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1195, 1216, 1249, 1404, 1430, 1461, 1489, 1500, 1525, 1595, 1598, 1630, 1633], 'response': [280, 1215], 'injury,': [282], 'infection,': [283], 'or': [284, 1170], 'inflammation': [285, 446], 'central': [288], 'nervous': [289, 443, 1302, 1374], 'system': [290, 1214, 1303], '(CNS)': [291], 'mediate': [292], 'both': [293], 'neurotoxic': [294], 'neurotrophic': [296, 1171], 'activities.': [297], 'Although': [298], 'cytotoxic': [300], 'effects': [301, 328], 'microglia': [303, 406, 432, 942, 1021, 1398, 1597], 'been': [305], 'analyzed': [306], 'detail,': [308], 'little': [309], 'is': [310, 385, 559, 1018, 1046, 1657], 'known': [311, 378], 'about': [312], 'signaling': [314, 1138, 1298], 'pathways': [315, 1139], 'involved': [316, 386, 1629], 'neurotrophin': [319, 752], 'expression.': [320], 'Using': [321], 'purified': [322], 'rat': [323, 691, 719, 1190, 1250, 1350, 1413, 1599], 'cell': [325, 1154, 1285], 'cultures,': [326], 'inflammatory': [330, 388, 423, 589, 1246], 'agents': [331], 'such': [332], 'as': [333, 1402, 1453], 'lipopolysaccharide': [334, 1253, 1660], '(LPS)': [335], 'on': [336, 1563], '(NGF)': [341], 'were': [343], 'studied.': [344], 'Application': [345], 'LPS': [347], '(0.1–100': [348], 'ng/ml)': [349], 'induced': [350, 1248], 'rapid': [352], '(2–4': [353], 'h),': [354], 'dose-dependent': [355], 'increase': [356], 'NGF': [358, 366, 390, 410, 420, 428, 1194, 1631], 'mRNA': [359, 851], 'followed': [361], 'enhanced': [363], 'release': [364, 481, 891, 1193, 1344], 'protein': [367, 569, 853, 1299], 'within': [368], '24': [369], 'h.': [370], 'To': [371], 'determine': [372], 'whether': [373], 'transcription': [375, 585, 1279], 'NF-κB,': [377], 'be': [380], 'stimulated': [381], 'microglia,': [384], 'mediator-induced': [389], 'expression,': [391], 'we': [392], 'used': [393], 'inhibitor': [396], 'pyrrolidine': [397], 'dithiocarbamate': [398], '(PDTC).': [399], 'Addition': [400], 'PDTC': [402], '(100': [403], 'μM)': [404], 'completely': [407], 'abolished': [408], 'LPS-induced': [409], 'synthesis,': [411], 'suggesting': [412], 'key': [414], 'role': [415, 647], 'mediators.': [424], 'In': [425], 'conclusion,': [426], 'NF-κB-controlled': [427], 'appears': [433], 'contribute': [435], 'cross-talk': [438], 'between': [439, 1300, 1372], 'immune': [441, 1306, 1376], 'systems': [444], 'during': [445, 1022], 'CNS.': [449, 1110], 'GLIA': [450], '22:401–407,': [451], '1998.': [452], '©': [453], 'Wiley-Liss,': [455], 'Inc.': [456], 'References': [457], 'Araujo,': [458], 'D.': [459, 644, 938, 965, 1339, 1443], 'M.': [460, 492, 579, 613, 666, 707, 1162, 1320, 1534, 1552], 'Cotman,': [462], 'C.': [463, 643, 1041, 1226, 1651], 'W.': [464, 530, 550, 639, 705, 766, 1100, 1384, 1394, 1549, 1557], '(1992)': [465, 1451], 'Basic': [466], 'FGF': [467], 'astroglial,': [469], 'microglial,': [470], 'neuronal': [472, 1087, 1284], 'cultures:': [473], 'Characterization': [474], 'binding': [476], 'sites': [477], 'modulation': [479], 'lymphokines': [483], 'trophic': [485], 'factors': [486], 'J.': [487, 502, 