'doses': [409], 'oral': [411, 1352, 1424, 1502, 1867, 2238], 'prednisolone.': [412], 'Br.': [413, 884, 1358, 1400, 1651, 2142, 2192, 2213, 2873, 3163, 3192, 3277, 3325, 3478, 3572, 3596, 4034, 4350, 4367, 4390, 4413, 4436, 4455], 'med.': [414, 885, 1652, 2143, 2193, 2214, 2874, 3164, 3193, 3326, 3479, 3573, 3597, 4035, 4351, 4368, 4391, 4414, 4437, 4456, 4597], 'J.,': [415, 508, 539, 550, 697, 721, 785, 886, 1331, 1335, 1366, 1408, 1438, 1481, 1484, 1653, 1658, 1689, 1772, 1847, 1933, 1939, 1946, 1972, 2144, 2169, 2194, 2215, 2285, 2312, 2321, 2414, 2521, 2622, 2728, 2781, 2829, 2875, 3001, 3088, 3092, 3117, 3121, 3165, 3194, 3327, 3449, 3480, 3574, 3598, 3752, 3793, 3855, 4036, 4121, 4151, 4155, 4352, 4369, 4392, 4415, 4438, 4457, 4471], '2,': [416, 1654, 2195, 2876, 3195, 3575, 4353, 4393, 4416, 4439, 4586], '441–443.': [417], '(1962b).': [431], 'Sulphasalazine': [432, 1252, 3558, 4099, 4197, 4612], 'salicylazosulpha-': [434], 'dimadine': [435], '1094–1096.': [441], 'Barrett,': [442, 1805], 'E.,': [444, 548, 1985, 2222, 2384, 2619, 2655, 2678, 2787, 2789, 3004, 3452, 3716, 3755, 3796, 4801], 'Tachof,': [445], 'Metcalfe,': [449], 'Inhibition': [453, 1886, 2739, 3729], 'Ig': [455], 'E': [456], 'mediated': [457], 'mast': [458, 3343, 3356, 3996], 'call': [459], 'degranulation': [460], 'sulphasalazine.': [462], 'Eur.': [463], 'Pharmac.,': [465, 1361, 1403, 3280, 4211], '107,': [466], '279–281.': [467], 'Bear,': [468], '(1976).': [470, 3463], 'Pregnancy': [471, 2021], 'lupus': [473], 'nephritis.': [474], 'Obstet.': [475], 'Gynecol.,': [476], '47,': [477], '715–718.': [478], 'Bernstein,': [479, 698], 'Frank,': [482, 705], 'Brandt,': [485, 695], 'Boley,': [489, 701], '(1981).': [492, 932], 'Healing': [493], 'perianal': [495], "Crohn's": [496, 568, 712, 776, 2159, 2272, 3516, 4497, 4501], 'metronidazole.': [499], '79,': [501, 1477], '357–365.': [502], 'Biddle,': [503], 'W.': [504, 639, 669, 1063, 1176, 1275, 1307, 1806, 2628, 2683, 2736, 3094, 3462, 3826, 3909, 4014, 4040, 4070, 4093, 4114, 4126, 4143, 4189, 4565], 'L.,': [505, 537, 543, 723, 787, 1745, 1851, 2755, 2930, 2943, 3332, 3852, 4165, 4629], 'Greenberger,': [506], 'Swan,': [509], 'McPhee,': [511], 'Miner,': [515], '(1988).': [518, 1562, 1580, 1726, 1756, 2081, 2490, 3233, 3317, 3537, 3579, 3883, 3991, 4216, 4567, 4812], 'enemas:': [521], 'effective': [522, 3887], 'agent': [523, 4755], 'maintaining': [525, 1991, 3891], 'remission': [526, 1992, 2332, 3143], 'left-sided': [528, 1759, 1812], '94,': [532, 1741, 3112, 3546, 3823], '1075–1079.': [533], 'Binder,': [534, 573, 759, 798, 3685, 3858], 'V.,': [535, 574, 3198, 3686, 3749, 3790], 'Elsborg,': [536], 'Greibe,': [538], 'Hendriksen,': [540], 'C.,': [541, 743, 864, 867, 896, 1178, 1448, 2224, 2625, 3170, 3204, 3639, 3643, 3720, 3828, 4374, 4603], 'Hoj,': [542], 'Jensen,': [544], 'B.,': [546, 552, 793, 1146, 1174, 1800, 1845, 1849, 1927, 1965, 2751, 2779, 2977, 3284, 3857, 4161, 4461, 4473, 4481], 'Kristensen,': [547], 'Rask-Madsen,': [549, 2418, 2448, 2488, 2527, 2546, 4150], 'Marner,': [551], 'Riis,': [553, 762], 'Willumsen,': [556], '(1981b).': [558], 'Disodium': [559], 'cromoglycate': [560, 853], 'colitis': [566, 806, 936, 994, 1422, 1584, 1610, 1761, 1814, 1836, 2157, 2270, 2670, 3666, 3739, 3781, 3893, 4055, 4337, 4676, 4721], '22,': [571, 1229, 2050], '55–60.': [572], 'Halskov,': [575, 3687], 'Hvidberg,': [578, 3679], '(1981a).': [580], 'A': [581, 714, 765, 848, 954, 1037, 1212, 1911, 2082, 2229, 3211, 3667, 3866, 4128, 4172, 4343, 4488], 'controlled': [582, 849, 1126, 1213, 1499, 1957, 2083, 2139, 2504, 2968, 3867, 4347], 'study': [583, 1865, 2183, 3212, 4490, 4503, 4539], '5-acetaminosalicylic': [585], 'as': [587, 912, 989, 1075, 1466, 1504, 2644, 2665, 3472, 3814, 3886, 3888, 4245, 4647], 'enema': [588, 914, 991, 2770, 3475, 4782], 'Scand.': [592, 612, 1226, 1592, 2047, 2510, 3946, 4085, 4707, 4824], 'gastroenterol.,': [594], '16,': [595, 1362, 2698, 3281], '1112.': [596], 'Bjork,': [597, 617], 'Dahlstrom,': [599, 619], 'Ahlman,': [602, 622], 'Topical': [605, 625, 1117, 1235, 4050], 'proctitis': [609], 