Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2076064699', 'doi': 'https://doi.org/10.1159/000026376', 'title': 'Autonomic Innervation of Human Airways: Structure, Function, and Pathophysiology in Asthma', 'display_name': 'Autonomic Innervation of Human Airways: Structure, Function, and Pathophysiology in Asthma', 'publication_year': 1999, 'publication_date': '1999-01-01', 'ids': {'openalex': 'https://openalex.org/W2076064699', 'doi': 'https://doi.org/10.1159/000026376', 'mag': '2076064699', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10213912'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000026376', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134841769', 'display_name': 'NeuroImmunoModulation', 'issn_l': '1021-7401', 'issn': ['1021-7401', '1423-0216'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027341200', 'display_name': 'Vincent H. J. van der Velden', 'orcid': 'https://orcid.org/0000-0001-9457-3763'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Vincent H.J. van der Velden', 'raw_affiliation_strings': ['Immunology and', 'Pulmonary Medicine, Erasmus University and University Hospital Dijkzigt and'], 'affiliations': [{'raw_affiliation_string': 'Immunology and', 'institution_ids': []}, {'raw_affiliation_string': 'Pulmonary Medicine, Erasmus University and University Hospital Dijkzigt and', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025276335', 'display_name': 'A. R. HULSMANN', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210142620', 'display_name': 'Erasmus MC - Sophia Children’s Hospital', 'ror': 'https://ror.org/047afsm11', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801952686', 'https://openalex.org/I4210142620']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Anthon R. Hulsmann', 'raw_affiliation_strings': ["Department of Pediatrics, Sophia Children's Hospital, Rotterdam, The Netherlands"], 'affiliations': [{'raw_affiliation_string': "Department of Pediatrics, Sophia Children's Hospital, Rotterdam, The Netherlands", 'institution_ids': ['https://openalex.org/I4210142620']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.962, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 153, 'citation_normalized_percentile': {'value': 0.997337, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '6', 'issue': '3', 'first_page': '145', 'last_page': '159'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11541', 'display_name': 'Neuroendocrine regulation and behavior', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/3207', 'display_name': 'Social Psychology'}, 'field': {'id': 'https://openalex.org/fields/32', 'display_name': 'Psychology'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780769369', 'wikidata': 'https://www.wikidata.org/wiki/Q4375', 'display_name': 'Bronchoconstriction', 'level': 3, 'score': 0.7746602}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.679562}, {'id': 'https://openalex.org/C22885893', 'wikidata': 'https://www.wikidata.org/wiki/Q4862743', 'display_name': 'Cholinergic', 'level': 2, 'score': 0.6326905}, {'id': 'https://openalex.org/C2777372248', 'wikidata': 'https://www.wikidata.org/wiki/Q171064', 'display_name': 'Autonomic nervous system', 'level': 4, 'score': 0.4390708}, {'id': 'https://openalex.org/C8330315', 'wikidata': 'https://www.wikidata.org/wiki/Q414964', 'display_name': 'Vasoactive intestinal peptide', 'level': 4, 'score': 0.41098368}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3615391}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3263115}, {'id': 'https://openalex.org/C2776042228', 'wikidata': 'https://www.wikidata.org/wiki/Q35869', 'display_name': 'Asthma', 'level': 2, 'score': 0.28941604}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.24403018}, {'id': 'https://openalex.org/C118303440', 'wikidata': 'https://www.wikidata.org/wiki/Q419968', 'display_name': 'Neuropeptide', 'level': 3, 'score': 0.1470694}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.06470254}, {'id': 'https://openalex.org/C2777953023', 'wikidata': 'https://www.wikidata.org/wiki/Q1073121', 'display_name': 'Heart rate', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D001341', 'descriptor_name': 'Autonomic Nervous System', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': True}, {'descriptor_ui': 'D012137', 'descriptor_name': 'Respiratory System', 'qualifier_ui': 'Q000294', 'qualifier_name': 'innervation', 'is_major_topic': True}, {'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000109', 'descriptor_name': 'Acetylcholine', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D000344', 'descriptor_name': 'Afferent Pathways', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001341', 'descriptor_name': 'Autonomic Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001341', 