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2158, 2191, 2229, 2242, 2250, 2273, 2278, 2350, 2368, 2392, 2402, 2415, 2423, 2449, 2456, 2473, 2481, 2496, 2504, 2519, 2563, 2572, 2592, 2609, 2654, 2666, 2676, 2683, 2714, 2729, 2746, 2761, 2782, 2786, 2809, 2815, 2825, 2834, 2847, 2850, 2892, 2925, 2955, 2958, 2965, 2972, 2978, 2988, 3059, 3076, 3092, 3115, 3166, 3220, 3250, 3272, 3287, 3297, 3354, 3376, 3402, 3405, 3429, 3432, 3437, 3463, 3478, 3527, 3549, 3553, 3557, 3624, 3681, 3703, 3714, 3741, 3767, 3779, 3803, 3825, 3843, 3854, 3858, 3867, 3872, 3896, 3903, 3908, 3934, 3956, 3979, 3987, 4000, 4014, 4018, 4024, 4046, 4054, 4061, 4075, 4095, 4098, 4117, 4123, 4129, 4181, 4186, 4228, 4238, 4246, 4264, 4331, 4353, 4377, 4446, 4468, 4471, 4475, 4482, 4494, 4497, 4514, 4517], 'Ets': [5, 203, 403, 420, 533, 593, 605, 621, 628, 1630, 2192], 'family': [6, 204, 421, 568], 'transcription': [8, 206, 423, 541, 656, 1644], 'factors,': [9, 207], 'is': [10, 46, 53, 95, 191, 208, 244, 251, 293, 389, 577, 616, 770, 823, 935, 1059, 1164, 1283, 1415, 1430, 1620, 1684, 1779, 2007, 2052, 2195, 3188, 4110, 4152, 4367], 'nuclear': [12, 210, 3112, 3657], 'phosphoprotein': [13, 211], 'capable': [14, 212], 'activating': [16, 214], 'transcription.': [17, 215], 'Mouse': [18, 216, 747], 'PEA3': [19, 40, 78, 84, 106, 139, 190, 217, 238, 276, 282, 304, 337, 388, 1163, 1178, 1239, 1250, 1282, 1323, 1636, 1755, 1768, 1791, 1834, 1883, 1891, 2067, 2106, 2182, 2358, 2371, 2406, 2428, 2476, 2499, 2507, 2581, 2655, 2685, 2895, 2968, 3158, 3329, 3439, 3529, 3558, 3688, 3784, 3794, 3829, 3965, 3976, 4106, 4130, 4196, 4270, 4366, 4464, 4498], 'comprises': [20, 218, 2174, 3959], '480': [21, 219, 4454], 'amino': [22, 92, 220, 290, 1051, 1111, 1116, 1130, 1749, 1776, 3222, 3253, 3275, 3919, 4100, 4174, 4267, 4288], 'acids': [23, 221, 1117, 1131, 3254, 3276, 4175, 4268, 4289], 'and': [24, 222, 401, 408, 475, 484, 585, 650, 653, 773, 891, 1121, 1172, 1417, 1625, 1642, 1675, 1686, 1724, 1739, 1750, 1756, 1829, 1863, 1867, 1965, 2014, 2041, 2057, 2115, 2168, 2199, 2238, 2245, 2297, 2319, 2355, 2375, 2407, 2453, 2508, 2539, 2576, 2605, 2771, 2797, 2836, 2884, 2984, 3029, 3034, 3058, 3125, 3141, 3159, 3179, 3191, 3197, 3201, 3214, 3216, 3223, 3231, 3330, 3363, 3384, 3417, 3440, 3450, 3466, 3515, 3651, 3680, 3708, 3732, 3842, 3920, 3938, 4034, 4053, 4080, 4101, 4122, 4158, 4211, 4277, 4291, 4312, 4325, 4343, 4372, 4388, 4430, 4435, 4460, 4477, 4487], 'bears': [25, 85, 223, 283, 1769], 'an': [26, 224, 428, 586, 1106, 2036, 2178, 2373, 2795, 2862, 3448, 3686, 3963, 4253], '∼85-amino': [27, 225, 431], 'acid': [28, 226, 1052, 1100], 'ETS': [29, 44, 148, 175, 227, 242, 346, 373, 432, 583, 635, 1101, 1423, 1427, 1482, 1682, 1823, 4363, 4378, 4499], 'domain': [30, 45, 89, 149, 176, 228, 243, 287, 347, 374, 433, 584, 636, 1102, 1424, 1683, 1773, 2765, 3290, 3379, 4358, 4364, 4379], 'near': [31, 90, 229, 288, 1109, 1774], 'its': [32, 64, 91, 104, 230, 262, 289, 302, 1775, 1789, 1846, 2897, 2970, 3160, 3831], 'carboxyl': [33, 231, 1126, 3224], 'terminus.': [34, 232], 'Whereas': [35, 233], 'analyses': [36, 234, 632, 1765, 4472], 'bacterially': [38, 236], 'expressed': [39, 107, 237, 305, 1673, 1792, 2381, 2410, 2479, 2517, 2689, 2781, 2943, 3929, 3977, 4012], 'revealed': [41, 142, 239, 340, 1766, 2484, 4167], 'that': [42, 100, 143, 186, 240, 298, 341, 384, 539, 643, 970, 1479, 1493, 1613, 1632, 1680, 1767, 1778, 1820, 1839, 2090, 2310, 2491, 2692, 2710, 2792, 2828, 3477, 3995, 4026, 4083, 4107, 4135, 4168, 4191, 4236, 4317, 4321, 4450, 4524], 'required': [47, 62, 159, 245, 260, 357, 1685, 1721], 'for': [48, 63, 179, 246, 261, 377, 609, 619, 1177, 1688, 1722, 2904, 3039, 3046, 3063, 3144, 3661], 'sequence-specific': [49, 180, 247, 378, 536, 1689], 'DNA': [50, 116, 120, 135, 152, 162, 181, 248, 314, 318, 333, 350, 360, 379, 575, 1639, 1690, 1725, 1803, 1830, 2268, 2553, 2621, 2631, 2635, 2727, 2739, 2763, 2865, 3288, 3377, 3507, 3514, 3521, 3704, 3718, 3737, 3744, 3763, 3775, 3789, 3807, 4386, 4500, 4518], 'binding,': [51, 249], 'little': [52, 250, 4328], 'known': [54, 252, 570], 'functional': [57, 79, 196, 255, 277, 394, 3909], 'domains': [58, 80, 256, 278, 3910], 'in': [59, 66, 81, 108, 117, 164, 257, 264, 279, 306, 315, 362, 472, 482, 504, 543, 1166, 1170, 1179, 1286, 1291, 1299, 1329, 1335, 1435, 1674, 1694, 1727, 1760, 1793, 1852, 1876, 2073, 2110, 2204, 2338, 2382, 2462, 2480, 2488, 2503, 2513, 2852, 2869, 2944, 2977, 2990, 3003, 3055, 3138, 3428, 3445, 3484, 3540, 3566, 3696, 3740, 3802, 3838, 3881, 3911, 3930, 4060, 4112, 4141, 4154, 4216, 4256, 4330, 4348, 4359, 4365], 'protein': [61, 259, 649, 2343, 2436, 2857, 2952, 3068, 3097, 3102, 3110, 4059], 'activity': [65, 122, 137, 188, 263, 320, 335, 386, 1486, 1616, 1743, 1805, 2324, 2337, 2395, 2425, 2460, 2490, 2583, 2652, 2681, 2702, 2747, 2784, 2819, 2929, 2941, 2956, 3435, 3746, 3765, 3777, 3791, 4048, 4071, 4125, 4184, 4197, 4230, 4301, 4332, 4382], 'mammalian': [67, 265, 509, 1728, 1761], 'cells.': [68, 83, 266, 281, 1763], 'To': [69, 267, 1734, 2963, 3906], 'this': [70, 268, 573, 612, 1180, 1436, 1735, 2050, 2470, 2514, 3736, 3878, 4177, 4257, 4360], 'end,': [71, 269], 'we': [72, 270, 1737, 2421, 2757, 2780, 3913, 4027], 'defined': [73, 271, 426], 'location': [75, 273, 1718], 'COS': [82, 109, 280, 307, 1762, 1794, 2346, 2443, 2524, 3931], 'strong': [87, 285, 1771], 'activation': [88, 286, 1772, 4254, 4357], 'terminus,': [93, 