'lidocaine.': [611], 'Gastroenterol.,': [614, 1228, 1594, 1795, 2049, 2512, 3847, 3948, 4087, 4230, 4709, 4793, 4826], '24,': [615, 1895], '1061–1072.': [616], '(1991).': [624, 906, 1097, 1537, 1986, 2007, 2830, 2949, 3433, 3615, 3954, 4310], 'lidocaine': [628], '100,': [635, 1551, 2001, 2971, 4140, 4186], 'A198.': [636], 'Bland,': [637, 667], 'Warren,': [641, 671], '(1986a).': [644], 'Antigen': [645, 675], 'presentation': [646, 676], 'epithelial': [648, 678, 2117, 2893, 2920], 'cells': [649, 679, 2890, 2894, 2921, 3344, 3997], 'rat': [652, 682, 4622], 'small': [653, 683], 'intestine': [654], 'Kinetics,': [656], 'antigen': [657], 'specificity': [658], 'blocking': [660], 'anti-la': [662], 'antisera.': [663], 'Immunology,': [664, 692], '58,': [665, 693], '1–7.': [666], '(1986b).': [674], 'intestine.': [684], 'II.': [685, 3345, 4218], 'Selective': [686, 2530], 'induction': [687, 2886], 'suppressor': [689, 2888], 'T': [690, 2889], 'cells.': [691, 2118, 3357], '9–14.': [694], '(1982).': [708, 2204, 2359, 3341, 3692, 3728, 4098, 4487, 4742], 'Metronidazole': [709], 'follow-up': [715], '83,': [718, 3709, 4231, 4509], '383–387.': [719], 'Brynskov,': [720, 784], 'Freund,': [722, 786], 'Rasmussen,': [724, 794, 3674], 'N.,': [726, 734, 833, 1089, 1337, 1975, 3676], 'Lauritsen,': [727, 2411, 2440, 2480, 2524, 2549, 4145], 'Schaffalitzky': [729], 'de': [730], 'Muckadell,': [731], 'O.,': [732, 756, 790], 'Williams,': [733, 2587], 'MacDonald,': [735], 'Tanton,': [737], 'Molina,': [739], 'F.,': [740, 1556, 2753, 3681, 4115, 4144, 4190, 4286], 'Camparini,': [741], 'Bianchi,': [744], 'Ranzi,': [746], 'di': [748], 'Palo,': [749], 'Q.,': [751], 'Malchow-Møllet,': [752], 'Thomsen,': [754, 788, 4290], 'O.': [755, 789, 1604, 3228, 3262, 4153, 4483, 4737], 'Tage-Jensen,': [757, 4280], 'V.': [760, 799, 1576, 2287, 2317, 3169, 3180, 4637], '(1989a).': [764], 'placebo-controlled,': [766], 'double-blind,': [767], 'randomized': [768], 'trial': [769, 850, 958, 1071, 1215, 1458, 1500, 1728, 2084, 2206, 2800, 3017, 3868, 4129, 4174], 'cyclosporin': [771, 808, 2709], 'chronic': [775, 855, 2025, 2210, 3875, 4300], 'New': [778, 1323, 2028, 2274, 2611, 3441, 4311], 'Engl.': [779, 1324, 2029, 2275, 2612, 3442], '321,': [782], '845–850.': [783], 'Andersen,': [791], '(1989b).': [801], 'Treatment': [802, 933, 1419, 1581, 1607, 1757, 4334], 'refractory': [804, 1786, 1835, 2336, 3542], 'enemas.': [809, 941, 1613, 1765, 1839, 4058], '721–722.': [812], 'Bryan,': [813], 'Phillida,': [817], '(1964).': [820], 'indication': [822], 'surgery': [824], 'acute': [826, 1474, 1508], '1272–1273.': [831], 'Buckall,': [832], 'Gould,': [834, 4802], 'Day,': [837], 'Edwards,': [840, 1937], '(1978).': [847], 'disodium': [852, 4750], 'persistent': [856], '19,': [860], '1140–1143.': [861], 'Calder,': [862], 'Funder,': [865], 'Green,': [868], 'Ham,': [871], 'Tange,': [875], 'Nephrotoxic': [879], 'lesions': [880], 'from': [881, 1350, 2765, 2847, 2895], 'acid.': [883, 2745, 3324], '1,': [887, 2651, 3481, 4370, 4458], '152–154.': [888], 'Campieri,': [889, 924, 945, 978, 1003, 4765], 'Gionchetti,': [891], 'Belluzzi,': [893], 'Brignola,': [895, 984, 1009], 'Tampieri,': [897], 'Iannone,': [899], 'Miglioli,': [901], 'Barbara,': [904], 'dosage': [908, 3300], 'rectal': [913, 990, 1892], '32,': [922, 1106, 1246, 1717, 2854, 3634], '929–931.': [923], 'Lanfranchi,': [926, 947, 980, 1005, 4767], 'Bazzocchi,': [930], 'high': [938], '5-ASA': [940, 1232, 1838], '270–271.': [944], 'Bertoni,': [951], '(1984b).': [953], 'double': [955, 3668], 'blind': [956, 1039, 1498, 3669, 4814], 'clinical': [957, 1621, 1958, 2329, 4173], 'compare': [960], '4-aminosalicylic': [964, 1763], 'topical': [970, 2453, 2640, 4251, 4701], 'Digestion,': [975, 4059], '29,': [976, 1027, 2097, 3784, 4060], '204–208.': [977], '(1984a).': [986], 'unable': [996, 1429], 'take': [998, 1431], '403.': [1002], '(1986).': [1011, 1069, 1808, 2450, 2798, 3210, 3910, 4777], 'Retrograde': [1012, 1640, 2865], 'spread': [1013, 1641, 2867], 'enemas': [1017, 1221, 1707, 1784, 2362, 3160], 'Dis.': [1024, 1244, 1623, 1715, 4276], 