Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2078342972', 'doi': 'https://doi.org/10.1002/etc.5620161220', 'title': 'Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (<i>Salmo salar</i>) liver treated with an estrogenic compound, 4‐nonylphenol', 'display_name': 'Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (<i>Salmo salar</i>) liver treated with an estrogenic compound, 4‐nonylphenol', 'publication_year': 1997, 'publication_date': '1997-12-01', 'ids': {'openalex': 'https://openalex.org/W2078342972', 'doi': 'https://doi.org/10.1002/etc.5620161220', 'mag': '2078342972'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/etc.5620161220', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136710263', 'display_name': 'Environmental Toxicology and Chemistry', 'issn_l': '0730-7268', 'issn': ['0730-7268', '1552-8618'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085320289', 'display_name': 'Augustine Arukwe', 'orcid': 'https://orcid.org/0000-0002-2134-4799'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Augustine Arukwe', 'raw_affiliation_strings': ['Department of Molecular Biology, University of Bergen, HIB, N-5020 Bergen, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biology, University of Bergen, HIB, N-5020 Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084320009', 'display_name': 'Lárs Förlin', 'orcid': 'https://orcid.org/0000-0002-1923-7097'}, 'institutions': [{'id': 'https://openalex.org/I881427289', 'display_name': 'University of Gothenburg', 'ror': 'https://ror.org/01tm6cn81', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I881427289']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Lars Förlin', 'raw_affiliation_strings': ['Department of Zoophysiology, University of Göteborg, Medicinaregatan 18, S‐41390 Göteborg, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Zoophysiology, University of Göteborg, Medicinaregatan 18, S‐41390 Göteborg, Sweden', 'institution_ids': ['https://openalex.org/I881427289']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047098902', 'display_name': 'Anders Goksøyr', 'orcid': 'https://orcid.org/0000-0003-4054-9842'}, 'institutions': [{'id': 'https://openalex.org/I4432739', 'display_name': 'University of Bergen', 'ror': 'https://ror.org/03zga2b32', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I4432739']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Anders Goksøyr', 'raw_affiliation_strings': ['Department of Molecular Biology, University of Bergen, HIB, N-5020 Bergen, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biology, University of Bergen, HIB, N-5020 Bergen, Norway', 'institution_ids': ['https://openalex.org/I4432739']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3400, 'currency': 'USD', 'value_usd': 3400, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.906, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 185, 'citation_normalized_percentile': {'value': 0.943563, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '16', 'issue': '12', 'first_page': '2576', 'last_page': '2583'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11505', 'display_name': 'Reproductive biology and impacts on aquatic species', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11505', 'display_name': 'Reproductive biology and impacts on aquatic species', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10450', 'display_name': 'Aquaculture Nutrition and Growth', 'score': 0.987, 'subfield': {'id': 'https://openalex.org/subfields/1104', 'display_name': 'Aquatic Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10419', 'display_name': 'Pharmaceutical and Antibiotic Environmental Impacts', 'score': 0.9721, 'subfield': {'id': 'https://openalex.org/subfields/2310', 'display_name': 'Pollution'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/xenobiotic', 'display_name': 'Xenobiotic', 'score': 0.8612717}, {'id': 'https://openalex.org/keywords/cyp3a', 'display_name': 'CYP3A', 'score': 0.70613027}, {'id': 'https://openalex.org/keywords/biotransformation', 'display_name': 'Biotransformation', 'score': 0.66418624}, {'id': 