Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2077318355', 'doi': 'https://doi.org/10.1002/jmor.1052220305', 'title': 'Effects of anisosmotic conditions on the cytoskeletal architecture of cultured PC12 cells', 'display_name': 'Effects of anisosmotic conditions on the cytoskeletal architecture of cultured PC12 cells', 'publication_year': 1994, 'publication_date': '1994-12-01', 'ids': {'openalex': 'https://openalex.org/W2077318355', 'doi': 'https://doi.org/10.1002/jmor.1052220305', 'mag': '2077318355', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7837276'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jmor.1052220305', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S173450624', 'display_name': 'Journal of Morphology', 'issn_l': '0362-2525', 'issn': ['0362-2525', '1097-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5072283568', 'display_name': 'M. Cornet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I149768937', 'display_name': 'University of Namur', 'ror': 'https://ror.org/03d1maw17', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I149768937']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Michèle Cornet', 'raw_affiliation_strings': ['Laboratory of Compared Biochemistry and Physiology, Facultés, Universitaires Notre-Dame de la Paix, Namur, Belgium.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Compared Biochemistry and Physiology, Facultés, Universitaires Notre-Dame de la Paix, Namur, Belgium.', 'institution_ids': ['https://openalex.org/I149768937']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045033003', 'display_name': 'Y Isobe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I70983195', 'display_name': 'Syracuse University', 'ror': 'https://ror.org/025r5qe02', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I70983195']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yuji Isobe', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, State University of New York, Health Science Center at Syracuse, Syracuse, New York 13210'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, State University of New York, Health Science Center at Syracuse, Syracuse, New York 13210', 'institution_ids': ['https://openalex.org/I1327163397', 'https://openalex.org/I70983195']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5004757150', 'display_name': 'Larry F. Lemanski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I70983195', 'display_name': 'Syracuse University', 'ror': 'https://ror.org/025r5qe02', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I70983195']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Larry F. Lemanski', 'raw_affiliation_strings': ['Department of Anatomy and Cell Biology, SUNY Health Science Center at Syracuse, 750 East Adams Street, Syracuse, NY 13210', 'Department of Anatomy and Cell Biology, State University of New York‐Health Science Center at Syracuse, Syracuse, New York 13210'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Cell Biology, State University of New York‐Health Science Center at Syracuse, Syracuse, New York 13210', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': 'Department of Anatomy and Cell Biology, SUNY Health Science Center at Syracuse, 750 East Adams Street, Syracuse, NY 13210', 'institution_ids': ['https://openalex.org/I70983195']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.699746, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '222', 'issue': '3', 'first_page': '269', 'last_page': '286'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10379', 'display_name': 'Cell Mechanics and Extracellular Matrix Interactions', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10379', 'display_name': 'Cell Mechanics and Extracellular Matrix Interactions', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Mechanosensitive Ion Channels in Physiology and Disease', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11650', 'display_name': 'Biology and Pathology of Keratins and Related Disorders', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/osmotic-concentration', 'display_name': 'Osmotic concentration', 'score': 0.53981864}, {'id': 'https://openalex.org/keywords/phalloidin', 'display_name': 'Phalloidin', 'score': 0.5240084}, {'id': 'https://openalex.org/keywords/cytoskeleton', 'display_name': 'Cytoskeleton', 'score': 0.518277}], 'concepts': [{'id': 'https://openalex.org/C189040839', 'wikidata': 'https://www.wikidata.org/wiki/Q329638', 'display_name': 'Microfilament', 'level': 4, 'score': 0.9285466}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.77428484}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.75711983}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.70007586}, {'id': 'https://openalex.org/C20418707', 'wikidata': 'https://www.wikidata.org/wiki/Q189933', 'display_name': 'Microtubule', 'level': 2, 'score': 0.6937013}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6895529}, {'id': 'https://openalex.org/C125705527', 'wikidata': 'https://www.wikidata.org/wiki/Q185269', 'display_name': 'Actin', 'level': 2, 'score': 0.66950667}, {'id': 'https://openalex.org/C129900496', 'wikidata': 'https://www.wikidata.org/wiki/Q643555', 'display_name': 'Osmotic concentration', 'level': 2, 'score': 0.53981864}, {'id': 'https://openalex.org/C2776861759', 'wikidata': 'https://www.wikidata.org/wiki/Q2266164', 'display_name': 'Phalloidin', 'level': 4, 'score': 0.5240084}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5170944}, {'id': 'https://openalex.org/C78383274', 'wikidata': 'https://www.wikidata.org/wiki/Q421987', 'display_name': 'Intermediate filament', 'level': 4, 'score': 0.43215045}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.3202111}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16030246}], 'mesh': [{'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': True}, {'descriptor_ui': 'D008841', 'descriptor_name': 