291], 'which': [94, 292, 1429, 1786, 2091, 2696, 4087], 'flanked': [96, 294, 1780], 'by': [97, 126, 295, 324, 427, 579, 1696, 1781, 1809, 1815, 1889, 1930, 1939, 2101, 2221, 2334, 2387, 2441, 2562, 2627, 2754, 2767, 2808, 2813, 2899, 3000, 3075, 3084, 3120, 3132, 3168, 3239, 3262, 3335, 3710, 3728, 3749, 3773, 4050, 4132, 4223, 4384], 'two': [98, 144, 296, 342, 1782, 1817, 2871, 2885, 3180, 3459, 3821, 4163], 'regions': [99, 145, 157, 297, 343, 355, 1819, 4490], 'independently': [101, 150, 299, 348, 2878, 2888], 'negatively': [102, 300, 1836, 4194, 4462, 4488], 'regulate': [103, 301, 540, 1845, 4195, 4463], 'activity.': [105, 303, 1790, 1847, 4068, 4465], 'cells': [110, 308, 1729, 1795, 1870, 2347, 2444, 2525, 2573, 2822, 2831, 2997, 3480, 3497, 3932], 'was': [111, 158, 177, 309, 356, 375, 1796, 1887, 2219, 2331, 2365, 2439, 2492, 2584, 2622, 2641, 2658, 2688, 2697, 2706, 2718, 2740, 2752, 2777, 2811, 2867, 2930, 2942, 3044, 3061, 3073, 3136, 3237, 3260, 3293, 3333, 3365, 3411, 3443, 3453, 3533, 3561, 3659, 3668, 3691, 3726, 3738, 3747, 3771, 3795, 3879, 3950, 4042, 4078, 4088, 4233, 4271, 4314, 4440], 'incapable': [112, 310, 1797], 'binding': [114, 121, 136, 163, 312, 319, 334, 361, 576, 594, 629, 1691, 1726, 1799, 1804, 1831, 2183, 2193, 2269, 2764, 3289, 3378, 3628, 3663, 3689, 3742, 3745, 3764, 3776, 3790, 3808, 3966, 4387, 4501, 4519], 'to': [115, 160, 313, 358, 478, 571, 623, 625, 642, 1295, 1419, 1638, 1800, 1843, 1953, 2029, 2089, 2143, 2308, 2367, 2390, 2472, 2495, 2643, 2691, 2722, 2742, 2791, 2827, 2880, 2890, 2924, 3127, 3249, 3295, 3391, 3543, 3670, 3700, 3778, 3863, 3886, 3941, 3969, 3990, 4044, 4064, 4082, 4219, 4316, 4339], 'vitro.': [118, 316], 'However,': [119, 317, 1716, 1802, 4335], 'could': [123, 321, 1806, 2758], 'be': [124, 322, 1807], 'unmasked': [125, 323], 'incubation': [127, 325, 1810], 'with': [128, 326, 1622, 1640, 1811, 1858, 2349, 2445, 2546, 2597, 2646, 2669, 2720, 2824, 2833, 2980, 3086, 3150, 3242, 3265, 3286, 3343, 3375, 3413, 3500, 3623, 3713, 3818, 4134, 4202, 4225, 4245, 4352], 'PEA3-specific': [130, 169, 328, 367, 1812, 3185, 3666], 'antibody.': [131, 170, 329, 368], 'Analyses': [132, 330, 1669, 4161], 'deletion': [140, 154, 338, 352, 1752, 1924, 1957, 2033, 2079, 2149, 2510, 2656, 2686, 3559, 3785, 3922, 4103, 4169, 4308, 4426, 4479, 4505], 'mutants': [141, 339, 1753, 1925, 1958, 2034, 2150, 2511, 2657, 2687, 3560, 3923, 4025, 4104, 4131, 4166, 4309, 4427, 4480, 4506], 'flanking': [146, 344, 611, 2239], 'inhibited': [151, 349], 'binding;': [153, 351], 'both': [156, 354, 1169, 1826, 2306, 4474, 4485], 'detect': [161, 359, 2760], 'absence': [166, 364], 'Under': [171, 369], 'these': [172, 370, 559, 933, 1247, 1488, 1618, 2522, 3409, 3671, 3697, 4192, 4439], 'conditions,': [173, 371], 'sufficient': [178, 376, 1687], 'binding.': [182, 380], 'These': [183, 381, 467, 1610, 2206, 3927, 4241], 'findings': [184, 382, 1611], 'suggest': [185, 383], 'exquisitely': [192, 390, 1844], 'controlled': [193, 391], 'at': [194, 392, 1124, 1873, 2411, 2531, 2624, 2699, 3049, 3052, 3147, 3219, 3455, 3488, 3563, 3819, 4013, 4090, 4206], 'multiple': [195, 393], 'levels.': [197, 395], 'polyoma': [396], 'enhancer': [397], 'activator': [398, 648], '3': [399, 3509, 3516, 3538, 3564], '-4,': [400], '-5,': [402], 'translocation': [404, 1434], 'variant': [405], '1,': [406, 4156], '4,': [407], '5,': [409], 'respectively': [410], 'electrophoretic': [411], 'mobility': [412], 'shift': [413], 'assay': [414, 2454, 2934], 'wild': [415, 2417], 'type': [416, 2231, 2418], 'glutathione': [417], 'S-transferase': [418], 'The': [419, 1049, 1089, 1410, 1484, 1869, 1882, 1922, 1950, 2081, 2154, 2257, 2295, 2322, 2506, 2616, 2633, 2651, 2679, 2701, 2734, 2802, 2996, 3042, 3066, 3134, 3184, 3207, 3496, 3524, 3627, 3723, 3761, 3787, 3952, 4007, 4069, 4299, 4362, 4503], 'factors': [424, 657], 'are': [425, 469, 476, 535, 569, 1835, 2019, 2062, 3211, 3899, 4243], 'evolutionarily': [429], 'conserved': [430, 599], '(1Karim': [434], 'F.D.': [435], 'Urness': [436], 'L.D.': [437], 'Thummel': [438], 'C.S.': [439], 'Klemsz': [440, 730, 1575], 'M.J.': [441], 'McKercher': [442, 732], 'S.R.': [443], 'Celada': [444], 'A.': [445, 713, 752, 802, 912, 1000, 1067, 1141, 1217, 1270, 1391, 1460, 1560, 1654, 1701, 1897, 2166, 2170, 2201, 3203, 3608, 4114], 'Van': [446], 'Beveren': [447], 'C.': [448, 519, 1445], 'Maki': [449, 734], 'R.A.': [450, 735, 1510], 'Gunther': [451], 'C.V.': [452], 'Nye': [453], 'J.A.': [454, 756, 1191, 1219, 1272, 1312, 1658, 1705, 1901, 3612], 'Graves': [455, 662, 679], 'B.J.': [456, 487, 546, 663, 680, 4396], 'Genes': [457, 757, 842, 1377, 1659, 1706, 1902, 3613], 'Dev.': [458, 758, 843, 1660, 1707, 1903, 3614], '1990;': [459], '4:': [460], '1451-1453Crossref': [461], 'PubMed': [462, 496, 528, 555, 670, 688, 717, 742, 762, 795, 818, 847, 926, 952, 989, 1017, 1044, 1084, 1158, 1224, 1277, 1383, 1405, 1467, 1531, 1564, 1591, 1664, 1711, 1907, 1980, 1996, 2131, 2290, 3593, 3618, 4416], 'Scopus': [463, 529, 671, 689, 718, 743, 763, 796, 819, 848, 927, 953, 990, 1018, 1045, 1085, 1159, 1225, 1278, 1384, 1406, 1468, 1532, 1565, 1592, 1665, 1712, 1908, 1981, 2132, 2291, 3594, 3619, 4417], '(383)': [464], 'Google': [465, 497, 531, 556, 673, 691, 720, 745, 765, 798, 821, 850, 870, 889, 909, 929, 955, 992, 1020, 1047, 1087, 1161, 1196, 1227, 1280, 1317, 1355, 1386, 1408, 1470, 1534, 1567, 1594, 1608, 1667, 1714, 1910, 1983, 1997, 2134, 2293, 3596, 3621, 