'https://openalex.org/keywords/nonylphenol', 'display_name': 'Nonylphenol', 'score': 0.51788545}, {'id': 'https://openalex.org/keywords/microsoma', 'display_name': 'Microsoma', 'score': 0.41494146}], 'concepts': [{'id': 'https://openalex.org/C2777940460', 'wikidata': 'https://www.wikidata.org/wiki/Q310436', 'display_name': 'Salmo', 'level': 3, 'score': 0.87506187}, {'id': 'https://openalex.org/C115448650', 'wikidata': 'https://www.wikidata.org/wiki/Q409205', 'display_name': 'Xenobiotic', 'level': 3, 'score': 0.8612717}, {'id': 'https://openalex.org/C11824378', 'wikidata': 'https://www.wikidata.org/wiki/Q5014970', 'display_name': 'CYP3A', 'level': 4, 'score': 0.70613027}, {'id': 'https://openalex.org/C526171541', 'wikidata': 'https://www.wikidata.org/wiki/Q407693', 'display_name': 'Cytochrome P450', 'level': 3, 'score': 0.6679807}, {'id': 'https://openalex.org/C27881333', 'wikidata': 'https://www.wikidata.org/wiki/Q864895', 'display_name': 'Biotransformation', 'level': 3, 'score': 0.66418624}, {'id': 'https://openalex.org/C87644729', 'wikidata': 'https://www.wikidata.org/wiki/Q547502', 'display_name': 'Microsome', 'level': 3, 'score': 0.6231776}, {'id': 'https://openalex.org/C2780902042', 'wikidata': 'https://www.wikidata.org/wiki/Q177911', 'display_name': 'Steroid', 'level': 3, 'score': 0.5888568}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.5375905}, {'id': 'https://openalex.org/C2780155452', 'wikidata': 'https://www.wikidata.org/wiki/Q416769', 'display_name': 'Nonylphenol', 'level': 2, 'score': 0.51788545}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5097551}, {'id': 'https://openalex.org/C119795356', 'wikidata': 'https://www.wikidata.org/wiki/Q407801', 'display_name': 'Isozyme', 'level': 3, 'score': 0.50942665}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5076479}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.49228492}, {'id': 'https://openalex.org/C115961737', 'wikidata': 'https://www.wikidata.org/wiki/Q1516282', 'display_name': 'Juvenile', 'level': 2, 'score': 0.47003716}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.45216337}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.43945813}, {'id': 'https://openalex.org/C2777164284', 'wikidata': 'https://www.wikidata.org/wiki/Q277954', 'display_name': 'Estrogen', 'level': 2, 'score': 0.4182692}, {'id': 'https://openalex.org/C2776524530', 'wikidata': 'https://www.wikidata.org/wiki/Q4119721', 'display_name': 'Microsoma', 'level': 4, 'score': 0.41494146}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.36175683}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.23210666}, {'id': 'https://openalex.org/C2909208804', 'wikidata': 'https://www.wikidata.org/wiki/Q127282', 'display_name': 'Fish <Actinopterygii>', 'level': 2, 'score': 0.21148458}, {'id': 'https://openalex.org/C107872376', 'wikidata': 'https://www.wikidata.org/wiki/Q321355', 'display_name': 'Environmental chemistry', 'level': 1, 'score': 0.15912029}, {'id': 'https://openalex.org/C505870484', 'wikidata': 'https://www.wikidata.org/wiki/Q180538', 'display_name': 'Fishery', 'level': 1, 'score': 0.14308813}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.08136788}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/etc.5620161220', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136710263', 'display_name': 'Environmental Toxicology and Chemistry', 'issn_l': '0730-7268', 'issn': ['0730-7268', '1552-8618'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.89, 'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W146498581', 'https://openalex.org/W1604915447', 'https://openalex.org/W1867714524', 'https://openalex.org/W1929257083', 'https://openalex.org/W1963629346', 'https://openalex.org/W1967483279', 'https://openalex.org/W1970425626', 'https://openalex.org/W1974961743', 'https://openalex.org/W1984188309', 'https://openalex.org/W1986286660', 'https://openalex.org/W1988695122', 'https://openalex.org/W1991038461', 'https://openalex.org/W1991695793', 'https://openalex.org/W1996899952', 'https://openalex.org/W1997182869', 'https://openalex.org/W2002021255', 