576, 593, 694, 829, 841, 923, 951, 993, 1013, 1026, 1157, 1174, 1220, 1271, 1319, 1360, 1423, 1464, 1476, 1503, 1584, 1638, 1646, 1673], 'Neurosci.,': [488, 830, 924, 1112, 1288, 1504], '12:': [489, 1436], '1668–1678.': [490], 'Bader,': [491], 'F.,': [493, 640, 956], 'Taupenot,': [494], 'L.,': [495, 931, 1203, 1229, 1361], 'Ulrich,': [496], 'G.,': [497, 1334], 'Aunis,': [498], 'D.,': [499, 727, 763, 1235], 'Ciesielskitreska,': [501], '(1994)': [503, 768, 1014, 1166, 1369], 'Bacterial': [504], 'endotoxin': [505], 'induces': [506, 713], 'Ca2+': [507], 'transients': [508], 'changes': [510], 'organisation': [512], 'actin': [514], 'microglia.': [516, 534, 692, 775, 1263, 1528], 'Glia,': [517, 535, 571, 662, 1418], '11:': [518], '336–344.': [519], 'Banati,': [520, 538], 'R.': [521, 539, 873, 1367], 'B.,': [522, 526, 540, 610, 731, 783, 1000, 1031, 1035, 1120, 1364, 1441, 1553], 'Gehrmann,': [523, 541, 1012], 'J.,': [524, 542, 544, 598, 631, 677, 679, 760, 787, 902, 1002, 1127, 1387, 1474, 1550, 1581], 'Schubert,': [525], 'Kreutzberg,': [528, 548, 1003, 1098, 1555], 'G.': [529, 549, 706, 1004, 1080, 1099, 1211, 1556, 1611], '(1993)': [531, 791, 966], 'Cytotoxicity': [532], '7:': [536, 1096], '111–118.': [537], 'Lannes-Vieira,': [543, 1001], 'Wekerle,': [545, 1006], 'H.,': [546, 637, 933, 1007, 1205, 1391, 1585], '(1995)': [551, 645, 1241, 1396, 1485, 1589], 'Inflammatory': [552], 'reaction': [553, 1247], 'experimental': [555, 659, 1023], 'autoimmune': [556, 660, 1024, 1408], 'encephalomyelitis': [557], '(EAE)': [558], 'accompanied': [560], 'βA4-amyloid': [567], 'precursor': [568], '(APP).': [570], '14:': [572, 1419], '209–215.': [573], 'Barnes,': [574], 'P.': [575, 676, 782, 930, 1009, 1037, 1122, 1202, 1363, 1449], 'Karin,': [578], '(1997)': [580, 684, 1042, 1275], 'Nuclear': [581], 'factor-kB:': [582], 'A': [583, 1103, 1277, 1297, 1601, 1623], 'pivotal': [584], 'chronic': [588], 'diseases.': [590], 'N.': [591, 1422], 'Engl.': [592], 'Med.,': [594, 1466], '336:': [595], '1066–1071.': [596], 'Strauss,': [599], 'S.,': [600, 701, 928, 935, 1207], 'Schreiter-Gasser,': [601], 'U.,': [602, 604, 785, 1332, 1358], 'Ganter,': [603, 784], 'Schlegel,': [605], 'P.,': [606, 737, 960, 962, 1184], 'Witt,': [607], 'I.,': [608, 633, 958], 'Volk,': [609, 1034], 'Berger,': [612, 673, 1124], '(1991)': [614, 1293, 1424, 1518], 'Interleukin-6': [615], 'alpha2-macroglobulin': [617], 'indicate': [618], 'an': [619], 'acute-phase': [620], 'state': [621], "Alzheimer's": [623, 863, 949, 1217, 1490, 1542, 1544], 'disease': [624, 864], 'cortices.': [625], 'FEBS': [626], 'Lett.,': [627, 896, 1530], '285:': [628], '111–114.': [629], 'Huitinga,': [632], 'Zhao,': [634], 'W.,': [635, 1005, 1446], 'Lassmann,': [636, 1390], 'Hickey,': [638, 1393], 'Dijkstra,': [642], 'The': [646], 'macrophages,': [649], 'perivascular': [650, 1564], 'cells,': [651], 'cells': [654, 717, 1090, 1567], 'pathogenesis': [657], 'encephalomyelitis.': [661, 1025], '15:': [663, 1505], '437–446.': [664], 'K.': [667, 845, 1274, 1340, 1479, 1483], 'A.,': [668, 837, 842, 874, 904, 1010, 1038, 1077, 