4419], 'Scholar).': [466, 498, 532, 557, 746, 930, 1048, 1088, 1162, 1228, 1281, 1318, 1409, 1471, 1609, 1668, 1715, 2135, 2294, 3597], 'proteins': [468, 534, 538, 560, 606, 622, 977, 1478, 1490, 1631, 3407, 3442, 3770, 4009, 4033, 4077, 4188], 'found': [470], 'exclusively': [471], 'multicellular': [473], 'organisms': [474], 'thought': [477], 'play': [479, 4327], 'cardinal': [480], 'roles': [481], 'development': [483], 'oncogenesis': [485], '(2Graves': [486], 'Petersen': [488, 547, 660, 677, 4401], 'J.M.': [489, 548, 661, 678, 4402], 'Adv.': [490, 549], 'Cancer': [491, 550], 'Res.': [492, 551, 791, 1400, 2127, 3589], '1998;': [493, 552, 815, 949, 986, 4413], '75:': [494, 553], '1-55Crossref': [495, 554], 'Multipleets': [499], 'genes': [500, 510, 934, 960, 1325, 1474], 'have': [501, 511, 1326, 1633, 4510], 'been': [502, 512, 776, 1327, 1634, 1732], 'identified': [503], 'individual': [505], 'organisms;': [506], 'over': [507, 2432], '20': [508, 3145], 'discovered': [513], 'thus': [514], 'far': [515], '(3Laudet': [516], 'V.': [517], 'Hanni': [518], 'Stehelin': [520, 880, 903, 1033], 'D.': [521, 873, 881, 895, 904, 1002, 1023, 1034, 1069, 1143], 'Duterque-Coquillaud': [522], 'M.': [523, 731, 1032, 1362, 1449, 1520, 1576, 1973, 1986, 2124], 'Oncogene.': [524, 814, 866, 885, 905, 922, 1192, 1220, 1273, 1313, 1351, 1604], '1999;': [525], '18:': [526], '1351-1359Crossref': [527], '(114)': [530], 'DNA-binding': [537], '(reviewed': [542], 'Ref.': [544], '2Graves': [545], 'Generally,': [558], 'activate': [561], 'transcription,': [562], 'but': [563, 614, 957], 'several': [564, 2600, 3173, 3357, 3852, 4139, 4303], 'members': [565], 'repress': [572, 1788], 'process.': [574], 'achieved': [578, 3880, 3996], 'interaction': [580], 'between': [581, 1912, 2112, 2241, 3194, 3892, 4287, 4323, 4369, 4452], '∼10-base': [587], 'pair': [588], 'sequence': [589, 1053, 1095, 1104, 1119, 1133, 1970, 2001, 2048, 2083, 2189, 3683], 'element': [590], 'termed': [591, 777, 3212], 'site': [595, 1964, 2013, 2040, 2061, 2194, 2213, 2276, 3690, 3967], 'comprising': [596, 965, 1128, 3508], 'highly': [598], 'central': [600], 'core': [601, 2188], 'sequence,': [602], '5′-GGA(A/T)-3′.': [603], 'Individual': [604], 'demonstrate': [607, 1679], 'specificity': [608, 1641], 'sequences': [610, 973, 1420, 1720, 1893, 2107, 2207, 2240, 4193, 4451], 'core,': [613], 'it': [615, 4041], 'not': [617, 1731, 2313, 2759, 4005, 4030, 4036, 4391, 4422], 'uncommon': [618], 'different': [620, 939, 3181, 3460], 'bind': [624], 'same': [627, 1411, 2482, 3859, 3873, 4015, 4062], 'site.': [630], 'Structural': [631], 'reveal': [637, 3887], 'winged-helix-turn-helix': [639], 'structure': [640, 4096], 'akin': [641], 'theEscherichia': [645], 'coli': [646, 1678], 'catabolite': [647], 'HNF3/forkhead': [652], 'heat': [654], 'shock': [655], '(4Donaldson': [658], 'L.W.': [659, 676], 'McIntosh': [664, 681], 'L.P.': [665, 682], 'Biochemistry.': [666], '1994;': [667, 714, 906, 1528], '33:': [668], '13509-13516Crossref': [669], '(69)': [672], 'Scholar,': [674, 692, 721, 851, 871, 910, 993, 1021, 1197, 1356, 1387, 1535, 1568, 1595, 1984], '5Donaldson': [675], 'EMBO': [683], 'J.': [684, 945, 982, 1397, 1441, 1514, 1524, 1549, 1974, 1987, 2169, 2200, 3202], '1996;': [685, 739, 1041, 1380, 1402], '15:': [686, 924, 1222, 1275, 1381], '125-134Crossref': [687], '(135)': [690], '6Liang': [693], 'H.': [694, 916, 1008, 1075, 1149, 1366, 1395, 1451], 'Olejniczak': [695], 'E.T.': [696], 'Mao': [697], 'X.': [698, 914, 1209, 1262], 'Nettesheim': [699], 'D.G.,': [700], 'Yu,': [701], 'L.': [702, 875, 1006, 1025, 1073, 1147, 2164], 'Thompson': [703], 'C.B.': [704], 'Fesik': [705], 'S.W.': [706], 'Proc.': [707, 1554], 'Natl.': [708, 1555], 'Acad.': [709, 1556], 'Sci.': [710, 948, 985, 1557], 'U.': [711, 1558], 'S.': [712, 733, 1215, 1268, 1372, 1559], '91:': [715], '11655-11659Crossref': [716], '(58)': [719], '7Kodandapani': [722], 'R.': [723, 1036, 1512, 1582], 'Pio': [724], 'F.': [725, 780, 1010, 1027, 1077, 1151, 1374, 1389, 1516], 'Ni': [726], 'C.Z.': [727], 'Piccialli': [728], 'G.': [729, 1458, 1462, 1522, 1551], 'Ely': [736], 'K.R.': [737], 'Nature.': [738, 1463, 2286], '380:': [740], '456-460Crossref': [741], '(269)': [744], 'pea3': [748, 829], '(8Xin': [749, 1651, 1698, 1894, 3605], 'J.H.': [750, 1185, 1306, 1652, 1699, 1895, 3606], 'Cowie': [751, 1653, 1700, 1896, 3607], 'Lachance': [753, 1655, 1702, 1898, 3609], 'P.': [754, 1456, 1656, 1703, 1899, 3582, 3610], 'Hassell': [755, 1190, 1218, 1271, 1311, 1657, 1704, 1900, 3611], '1992;': [759, 844, 1464, 1661, 1708, 1904, 3615], '6:': [760, 845, 1662, 1709, 1905, 3616], '481-496Crossref': [761, 1663, 1710, 1906, 3617], '(283)': [764, 1666, 1713, 1909, 3620], 'Scholar)': [766, 822, 890, 1911, 3622], '(the': [767, 2009, 2054, 2187, 4455], 'human': [768, 1232], 'gene': [769], 'named': [771, 3189], 'ETV4': [772], 'has': [774, 1730], 'also': [775, 835, 1284, 3366], 'E1A-F)': [778], '(9Higashino': [779], 'Yoshida': [781, 1359], 'K.': [782, 786, 788, 1211, 1264, 1360, 1376], 'Fujinaga': [783, 787, 1375], 'Y.': [784, 811, 884, 902, 921, 996, 1039, 1063, 1137, 1358, 1364, 1368, 1370], 'Kamio': [785], 'Nucleic': [789, 2125, 3587], 'Acids': [790, 2126, 3588], '1993;': [792, 1193, 1314, 1561, 1588], '21:': [793], '547-553Crossref': [794], '(85)': [797], 'Scholar,10Brown': [799], 'L.A.': [800], 'Amores': [801], 'Schilling': [803], 'T.F.': [804], 'Jowett': [805], 'T.': [806, 1447, 3232], 