Publication Information

{'id': 'https://openalex.org/W2077037330', 'doi': 'https://doi.org/10.1248/bpb.20.237', 'title': 'The Preventive Effect of Ginseng with Du-Zhong Leaf on Protein Metabolism in Aging.', 'display_name': 'The Preventive Effect of Ginseng with Du-Zhong Leaf on Protein Metabolism in Aging.', 'publication_year': 1997, 'publication_date': '1997-01-01', 'ids': {'openalex': 'https://openalex.org/W2077037330', 'doi': 'https://doi.org/10.1248/bpb.20.237', 'mag': '2077037330', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9084879'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.20.237', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb1993/20/3/20_3_237/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/bpb1993/20/3/20_3_237/_pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5090435111', 'display_name': 'Koichi Metori', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I104946051', 'display_name': 'Nihon University', 'ror': 'https://ror.org/05jk51a88', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I104946051']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Koichi METORI', 'raw_affiliation_strings': ['Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University', 'institution_ids': ['https://openalex.org/I104946051']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073644641', 'display_name': 'Mio FURUTSU', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I104946051', 'display_name': 'Nihon University', 'ror': 'https://ror.org/05jk51a88', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I104946051']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mio FURUTSU', 'raw_affiliation_strings': ['Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University', 'institution_ids': ['https://openalex.org/I104946051']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077803129', 'display_name': 'S. Takahashi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I104946051', 'display_name': 'Nihon University', 'ror': 'https://ror.org/05jk51a88', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I104946051']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shushichi TAKAHASHI', 'raw_affiliation_strings': ['Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University, Department of Biochemistry, College of Pharmacy, Nihon University', 'institution_ids': ['https://openalex.org/I104946051']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.548, 'has_fulltext': False, 'cited_by_count': 34, 'citation_normalized_percentile': {'value': 0.868055, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '20', 'issue': '3', 'first_page': '237', 'last_page': '242'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T14028', 'display_name': 'Healthcare and Venom Research', 'score': 0.7494, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T14028', 'display_name': 'Healthcare and Venom Research', 'score': 0.7494, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12385', 'display_name': 'Food Quality and Safety Studies', 'score': 0.7212, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779232237', 'wikidata': 'https://www.wikidata.org/wiki/Q20817212', 'display_name': 'Ginseng', 'level': 3, 'score': 0.8160141}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.48664483}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.4714414}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.400639}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38291}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.37684685}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.27729845}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.10312274}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005894', 'descriptor_name': 'Panax', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018515', 'descriptor_name': 'Plant Leaves', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D010946', 'descriptor_name': 'Plants, Medicinal', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003094', 'descriptor_name': 'Collagen', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D003094', 'descriptor_name': 'Collagen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004032', 'descriptor_name': 'Diet', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006099', 'descriptor_name': 'Granuloma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006099', 'descriptor_name': 'Granuloma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006099', 'descriptor_name': 'Granuloma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018515', 'descriptor_name': 'Plant Leaves', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010946', 'descriptor_name': 'Plants, Medicinal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.20.237', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb1993/20/3/20_3_237/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9084879', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.20.237', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb1993/20/3/20_3_237/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W657579294', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'Stimulation': [0], 'of': [1, 18, 28, 38, 52, 91, 96, 105, 111], 'collagen': [2, 106], 'synthesis': [3, 107], 'prevents': [4], 'the': [5, 16, 26, 65, 88, 99, 103, 109], 'aging': [6], 'process.': [7], 'We': [8, 47], 'found': [9], 'such': [10], 'a': [11, 76], 'synergistic': [12], 'effect': [13, 43], 'by': [14], 'using': [15], 'leaves': [17], 'Eucommia': [19], 'ulmoides': [20], 'Oliver,': [21], 'Eucomiaceae': [22], '(Du-Zhong': [23], 'leaf)': [24], 'and': [25, 54, 60, 62, 81, 108], 'roots': [27], 'Panax': [29], 'ginseng': [30], 'C.': [31], 'A.': [32], 'MEYER': [33], '(Ginseng).': [34], 'The': [35], 'formula': [36, 50, 89], 'consists': [37], 'amounts': [39], 'which': [40], 'exert': [41], 'no': [42], 'when': [44], 'used': [45], 'individually.': [46], 'tested': [48], 'several': [49], 'ratios': [51], 'Ginseng': [53, 92], 'Du-Zhong': [55, 94], 'leaf,': [56], '1:1,': [57], '1:2,': [58], '1:3': [59, 80, 97], '1:4,': [61], 'concluded': [63], 'that': [64, 87], 'last': [66], 'two': [67], 'formulas': [68], 'were': [69], 'effective.': [70], 'However,': [71], 'we': [72], 'did': [73], 'not': [74], 'observe': [75], 'significant': [77], 'difference': [78], 'between': [79], '1:4.': [82], 'Thus,': [83], 'it': [84], 'was': [85, 98], 'demonstrated': [86], 'ratio': [90], 'to': [93], 'leaf': [95], 'most': [100], 'effective': [101], 'for': [102], 'stimulation': [104], 'prevention': [110], 'decreased': [112], 'protein': [113], 'metabolism': [114], 'in': [115], 'aging.': [116]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2077037330', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-11T01:19:50.883935', 'created_date': '2016-06-24'}