Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2077588346', 'doi': 'https://doi.org/10.1002/1097-0142(19870115)59:2<213::aid-cncr2820590206>3.0.co;2-i', 'title': 'Elevation of CA 125 in patients with benign and malignant ascites', 'display_name': 'Elevation of CA 125 in patients with benign and malignant ascites', 'publication_year': 1987, 'publication_date': '1987-01-15', 'ids': {'openalex': 'https://openalex.org/W2077588346', 'doi': 'https://doi.org/10.1002/1097-0142(19870115)59:2<213::aid-cncr2820590206>3.0.co;2-i', 'mag': '2077588346', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3026603'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1097-0142(19870115)59:2<213::aid-cncr2820590206>3.0.co;2-i', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S126033908', 'display_name': 'Cancer', 'issn_l': '0008-543X', 'issn': ['0008-543X', '1045-7410', '1097-0142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100714764', 'display_name': 'Jean‐François Bergmann', 'orcid': 'https://orcid.org/0000-0001-6861-9748'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-François Bergmann', 'raw_affiliation_strings': ['Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113625736', 'display_name': 'Jean‐Michel Bidart', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-Michel Bidart', 'raw_affiliation_strings': ['Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5104882305', 'display_name': 'Martine George', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Martine George', 'raw_affiliation_strings': ['Département de Gynécologie, Institut Gustave-Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Gynécologie, Institut Gustave-Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108349082', 'display_name': 'Michel Beaugrand', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149664', 'display_name': 'Hôpital Jean-Verdier', 'ror': 'https://ror.org/04pag4b70', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210149664']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Michel Beaugrand', 'raw_affiliation_strings': ["Service d'Hépatogastro-Entérologie, Hǒpital Jean Verdier, Bondy, France"], 'affiliations': [{'raw_affiliation_string': "Service d'Hépatogastro-Entérologie, Hǒpital Jean Verdier, Bondy, France", 'institution_ids': ['https://openalex.org/I4210149664']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103981369', 'display_name': 'Victor Levy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210102928', 'display_name': 'Hôpital Saint-Antoine', 'ror': 'https://ror.org/01875pg84', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210102928']}, {'id': 'https://openalex.org/I39804081', 'display_name': 'Sorbonne Université', 'ror': 'https://ror.org/02en5vm52', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I39804081']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Victor G. Levy', 'raw_affiliation_strings': ["Service d'Hépatogastro-Entérologie, Hǒpital Saint-Antoine, Paris"], 'affiliations': [{'raw_affiliation_string': "Service d'Hépatogastro-Entérologie, Hǒpital Saint-Antoine, Paris", 'institution_ids': ['https://openalex.org/I4210102928', 'https://openalex.org/I39804081']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036806632', 'display_name': 'Claude Bohuon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Claude Bohuon', 'raw_affiliation_strings': ['Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie Clinique, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4740, 'currency': 'USD', 'value_usd': 4740, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 9.279, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 147, 'citation_normalized_percentile': {'value': 0.984462, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '59', 'issue': '2', 'first_page': '213', 'last_page': '217'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10550', 'display_name': 'Ovarian cancer diagnosis and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10550', 'display_name': 'Ovarian cancer diagnosis and treatment', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11495', 'display_name': 'Animal Virus Infections Studies', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/1103', 'display_name': 'Animal Science and Zoology'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11348', 'display_name': 'Celiac Disease Research and Management', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2715', 'display_name': 'Gastroenterology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-antigen', 'display_name': 'Cancer antigen', 'score': 0.77369356}], 'concepts': [{'id': 'https://openalex.org/C2780496750', 'wikidata': 'https://www.wikidata.org/wiki/Q193889', 'display_name': 'Ascites', 'level': 2, 'score': 0.96272194}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8813834}, {'id': 'https://openalex.org/C2777214474', 'wikidata': 'https://www.wikidata.org/wiki/Q147778', 'display_name': 'Cirrhosis', 'level': 2, 'score': 0.8407906}, {'id': 'https://openalex.org/C2992389814', 'wikidata': 'https://www.wikidata.org/wiki/Q2459684', 'display_name': 'Cancer antigen', 'level': 3, 'score': 0.77369356}, {'id': 'https://openalex.org/C2778019345', 'wikidata': 'https://www.wikidata.org/wiki/Q1148337', 'display_name': 'Hepatocellular carcinoma', 'level': 2, 'score': 0.71029973}, {'id': 'https://openalex.org/C2780427987', 'wikidata': 'https://www.wikidata.org/wiki/Q172341', 'display_name': 'Ovarian cancer', 'level': 3, 'score': 0.6582564}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.6397503}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.62740517}, {'id': 