'Colon': [1025, 1624], 'Rectum,': [1026, 1625], '108–110.': [1028], 'Caprilli,': [1029], 'Carratu,': [1031], 'Babbini,': [1034], '(1975).': [1036, 2688, 3865], 'double-': [1038], 'comparison': [1040, 2567, 3136, 3564, 4569, 4815], 'effectiveness': [1043], 'azathioprine': [1045, 1989, 2208, 3870, 4297], 'idiopathic': [1049, 4536, 4581], 'protocolitis:': [1050], 'Preliminary': [1051, 2707, 4407], 'report.': [1052], 'Am.': [1053, 1793, 4228], 'Dig.': [1055, 1243, 1714, 4275], 'Dis.,': [1056], '20,': [1057], '115–120.': [1058], 'Chapman,': [1059, 3530], 'Selby,': [1062, 4013, 4039], 'Controlled': [1070, 1457, 2205, 2799, 3016], 'intravenous': [1073, 1460, 2991], 'metronidazole': [1074, 4492], 'an': [1076, 1351, 1467, 4246], 'adjunct': [1077, 1468], 'corticosteroids': [1079], 'severe': [1081, 1102, 1734, 2713, 2808], '27,': [1085, 2812], '1210–1212.': [1086], 'Chew,': [1087], 'Noland,': [1090], 'Small': [1098, 1277], 'gas': [1100], '1535–1537.': [1107], 'Christensen,': [1108], 'Fallingborg,': [1111], 'Abildgaard,': [1114], 'systemic': [1119, 2397], 'availability': [1120], '5-aminosalicylate:': [1122], 'comparisons': [1123], 'release': [1127, 1346, 3699, 3766, 3807], 'preparations': [1128, 2561], 'man.': [1130, 2923, 3276, 3982], 'Aliment.': [1131, 2013, 3302, 4325, 4583], 'Pharmac.': [1132, 1683, 2014, 2407, 3303, 3380, 3984, 4326, 4584], 'Ther.,': [1133, 1685, 2015, 2408, 3304, 3382, 3985, 4327, 4585], '4,': [1134, 2145], '523–533.': [1135], 'Committee': [1136], 'Safety': [1138], 'Medicines': [1140], 'Current': [1142], 'Problems,': [1143], '30.': [1144], 'Hoang,': [1147], 'Dalton,': [1149], 'Salicylates': [1157, 1187], 'used': [1158, 1188, 2643], 'colchicine': [1164], 'impair': [1165], 'Interferon-γ': [1166], 'induced': [1167, 4618], 'HLA-DR': [1168], 'expression.': [1169], 'Rosenberg,': [1175, 2938, 3825, 3850], 'Bell,': [1179], '(IBD)': [1193], 'inhibit': [1194], 'binding': [1195, 4200], 'IFN-γ': [1197], 'receptor.': [1200], 'Danielsson,': [1204], 'Hellers,': [1206], 'Lyrenas,': [1209], '(1987).': [1211, 1234, 1703, 1781, 1828, 2040, 2911, 3038, 3071, 4293, 4641], 'randomised': [1214, 3594], 'budesonide': [1217], 'versus': [1218, 1238, 2987, 3584], 'prednisolone': [1219, 1239, 2457, 2769, 3157, 3465, 3470], 'retention': [1220, 1706, 3159, 3474], '987–992.': [1230], 'Danish': [1231], 'Group': [1233], 'protosigmoiditis.': [1242], 'Sci.,': [1245, 1716, 2069, 2120, 3427, 4277], '598–602.': [1247], 'Das,': [1248, 1264, 1295, 4266], 'Gastro.': [1258, 2161, 3521], 'Nth.': [1260], 'Am.,': [1261, 2164, 3524], '18,': [1262, 2165, 3525, 3949, 4794], '1–20.': [1263], 'Chowdhury,': [1267], 'Zapp,': [1270], 'Fara,': [1273], '(1979).': [1276, 1639, 2179, 3409], 'absorption': [1279, 1384, 3628, 4074], 'SASP': [1281, 2088, 2262, 3019, 3186, 3566, 3585, 3889, 4385], 'hepatic': [1284], 'metabolism': [1285, 1319, 1386, 2423, 2497, 3247, 3376, 3413, 3976, 4745], 'human': [1287, 1891, 2115, 3249, 3497, 3631, 3995, 4208, 4747], 'beings,': [1288], 'cats': [1289], 'rats.': [1291, 3424], '77,': [1293], '280–284.': [1294], 'Eastwood,': [1298], 'McManus,': [1301], 'Sircus,': [1306], '(1973).': [1308, 3391], 'Adverse': [1309], 'reactions': [1310], 'during': [1311], 'salicylazosulfapyridine': [1312, 3980], 'relation': [1316], 'drug': [1318], 'acetylator': [1321], 'phenotype.': [1322], '289,': [1327], '491–495.': [1328], 'Dew,': [1329, 1364, 1406], 'Ryder,': [1332], 'Evans,': [1336, 1338, 1374, 1412], 'Rhodes,': [1342, 1378, 1416, 3711], '(1983a).': [1344], 'preparation': [1353], '185–187.': [1363], 'Ebden,': [1367], 'Kidwai,': [1369], 'Lee,': [1372, 2580], 'Comparison': [1381, 3182, 3763, 3804, 4381], 'acrylic-coated': [1390], 'normal': [1394, 3630], 'subjects': [1395, 3943], '17,': [1404], '474–476.': [1405], 'Harries,': [1409], 'D.,': [1411, 2315, 2820, 2941, 3060, 3063, 3335, 3646, 4018, 4117, 4157], '(1983b).': [1418], '801.': [1435], 'Dickinson,': [1436, 1479], 'Ashton,': [1439], 'Axon,': [1442, 1492], 'Smith,': [1446], 'Yeung,': [1449], 'Hill,': [1453, 3205], 'hyperalimentation': [1461], 'total': [1463], 'rest': [1465, 2803], 