'descriptor_name': 'Autonomic Nervous System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D016084', 'descriptor_name': 'Bronchoconstriction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016084', 'descriptor_name': 'Bronchoconstriction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002799', 'descriptor_name': 'Cholinergic Fibers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002799', 'descriptor_name': 'Cholinergic Fibers', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004525', 'descriptor_name': 'Efferent Pathways', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007962', 'descriptor_name': 'Leukocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007962', 'descriptor_name': 'Leukocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007962', 'descriptor_name': 'Leukocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009411', 'descriptor_name': 'Nerve Endings', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009411', 'descriptor_name': 'Nerve Endings', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009479', 'descriptor_name': 'Neuropeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009479', 'descriptor_name': 'Neuropeptides', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D010275', 'descriptor_name': 'Parasympathetic Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010275', 'descriptor_name': 'Parasympathetic Nervous System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D010275', 'descriptor_name': 'Parasympathetic Nervous System', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D012137', 'descriptor_name': 'Respiratory System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012137', 'descriptor_name': 'Respiratory System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D013564', 'descriptor_name': 'Sympathetic Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013564', 'descriptor_name': 'Sympathetic Nervous System', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D013564', 'descriptor_name': 'Sympathetic Nervous System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D015320', 'descriptor_name': 'Tachykinins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015320', 'descriptor_name': 'Tachykinins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000026376', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134841769', 'display_name': 'NeuroImmunoModulation', 'issn_l': '1021-7401', 'issn': ['1021-7401', '1423-0216'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10213912', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.81}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 265, 'referenced_works': ['https://openalex.org/W114177200', 'https://openalex.org/W1490435256', 'https://openalex.org/W1510209565', 'https://openalex.org/W1512291126', 'https://openalex.org/W1532247415', 'https://openalex.org/W1540036539', 'https://openalex.org/W154829778', 'https://openalex.org/W1549362496', 'https://openalex.org/W1549527284', 'https://openalex.org/W1549585090', 'https://openalex.org/W155625354', 'https://openalex.org/W1567957283', 'https://openalex.org/W1573321446', 'https://openalex.org/W157512792', 'https://openalex.org/W1590629056', 'https://openalex.org/W15985', 'https://openalex.org/W163115995', 'https://openalex.org/W1732449795', 'https://openalex.org/W1751541220', 'https://openalex.org/W1764275799', 'https://openalex.org/W1769215519', 'https://openalex.org/W1771649680', 'https://openalex.org/W180641527', 'https://openalex.org/W1808476113', 'https://openalex.org/W1833471367', 'https://openalex.org/W1851098361', 'https://openalex.org/W1855852462', 'https://openalex.org/W1858902505', 'https://openalex.org/W1876102834', 'https://openalex.org/W1898901632', 'https://openalex.org/W1909518616', 'https://openalex.org/W1913692075', 'https://openalex.org/W1926261626', 'https://openalex.org/W1934561697', 'https://openalex.org/W1962105746', 'https://openalex.org/W1964065006', 'https://openalex.org/W1964195214', 'https://openalex.org/W1964982557', 'https://openalex.org/W1966329609', 'https://openalex.org/W1967825527', 'https://openalex.org/W1969531702', 'https://openalex.org/W1969623737', 'https://openalex.org/W1969997749', 'https://openalex.org/W1971469729', 'https://openalex.org/W1971866218', 'https://openalex.org/W1973411653', 'https://openalex.org/W1973631654', 'https://openalex.org/W1975474439', 'https://openalex.org/W1976700309', 'https://openalex.org/W1976884294', 'https://openalex.org/W1976980034', 'https://openalex.org/W1976988448', 'https://openalex.org/W1980462938', 'https://openalex.org/W1980599937', 'https://openalex.org/W1981578013', 'https://openalex.org/W1982844086', 'https://openalex.org/W1982861623', 'https://openalex.org/W1983064226', 'https://openalex.org/W1983116880', 