'Baert': [807, 876, 896, 997, 1064, 1138], 'J.L.': [808, 877, 897, 998, 1065, 1139], 'de': [809, 882, 900, 919, 1037, 1454], 'Launoit': [810, 883, 901, 920, 995, 1038, 1062, 1136], 'Sharrocks': [812], 'A.D.': [813], '17:': [816, 2129, 3591], '93-104Crossref': [817], '(54)': [820], 'founding': [825], 'subfamily': [830, 834, 1058, 1324], 'ofets': [831], 'genes.': [832], 'This': [833, 2217, 2363, 2438], 'includes': [836], 'er81(ETV1)': [837], '(11Brown': [838], 'T.A.': [839], 'McKnight': [840], 'S.L.': [841, 1541, 1572, 1597], '2502-2512Crossref': [846], '(239)': [849], '12Jeon': [852], 'I.S.': [853, 942, 979, 1338], 'Davis': [854, 1339], 'J.N.': [855, 1340], 'Braun': [856, 1341, 1573, 1598], 'B.S.': [857, 1342, 1574, 1599], 'Sublett': [858, 1343], 'J.E.': [859, 1344], 'Roussel': [860, 1345, 1519], 'M.F.': [861, 1346], 'Denny': [862, 1347, 1552, 1583, 1600], 'C.T.': [863, 1187, 1308, 1348, 1553, 1584, 1601], 'Shapiro': [864, 943, 980, 1349], 'D.N.': [865, 944, 981, 1350], '1995;': [867, 886, 1352, 1605], '10:': [868, 1353, 1606], '1229-1234PubMed': [869, 1354], '13Monte': [872], 'Coutte': [874, 1005, 1024, 1072, 1146], 'Angeli': [878], 'I.': [879, 1453, 2122], '11:': [887], '771-779PubMed': [888], 'erm': [892], '(ETV5)': [893], '(14Monte': [894], 'Defossez': [898, 917, 1003, 1028, 1070, 1144], 'P.A.': [899, 918, 1004, 1029, 1071, 1145], '9:': [907], '1397-1406PubMed': [908], '15Chotteau-Lelievre': [911], 'Desbiens': [913], 'Pelczar': [915, 1007, 1074, 1148], '1997;': [923, 1014, 1081, 1155, 1221, 1274], '937-952Crossref': [925], '(132)': [928], 'Each': [931, 4437], 'located': [936, 4368, 4491], 'on': [937, 2305, 3037, 3165, 3301, 3857, 4376], 'chromosome': [940], '(16Jeon': [941, 978], 'Korean': [946, 983], 'Med.': [947, 984, 1013, 1080, 1154], '13:': [950, 987, 1589], '355-360Crossref': [951, 988], '(6)': [954, 991], 'Scholar),': [956], 'all': [958, 1231, 1959, 2003, 2300, 3806], 'three': [959, 1090, 3816], 'share': [961], 'common': [963, 1433], 'architecture': [964], '14': [966], 'equivalently': [967], 'sized': [968], 'exons': [969], 'encode': [971, 1475, 4031], 'similar': [972, 4315], 'respective': [976], '17de': [994], 'Chotteau': [999, 1066, 1140], 'Monte': [1001, 1068, 1142], 'Leenders': [1009, 1076, 1150], 'Biochem.': [1011, 1078, 1152, 1398], 'Mol.': [1012, 1079, 1153, 1525, 1585, 1975], '61:': [1015, 1082, 1156], '127-135Crossref': [1016, 1083, 1157], '(83)': [1019, 1086, 1160], '18Monte': [1022], 'Dewitte': [1026], 'Le': [1030], 'Coniat': [1031], 'Berger': [1035], 'Genomics.': [1040], '35:': [1042], '236-240Crossref': [1043], '(27)': [1046], 'overall': [1050], 'similarity': [1054, 1096], 'PEA31': [1057], '∼50%': [1060], '(17de': [1061, 1135], 'longest': [1091], 'stretches': [1092], 'greatest': [1094], 'include': [1097], '85-amino': [1099], '(95%': [1103], 'identity);': [1105, 1120], 'acidic': [1107], 'region': [1108, 1123, 1412], 'terminus': [1112, 1127, 1777, 3225, 4178], 'composed': [1113], '32': [1115], '(85%': [1118], '∼60': [1129], '(50%': [1132], 'identity)': [1134], 'overexpressed': [1165, 1285], 'breast': [1167, 1233], 'tumors': [1168, 1234, 1248, 1289], 'humans': [1171, 1336], 'mice,': [1173], 'suggesting': [1174], 'role': [1176, 4329], 'malignancy': [1181], '(19Trimble': [1182, 1303], 'M.S.': [1183, 1304], 'Xin': [1184, 1305], 'Guy': [1186, 1307], 'Muller': [1188, 1309, 3583], 'W.J.': [1189, 1310], '8:': [1194, 1315], '3037-3042PubMed': [1195, 1316], '20Benz': [1198], 'C.C.': [1199, 1252], "O'Hagan": [1200, 1253], 'R.C.': [1201, 1254], 'Richter': [1202, 1255], 'B.': [1203, 1256, 1443, 4144], 'Scott': [1204, 1257], 'G.K.': [1205, 1258], 'Chang': [1206, 1259], 'C.H.': [1207, 1260], 'Xiong': [1208, 1261], 'Chew': [1210, 1263], 'Ljung': [1212, 1265], 'B.M.': [1213, 1266], 'Edgerton': [1214, 1267], 'Thor': [1216, 1269], '1513-1525Crossref': [1223, 1276], '(155)': [1226, 1279], '76%': [1229], 'contain': [1235], 'elevated': [1236], 'levels': [1237, 2413, 3327, 3991], 'RNA;': [1240], '93%': [1241], 'c-ERB-B2/HER2-positive': [1244], 'subclass': [1245], 'overexpress': [1249], '(20Benz': [1251], 'mouse': [1287, 1504, 3256, 3278], 'mammary': [1288, 1301], 'arising': [1290], 'transgenic': [1292], 'mice': [1293], 'engineered': [1294], 'express': [1296], 'murine': [1297], 'c-Erb-B2/Her2': [1298], 'their': [1300, 1623, 2329, 3701, 3939, 4066, 4217, 4349], 'glands': [1302], 'Chromosomal': [1319], 'translocations': [1320], 'involving': [1321], 'implicated': [1328], 'minority': [1331], "Ewing's": [1333], 'sarcomas': [1334], '(12Jeon': [1337], '21Kaneko': [1357], 'Handa': [1361], 'Toyoda': [1363], 'Nishihira': [1365], 'Tanaka': [1367], 'Sasaki': [1369], 'Ishida': [1371], 'Higashino': [1373], 'Chromosomes': [1378], 'Cancer.': [1379], '115-121Crossref': [1382], '(203)': [1385], '22Urano': [1388], 'Umezawa': [1390], 'Hong': [1392], 'W.': [1393, 3586], 'Kikuchi': [1394], 'Hata': [1396], 'Biophys.': [1399], 'Commun.': [1401], '219:': [1403], '608-612Crossref': [1404], '(151)': [1407], 'EWS': [1414], 'translocated': [1416], 'juxtaposed': [1418, 3862, 3968], 'encoding': [1421, 2613, 2728, 2839, 3556, 3828], 'theFLI-1': [1426], 'gene,': [1428], 'most': [1432], 'disease': [1437], '(23Delattre': [1438], 'O.': [1439, 1518, 1547], 'Zucman': [1440, 1513, 1548], 'Plougastel': [1442], 'Desmaze': [1444], 'Melot': [1446], 'Peter': [1448], 'Kovar': [1450], 'Joubert': [1452], 'Jong': [1455], 'Rouleau': [1457], 'Aurias': [1459], 'Thomas': [1461, 1521, 