Title: Pharmacological Studies on the Effect of the Treatment of Swiss A Mice with Diospyrin, a Tumour-inhibitory Plant Product, and its Synthetic Derivatives
Abstract: Phytotherapy ResearchVolume 10, Issue 5 p. 393-397 Research Article Pharmacological Studies on the Effect of the Treatment of Swiss A Mice with Diospyrin, a Tumour-inhibitory Plant Product, and its Synthetic Derivatives Sampa Pal, Sampa Pal Departments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorAmalendu Banerjee, Amalendu Banerjee Departments of Chemistry, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorBanasri Hazra, Corresponding Author Banasri Hazra Departments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaDepartments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorRatnamala Ray, Ratnamala Ray Ashok Laboratory and Clinical Research Centre, 390B, Jodhpur Park, Calcutta 700 068, IndiaSearch for more papers by this authorDilip K. Bhattacharya, Dilip K. Bhattacharya Ashok Laboratory and Clinical Research Centre, 390B, Jodhpur Park, Calcutta 700 068, IndiaSearch for more papers by this author Sampa Pal, Sampa Pal Departments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorAmalendu Banerjee, Amalendu Banerjee Departments of Chemistry, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorBanasri Hazra, Corresponding Author Banasri Hazra Departments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaDepartments of Pharmacy, Jadavpur University, Calcutta 700 032, IndiaSearch for more papers by this authorRatnamala Ray, Ratnamala Ray Ashok Laboratory and Clinical Research Centre, 390B, Jodhpur Park, Calcutta 700 068, IndiaSearch for more papers by this authorDilip K. Bhattacharya, Dilip K. Bhattacharya Ashok Laboratory and Clinical Research Centre, 390B, Jodhpur Park, Calcutta 700 068, IndiaSearch for more papers by this author First published: August 1996 https://doi.org/10.1002/(SICI)1099-1573(199608)10:5<393::AID-PTR859>3.0.CO;2-XCitations: 9AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Diospyrin, a bisnaphthoquinonoid plant product and its derivatives have shown significant inhibitory activities against murine tumours in vivo. Studies on the haematological status, serum protein and creatinine levels, activities of several serum glycolytic enzymes, and histopathology of the mice inoculated with Ehrlich ascites carcinoma were carried out after treatment with diospyrin and four synthetic derivatives. The prognostic significance of the pharmacological parameters acting as markers of the diseased state was evident from these findings. Normal mice were also studied before and after treatment with these compounds which did not cause noticeable adverse effects on the vital parameters, thereby indicating the possibility of the utilization of diospyrin and derivatives as appropriate therapeutic agents. References Anon. (1952). The Wealth of India:Raw Materials, Vol III, p. 84. Council of Scientific and Industrial Research, New Delhi. Google Scholar Bacci, G., Picci, P., Ferrari, S. et al. (1993). 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Publication Year: 1996
Publication Date: 1996-08-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 15
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