'routine': [1471], '1199–1204.': [1478], "O'Connor,": [1482], 'Pinder,': [1485], 'I.,': [1486, 1488, 4467], 'Hamilton,': [1487], 'Johnson,': [1489], 'Double': [1497, 4813], 'vancomycin': [1503], 'adjunctive': [1505], 'exacerbations': [1509], '26,': [1514, 2775], '1380–1384.': [1515], 'Dinarello,': [1516], 'Interleukin-1': [1520], 'biologically': [1523], 'related': [1524], 'cytokines.': [1525], 'Adv.': [1526], 'Immunol.,': [1527, 3359], '44,': [1528], '153–205.': [1529], 'Eliakim,': [1530, 1553], 'Karmeli,': [1532, 1555], 'Rachmilewitz,': [1535, 1560, 3577], 'Ketotifen': [1538], '(K)': [1539], 'effectively': [1540], 'prevents': [1541], 'mucosal': [1542, 4619], 'damage': [1543, 4653], 'two': [1545], 'models': [1546], 'experimental': [1548, 3738], 'A578.': [1552], 'Razin,': [1557], 'Role': [1563], 'platelet-activating': [1565], 'factor': [1566, 4248, 4646, 4662], '95,': [1571, 3149], '1167–1172.': [1572, 3054], 'Ewe,': [1573], 'Eckardt,': [1575], 'Kanzler,': [1578], 'olsalazine': [1586, 2086, 2496, 2557, 3075, 3618, 4817], 'sulphasalazine:': [1588], 'efficacy': [1589, 1917, 2260], 'side-effects.': [1591], '23': [1595, 2513, 4088, 4827], '(Suppl.': [1596, 2514, 4089, 4828], '148),': [1597, 2515, 4090, 4829], '70–75.': [1598, 4091], 'Farmer,': [1599], 'Schumacher,': [1603], '(1970).': [1606], 'hydrocortisone': [1612, 1616, 1643, 2641, 2988, 4340], 'Relationship': [1614], 'absorption,': [1617], 'adrenal': [1618], 'suppression': [1619], 'response.': [1622], '13,': [1626, 3225, 3986], '355–361.': [1627], 'Farthing,': [1628, 1690], 'Rutland,': [1632], 'Clark,': [1636], 'containing': [1644], 'foam': [1645], 'given': [1646], 'intrarectally': [1647], '822–824.': [1655], 'Fretland,': [1656], 'Widomski,': [1659], 'Tsai,': [1662], 'Effect': [1666, 2591, 2950, 3039, 3616, 4526], 'leukotriene': [1668, 2462, 2606, 3493], 'B4': [1669, 2463], 'receptor': [1670, 4206], 'antagonist': [1671], 'SC-41930': [1672], 'colonic': [1674, 2116, 2866], 'inflammation': [1675], 'rat,': [1677], 'guinea': [1678], 'pig': [1679], 'rabbit.': [1681], 'exp.': [1684, 2925, 3381, 4080], '255,': [1686], '572–576.': [1687], 'Gandolfo,': [1688], 'Power,': [1692], 'Eagen,': [1694], 'Goldberg,': [1696, 2978], 'Berman,': [1698], 'Kaplan,': [1701], '4-amino-salicylic': [1704], '700–704.': [1718], 'Ginsberg,': [1719, 1743], 'Albert,': [1723], 'Pilot': [1727], 'enteric': [1730], 'coated': [1731], '4-ASA': [1732, 4057], 'steroid': [1735], 'dependent': [1736], 'A147.': [1742], 'Beck,': [1746], 'McIntosh,': [1749], 'Nochomowitz,': [1753], 'int.': [1767], '108,': [1769], '195–199.': [1770], 'Guarino,': [1771], 'Chatzinoff,': [1773], 'Berk,': [1775], 'Friedman,': [1778], 'Long': [1790], 'term': [1791], 'results.': [1792], '82,': [1796], '732–737.': [1797], 'Hanauer,': [1798, 1821, 1843, 4162], 'Kirsner,': [1801, 3862, 4065], 'tixocortol': [1816], 'pivalate.': [1817], '90,': [1819, 3920], '1449.': [1820], 'Schultz,': [1825], 'Relapse': [1829], 'rates': [1830], 'after': [1831, 2400, 3272, 3320, 3467], 'successful': [1832, 4250], '92,': [1841], '1424.': [1842], 'Schwarz,': [1846], 'Guernsey,': [1848], 'Beshears,': [1850], 'Roufail,': [1852], 'Robinson,': [1854], 'Cello,': [1856], 'Safdi,': [1859], 'Open-label': [1862], 'Dose': [1863], 'ranging': [1864], 'mesalamine': [1868], 'capsules': [1869], '(Pentasa)': [1870, 4780], '96,': [1876, 2747, 4625], 'A195.': [1877], 'Hawkey,': [1878, 1901, 1931, 1970, 2827], '(1983).': [1885, 2390, 2985, 3181, 3267, 3557, 3929, 4269], 'prostaglandin': [1888, 2459, 2492], 'mucosa.': [1893], '213–217.': [1896], 'Hawthorne,': [1897, 1925, 1963, 2823], 'Immunosuppressive': [1905], 'drugs': [1906], 'their': [1914, 3962], 'mechanisms': [1915], 'place': [1919], 'therapy.': [1921], 'Drugs,': [1922], '38,': [1923], '267–288.': [1924], 'Daneshmend,': [1928], 'Shaheen,': [1934], 'Z.,': [1936, 3311], 'Filipowicz,': [1940], 'Everitt,': [1944], 'Fish': [1948], 'oil': [1949, 4132], 'colitis:': [1952, 1995, 2134, 2501, 2566, 2693, 2959, 3592], 'final': [1953, 2135], 'results': [1954, 2960], 'trial.': [1959, 1999, 2141, 2969, 3191, 3595, 4349, 4412, 