Effect of plasmapheresis on serum and CSF autoantibody levels in CNS paraneoplastic syndromes

Name: Work Video:
Duration: 3 min 30 s
Description: We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.
Francesc Graus; J Abós; Jaume Roquer; Roberto Mazzara; Ana Paula de Pereira
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Graus', 'raw_affiliation_strings': ["From the Departments of Neurology, and Hemotherapy and Hemostasis, Hospital Clinic i Provincial, and Department of Neurology, Hospital del' Esperanca, Barcelona, Spain."], 'affiliations': [{'raw_affiliation_string': "From the Departments of Neurology, and Hemotherapy and Hemostasis, Hospital Clinic i Provincial, and Department of Neurology, Hospital del' Esperanca, Barcelona, Spain.", 'institution_ids': ['https://openalex.org/I4210111971']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033342674', 'display_name': 'J Abós', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210111971', 'display_name': "Hospital de l'Esperança", 'ror': 'https://ror.org/023733d09', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111971']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'J. 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