'https://openalex.org/W2007957335', 'https://openalex.org/W2017251086', 'https://openalex.org/W2018401640', 'https://openalex.org/W2020597160', 'https://openalex.org/W2027632176', 'https://openalex.org/W2036299239', 'https://openalex.org/W2039918315', 'https://openalex.org/W2043467102', 'https://openalex.org/W2047841570', 'https://openalex.org/W2050579373', 'https://openalex.org/W2053696401', 'https://openalex.org/W2054360588', 'https://openalex.org/W2054767188', 'https://openalex.org/W2061947638', 'https://openalex.org/W2066439231', 'https://openalex.org/W2067589028', 'https://openalex.org/W2070023191', 'https://openalex.org/W2076474201', 'https://openalex.org/W2086691916', 'https://openalex.org/W2089186774', 'https://openalex.org/W2090728306', 'https://openalex.org/W2100837269', 'https://openalex.org/W2101108802', 'https://openalex.org/W2128635872', 'https://openalex.org/W2412989477', 'https://openalex.org/W4229668875', 'https://openalex.org/W4293247451', 'https://openalex.org/W4313371825', 'https://openalex.org/W566368398'], 'related_works': ['https://openalex.org/W4389943749', 'https://openalex.org/W4386284808', 'https://openalex.org/W4253491312', 'https://openalex.org/W2974428425', 'https://openalex.org/W2460586648', 'https://openalex.org/W2401924522', 'https://openalex.org/W2125768955', 'https://openalex.org/W2076719315', 'https://openalex.org/W2037671877', 'https://openalex.org/W2013015354'], 'abstract_inverted_index': {'Abstract': [0], 'Hepatic': [1], 'microsomal': [2], 'biotransformation': [3], 'reactions': [4], 'with': [5, 46, 117, 125, 166], 'xenobiotic': [6], 'and': [7, 19, 35, 52, 61, 70, 97, 103, 146], 'steroid': [8, 141], 'substrates': [9], 'have': [10], 'been': [11], 'investigated': [12], 'in': [13, 31, 57, 64, 106, 113, 140, 150, 170], '4‐non‐ylphenol': [14], '(NP;': [15], '1,': [16], '5,': [17], '25,': [18], '125': [20, 118], 'mg/kg': [21], 'body': [22], 'weight)‐treated': [23], 'juvenile': [24, 44, 152], 'Atlantic': [25], 'salmon': [26, 45], '(': [27], 'Salmo': [28], 'salar': [29], '),': [30], 'addition': [32], 'to': [33], 'control': [34], 'estradiol‐17β': [36, 79], '(5': [37], 'mg/kg,': [38], 'positive': [39], 'control)‐treated': [40], 'fish.': [41, 121], 'Treatment': [42], 'of': [43, 78, 89, 94, 160], 'NP': [47, 90, 161], 'caused': [48], 'an': [49, 53, 167], 'initial': [50], 'increase': [51], 'apparent': [54], 'dose‐dependent': [55], 'decrease': [56], 'progesterone': [58], '6β‐,': [59], '16α,': [60], '17α‐hydroxylase': [62], 'activities': [63, 72], 'liver': [65], 'microsomes.': [66], '7‐Ethoxyresorufin': [67], 'O': [68], '‐deethylase': [69], 'UDP‐glucuronosyltransferase': [71], 'were': [73, 83], 'also': [74, 128], 'reduced.': [75], 'Plasma': [76], 'levels': [77, 149], '(E': [80], '2': [81, 127], ')': [82], 'lowered': [84], '24–43%': [85], 'as': [86], 'a': [87, 157], 'result': [88], 'treatment.': [91], 'Immunochemical': [92], 'analysis': [93], 'CYP1A,': [95], 'CYP2K‐like,': [96], 'CYP3A‐like': [98], 'proteins': [99], 'showed': [100, 129], '18%,': [101], '47%,': [102], '30%': [104], 'reductions': [105], 'enzyme‐linked': [107], 'immunosorbent': [108], 'assay': [109], 'absorbance': [110], 'levels,': [111], 'respectively,': [112], 'the': [114, 134], 'groups': [115], 'treated': [116, 124], 'mg': [119], 'NP/kg': [120], 'The': [122], 'group': [123], 'E': [126], 'similar': [130], 'reductions.': [131], 'In': [132], 'summary,': [133], 'present': [135], 'study': [136], 'has': [137], 'demonstrated': [138, 165], 'variations': [139], 'hydroxylases,': [142], 'cytochrome': [143], 'P450': [144], 'isozymes,': [145], 'conjugating': [147], 'enzyme': [148], 'NP‐treated': [151], 'salmon.': [153], 'These': [154], 'results': [155], 'represent': [156], 'novel': [158], 'aspect': [159], 'effects': [162], 'not': [163], 'previously': [164], 'environmental': [168], 'estrogen': [169], 'any': [171], 'fish': [172], 'species': [173], 'or': [174], 'lower': [175], 'vertebrate.': [176]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2078342972', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-11T16:30:59.718913', 'created_date': '2016-06-24'}