4435], '98,': [1961, 2305], 'A174.': [1962], 'Logan,': [1966], 'Foster,': [1973], 'Swarbrick,': [1976, 4233], 'Scott,': [1979], 'Efficacy': [1987, 3538], 'placebo-controlled': [1997], 'withdrawal': [1998], 'A216.': [2002], 'Hodgson,': [2003], 'Cyclosporin': [2008], '5,': [2016, 4328], '343–350.': [2017], 'Hou,': [2018], 'women': [2023], 'renal': [2026], '312,': [2032, 2615], '836–839.': [2033], 'Ireland,': [2034, 2052, 2072, 2099, 3829, 4019], 'Olsalazine': [2041, 3658, 4029], 'intolerant': [2044], '1038–1040.': [2051], 'Mechanism': [2059], 'action': [2061], 'derivatives.': [2067], 'Clin.': [2068, 2119, 2406, 3983], '78,': [2070, 2121], '119–125.': [2071], 'Mason,': [2074, 4021], 'comparing': [2085], '835–837.': [2098], 'Priddle,': [2101, 3061], 'Acetylation': [2109], 'isolated': [2114, 3354], '105–111.': [2122], '(1974).': [2130, 4242], 'Azathioprine': [2131], 'report': [2136, 4344, 4408, 4431], '627–630.': [2146], 'Corticosteroids': [2151], 'management': [2154, 3873], 'Nth': [2163, 3523], '21–34.': [2166], 'Kinlen,': [2167], 'Shiel,': [2170], 'Peto,': [2174], 'Doll,': [2177], 'Collaborative': [2180], 'United': [2181], 'Kingdom-Australian': [2182], 'cancer': [2185], 'immunosuppressive': [2190, 3510, 3963], 'drugs.': [2191], '1461–1466.': [2196], 'Kirk,': [2197], '284,': [2216], '1291–1292.': [2217], 'Maier,': [2220, 2251], 'Fischer,': [2223, 2253], 'Bauer,': [2225], 'new': [2230], 'slow-release': [2231, 3138], 'form': [2232, 4783], 'Arzneim-Forsch.': [2244], 'Res.,': [2246], '35,': [2247], '636–639.': [2248], 'Klot,': [2249], 'Heinkel,': [2256], 'Therapeutic': [2259, 2763], 'metabolites': [2265, 3044, 4613], '303,': [2278], '1499–1502.': [2279], 'Kozarek,': [2280, 2307], 'Patterson,': [2283, 2310], 'Botoman,': [2286, 2316], 'Ball,': [2289, 2319], 'Gelford,': [2293, 2313], 'Methotrexate:': [2297], 'long': [2299, 2508], 'short': [2301], 'it.': [2303], 'A183.': [2306], 'Wilske,': [2323], 'Methotrexate': [2327], 'induces': [2328], 'histologic': [2331], '110,': [2343], '353–356.': [2344], 'Kumana,': [2345], 'Seaton,': [2348], 'Meghji,': [2350], 'Castelli,': [2352], 'Benson,': [2354], 'Sivakumaran,': [2357], 'Beclamethasone': [2360], 'diproprionate': [2361], 'treating': [2364], 'without': [2368], 'producing': [2369], "Cushing's": [2370], 'syndrome': [2371, 3319], 'or': [2372, 3106, 3251, 3659], 'hypothalamic': [2373], 'pituitary': [2374], 'suppression.': [2375], '579–583.': [2378], 'Larochelle,': [2379], 'DuSonich,': [2381], 'Bolte,': [2383], 'Lelorier,': [2385], 'Goyer,': [2388], 'Tixocortol': [2391], 'pivalate,': [2392], 'corticosteroid': [2394, 4252, 4362, 4383], 'no': [2396, 3242], 'glucocorticoid': [2398], 'oral,': [2401], 'intrarectal': [2402], 'intranasal': [2404], 'application.': [2405], '33,': [2409, 4212], '343–50.': [2410], 'Hansen,': [2413, 3682], 'Ryde,': [2415, 3924], 'azodisalicylate': [2422], 'determined': [2424, 2465], 'vivo': [2427, 2469], 'dialysis': [2428, 2470], 'healthy': [2430], 'volunteers': [2431, 4748], '86,': [2438, 2904], '1496–1500.': [2439], 'Laursen,': [2442, 2482, 2517, 2539, 4147], 'Bukhave,': [2445, 2485, 2522, 2544], 'Effects': [2451, 3346, 4657], 'E2': [2460, 2493], 'levels': [2464, 2494, 3466], 'equilibrium': [2467], 'rectum': [2472], 'relapsing': [2474, 2499], '91,': [2478], '837–844.': [2479], 'implications': [2502], 'trials': [2505], 'term.': [2509], '76–80.': [2516], 'Naesdal,': [2520, 4154], '(1990b).': [2529], '5-lipoxygenase': [2531, 4181], 'inhibition': [2532], '335,': [2537], '683–685.': [2538], 'Stokholm,': [2542], '(1990a).': [2551], 'Disposition': [2552], 'mesalazine': [2560, 3581], 'intraluminal': [2569], 'cononic': [2570], 'concentrations,': [2571], 'serum': [2572], 'values': [2573], 'urinary': [2575], 'excretion.': [2576], '1271–1276.': [2579], 'Hoover,': [2583], 'dietary': [2593], 'enrichment': [2594], 'eicosapentaenoic': [2596, 3490], 'docosa-hexaenoic': [2598], 'acids': [2599], 'vitro': [2602], 'neutrophil': [2603, 2609], 'monocyte': [2605], 'generation': [2607, 3047], 'function.': [2610], '1217–1224.': [2616], 'Longmore,': [2620], 'Newell,': [2623], 'Wilson,': [2626, 