'Actin Cytoskeleton', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008841', 'descriptor_name': 'Actin Cytoskeleton', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008854', 'descriptor_name': 'Microscopy, Electron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008855', 'descriptor_name': 'Microscopy, Electron, Scanning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009997', 'descriptor_name': 'Osmotic Pressure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016716', 'descriptor_name': 'PC12 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jmor.1052220305', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S173450624', 'display_name': 'Journal of Morphology', 'issn_l': '0362-2525', 'issn': ['0362-2525', '1097-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7837276', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W112121826', 'https://openalex.org/W1507577640', 'https://openalex.org/W1607116311', 'https://openalex.org/W168130471', 'https://openalex.org/W188400125', 'https://openalex.org/W1968577363', 'https://openalex.org/W1974091049', 'https://openalex.org/W1984864591', 'https://openalex.org/W1997538204', 'https://openalex.org/W2004952617', 'https://openalex.org/W2007514006', 'https://openalex.org/W2013799789', 'https://openalex.org/W2014487236', 'https://openalex.org/W2019250628', 'https://openalex.org/W2030406466', 'https://openalex.org/W2036217876', 'https://openalex.org/W2038804800', 'https://openalex.org/W2038883138', 'https://openalex.org/W2056824894', 'https://openalex.org/W2059962391', 'https://openalex.org/W2072543637', 'https://openalex.org/W2082675476', 'https://openalex.org/W2087180568', 'https://openalex.org/W2088088901', 'https://openalex.org/W2091531560', 'https://openalex.org/W2112871452', 'https://openalex.org/W2116367177', 'https://openalex.org/W2118864235', 'https://openalex.org/W2125295799', 'https://openalex.org/W2125942201', 'https://openalex.org/W2131996349', 'https://openalex.org/W2144707785', 'https://openalex.org/W2158352050', 'https://openalex.org/W2166241889', 'https://openalex.org/W2184944689', 'https://openalex.org/W2210034751', 'https://openalex.org/W2286893858', 'https://openalex.org/W2415905438', 'https://openalex.org/W2416546976', 'https://openalex.org/W2426657998', 'https://openalex.org/W2428837113', 'https://openalex.org/W2430023751', 'https://openalex.org/W2469666795', 'https://openalex.org/W25348686', 'https://openalex.org/W41948340', 'https://openalex.org/W4232513362', 'https://openalex.org/W4250800175', 'https://openalex.org/W4388386538', 'https://openalex.org/W570513639'], 'related_works': ['https://openalex.org/W4231963622', 'https://openalex.org/W2433757165', 'https://openalex.org/W2412785979', 'https://openalex.org/W2206959264', 'https://openalex.org/W2131047811', 'https://openalex.org/W2076486638', 'https://openalex.org/W2047725503', 'https://openalex.org/W2019648872', 'https://openalex.org/W1986383730', 'https://openalex.org/W1866125244'], 'abstract_inverted_index': {'Abstract': [0], 'PC12': [1, 113, 182], 'cells': [2, 114], 'show': [3], 'a': [4, 120, 125, 146, 167], 'classical': [5], 'volume': [6, 57, 137], 'regulatory': [7, 138], 'process': [8], 'when': [9], 'submitted': [10], 'to': [11, 101, 103], 'hypo‐osmotic': [12, 204], 'conditions.': [13, 205], 'The': [14, 87, 140], 'present': [15], 'study': [16], 'examined': [17], 'the': [18, 25, 51, 64, 67, 73, 85, 90, 97, 104, 109, 150, 154, 157, 161, 172, 181, 190, 203], 'effects': [19], 'of': [20, 28, 37, 66, 80, 108, 112, 127, 142, 148, 156, 164, 176, 189], 'such': [21], 'osmotic': [22, 165], 'shock': [23], 'on': [24], 'structural': [26], 'organization': [27, 65], 'different': [29, 38], 'cytoskeletal': [30], 'elements.': [31], 'Results': [32], 'were': [33, 58, 89, 199], 'obtained': [34], 'by': [35, 124, 202], 'use': [36], 'light': [39], 'and': [40, 99, 136, 153, 174, 195], 'electron': [41], 'microscopy': [42], 'techniques': [43], 'combined': [44], 'with': [45, 60, 116, 133], 'immunostaining': [46], 'methods.': [47], 'It': [48], 'appeared': [49], 'that': [50], 'osmotically': [52], 'induced': [53], 'changes': [54], 'in': [55, 63, 72, 84, 96, 131, 171], 'cell': [56, 183], 'concomitant': [59], 'important': [61], 'modifications': [62], 'microfilament': [68, 134, 143, 192], 'network.': [69, 193], 'Microfilaments': [70], 'concentrated': [71], 'perinuclear': [74], 'area,': [75], 'leaving': [76], 'only': [77, 91], 'radial': [78], 'extensions': [79], 'poorly': [81], 'organized': [82], 'structures': [83, 93], 'cytoplasm.': [86], 'latter': [88], 'actin': [92], 'immunologically': [94], 'stained': [95], 'cytoplasm': [98], 'seemed': [100], 'anchor': [102], 'plasma': [105], 'membrane.': [106], 'Measurements': [107], 'fluorescence': [110], 'intensity': [111], 'treated': [115], 'FITC‐labeled': [117], 'phalloidin': [118], 'indicated': [119], 'progressive': [121], 'depolymerization,': [122], 'followed': [123], 'repolymerization': [126], 'F‐actin.': [128], 'This': [129], 'occurs': [130], 'parallel': [132], 'reorganization': [135, 144, 188], 'processes.': [139], 'appearance': [141], 'was': [145, 169], 'function': [147], 'both': [149], 'incubation': [151], 'period': [152], 'amplitude': [155], 'osmolarity': [158], 'changes.': [159], 'During': [160], 'first': [162], 'minutes': [163], 'shock,': [166], 'decrease': [168], 'observed': [170], 'density': [173], 'length': [175], 'microvilli,': [177], 'which': [178], 'normally': [179], 'cover': [180], 'surfaces,': [184], 'suggesting': [185], 'an': [186], 'early': [187], 'underlying': [191], 'Microtubules': [194], 'intermediate': [196], 'filament': [197], 'networks': [198], 'not': [200], 'affected': [201], '©': [206], '1994': [207], 'Wiley‐Liss,': [208], 'Inc.': [209]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2077318355', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-08T17:03:44.397705', 'created_date': '2016-06-24'}