1550], '359:': [1465], '162-165Crossref': [1466], '(1562)': [1469], 'EWS-FLI-1': [1472, 1476], 'chimeric': [1473, 1489, 2732, 3406], 'fusion': [1477, 2800], 'bear': [1480], 'domain.': [1483, 1824, 4502], 'transcriptional': [1485, 1615, 2323, 2394, 2582, 3434, 4047, 4183, 4381], 'significantly': [1491], 'supersedes': [1492], 'FLI-1,': [1495, 1498], 'and,': [1496], 'unlike': [1497], 'they': [1499, 2543], 'induce': [1500], 'transformation': [1501], '3T3': [1505], 'fibroblast': [1506], 'cell': [1507, 1849, 2973, 3104], 'line': [1508, 3891], '(24Bailly': [1509], 'Bosselut': [1511], 'Cormier': [1515], 'Delattre': [1517, 1546], 'Ghysdael': [1523], 'Cell.': [1526, 1586], 'Biol.': [1527, 1587, 1976, 1988, 4412], '14:': [1529], '3230-3241Crossref': [1530], '(326)': [1533], '25May': [1536], 'W.A.': [1537, 1570, 1603], 'Gishizky': [1538], 'M.L.': [1539], 'Lessnick': [1540, 1571], 'Lunsford': [1542, 1579], 'L.B.': [1543, 1580], 'Lewis': [1544, 1577], 'B.C.': [1545, 1578], '90:': [1562], '5752-5756Crossref': [1563], '(489)': [1566], '26May': [1569], 'Hromas': [1581], '7393-7398Crossref': [1590], '(447)': [1593], '27Lessnick': [1596], 'May': [1602], '423-431PubMed': [1607], 'imply': [1612], 'chimeras': [1619, 1672, 1759, 2098, 2146, 2705, 2751, 2789, 2810, 3332, 3359], 'associated': [1621], 'transforming': [1624], 'oncogenic': [1626], 'potential.': [1627], 'Like': [1628], 'other': [1629, 4304], 'studied,': [1635], 'binds': [1637], 'activates': [1643], 'reporter': [1646, 2159, 2218, 2254, 2259, 2281, 2353, 2594, 2667, 2716, 2826, 2835, 2916, 3465, 3948, 3957, 3988, 4001], 'plasmids': [1647, 2302], 'bearing': [1648, 2147, 2228, 3271, 3685], 'PEA3-responsive': [1649, 2155, 2593, 3947], 'promoters': [1650], 'glutathioneS-transferase-PEA3': [1671], 'purified': [1676, 3727], 'fromE.': [1677], 'as': [1692, 2151, 2385, 2560, 2578, 2858, 3091, 3321, 3473, 3522, 3577, 3602, 3693, 3758, 3797, 3885, 4017], 'assessed': [1693, 2332, 2707, 2753], 'vitro': [1695], 'EMSA': [1697], 'transactivation': [1723, 1828, 4515], 'investigated.': [1733], 'end': [1736, 4204], 'constructed': [1738, 1888, 2100, 3914], 'measured': [1740, 2422, 2931, 3367], 'specific': [1742, 2393, 2424, 2680, 2783, 3433, 3762, 3788, 4067, 4070, 4124, 4182, 4229, 4300], 'series': [1746, 3349], 'unidirectional': [1748, 3918], 'C-terminal': [1751, 2032, 2078, 2148, 3273, 3921, 4102, 4425, 4456, 4478], 'GAL4-PEA3': [1758, 2097, 2145, 2360, 2378, 2408, 2509, 2704, 2731, 2750, 2773, 2788, 2842, 3300, 3331, 3358, 3441], 'Our': [1764], 'negative': [1783, 4296], 'regulatory': [1784, 1818, 4297], 'regions,': [1785], 'markedly': [1787], 'DNA.': [1801, 2650], 'uncovered': [1808], 'antibodies': [1813, 3174, 3210], 'or': [1814, 2328, 2359, 2372, 2429, 2477, 2500, 2896, 2969, 3106, 3315, 3537, 3830, 4172, 4516, 4526], 'deleting': [1816], 'flank': [1821], 'Hence,': [1825, 4285], 'functions': [1832], 'controlled,': [1837], 'implying': [1838, 4190, 4320, 4449], 'mechanism(s)': [1841], 'exists': [1842], 'COS-1': [1848, 3479], 'were': [1850, 1871, 1926, 2099, 2141, 2208, 2303, 2312, 2409, 2516, 2526, 2544, 2574, 2877, 2887, 2907, 2975, 2998, 3118, 3163, 3319, 3470, 3481, 3498, 3571, 3599, 3706, 3810, 3836, 3846, 3861, 3875, 3928, 4010, 4035, 4108, 4213, 4345, 4390, 4428], 'maintained': [1851, 2623], "Dulbecco's": [1853], 'modified': [1854], "Eagle's": [1855], 'medium': [1856], 'supplemented': [1857], '10%': [1859, 3121, 4235], 'fetal': [1860], 'bovine': [1861, 3087, 3645], 'serum': [1862, 3088, 3646], 'antibiotics': [1864], '(penicillin,': [1865], 'streptomycin,': [1866], 'fungizone).': [1868], 'grown': [1872], '37': [1874], '°C': [1875, 3054], 'humidified': [1878], '5%': [1879, 3154], 'CO2': [1880], 'atmosphere.': [1881], 'expression': [1884, 2806, 3326, 3512, 3530, 3554, 3780, 3944, 3983, 4120, 4222], 'vector': [1885, 3531, 3555], '(pRSV-PEA3)': [1886], 'cloning': [1890, 1941, 2102, 2222], 'cDNA': [1892], 'Hin': [1914, 1946, 1962, 2010, 2246], 'dIII': [1915, 1963, 2011, 2247], 'andXba': [1916], 'I': [1917, 2038, 2059, 2117, 2212, 2275, 3720], 'sites': [1918, 2118, 2248, 2270], 'pRc/RSV': [1920, 3935], '(Invitrogen).': [1921], 'amino-terminal': [1923, 1956, 4164, 4203, 4258, 4307, 4336], 'derived': [1927, 2220, 3238], 'from': [1928, 2108, 2345, 2821, 2830, 2909, 2987, 3103, 3111, 3114, 3871, 3933, 3945, 3978, 3986, 4138, 4148, 4176], 'pRSV-PEA3': [1929], 'polymerase': [1931, 2024, 2103, 2316, 3719], 'chain': [1932, 2025, 2104, 2317], 'reaction': [1933, 2026, 2318, 3712], 'amplification': [1934], 'using': [1935, 2554, 2769, 2912, 2932, 3080, 3368, 3395, 3408, 3458, 3721, 3750, 3848], 'suitable': [1936], 'primers': [1937, 1951, 2006, 2027], 'followed': [1938], 'molecular': [1940, 2320], 'product': [1944], 'into': [1945, 2210, 2272, 2528], 'dIII–Xba': [1947], 'I-cleaved': [1948], 'pRc/RSV.': [1949], 'used': [1952, 2028, 2087, 2142, 2889, 3062, 3294, 3320, 3532, 3630, 3660, 3692, 3739], 'derive': [1954, 2144, 2391, 3544, 4065], 'comprised': [1960], 'translation': [1967, 2016], 'initiation': [1968, 2017], 'consensus': [1969], '5′-ACCATGG-3′': [1971], '(28Kozak': [1972], '1987;': [1977], '196:': [1978], '947-950Crossref': [1979], '(996)': [1982], '29Kozak': [1985], 'Chem.': [1989], '1991;': [1990], '266:': [1991], '19867-19870Abstract': [1992], 'Full': [1993], 'Text': [1994], 'PDF': [1995], 'Scholar);': [1998], 'invariant': [2000], '5′-GGAAGCTTACCATGG-3′': [2008], 'recognition': [2012], 'codon': [2018, 2044, 2056, 2068, 2072, 2140], 