3456], '(1960).': [2634, 4072, 4358], 'Assessment': [2635, 2689], 'prednisone,': [2637], 'salazopyrin': [2638], 'hemisuccinate': [2642, 4341], 'out-patient': [2645], '217–222.': [2652], 'Misiewicz,': [2656, 2999], '(1965).': [2663, 3015], 'Prednisone': [2664], 'remission.': [2672, 3895], '188–189.': [2675], 'Ritchie,': [2679], 'Hilder,': [2682], 'Spicer,': [2685], 'severity': [2691], 'preliminary': [2695], '579–584.': [2699], 'Lichtiger,': [2700], 'Present,': [2703, 2933, 3504, 3527], 'report:': [2708], '336,': [2718], '16–19.': [2719], 'MacDermott,': [2720], 'Schloemann,': [2723], 'Bertovich,': [2726], 'Nash,': [2729], 'Stenson,': [2735, 4092, 4113, 4142, 4188], 'antibody': [2741], 'secretion': [2742, 3352], '442–448.': [2748], 'McIntyre,': [2749, 2777], 'Macrae,': [2752], 'Berghouse,': [2754], 'English,': [2756], 'benefits': [2764], 'poorly': [2767], 'absorbed': [2768], '822–825.': [2776], 'Powell-Tuck,': [2780, 3448], 'Wood,': [2782], 'Lerebours,': [2788], 'Hecketsweiler,': [2790], 'Galmiche,': [2792], 'Colin,': [2796], '481–485.': [2813], 'Mahida,': [2814], 'Y.': [2815, 3037], 'Lamming,': [2817], 'Gallagher,': [2821], '5-Aminosalicylic': [2831], 'is': [2833, 3885], 'potent': [2835], 'inhibitor': [2836, 4179], 'interleukin': [2838], '1β': [2839], 'production': [2840, 3495], 'organ': [2842], 'culture': [2843], 'biopsy': [2845], 'specimens': [2846], '50–54.': [2855], 'Matts,': [2856], 'Gaskell,': [2861], '(1961).': [2864], 'enemata': [2869], '614–616.': [2877], 'Mayer,': [2878, 2906, 2929], 'Eisenhardt,': [2881], 'Lack': [2884], 'intestinal': [2892, 3355, 3372], 'Invest.,': [2903, 4110], '1255–1260.': [2905], 'Schlien,': [2909], 'Evidence': [2912, 4642], 'function': [2914], 'la': [2916], 'molecules': [2917], 'gut': [2919, 3411], '166,': [2927], '1471–1483.': [2928], 'Turtel,': [2931], 'Janowitz,': [2936, 2982], 'Sachar,': [2940, 2975], 'Mitchell,': [2942], 'Itzkowitz,': [2944], 'Martin,': [2947], 'hydroxychloroquine': [2952], 'open': [2963], 'label': [2964], 'phase': [2965], 'A230.': [2972], 'Meyers,': [2973], 'Corticotrophin': [2986], '85,': [2997], '351–357.': [2998], '185–188.': [3028], 'Miyachi,': [3029], 'Y.,': [3030], 'Yashioka,': [3031], 'Immamura,': [3033], 'Niwa,': [3036], 'reactive': [3049], 'oxygen': [3050], 'species.': [3051], '28,': [3053, 3083, 4278], 'Mohsen,': [3055], 'Q.': [3057], 'Mulvey,': [3059], 'Parsons,': [3064], 'jejunum': [3078], 'rat.': [3081, 4656], '346–352.': [3084], 'Mulder,': [3085, 3114], 'Tytgat,': [3089, 3118], 'Dekker,': [3093, 3125], 'Terpstra,': [3096], '(1988a).': [3098, 3762], 'Pentasa': [3099], '70': [3101], 'side': [3104], 'allergy': [3107], 'due': [3108], 'A313.': [3113], 'Weterman,': [3122], 'Blok,': [3127], 'Schrijver,': [3129], 'Heide,': [3132], '(1988b).': [3134, 3803], 'Double-blind': [3135, 4568], '5-aminosalicylate': [3139], 'sulfasalazine': [3141], '1449–1453.': [3150], 'Multicentre': [3151], 'Trial': [3152], '(1971).': [3153], 'Betamethasone': [3154], '17-valerate': [3155], '21-phosphate': [3158, 3471], 'proctocolitis.': [3162], '3,': [3166, 3305], '84–86.': [3167], 'Neumann,': [3168, 3197], 'Grindulis,': [3171], 'Hubball,': [3174], 'McConkey,': [3176], 'Wright,': [3179], 'penicillamine': [3184], 'arthritis:': [3189, 3561], 'Leeds-Birmingham': [3190], '1099–1102.': [3196], 'Taggart,': [3199], 'LeGallez,': [3201], 'Astbury,': [3203], 'Bird,': [3208], 'Rheumatol.,': [3224], '285–287.': [3226], 'Nielson,': [3227, 3261], 'Ahnfelt-Ronne,': [3231], '4-Aminosalicylic': [3234], 'acid,': [3235, 3240, 3416], 'constrast': [3237], 'has': [3241], 'arachidonic': [3245], 'neutrophils,': [3250], 'free': [3254], 'redical': [3255], '1,1-diphenyl-2-picrylhydrazyl.': [3256], 'Pharm.': [3257], 'Toxicol.,': [3258], '62,': [3259], '223–226.': [3260], 'Bondesen,': [3265, 3677], 'Kinetics': [3268], 'jejeunal': [3273], 'instillation': [3274], '738–740.': [3282], 'Norlander,': [3283], 'Gotthard,': [3285], 'Strom,': [3288], 'Pharmacokinetics': [3291], 'enteric-coated': [3296], 'tablet': [3297], 'suppository': [3299], 'form.': [3301], '333–342.': [3306], 'Novis,': [3307], 