Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2080748037', 'doi': 'https://doi.org/10.1016/j.cell.2013.11.012', 'title': 'Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade', 'display_name': 'Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade', 'publication_year': 2013, 'publication_date': '2013-12-01', 'ids': {'openalex': 'https://openalex.org/W2080748037', 'doi': 'https://doi.org/10.1016/j.cell.2013.11.012', 'mag': '2080748037', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24315100', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3932525'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2013.11.012', 'pdf_url': 'https://www.cell.com/article/S0092867413014256/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.cell.com/article/S0092867413014256/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5071620573', 'display_name': 'Vivek Arora', 'orcid': 'https://orcid.org/0000-0003-1694-9109'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vivek\xa0K. Arora', 'raw_affiliation_strings': ['Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}, {'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091585330', 'display_name': 'Emily Schenkein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Emily Schenkein', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055849515', 'display_name': 'Rajmohan Murali', 'orcid': 'https://orcid.org/0000-0001-6988-4295'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rajmohan Murali', 'raw_affiliation_strings': ['Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}, {'raw_affiliation_string': 'Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021224140', 'display_name': 'Sumit K. Subudhi', 'orcid': 'https://orcid.org/0000-0001-5208-7732'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sumit\xa0K. Subudhi', 'raw_affiliation_strings': ['Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050228096', 'display_name': 'John Wongvipat', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John Wongvipat', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084198302', 'display_name': 'Minna Balbas', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Minna\xa0D. Balbas', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}, {'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109529034', 'display_name': 'Neel Shah', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Neel Shah', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}, {'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027842285', 'display_name': 'Ling Cai', 'orcid': 'https://orcid.org/0000-0002-8592-5269'}, 'institutions': [{'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ling Cai', 'raw_affiliation_strings': ['Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078910130', 'display_name': 'Eleni Efstathiou', 'orcid': 'https://orcid.org/0000-0002-3868-1396'}, 'institutions': [{'id': 'https://openalex.org/I1343551460', 'display_name': 'The University of Texas MD Anderson Cancer Center', 'ror': 'https://ror.org/04twxam07', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1343551460']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eleni Efstathiou', 'raw_affiliation_strings': ['Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA', 'institution_ids': ['https://openalex.org/I1343551460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112513277', 'display_name': 'Chris Logothetis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1343551460', 'display_name': 'The University of Texas MD Anderson Cancer Center', 'ror': 'https://ror.org/04twxam07', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1343551460']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chris Logothetis', 'raw_affiliation_strings': ['Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA', 'institution_ids': ['https://openalex.org/I1343551460']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053246999', 'display_name': 'Deyou Zheng', 'orcid': 'https://orcid.org/0000-0003-4354-5337'}, 'institutions': [{'id': 'https://openalex.org/I129975664', 'display_name': 'Albert Einstein College of Medicine', 'ror': 'https://ror.org/05cf8a891', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I129975664', 'https://openalex.org/I4210112371']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Deyou Zheng', 'raw_affiliation_strings': ['Departments of Neurology, Genetics, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA'], 'affiliations': [{'raw_affiliation_string': 'Departments of Neurology, Genetics, and Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA', 'institution_ids': ['https://openalex.org/I129975664']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5034963668', 'display_name': 'Charles L. Sawyers', 'orcid': 'https://orcid.org/0000-0003-4955-6475'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I1334819555', 'display_name': 'Memorial Sloan Kettering Cancer Center', 'ror': 'https://ror.org/02yrq0923', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1334819555']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Charles\xa0L. Sawyers', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA', 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA', 'institution_ids': ['https://openalex.org/I1344073410']}, {'raw_affiliation_string': 'Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I1334819555']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5034963668'], 'corresponding_institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I1334819555'], 'apc_list': {'value': 10100, 'currency': 'USD', 'value_usd': 10100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 57.848, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 909, 'citation_normalized_percentile': {'value': 0.999971, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '155', 'issue': '6', 'first_page': '1309', 'last_page': '1322'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10756', 'display_name': 'Estrogen and related hormone effects', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9861, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/enzalutamide', 'display_name': 'Enzalutamide', 'score': 0.94394207}, {'id': 'https://openalex.org/keywords/antiandrogens', 'display_name': 'Antiandrogens', 'score': 0.5699202}], 'concepts': [{'id': 'https://openalex.org/C2776551883', 'wikidata': 'https://www.wikidata.org/wiki/Q1996756', 'display_name': 'Enzalutamide', 'level': 5, 'score': 0.94394207}, {'id': 'https://openalex.org/C61367390', 'wikidata': 'https://www.wikidata.org/wiki/Q416601', 'display_name': 'Androgen receptor', 'level': 4, 'score': 0.8590224}, {'id': 'https://openalex.org/C59493245', 'wikidata': 'https://www.wikidata.org/wiki/Q14877410', 