'https://openalex.org/C3019054536', 'wikidata': 'https://www.wikidata.org/wiki/Q172341', 'display_name': 'Ovarian carcinoma', 'level': 4, 'score': 0.49192786}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.45114255}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.32024473}], 'mesh': [{'descriptor_ui': 'D000951', 'descriptor_name': 'Antigens, Neoplasm', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D001201', 'descriptor_name': 'Ascites', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D008103', 'descriptor_name': 'Liver Cirrhosis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D010051', 'descriptor_name': 'Ovarian Neoplasms', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000951', 'descriptor_name': 'Antigens, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000951', 'descriptor_name': 'Antigens, Neoplasm', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D015295', 'descriptor_name': 'Antigens, Tumor-Associated, Carbohydrate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001201', 'descriptor_name': 'Ascites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D006528', 'descriptor_name': 'Carcinoma, Hepatocellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008103', 'descriptor_name': 'Liver Cirrhosis', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008103', 'descriptor_name': 'Liver Cirrhosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008113', 'descriptor_name': 'Liver Neoplasms', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008581', 'descriptor_name': 'Meningitis', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008581', 'descriptor_name': 'Meningitis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D008581', 'descriptor_name': 'Meningitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010051', 'descriptor_name': 'Ovarian Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010051', 'descriptor_name': 'Ovarian Neoplasms', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D010195', 'descriptor_name': 'Pancreatitis', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D010195', 'descriptor_name': 'Pancreatitis', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D010195', 'descriptor_name': 'Pancreatitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010956', 'descriptor_name': 'Plasmapheresis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1097-0142(19870115)59:2<213::aid-cncr2820590206>3.0.co;2-i', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S126033908', 'display_name': 'Cancer', 'issn_l': '0008-543X', 'issn': ['0008-543X', '1045-7410', '1097-0142'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3026603', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.86, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 14, 'referenced_works': ['https://openalex.org/W1971062352', 'https://openalex.org/W1978246084', 'https://openalex.org/W1981177685', 'https://openalex.org/W2030146379', 'https://openalex.org/W2054327319', 'https://openalex.org/W2091060772', 'https://openalex.org/W2093252833', 'https://openalex.org/W2095877854', 'https://openalex.org/W2102719470', 'https://openalex.org/W2150087209', 'https://openalex.org/W2414703600', 'https://openalex.org/W2415213915', 'https://openalex.org/W2417919851', 'https://openalex.org/W59117347'], 'related_works': ['https://openalex.org/W4249977521', 'https://openalex.org/W3029888474', 'https://openalex.org/W2414281636', 'https://openalex.org/W2377767392', 'https://openalex.org/W2368857971', 'https://openalex.org/W2364855749', 'https://openalex.org/W22345929', 'https://openalex.org/W2160370110', 'https://openalex.org/W2077588346', 'https://openalex.org/W2031415086'], 'abstract_inverted_index': {'The': [0, 74, 107], 'presence': [1], 'of': [2, 36, 44, 51, 60, 78, 117, 127, 141, 148], 'CA': [3, 38, 67, 79, 96, 111, 128, 137], '125,': [4], 'an': [5], 'ovarian': [6, 18, 45, 134], 'cancer-associated': [7], 'antigen,': [8], 'was': [9, 99], 'assessed': [10], 'in': [11, 42, 49, 85, 102, 105, 124, 131, 143], 'serum': [12, 37], 'and': [13, 28, 48, 76, 91, 146], 'ascites': [14, 84, 103], 'from': [15], 'patients': [16, 54, 132], 'with': [17, 55, 65, 133], 'cancer': [19, 46], '(n': [20, 25, 31], '=': [21, 26, 32], '47),': [22], 'hepatocellular': [23, 63], 'carcinoma': [24, 64], '21),': [27], 'liver': [29, 87], 'cirrhosis': [30, 61], '40).': [33], 'Abnormal': [34], 'levels': [35, 69], '125': [39, 68, 80, 97, 112, 129, 138], 'were': [40, 70, 89], 'observed': [41], '49%': [43], 'patients,': [47], '89%': [50], 'these': [52], 'same': [53], 'ascites.': [56, 118], 'In': [57], 'all': [58], 'cases': [59], 'or': [62], 'ascites,': [66], 'above': [71], '35': [72], 'U/ml.': [73], 'specificity': [75], 'sensitivity': [77], 'measurement': [81], 'for': [82], 'detecting': [83], 'chronic': [86], 'diseases': [88], '73%': [90], '100%,': [92], 'respectively.': [93], 'Furthermore,': [94], 'the': [95, 125, 144], 'level': [98], 'always': [100], 'higher': [101], 'than': [104], 'serum.': [106], 'authors': [108], 'conclude': [109], 'that': [110], 'is': [113], 'a': [114], 'nonspecific': [115], 'marker': [116], 'This': [119], 'result': [120], 'must': [121], 'be': [122, 140], 'considered': [123], 'interpretation': [126], 'elevation': [130], 'cancer.': [135], 'Moreover,': [136], 'may': [139], 'value': [142], 'diagnosis': [145], 'monitoring': [147], 'peritoneal': [149], 'diseases.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2077588346', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-12T10:28:45.492169', 'created_date': '2016-06-24'}