'underlined).': [2020, 2063, 2196], 'All': [2021], 'generate': [2030], 'contained': [2035, 2262, 3631], 'Xba': [2037, 2058, 2116], 'restriction': [2039], 'stop': [2043, 2055, 2071, 2139], '(5′-TAG-3′);': [2045], 'complementary': [2047, 3682], 'primer': [2051, 2086], '5′-TAGAGATCTCC-3′': [2053], 'cleavage': [2060], 'A': [2064, 3280, 3665, 3675, 4092, 4145], 'naturally': [2065], 'occurring': [2066], 'precedes': [2069], 'mRNA': [2075], 'each': [2077, 2085, 2383, 2397, 2638, 2864, 2910, 3071, 3451, 3541, 3567, 3662, 3783, 4057, 4073, 4127], 'mutant.': [2080, 3786], 'variable': [2082], 'corresponded': [2088], 'flanks': [2092], 'deletions': [2094, 4337, 4374], 'described': [2095, 2152, 2579, 2859, 3352, 3474, 3578, 3603, 3759, 4507], 'above.': [2096, 2153, 3760], 'reaction-amplified': [2105], 'RSV-PEA3': [2109], 'frame': [2111], 'theBam': [2113], 'HI': [2114], 'pSG424': [2120, 2738, 2768], '(30Sadowski': [2121], 'Ptashne': [2123], '1989;': [2128, 2287, 3590], '7539Crossref': [2130], '(472)': [2133, 2292], 'Primers': [2136], 'containing': [2137, 3153], 'unit': [2156], 'plasmid': [2160, 2255, 2260, 2354, 2452, 2595, 2611, 2668, 2717, 2838, 2961, 3513, 3937, 3949, 3958, 3981, 3989, 4002], '(PEA3': [2161], '5J.': [2162], 'Barrett,': [2163], 'MacIntosh,': [2165], 'Edwards,': [2167], 'Hassell,': [2171, 2202, 3204], 'unpublished': [2172, 3205], 'data.-luciferase)': [2173], 'five': [2175, 2263, 3960], 'copies': [2176, 2264], 'optimal,': [2179], 'high': [2180], 'affinity': [2181], 'site,': [2184], '5′-': [2185], 'TGGCCGGAACCG-3′': [2186], '2S.': [2197], 'Bowman': [2198], 'manuscript': [2203], 'preparation.': [2205], 'cloned': [2209, 2271], 'theXho': [2211], 'pGL3-Ad': [2215, 2279], 'MLP.': [2216], 'synthetic': [2224, 3953], 'double-stranded': [2225, 3677, 3724], 'oligonucleotide': [2226, 3678, 3725], '(5′-AGATCTCGAGCTCGGGGGGCTATAAAAGGGGGATCTGAATTCGAGAAGCTT-3′)': [2227], 'adenovirus': [2230], '2': [2232, 2550, 2644, 3030], 'major': [2233], 'late': [2234], 'promoter': [2235, 3954], 'TATA': [2236, 3972], 'box': [2237], 'Bgl': [2243], 'II': [2244], 'pGL3': [2251], 'basic': [2252], 'luciferase': [2253, 2336, 2352, 2459, 2489, 2805, 2818, 2882, 2905, 2933, 3943, 3985, 4051, 4221], '(Promega).': [2256], 'GAL4': [2258, 2267, 2715, 2762, 3292, 3381], '(GAL45-luciferase)': [2261], 'Sma': [2274], 'MLP': [2280], '(31Lillie': [2282], 'J.W.': [2283], 'Green': [2284], 'M.R.': [2285], '338:': [2288], '39-44Crossref': [2289], 'junctions': [2296], 'inserts': [2298], 'recombinant': [2301], 'sequenced': [2304], 'strands': [2307, 3705], 'ensure': [2309], 'mutations': [2311], 'introduced': [2314], 'during': [2315], 'cloning.': [2321], 'GAL4-PEA3,': [2327], 'derivatives': [2330, 2898, 3162], 'indirectly': [2333], 'measuring': [2335, 2814], 'equivalent': [2339], 'amounts': [2340, 2447, 2464, 2854, 3095], 'lysate': [2342, 2466, 2856, 3043], 'isolated': [2344, 4028, 4429], 'transfected': [2348, 2545, 2823, 2832, 2868, 3499], 'appropriate': [2351, 2450], 'either': [2356, 4513], 'effector': [2361, 2451, 2610, 2620, 2630, 2677, 2726, 2837, 2960, 3467, 3826, 3936, 3980], 'plasmid.': [2362, 2678], 'value': [2364, 2471], 'normalized': [2366, 4081], 'amount': [2369, 2457, 2474, 2497, 2618, 3403, 3525, 3551], 'active': [2374, 2796, 4274, 4281, 4443], 'readily': [2376, 2798], 'detected': [2377, 2799, 3164], 'chimera': [2379, 2843, 2851], '(GAL4-PEA3dlC85)': [2380], 'experiment': [2384, 2483, 3452, 3542, 4063, 4151], 'determined': [2386, 2585, 2659, 3074, 3444, 3772], 'immunoblot': [2388, 2900, 3064, 4147], 'analysis': [2389, 3421], 'protein.': [2398, 2467, 2801, 4020, 4240], 'Because': [2399, 2756], 'many': [2400, 4022], 'mutant': [2403, 4008, 4058, 4076, 4262], 'versions': [2404], 'lower': [2412], 'than': [2414, 3994, 4275, 4282, 4445], 'corresponding': [2416, 3248], '(WT)': [2419], 'proteins,': [2420], 'WT': [2427, 2614, 2694, 3528, 3793, 3975, 4019, 4085, 4137, 4239, 4283, 4447], 'GAL4-PEA3dlC85': [2431, 2478, 2501, 3362], 'range': [2434], 'concentrations.': [2437], 'accomplished': [2440, 3412], 'transfecting': [2442], 'varying': [2446], 'present': [2461, 2502], 'equal': [2463, 2853], 'Normalization': [2468], 'linear': [2486], 'increase': [2487], 'directly': [2493], 'proportional': [2494], 'lysates.': [2505], 'assayed': [2512], 'study': [2515], 'within': [2518, 3447], 'limits': [2520], 'values.': [2523], 'seeded': [2527], 'six-well': [2529, 2875], 'plates': [2530, 2989], 'density': [2533, 3490], '1.2': [2535], '×': [2536, 3493], '105': [2537, 3494], 'cells/well,': [2538], '24': [2540], 'h': [2541, 2569, 3574], 'later': [2542], 'total': [2548, 2617, 2634, 2735, 2951, 3067, 3101, 3502, 3550], 'μg': [2551, 2590, 2626, 2645, 2664, 2712, 2724, 2744, 2949, 3099, 3108, 3505, 3510, 3517, 3565, 3655], '6': [2555, 3504], 'μl': [2556, 2914, 3005], 'LipofectAMINE': [2558], 'reagent': [2559, 2935], 'specified': [2561], 'manufacturer': [2564], '(Life': [2565], 'Technologies,': [2566], 'Inc.).': [2567], '48': [2568, 3573], 'after': [2570, 2660, 2953, 3575], 'transfection,': [2571], 'harvested': [2575], 'lysed': [2577], 'below.': [2580, 2860], 'following': [2586, 2844, 3625, 3997], 'transfection': [2587, 2639, 3576, 3998], '0.5': [2589, 2663, 2723, 2743], '(PEA35-luciferase)': [2596], 'one': [2598, 3171, 3176, 3348], 'doses': [2601], '(0.2,': [2602], '0.4,': [2603], '0.6,': [2604], '0.8': [2606, 2625], 'μg)': [2607, 2674, 3539], '(pRc/RSV-PEA3)': [2612], 'PEA3.': [2615, 3279, 4284, 4334, 4522], 