A new approach to porphobilinogen and its analogs

Name: Work Video:
Duration: 3 min 30 s
Description: The van Leusen pyrrole synthesis was used to assemble three potential precursors of porphobilinogen, one of which was converted to the natural product using a new method for the direct alkylation of β-hydroxymethylpyrroles.
C. Y. DE LEON; Bruce Ganem
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