'display_name': 'Glucocorticoid receptor', 'level': 3, 'score': 0.79507464}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.75197965}, {'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.6776813}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.6100858}, {'id': 'https://openalex.org/C2777911890', 'wikidata': 'https://www.wikidata.org/wiki/Q62614', 'display_name': 'Androgen', 'level': 3, 'score': 0.6058218}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.5912591}, {'id': 'https://openalex.org/C2778468042', 'wikidata': 'https://www.wikidata.org/wiki/Q273976', 'display_name': 'Blockade', 'level': 3, 'score': 0.5730959}, {'id': 'https://openalex.org/C2910016293', 'wikidata': 'https://www.wikidata.org/wiki/Q574820', 'display_name': 'Antiandrogens', 'level': 5, 'score': 0.5699202}, {'id': 'https://openalex.org/C2780841215', 'wikidata': 'https://www.wikidata.org/wiki/Q422549', 'display_name': 'Glucocorticoid', 'level': 2, 'score': 0.54462993}, {'id': 'https://openalex.org/C63932345', 'wikidata': 'https://www.wikidata.org/wiki/Q422500', 'display_name': 'Nuclear receptor', 'level': 4, 'score': 0.51485294}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.48475596}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.4815269}, {'id': 'https://openalex.org/C2780401358', 'wikidata': 'https://www.wikidata.org/wiki/Q422252', 'display_name': 'Dexamethasone', 'level': 2, 'score': 0.4726041}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.46266866}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42537445}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.42285442}, {'id': 'https://openalex.org/C186310378', 'wikidata': 'https://www.wikidata.org/wiki/Q941796', 'display_name': 'Psychological repression', 'level': 4, 'score': 0.41743428}, {'id': 'https://openalex.org/C189135053', 'wikidata': 'https://www.wikidata.org/wiki/Q3454531', 'display_name': 'Mineralocorticoid receptor', 'level': 3, 'score': 0.416945}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.25640973}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.25040048}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.14999089}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.13620684}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1352914}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.10434586}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.08026332}, {'id': 'https://openalex.org/C2778525890', 'wikidata': 'https://www.wikidata.org/wiki/Q184564', 'display_name': 'Aldosterone', 'level': 2, 'score': 0.07401639}], 'mesh': [{'descriptor_ui': 'D000726', 'descriptor_name': 'Androgen Antagonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D059002', 'descriptor_name': 'Androgen Receptor Antagonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D011965', 'descriptor_name': 'Receptors, Glucocorticoid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000726', 'descriptor_name': 'Androgen Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059002', 'descriptor_name': 'Androgen Receptor Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001549', 'descriptor_name': 'Benzamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064593', 'descriptor_name': 'Heterografts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009368', 'descriptor_name': 'Neoplasm Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009570', 'descriptor_name': 'Nitriles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010669', 'descriptor_name': 'Phenylthiohydantoin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011944', 'descriptor_name': 'Receptors, Androgen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011944', 'descriptor_name': 'Receptors, Androgen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011965', 'descriptor_name': 'Receptors, Glucocorticoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059467', 'descriptor_name': 'Transcriptome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2013.11.012', 'pdf_url': 'https://www.cell.com/article/S0092867413014256/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3932525', 'pdf_url': 'https://europepmc.org/articles/pmc3932525?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932525', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24315100', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2013.11.012', 'pdf_url': 'https://www.cell.com/article/S0092867413014256/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W1797512951', 'https://openalex.org/W1970916644', 'https://openalex.org/W1980497534', 'https://openalex.org/W1981082529', 'https://openalex.org/W1998971866', 'https://openalex.org/W1999025555', 'https://openalex.org/W2003955264', 'https://openalex.org/W2015015957', 'https://openalex.org/W2021271765', 'https://openalex.org/W2025919590', 'https://openalex.org/W2031943423', 'https://openalex.org/W2036006424', 'https://openalex.org/W2055624262', 'https://openalex.org/W2080134152', 'https://openalex.org/W2084637523', 'https://openalex.org/W2101606728', 'https://openalex.org/W2110534364', 'https://openalex.org/W2113327188', 'https://openalex.org/W2119504728', 'https://openalex.org/W2121846636', 'https://openalex.org/W2124985265', 'https://openalex.org/W2128542677', 'https://openalex.org/W2130189600', 'https://openalex.org/W2131967029', 'https://openalex.org/W2132157071', 'https://openalex.org/W2134988422', 'https://openalex.org/W2141674733', 'https://openalex.org/W2142969636', 'https://openalex.org/W2148643283', 'https://openalex.org/W2157009395', 'https://openalex.org/W2157980218', 'https://openalex.org/W2160975559', 'https://openalex.org/W2166095387', 'https://openalex.org/W2171808845', 'https://openalex.org/W2172256092'], 'related_works': ['https://openalex.org/W566057629', 'https://openalex.org/W4250573295', 'https://openalex.org/W3212968832', 'https://openalex.org/W2401260650', 'https://openalex.org/W2165563122', 'https://openalex.org/W2140683271', 'https://openalex.org/W2052533806', 'https://openalex.org/W2041734836', 'https://openalex.org/W2040882963', 'https://openalex.org/W2020185368'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2080748037', 'counts_by_year': [{'year': 2024, 'cited_by_count': 63}, {'year': 2023, 'cited_by_count': 91}, {'year': 2022, 'cited_by_count': 85}, {'year': 2021, 'cited_by_count': 95}, {'year': 2020, 'cited_by_count': 89}, {'year': 2019, 'cited_by_count': 77}, {'year': 2018, 'cited_by_count': 81}, {'year': 2017, 'cited_by_count': 79}, {'year': 2016, 'cited_by_count': 83}, {'year': 2015, 'cited_by_count': 77}, {'year': 2014, 'cited_by_count': 78}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-20T08:38:24.001785', 'created_date': '2016-06-24'}