'adding': [2628], 'empty': [2629, 2959], '(pRc/RSV).': [2632], 'concentration': [2636, 2736, 3069], 'mixture': [2640], 'adjusted': [2642, 2741], 'sheared': [2647], 'salmon': [2648, 3519], 'sperm': [2649, 3520], 'cotransfection': [2661], 'single': [2671, 4150], 'dose': [2672], '(0.8': [2673], 'various': [2684, 2730, 2787, 3438, 3464, 3768, 4099, 4504], 'relative': [2690, 2790, 2945, 4119], 'set': [2698, 3562, 3796, 3916, 4089], '100%.': [2700, 3798, 4091], 'similarly,': [2708], 'except': [2709, 3476], '0.25': [2711], 'cotransfected': [2719], 'up': [2721], 'proteins.': [2733], 'when': [2745], 'select': [2749], 'titration.': [2755], 'encoded': [2766], 'immunoblotting,': [2770], 'because': [2772], '(bearing': [2774], 'full-length': [2775], 'PEA3)': [2776, 4459], 'transcriptionally': [2778], 'inactive,': [2779], 'GAL4-PEA3dlN85,': [2794], 'magnitude': [2803], 'effected': [2807], 'calculated': [2812, 4079], 'ratio': [2816], 'obtained': [2820, 2829], 'particular': [2841], 'normalization': [2845], 'abundance': [2848, 2893, 2966, 3298, 3355, 4055], 'Within': [2861], 'experiment,': [2863, 3449], 'preparation': [2866], 'quadruplicate;': [2870], 'wells': [2872, 2886, 2979], 'dish': [2876], 'processed': [2879], 'measure': [2881, 4045], 'activity,': [2883, 4350], 'determine': [2891, 2964], 'analysis.': [2901, 3065], 'Cell': [2902], 'extracts': [2903, 3105, 3570], 'assays': [2906], 'prepared': [2908, 3572], 'well': [2911], '200': [2913], 'lysis': [2917, 3007], 'buffer': [2918, 3008, 3629], '(Promega': [2919, 2936], 'catalog': [2920, 2937, 3309], 'no.': [2921, 2938, 3310], 'E3971)': [2922], 'according': [2923], "manufacturer's": [2926], 'instructions.': [2927], 'Luciferase': [2928, 2940], 'E1483).': [2939], 'light': [2946], 'units': [2947], 'per': [2948], 'subtracting': [2954], 'control.': [2962], 'derivatives,': [2971], 'monolayers': [2974], 'washed': [2976, 3137], 'ice-cold': [2981], 'phosphate-buffered': [2982, 2994, 3151], 'saline': [2983, 3152], 'then': [2985, 3035, 3142], 'scraped': [2986], '1': [2991, 3925, 4143, 4199], 'ml': [2992], 'saline.': [2995], 'concentrated': [2999], 'centrifugation,': [3001], 'resuspended': [3002], '50': [3004, 3012, 3632, 3637], '(1%': [3009], 'Nonidet': [3010], 'P-40,': [3011], 'mm': [3013, 3018, 3021, 3633, 3638, 3641, 3649], 'Tris-HCl,': [3014, 3634], 'pH': [3015, 3635], '7.4,': [3016, 3636], '5': [3017, 3047, 3640, 3654], 'EDTA,': [3019], '400': [3020], 'NaCl,': [3022, 3639], '10': [3023, 3026], 'μg/ml': [3024, 3027, 3031], 'leupeptin,': [3025], 'pepstatin,': [3028], 'phenylmethylsulfonyl': [3032], 'fluoride),': [3033], 'incubated': [3036], 'ice': [3038], '25': [3040], 'min.': [3041], 'centrifuged': [3045], 'min': [3048, 3146], '13,000': [3050], 'rpm': [3051], '4': [3053], 'microcentrifuge,': [3057], 'supernatant': [3060], 'sample': [3072], 'Bradford': [3077], 'dye': [3078], 'method': [3079], 'kit': [3082], 'provided': [3083], 'Bio-Rad': [3085], 'albumin': [3089], '(Sigma)': [3090], 'standard.': [3093], 'Equal': [3094], '(20': [3098], '8': [3107], 'extracts)': [3113], 'duplicate': [3116, 3446], 'samples': [3117], 'resolved': [3119], 'SDS-polyacrylamide': [3122], 'gel': [3123, 3730], 'electrophoresis': [3124], 'transferred': [3126], 'polyvinylidene': [3129], 'difluoride': [3130], 'membrane': [3131, 3135, 3167], 'electroblotting.': [3133], 'distilled': [3139], 'water': [3140], 'blocked': [3143], 'room': [3148], 'temperature': [3149], 'nonfat': [3155], 'dry': [3156], 'milk.': [3157], 'deleted': [3161, 3832], 'use': [3169, 3336], 'including': [3175], 'monoclonal': [3177, 3186], 'antibody': [3178, 3187, 3284, 3373, 3389, 3667], 'polyclonal': [3182, 3209, 3283, 3371], 'antibodies.': [3183, 3323], 'MP16': [3190], 'recognizes': [3192], 'determinants': [3193], 'residues': [3195, 4207, 4286, 4322, 4340, 4370, 4453], '226': [3196], '245.': [3198], '3L.': [3199], 'Hastings': [3200], 'results.': [3206], 'rabbit': [3208, 3282, 3370], 'PN1': [3213, 3236], 'PC2': [3215, 3259], 'recognize': [3217], 'epitopes': [3218], 'extreme': [3221], 'respectively.': [3228, 4160], '4S.': [3229], 'Arber': [3230], 'Jessell,': [3233], 'personal': [3234], 'communication.': [3235], 'injecting': [3240, 3263], 'rabbits': [3241, 3264], 'keyhole': [3244, 3267], 'limpet': [3245, 3268], 'hemocyanin-conjugated': [3246, 3269], 'peptide': [3247, 3270], 'first': [3251, 4265], '15': [3252, 3274], 'whereas': [3258, 3548], 'raised': [3261], 'commercial': [3281], 'reactive': [3285, 3374], 'quantify': [3296], 'immunoblots': [3302], '(Upstate': [3303], 'Biotechnology,': [3304], 'Inc.,': [3305, 3755], 'Lake': [3306], 'Placid,': [3307], 'NY;': [3308], '06-262).': [3311], '125I-Labeled': [3312], 'goat': [3313, 3316, 3387], 'anti-mouse': [3314], 'anti-rabbit': [3317, 3388], 'IgG': [3318], 'secondary': [3322, 3386], 'Quantification': [3324, 3400], 'performed': [3334], 'PhosphorImager': [3339, 3752], '(Molecular': [3340, 3753], 'Dynamics)': [3341], 'equipped': [3342], 'ImageQuant': [3344], '3.3': [3345], 'software.': [3346], 'In': [3347, 3851, 4039], 'experiments': [3351, 3809, 4140], 'here,': [3353], '(GAL4-PEA3dlC100,': [3360], 'GAL4-PEA3dlN42dlC100,': [3361], 'GAL4-PEA3dlN42dlC85)': [3364], 'primary': [3372], '(BAbCo;': [3382], 'PRB-255C)': [3383], 'coupled': [3390], 'peroxidase': [3392], '(KPL;': [3393], '474-1506)': [3394], 'chemiluminescence': [3396], '(PerkinElmer': [3397], 'Life': [3398], 'Sciences).': [3399], 'reagents': [3410], 'Kodak': [3415, 3418], 