'Korzets,': [3310], 'Chen,': [3312], 'Bernheim,': [3315], 'Nephrotic': [3318], '296,': [3328], '1442.': [3329], 'Pearce,': [3330], 'Befus,': [3333], 'Gauldie,': [3336], 'Bienenstock,': [3339], 'Mucosal': [3342], 'anti-allergic': [3348], 'compounds': [3349], 'histamine': [3351], '128,': [3360], '2481–2486.': [3361], 'Peppercorn,': [3362, 3385], 'Goldman,': [3366, 3389], '(1972).': [3368, 3974], 'role': [3370], 'bacteria': [3373], 'salicylazosulphapyridine.': [3378], '181,': [3383], '555–562.': [3384], 'Distribution': [3392, 4743], 'studies': [3393], 'salicylazosulphapyridine': [3395], 'metabolites.': [3398], '64,': [3400], '240–245.': [3401], 'Pieniaszek,': [3402], 'Bates,': [3406], 'Capacity-limited': [3410], 'wall': [3412], 'therapeutically': [3418], 'metabolite': [3420], 'sulfasalazine,': [3422], 'pharm.': [3426], '68,': [3428], '1323–1325.': [3429], 'Podolsky,': [3430], 'Inflammatory': [3434], '(parts': [3437], '1': [3438, 3936], '2).': [3440], '325,': [3445], '928–937,': [3446], '1008–1016.': [3447], 'May,': [3453], 'Paterson,': [3460], 'Plasma': [3464], 'administration': [3468], '193–195.': [3482], 'Prescott,': [3483], 'neutrophils.': [3498, 4107, 4209], 'biol.': [3500], 'Chem.,': [3501], '259,': [3502], '7615–7621.': [3503], 'D.H.': [3505], '6-Mercaptopurine': [3507], 'other': [3509], 'agents': [3511], '57–71.': [3526], 'Rubin,': [3534, 4169], '6-mercaptopurine': [3540], 'A359.': [3547], 'Pullar,': [3548], 'Hunter,': [3550], 'Capell,': [3554], 'placebo': [3568, 4532], 'sodium': [3570, 3912, 3941], 'aurothiomalate.': [3571], '1102–1104.': [3576], 'Coated': [3580], '(5-aminosalicylic': [3582], 'acid)': [3583], '298,': [3599], '82–86.': [3600], 'Raimundo,': [3601], 'Patil,': [3604], 'Frost,': [3607], 'Silk,': [3611], 'jejunal': [3622], 'ileal': [3624], 'water': [3625], 'electrolyte': [3627], 'subjects.': [3632], '270–274.': [3635], 'Rao,': [3636], 'Dundas,': [3640], 'Palmer,': [3650, 4069], 'Corbett,': [3654], 'first': [3662], 'attacks': [3663], '30,': [3672], '675–679.': [3673], 'Flachs,': [3690], '5-Amino': [3693], 'slow': [3698], 'preparation:': [3700], 'bioavailability,': [3701], 'plasma': [3702], 'level': [3703], 'excretion': [3705, 3932, 3978], 'humans.': [3707], '1062–1070.': [3710], 'McLaughlin,': [3714], 'Brown,': [3717], 'Nuttall,': [3721], 'leucocyte': [3731], 'motility': [3732], 'prevention': [3734], 'immune': [3736], 'complex': [3737], 'hydrozychloroquine.': [3741], '23,': [3743, 4760], '181–187.': [3744], 'Riley,': [3745, 3786], 'Mani,': [3748, 3789], 'Goodman,': [3750, 3791], 'Herd,': [3753, 3794], 'Dutt,': [3756, 3797], 'Turnberg,': [3759, 3800], 'delayed': [3765, 3806], 'aminosalicylic': [3768, 3809], '(mesalazine)': [3770, 3811], 'mild': [3777], 'moderate': [3779], 'relapse.': [3782], '669–674.': [3785], '1383–1389.': [3824], 'High-dose': [3836], 'methylprednisolone': [3837], '12,': [3848], '40–41.': [3849], 'Wall,': [3853], 'Levin,': [3856], '69,': [3879, 4111], '96–99.': [3880], 'Rutgeerts,': [3881], 'Mesalazine': [3884], 'International': [3896], 'Congress': [3897], 'Rome,': [3900], 'abstract': [3901], '1666.': [3902], 'Sandberg-Gertzen,': [3903, 3922], 'Jarnerot,': [3905, 3927], 'Draaz,': [3908], 'Azodisal': [3911], '1024–1030.': [3921], 'Absorption': [3930], 'single': [3935], 'g': [3937], 'azodisal': [3940], 'ileostomy.': [3945], '107–111.': [3950], 'Schreiber,': [3951], 'Chemistry': [3955], 'biology': [3957], 'immunophilins': [3960], 'ligands.': [3964], 'Science,': [3965], '251,': [3966], '283–287.': [3967], 'Schroder,': [3968], 'Campbell,': [3971], 'Absorption,': [3975], '539–551.': [3987], 'Schwartz,': [3988], 'Preformed': [3992], 'mediators': [3993, 4003], 'basophils.': [3999], 'In': [4000], 'Mast': [4001], 'cells,': [4002], 'disease,': [4005], 'Holgate': [4008], 'pp.': [4009], '129–147.': [4010], 'Dordrecht:': [4011], 'Kluwer.': [4012], 'Barr,': [4016], '291,': [4037], '1373–1375.': [4038], 'Bennett,': [4042], '231–234.': [4061], 'Spencer,': [4062], 'Rectal': [4073], '6-α-(C-14)': [4076], 'methylprednisolone.': [4077], 'Proc.': [4078, 4256], 'Soc.': [4079, 4258], 'Biol.': [4081], 