Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2080714599', 'doi': 'https://doi.org/10.1016/j.yexmp.2015.03.015', 'title': 'Significance of FBX8 in progression of gastric cancer', 'display_name': 'Significance of FBX8 in progression of gastric cancer', 'publication_year': 2015, 'publication_date': '2015-06-01', 'ids': {'openalex': 'https://openalex.org/W2080714599', 'doi': 'https://doi.org/10.1016/j.yexmp.2015.03.015', 'mag': '2080714599', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25801334'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.yexmp.2015.03.015', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111757857', 'display_name': 'Experimental and Molecular Pathology', 'issn_l': '0014-4800', 'issn': ['0014-4800', '1096-0945'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076066485', 'display_name': 'Pingxiang Wu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Pingxiang Wu', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100442820', 'display_name': 'Feifei Wang', 'orcid': 'https://orcid.org/0000-0002-5962-3136'}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Feifei Wang', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100721619', 'display_name': 'Yi Wang', 'orcid': 'https://orcid.org/0000-0003-4028-2471'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yi Wang', 'raw_affiliation_strings': ["Department of Pathophysiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Pathophysiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072951808', 'display_name': 'Hui Men', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hui Men', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072952011', 'display_name': 'Xiaohui Zhu', 'orcid': 'https://orcid.org/0000-0001-9146-8909'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaohui Zhu', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}, {'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039809760', 'display_name': 'Guoyang He', 'orcid': 'https://orcid.org/0000-0001-6824-4085'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guoyang He', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}, {'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101524030', 'display_name': 'Wenhui Ma', 'orcid': 'https://orcid.org/0000-0002-8600-1594'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenhui Ma', 'raw_affiliation_strings': ["Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027101510', 'display_name': 'Sainan Xin', 'orcid': 'https://orcid.org/0009-0008-1491-5339'}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Sainan Xin', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101639401', 'display_name': 'Jianhua Wu', 'orcid': 'https://orcid.org/0000-0003-4142-8903'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianhua Wu', 'raw_affiliation_strings': ["First School of Clinical Medicine, Southern Medical University, Guangzhou city 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "First School of Clinical Medicine, Southern Medical University, Guangzhou city 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102963298', 'display_name': 'Wenting Liao', 'orcid': 'https://orcid.org/0000-0003-4953-3134'}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenting Liao', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}, {'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001756427', 'display_name': 'Yanqing Ding', 'orcid': 'https://orcid.org/0000-0003-1775-6923'}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yanqing Ding', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100528017', 'display_name': 'Mei-Rong He', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}, {'id': 'https://openalex.org/I4210103346', 'display_name': 'Nanfang Hospital', 'ror': 'https://ror.org/01eq10738', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103346']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Meirong He', 'raw_affiliation_strings': ["Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China."], 'affiliations': [{'raw_affiliation_string': "Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China.", 'institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100420716', 'display_name': 'Liang Li', 'orcid': 'https://orcid.org/0000-0003-1893-1965'}, 'institutions': [{'id': 'https://openalex.org/I4210098034', 'display_name': 'Key Laboratory of Guangdong Province', 'ror': 'https://ror.org/00swtqp09', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210098034']}, {'id': 'https://openalex.org/I58200834', 'display_name': 'Southern Medical University', 'ror': 'https://ror.org/01vjw4z39', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I58200834']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Li Liang', 'raw_affiliation_strings': ["Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Guangdong Province Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, Guangdong province, People's Republic of China", 'institution_ids': ['https://openalex.org/I4210098034']}, {'raw_affiliation_string': "Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou City 510515, Guangdong Province, People's Republic of China", 'institution_ids': ['https://openalex.org/I58200834']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5100528017', 'https://openalex.org/A5100420716'], 'corresponding_institution_ids': ['https://openalex.org/I58200834', 'https://openalex.org/I4210103346', 'https://openalex.org/I4210098034', 'https://openalex.org/I58200834'], 'apc_list': {'value': 1900, 'currency': 'USD', 'value_usd': 1900, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.393, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 15, 'citation_normalized_percentile': {'value': 0.865308, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '98', 'issue': '3', 'first_page': '360', 'last_page': '366'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10620', 'display_name': 'Role of Matrix Metalloproteinases in Cancer and Physiology', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12505', 'display_name': 'Role of Fibroblast Activation in Cancer Progression', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-progression', 'display_name': 'Cancer Progression', 'score': 0.52286}, {'id': 'https://openalex.org/keywords/clinical-significance', 'display_name': 'Clinical significance', 'score': 0.49198934}], 