1123, 1385, 1471, 1477, 1480], 'Lieb,': [669, 1115], 'K.,': [670, 672, 1116, 1510, 1644], 'Schulze-Osthoff,': [671], 'M.,': [674, 699, 812, 834, 1033, 1073, 1125, 1180, 1233, 1336, 1389, 1508, 1514], 'Gebicke-Haerter,': [675, 899], 'B.': [682, 726, 816, 1130, 1165, 1643], 'Expression': [685, 792, 1559], 'regulation': [687, 986], 'cyclooxygenase-2': [689], 'Eur.': [693], 'Biochem.,': [695], '243:': [696], '726–731.': [697], 'Buttini,': [698], 'Limonta,': [700], 'Boddeke,': [703], 'H.': [704, 907], '(1996)': [708, 741, 817, 847, 1101, 1132, 1536, 1653], 'Peripheral': [709], 'administration': [710], 'lipopolysaccaride': [712], 'activation': [714, 743, 1460, 1656], 'brain.': [720, 1432], 'Neurochem.': [721, 994, 1094], 'Int.,': [722, 1095], '29:': [723], '25–35.': [724], 'Carter,': [725], 'Kaltschmidt,': [728, 730, 997, 999, 1030, 1040, 1117, 1119, 1273], 'C.,': [729, 876, 998, 1118], 'Offenhäuser,': [732], 'N.,': [733, 839, 1227, 1444, 1512], 'Böhm-Matthaei,': [734], 'R.,': [735, 1075, 1182, 1439], 'Baeuerle,': [736, 1008, 1036, 1448], 'Barde,': [739], 'Y.-A.': [740], 'Selective': [742], 'NF-kB': [745, 1017, 1045], 'through': [750], 'receptor': [753], 'p75.': [754], 'Science,': [755], '272:': [756], '542–545.': [757], 'Davies,': [758], 'E.': [759, 767, 811, 1210, 1473, 1652], 'Foster,': [761], 'T.': [762], 'Thomas,': [765], 'Cellular': [769], 'forms': [770], 'functions': [772], 'brain': [774, 1191, 1251, 1496, 1527, 1634], 'Brain': [776, 818, 868, 1167, 1264, 1379], 'Res.': [777], 'Bull.,': [778], '34:': [779], '73–78.': [780], 'Ehrhard,': [781, 1362], 'U.': [790, 879, 1292, 1614], 'functional': [794], 'trk': [795], 'protooncogene': [796], 'human': [798, 1152], 'monocytes.': [799], 'Proc.': [800, 1065], 'Natl.': [801, 1066], 'Acad.': [802, 1067], 'Sci.': [803, 1068], 'USA,': [804, 1069], '90:': [805], '5423–5427.': [806], 'Elkabes,': [807], 'S.': [808, 836, 1470, 1517], 'T.,': [809], 'DiCicco-Bloom,': [810], 'Black,': [814], 'I.': [815, 1316], 'microglia/macrophages': [819], 'express': [820], 'neurotrophins': [821], 'that': [822], 'selectively': [823], 'regulate': [824], 'proliferation': [826], 'function.': [828, 1286], '16:': [831, 1223], '2508–2521.': [832], 'Fahnestock,': [833], 'Scott,': [835, 1469], 'Jetté,': [838], 'Weingartner,': [840, 1475], 'Crutcher,': [844, 1482], 'A.': [846, 1187, 1270, 1315, 1368, 1450, 1484], 'Nerve': [848, 1294, 1486, 1537], 'levels': [854, 1493], 'measured': [855], 'same': [858], 'tissue': [859], 'from': [860, 892, 1060], 'normal': [861], 'parietal': [865], 'cortex.': [866], 'Mol.': [867], 'Res.,': [869, 1265, 1380, 1545], '42:': [870], '175–178.': [871], 'Gadient,': [872, 1366], 'Cron,': [875], '(1990)': [880], 'Interleukin-1α': [881], 'tumor': [883, 1146], 'necrosis': [884, 1147], 'factor-α': [885], 'synergistically': [886], 'stimulate': [887], 'cultured': [893, 1526], 'astrocytes.': [894], 'Neurosci.': [895, 1353, 1529], '117:': [897], '335–340.': [898], 'P.