'ImageStation': [3416], '1D': [3419], 'image': [3420], 'software': [3422], 'version': [3423], '3.0.': [3424], 'Unless': [3425, 3799], 'indicated': [3426], 'otherwise': [3427, 3801], 'figure': [3430, 3804], 'legends,': [3431, 3805], 'repeated': [3454], 'least': [3456, 3820], 'twice': [3457], 'preparations': [3461, 3823], 'DNAs.': [3468], 'Transfections': [3469], 'carried': [3471, 3600, 3811], 'out': [3472, 3601, 3812], 'above': [3475], 'initially': [3482], 'plated': [3483], '60-mm': [3485], '(diameter)': [3486], 'dishes': [3487], '∼3': [3492], 'cells/dish.': [3495], 'carrier.': [3523], 'varied': [3534], '(1,': [3535], '2,': [3536], 'normal': [3546], 'curve,': [3547], 'experiment.': [3568], 'Nuclear': [3569], '(32Schreiber': [3579], 'E.': [3580], 'Matthias': [3581], 'M.M.': [3584], 'Schaffner': [3585], '6419Crossref': [3592], '(3918)': [3595], 'EMSAs': [3598], 'previously': [3604, 4508], 'modifications.': [3626], 'dithiothreitol,': [3642], '0.2': [3643], 'mg/ml': [3644], 'albumin,': [3647], '0.4': [3648], 'spermidine,': [3650], '7%': [3652], 'glycerol.': [3653], 'extract': [3658], 'reaction.': [3664], 'added': [3669], 'reactions': [3672], 'where': [3673], 'stated.': [3674], 'radiolabeled': [3676], '(5′-AATTCGCGAGTGGCCGGAACCGGACG-3': [3679], '5′-GATCCGTCCGGTTCCGGCCACTCGCG-3′)': [3684], 'optimal': [3687, 3964], 'probe': [3695], 'assays.2': [3698], 'Prior': [3699], 'use,': [3702], 'annealed': [3707], 'labeled': [3709], 'fill-in': [3711], 'Klenow': [3715], 'fragment': [3716], '[α-32P]dATP.': [3722], 'polyacrylamide': [3729], 'electrophoresis,': [3731], '0.3': [3733], 'ng': [3734], 'assays.': [3743], 'quantified': [3748], 'Dynamics,': [3754], 'Sunnyvale,': [3756], 'CA)': [3757], 'PEA3-related': [3769], 'normalizing': [3774], 'level': [3781, 4016, 4121], 'stated': [3800], 'minimum': [3814], 'times': [3817], 'independent': [3822], 'DNAs': [3827], 'derivatives.': [3833], 'Original': [3834], 'autoradiographs': [3835], 'scanned': [3837], 'Adobe': [3839], 'Photoshop': [3840], '3.0,': [3841], 'final': [3844, 3897], 'figures': [3845, 3898], 'produced': [3847], 'Canvas': [3849], '5.': [3850], 'figures,': [3855], 'lanes': [3856, 3870], 'autoradiogram': [3860, 3874], 'facilitate': [3864], 'representation': [3865], 'data.': [3868], 'When': [3869], 'spaced': [3876], 'together,': [3877, 4467], 'such': [3882], 'way': [3884], 'thin': [3889], 'white': [3890], 'adjacent': [3893], 'lanes.': [3894], 'Otherwise,': [3895], 'faithful': [3900], 'representations': [3901], 'original': [3904], 'autoradiograms.': [3905], 'define': [3907], '(Fig.': [3924, 4198], 'A).': [3926], 'capacity': [3940, 4218], 'stimulate': [3942, 4220], 'measured.': [3951], 'repeats': [3961], 'minimal': [3971], 'box.': [3973], 'Commonly,': [3974], 'increased': [3982, 4180, 4525], '10–20-fold': [3992], 'higher': [3993], 'alone': [4003], '(data': [4004], 'shown).': [4006, 4423], 'rarely': [4011], 'Indeed,': [4021, 4227], 'did': [4029], 'stable': [4032], 'analyzed': [4037, 4109], 'further.': [4038], 'consequence,': [4040], 'necessary': [4043], '(represented': [4049], 'activity)': [4052], 'schematic': [4093], 'illustrated': [4111], 'Fig.1': [4113], 'We': [4115], 'report': [4116], 'average': [4118], 'comparison': [4133, 4224], 'Fig.': [4142, 4155], 'representative': [4146], 'shown': [4153], 'C': [4157], 'D,': [4159], 'truncation': [4165], '29': [4171], '45': [4173], 'reproducibly': [4179, 4441], 'resulting': [4187], '2–3-fold,': [4189], 'B).': [4200], 'Mutants': [4201], 'points': [4205], '55,': [4208], '65,': [4209], '74,': [4210], '85': [4212, 4290], 'progressively': [4214, 4305], 'compromised': [4215], 'WT.': [4226], 'dlN85': [4232, 4276], 'only': [4234, 4278], 'observations': [4242], 'consistent': [4244, 4351], 'presence': [4247], 'positively': [4249, 4486], 'acting': [4250, 4489], 'sequences,': [4251], 'perhaps': [4252], 'domain,': [4255], 'region.': [4259, 4298, 4361], 'Surprisingly,': [4260], 'lacking': [4263], '106': [4266, 4292, 4324], '5-fold': [4272], 'more': [4273, 4442], '2-fold': [4279], 'less': [4280], 'may': [4293, 4509], 'comprise': [4294], 'another': [4295, 4356], 'larger': [4306], '(dlN120,': [4310], 'dlN130,': [4311], 'dlN145)': [4313], 'dl106,': [4319], '145': [4326], 'extending': [4338], '226,': [4341], '245,': [4342], '326': [4344], 'increasingly': [4346], 'reduced': [4347], 'occurrence': [4354, 4483], '334': [4371], '417;': [4373], 'impinging': [4375], 'abolished': [4380], 'probably': [4383], 'compromising': [4385], 'consequently': [4389], 'characterized': [4392, 4431], 'further': [4393], '(Ref.': [4394], '41Graves': [4395], 'Cowley': [4397], 'D.O.': [4398], 'Goetz': [4399], 'T.L.': [4400], 'Jonsen': [4403], 'M.D.': [4404], 'Gillespie': [4405], 'M.E.': [4406], 'Cold': [4407], 'Spring': [4408], 'Harb.': [4409], 'Symp.': [4410], 'Quant.': [4411], '63:': [4414], '621-629Crossref': [4415], '(31)': [4418], 'Scholar;': [4420], 'data': [4421], 'Four': [4424], '(dlC450,': [4432], 'dlC440,': [4433], 'dlC430,': [4434], 'dlC420).': [4436], '(∼2-fold)': [4444], 'protein,': [4448], 'residue': [4457], '450': [4461], 'Taken': [4466], 'results': [4469], 'amino-': [4476], 'suggested': [4481], 'outside': [4492], 'borders': [4495], 'lesions': [4511], 'affecting': [4512], 'function': [4520], 'Deletions': [4523], 'decreased': [4527], 'PEA': [4528]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2076111240', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-04T17:18:33.424311', 'created_date': '2016-06-24'}