'concepts': [{'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.77529824}, {'id': 'https://openalex.org/C204232928', 'wikidata': 'https://www.wikidata.org/wiki/Q899285', 'display_name': 'Immunohistochemistry', 'level': 2, 'score': 0.77358735}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.7509254}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.59502864}, {'id': 'https://openalex.org/C85265743', 'wikidata': 'https://www.wikidata.org/wiki/Q885458', 'display_name': 'Blot', 'level': 3, 'score': 0.5777317}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.53134805}, {'id': 'https://openalex.org/C63363279', 'wikidata': 'https://www.wikidata.org/wiki/Q5133848', 'display_name': 'Clinical significance', 'level': 2, 'score': 0.49198934}, {'id': 'https://openalex.org/C96232424', 'wikidata': 'https://www.wikidata.org/wiki/Q4118072', 'display_name': 'Cancer cell', 'level': 3, 'score': 0.48615167}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.46194655}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.41867626}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.4163616}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.4152082}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.34161597}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.24754786}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.074073195}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016513', 'descriptor_name': 'Mice, SCID', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009362', 'descriptor_name': 'Neoplasm Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.yexmp.2015.03.015', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111757857', 'display_name': 'Experimental and Molecular Pathology', 'issn_l': '0014-4800', 'issn': ['0014-4800', '1096-0945'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25801334', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.52, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81272759'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81172382'}, {'funder': 'https://openalex.org/F4320321001', 'funder_display_name': 'National Natural Science Foundation of China', 'award_id': '81472313'}, {'funder': 'https://openalex.org/F4320335777', 'funder_display_name': 'National Key Research and Development Program of China', 'award_id': '2015CB554002'}], 'datasets': [], 'versions': [], 'referenced_works_count': 25, 'referenced_works': ['https://openalex.org/W1852163795', 'https://openalex.org/W1990332659', 'https://openalex.org/W1991097958', 'https://openalex.org/W1997173534', 'https://openalex.org/W2015866661', 'https://openalex.org/W2021115672', 'https://openalex.org/W2025519885', 'https://openalex.org/W2047238468', 'https://openalex.org/W2054571220', 'https://openalex.org/W2073856026', 'https://openalex.org/W2075612860', 'https://openalex.org/W2079929902', 'https://openalex.org/W2083640838', 'https://openalex.org/W2083651422', 'https://openalex.org/W2089389511', 'https://openalex.org/W2093075930', 'https://openalex.org/W2106787323', 'https://openalex.org/W2112357436', 'https://openalex.org/W2132653353', 'https://openalex.org/W2142183096', 'https://openalex.org/W2144993348', 'https://openalex.org/W2155048968', 'https://openalex.org/W2168803087', 'https://openalex.org/W2171932084', 'https://openalex.org/W2180001315'], 'related_works': ['https://openalex.org/W4361006991', 'https://openalex.org/W4213439341', 'https://openalex.org/W4200146410', 'https://openalex.org/W3006214768', 'https://openalex.org/W2611246058', 'https://openalex.org/W2343201566', 'https://openalex.org/W2131943779', 'https://openalex.org/W20149564', 'https://openalex.org/W1999169586', 'https://openalex.org/W1989330519'], 'abstract_inverted_index': {'F-box': [0, 9], 'only': [1], 'protein': [2], '8': [3], '(FBX8),': [4], 'a': [5, 197], 'novel': [6], 'component': [7], 'of': [8, 25, 33, 41, 58, 67, 87, 92, 99, 108, 157, 179, 203], 'proteins,': [10], 'has': [11], 'recently': [12], 'been': [13], 'observed': [14], 'in': [15, 22, 43, 60, 89, 114, 118, 124, 152, 159, 175, 190], 'several': [16], 'malignancies.': [17], 'However,': [18], 'its': [19, 49], 'clinical': [20, 93], 'implication': [21], 'the': [23, 39, 106, 165], 'progression': [24, 53], 'gastric': [26, 44, 69], 'cancer': [27, 45, 70], 'still': [28], 'remains': [29], 'unclear.': [30], 'The': [31, 56], 'aim': [32], 'this': [34], 'study': [35], 'was': [36, 81, 121, 170], 'to': [37, 83, 104, 128, 172], 'explore': [38], 'role': [40], 'FBX8': [42, 59, 88, 109, 120, 135, 146, 158, 169, 180, 193], '(GC)': [46], 'and': [47, 54, 64, 77, 112, 116, 141, 150, 161, 186], 'analyze': [48, 84], 'correlation': [50], 'with': [51, 133, 183], 'tumor': [52], 'prognosis.': [55, 143], 'expression': [57], 'GC': [61, 95, 125, 191, 204], 'cell': [62], 'lines': [63], 'matched': [65], 'pairs': [66], 'fresh': [68], 'tissues': [71, 126], 'were': [72, 102], 'detected': [73], 'by': [74], 'real-time': [75], 'RT-PCR': [76], 'Western': [78], 'blotting.': [79], 'Immunohistochemistry': [80], 'used': [82], 'clinicopathological': [85], 'patterns': [86], '136': [90], 'cases': [91], 'paraffin-embedded': [94], 'tissues.': [96, 131], 'A': [97], 'series': [98], 'functional': [100], 'assays': [101], 'conducted': [103], 'evaluate': [105], 'effect': [107], 'on': [110], 'proliferation': [111, 149], 'invasion': [113, 151], 'vitro': [115], 'metastasis': [117, 174, 185], 'vivo.': [119], 'markedly': [122], 'down-regulated': [123], 'compared': [127], 'adjacent': [129], 'normal': [130], 'Patients': [132], 'low': [134], 'had': [136, 164], 'shorter': [137], 'overall': [138], 'survival': [139, 188], 'time': [140, 189], 'poor': [142, 187], 'Knocking': [144], 'down': [145], 'obviously': [147], 'promoted': [148], 'BGC823': [153], 'cells,': [154], 'while': [155], 'over-expression': [156], 'SGC7901': [160], 'AGS': [162], 'cells': [163], 'opposite': [166], 'effects.': [167], 'Moreover,': [168], 'sufficient': [171], 'suppress': [173], 'nude': [176], 'mice.': [177], 'Down-regulation': [178], 'significantly': [181], 'correlates': [182], 'invasion,': [184], 'patients.': [192], 'may': [194], 'serve': [195], 'as': [196], 'promising': [198], 'therapeutic': [199], 'target': [200], 'for': [201], 'inhibition': [202], 'metastasis.': [205]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2080714599', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-09-10T11:04:35.585230', 'created_date': '2016-06-24'}