-J.,': [900], 'Schobert,': [903], 'Northoff,': [906], '(1989)': [908, 939, 1188, 1212, 1558], 'Lipopolysaccharide': [909], 'free': [910], 'conditions': [911], 'primary': [913, 1049, 1092], 'astrocyte': [914], 'cultures': [915], 'allow': [916], 'isolation': [919], 'micriglial': [921], 'cells.': [922, 1463], '9:': [925], '183–194.': [926], 'Itagaki,': [927, 1206], 'McGeer,': [929, 1201, 1209], 'Akiyama,': [932, 1204], 'Zhu,': [934], 'Selkoe,': [937], 'Relationship': [940], 'astrocytes': [944], 'amyloid': [946, 1052], 'deposits': [947], 'disease.': [950, 1064, 1218, 1543], 'Neuroimmunol.,': [952, 1027], '24:': [953], '173–182.': [954], 'Jehan,': [955], 'Neveu,': [957], 'Naveilhan,': [959], 'Brachet,': [961, 1183], 'Wion,': [964], 'Complex': [967], 'interactions': [968], 'among': [969], 'second': [970], 'messenger': [971], 'pathways,': [972], 'steroid': [973], 'hormones,': [974], 'protooncogenes': [976], 'fos': [979], 'jun': [981], 'families': [982], 'converge': [983], 'gene.': [992], '60:': [995], '1843–1853.': [996], 'Transcription': [1015, 1043], '55:': [1028], '99–106.': [1029], 'Uherek,': [1032], 'neurons': [1050, 1056], 'peptides': [1053], 'surrounding': [1057], 'early': [1058], 'plaques': [1059], 'patients': [1061], 'Alzheimer': [1063], '94:': [1070], '2642–2647.': [1071], 'Keller,': [1072], 'Jackisch,': [1074], 'Seregi,': [1076], 'Hertting,': [1079], '(1985)': [1081], 'Comparison': [1082], 'prostanoid': [1084], 'forming': [1085], 'capacity': [1086], 'astroglia': [1089], 'culture.': [1093], '655–665.': [1097], 'Microglia:': [1102], 'sensor': [1104], 'pathological': [1106], 'events': [1107, 1243], 'Trends': [1111, 1287, 1433], '19:': [1113], '312–318.': [1114], 'Baeurle,': [1121], 'Interleukin-1β': [1133], 'uses': [1134], 'common': [1135], 'distinct': [1137], 'induction': [1141, 1661], 'interleukin-6': [1144], 'α': [1148], 'genes': [1149], 'astrocytoma': [1153], 'line': [1155], 'U373.': [1156], 'Neurochem.,': [1158, 1639], '66:': [1159], '1496–1503.': [1160], 'Mallat,': [1161, 1179], 'Chamak,': [1164], 'macrophages:': [1168], 'Neurotoxic': [1169], 'effector': [1172], 'cells?': [1173], 'Leuk.': [1175], 'Biol.,': [1176, 1198], '56:': [1177], '416–422.': [1178], 'Houlgatte,': [1181], 'Prochiantz,': [1186], 'Lipopolysaccharide-stimulated': [1189], 'vitro.': [1196], 'Dev.': [1197], '133:': [1199], '309–311.': [1200], 'Immune': [1213], 'Can.': [1219], 'Neurol.': [1221], 'Sci.,': [1222, 1435], '516–527.': [1224], 'Montero-Menei,': [1225], 'Sindji,': [1228], 'Garcion,': [1230], 'E.,': [1231, 1237], 'Mege,': [1232], 'Couez,': [1234], 'Gamelin,': [1236], 'Darcy,': [1239], 'F.': [1240, 1395, 1583, 1588], 'Early': [1242], 'intracerebral': [1254], 'injection:': [1255], 'Relative': [1256], 'contribution': [1257], 'peripheral': [1259, 1636], 'monocyte': [1260], '724:': [1266], '55–66.': [1267], "O'Neill,": [1268], 'NF-kB:': [1276], 'crucial': [1278], 'glial': [1282], '20:': [1289], '252–258.': [1290], 'factor:': [1296, 1622], 'system.': [1307], 'In:': [1308], 'Towards': [1309], 'New': [1311, 1327], 'Pharmacotherapy': [1312], 'Pain.': [1314], 'Basbaum': [1317], 'Beeson,': [1321], 'eds.': [1322], 'John': [1323], '&': [1325], 'Sons,': [1326], 'York,': [1328], 