'Med,': [4082], '74–77': [4084], 'Lobos,': [4096], 'inhibits': [4100, 4198], 'synthesis': [4102], 'chemotactic': [4104], 'lipids': [4105], '494–497.': [4112], 'Cort,': [4116, 4156], 'DeSchryver-Kecskemeti,': [4118], 'Rodgers,': [4120], 'Burakoff,': [4122], 'Beeken,': [4125], '(1991b).': [4127], 'fish': [4131], 'supplemented': [4133], 'diet': [4134], 'A253.': [4141, 4187], 'Jacobsen,': [4152], 'Goebell,': [4158], 'Peskar,': [4160], 'Swanson,': [4164], 'Dube,': [4166], '(1991a).': [4171], 'zileuton,': [4176], 'specific': [4178], 'Mehta,': [4191], 'Spilberg,': [4194], 'formylmethionylleucylphenylalanine': [4202], '(FLMP)': [4203], 'Biochem.': [4210], '407–412.': [4213], 'Svartz,': [4214], 'Sulfasalazine': [4217], 'Some': [4219], 'notes': [4220], 'discovery': [4223], 'development': [4225], 'salazopyrin.': [4227], '497–503.': [4232], 'Loose,': [4236], 'Enema': [4243], 'volume': [4244], 'important': [4247], 'Roy.': [4257], '67,': [4260], '753–754.': [4261], 'Taffet,': [4262], 'Sulphasalazine;': [4270], 'adverse': [4271], 'densensitization.': [4274], '833–842.': [4279], 'Schlichting,': [4282], 'Thomson,': [4284, 4306], 'Hoybye,': [4287], 'Malignancies': [4294], 'following': [4295], 'long-term': [4296], 'liver': [4301], 'Liver,': [4303], '7,': [4304], '81–83.': [4305], 'developments': [4312], 'use': [4315], '449–470.': [4329], '(1958).': [4333], 'local': [4339, 4361], 'sodium.': [4342], '1072–1077.': [4354], 'Systemic': [4359], '464–467.': [4371], 'Watkinson,': [4375], 'Draper,': [4378], '(1962).': [4380], '1708–1711.': [4394], 'Witts,': [4399, 4422, 4445], '(1954).': [4402], 'Cortisone': [4403, 4426, 4449], '375–378.': [4417], '(1955).': [4425], 'Final': [4430], '1041–1048.': [4440], '(1959).': [4448], 'corticotrophin': [4451], '387–394.': [4459], 'Ursing,': [4460], 'Alm,': [4462], 'Barany,': [4464], 'Bergelin,': [4466], 'Ganrot-Norlin,': [4468], 'Hoevels,': [4470], 'Huitfeldt,': [4472], 'Jameröt,': [4474], 'Krause,': [4476], 'Krook,': [4478], 'Lindström,': [4480], 'Nordle,': [4482], 'Rosén,': [4485], 'cooperative': [4489, 4500], 'Sweden.': [4505], 'II': [4506], 'Result.': [4507], '550–562.': [4510], 'van': [4511, 4520, 4551, 4555, 4561], 'Hees,': [4512], 'Bakker,': [4516], 'Tongeren,': [4521], 'sulphapyridine,': [4528], 'proctitis:': [4537], '632–635.': [4550], 'Hogezand,': [4552], 'Hess,': [4556], 'Gorp,': [4562], 'acetyl': [4574], 'suppositories': [4577], 'proctitis.': [4582], '33–40.': [4587], 'von': [4588, 4601], 'Muhlendahl,': [4589], 'Nephritis': [4593], 'durch': [4594], '5-Aminosalicylsaure.': [4595], 'Deutsch': [4596], 'Wochenschr.,': [4598], '114,': [4599], '236.': [4600], 'Ritter,': [4602], 'Grisham,': [4604], 'Granger,': [4608], 'dapsone': [4615], 'attenuate': [4616], 'formylmethionyl-leucyl-phenylalanine': [4617], 'injury': [4620], 'ileum.': [4623], '811–816.': [4626], 'Wallace,': [4627], 'Steel,': [4630], 'Whittle,': [4632], 'Lagente,': [4636], 'Vergaftia,': [4639], 'platelet': [4644, 4660], 'activating': [4645, 4661], 'mediator': [4649], 'endotoxin-induced': [4651], 'gastrointestinal': [4652], 'antagonists.': [4663], '93,': [4665], '765–773.': [4666], 'Werlin,': [4667], 'Grand,': [4671], 'Severe': [4675], 'children': [4678], 'adolescents:': [4680], 'Diagnosis,': [4681], 'cause': [4682], 'treatment.': [4684], '73,': [4686], '828–832.': [4687], 'Willoughby,': [4688, 4712, 4727, 4762, 4796], '(1980a).': [4697], 'N-acetyl-5-aminosalicylic': [4702], '15,': [4710], '715–719.': [4711], '(1980b).': [4719], 'Ulcerative': [4720], 'pregnancy.': [4723], '469–474.': [4726], 'Aronson,': [4730], 'Agback,': [4733], 'Bodin,': [4735], 'azodisalicylate,': [4751], 'potential': [4753], '1081–1087.': [4761], 'Ital.': [4791], '15–17.': [4795], 'Cowan,': [4799], 'Machell,': [4805], 'Stewart,': [4809], '40–44.': [4830], 'Citing': [4831], 'Literature': [4832], 'Volume34,': [4833], 'Issue3September': [4834], '1992Pages': [4835], 'ReferencesRelatedInformation': [4837]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2080927482', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-09T08:22:22.725160', 'created_date': '2016-06-24'}