'pp.': [1329], '353–363.': [1330], 'Weskamp,': [1333, 1610], 'Hardung,': [1335], 'Meyer,': [1338], '(1987)': [1341, 1615], 'Synthesis': [1342], 'macrophages.': [1351], 'Soc.': [1352], 'Abstr.,': [1354], '13:': [1355], '184.': [1356], 'Scully,': [1359], 'Neurotrophins:': [1370], 'Signals': [1371], 'systems.': [1377], 'Prog.': [1378], '103:': [1381], '293–305.': [1382], 'Rinner,': [1383], 'Schmidts,': [1388], 'Resident': [1397], 'hematogenous': [1400], 'phagocytes': [1403], 'adoptively': [1405], 'transferred': [1406], 'experemental': [1407], 'encephalomyelitis:': [1409], 'An': [1410, 1616], 'investigation': [1411], 'using': [1412], 'radiation': [1414], 'bone': [1415], 'marrow': [1416], 'chimeras.': [1417], '257–266.': [1420], 'Rothwell,': [1421], 'Function': [1425], 'mechanisms': [1427, 1628], 'interleukin-1': [1429], 'Pharmacol.': [1434], '430–435.': [1437], 'Schreck,': [1438], 'Meier,': [1440], 'Männel,': [1442], 'Dröge,': [1445], 'Dithiocarbamates': [1452], 'potent': [1454], 'inhibitors': [1455], 'nuclear': [1457, 1671], 'kB': [1459], 'intact': [1462], 'Exp.': [1465, 1573], '175:': [1467], '1181–1194.': [1468], 'Mufson,': [1472], 'Skau,': [1478], 'disease:': [1491], 'Increased': [1492], 'throughout': [1494], 'coupled': [1497], 'declines': [1499], 'nucleus': [1501], 'basalis.': [1502], '6213–6221.': [1506], 'Shimojo,': [1507], 'Nakajima,': [1509], 'Takei,': [1511], 'Hamanoue,': [1513], 'Kohsaka,': [1516], 'Production': [1519], 'basic': [1521], 'fibroblast': [1522], '123:': [1531], '229–231.': [1532], 'Sofroniew,': [1533], 'V.': [1535], 'factor,': [1539], 'ageing': [1540], '2:': [1546], '7–14.': [1547], 'Streit,': [1548], 'Graeber,': [1551], 'Ia': [1561], 'antigen': [1562], 'after': [1568], 'sublethal': [1569], 'motor': [1570], 'neuron': [1571], 'injury.': [1572], 'Neurol.,': [1574], '105:': [1575], '115–126.': [1576], 'Van': [1577], 'Dam,': [1578], 'A.-M.,': [1579], 'Tilders,': [1582], 'Berkenbosch,': [1587], 'Endotoxin-induced': [1590], 'appearance': [1591], 'immunoreactive': [1593], 'interleukin-1β': [1594], 'ramified': [1596], 'brain:': [1600], 'light': [1602], 'electron': [1604], 'microscopic': [1605], 'study.': [1606], 'Neuroscience,': [1607], '65:': [1608], '815–826.': [1609], 'enzyme-linked': [1617], 'immunoassay': [1618], 'tool': [1624], 'studying': [1626], 'regulatory': [1627], 'production': [1632], 'tissues.': [1637], '48:': [1640], '1779–1786.': [1641], 'Yoza,': [1642], 'Hu,': [1645], 'Y.': [1647], 'Q.,': [1648], 'McCall,': [1650], 'Protein-tyrosine': [1654], 'kinase': [1655], 'required': [1658], 'interleukin': [1663], '1beta': [1664], 'NFkappaB': [1666, 1670], 'activation,': [1667], 'but': [1668], 'not': [1669], 'translocation.': [1672], 'Biol.': [1674], 'Chem.,': [1675], '271:': [1676], '18306–18309.': [1677], 'Citing': [1678], 'Literature': [1679], 'Volume22,': [1680], 'Issue4April': [1681], '1998Pages': [1682], 'ReferencesRelatedInformation': [1684]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2078193667', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-01T03:33:59.373348', 'created_date': '2016-06-24'}