'https://openalex.org/W1983179296', 'https://openalex.org/W1983410598', 'https://openalex.org/W1984632338', 'https://openalex.org/W1984952179', 'https://openalex.org/W1985764075', 'https://openalex.org/W1986885682', 'https://openalex.org/W1986944465', 'https://openalex.org/W1987793140', 'https://openalex.org/W1989103258', 'https://openalex.org/W1989584865', 'https://openalex.org/W1989711502', 'https://openalex.org/W1990052926', 'https://openalex.org/W1990279170', 'https://openalex.org/W1990673708', 'https://openalex.org/W1990754610', 'https://openalex.org/W1991751374', 'https://openalex.org/W1993790465', 'https://openalex.org/W1994106070', 'https://openalex.org/W1994786147', 'https://openalex.org/W1995688653', 'https://openalex.org/W1996023104', 'https://openalex.org/W1996972993', 'https://openalex.org/W1998259730', 'https://openalex.org/W1999115737', 'https://openalex.org/W1999962212', 'https://openalex.org/W2000228412', 'https://openalex.org/W2002833810', 'https://openalex.org/W2002896923', 'https://openalex.org/W2003284232', 'https://openalex.org/W2003763178', 'https://openalex.org/W2004096557', 'https://openalex.org/W2004508515', 'https://openalex.org/W2005092586', 'https://openalex.org/W2005999864', 'https://openalex.org/W2007315628', 'https://openalex.org/W2007587185', 'https://openalex.org/W2007678048', 'https://openalex.org/W2008092150', 'https://openalex.org/W2008125235', 'https://openalex.org/W2010095551', 'https://openalex.org/W2010215031', 'https://openalex.org/W2011521821', 'https://openalex.org/W2011993336', 'https://openalex.org/W2012452043', 'https://openalex.org/W2012469825', 'https://openalex.org/W2012747578', 'https://openalex.org/W2013135365', 'https://openalex.org/W2013376105', 'https://openalex.org/W2013512385', 'https://openalex.org/W2014191280', 'https://openalex.org/W2014592293', 'https://openalex.org/W2016919586', 'https://openalex.org/W2017772136', 'https://openalex.org/W2017987081', 'https://openalex.org/W2019562281', 'https://openalex.org/W2020381435', 'https://openalex.org/W2023838287', 'https://openalex.org/W2025136776', 'https://openalex.org/W2025249559', 'https://openalex.org/W2026313282', 'https://openalex.org/W2028509749', 'https://openalex.org/W2029427410', 'https://openalex.org/W2029970130', 'https://openalex.org/W2031376908', 'https://openalex.org/W2032194488', 'https://openalex.org/W2033827368', 'https://openalex.org/W2034850914', 'https://openalex.org/W2035651901', 'https://openalex.org/W2036176661', 'https://openalex.org/W2037537269', 'https://openalex.org/W2037922553', 'https://openalex.org/W2038857990', 'https://openalex.org/W2044019207', 'https://openalex.org/W2045166690', 'https://openalex.org/W2045181044', 'https://openalex.org/W2046421752', 'https://openalex.org/W2046470493', 'https://openalex.org/W2046511246', 'https://openalex.org/W2046745460', 'https://openalex.org/W2046819503', 'https://openalex.org/W2047920764', 'https://openalex.org/W2048556307', 'https://openalex.org/W2049079234', 'https://openalex.org/W2049100363', 'https://openalex.org/W2049151832', 'https://openalex.org/W2049452083', 'https://openalex.org/W2050299716', 'https://openalex.org/W2050399061', 'https://openalex.org/W2050657361', 'https://openalex.org/W2051159483', 'https://openalex.org/W2051231769', 'https://openalex.org/W2052129627', 'https://openalex.org/W2053188329', 'https://openalex.org/W2053277833', 'https://openalex.org/W2054510493', 'https://openalex.org/W2054619820', 'https://openalex.org/W2055020310', 'https://openalex.org/W2057856846', 'https://openalex.org/W2060613120', 'https://openalex.org/W2061435327', 'https://openalex.org/W2062511576', 'https://openalex.org/W2062976044', 'https://openalex.org/W2063386085', 'https://openalex.org/W2063721865', 'https://openalex.org/W2064566965', 'https://openalex.org/W2066684203', 'https://openalex.org/W2068155648', 'https://openalex.org/W2069527368', 'https://openalex.org/W2070182323', 'https://openalex.org/W2070336277', 'https://openalex.org/W2071101811', 'https://openalex.org/W2071518951', 'https://openalex.org/W2071958473', 'https://openalex.org/W2073227520', 'https://openalex.org/W2073645604', 'https://openalex.org/W2074757393', 'https://openalex.org/W2076350174', 'https://openalex.org/W2076400732', 'https://openalex.org/W2077488679', 'https://openalex.org/W2079342899', 'https://openalex.org/W2080761218', 'https://openalex.org/W2081538565', 'https://openalex.org/W2082988057', 'https://openalex.org/W2084172070', 'https://openalex.org/W2084692307', 'https://openalex.org/W2087354425', 'https://openalex.org/W2090501692', 'https://openalex.org/W2091029466', 'https://openalex.org/W2092239035', 'https://openalex.org/W2092445182', 'https://openalex.org/W2094125657', 'https://openalex.org/W2094273210', 'https://openalex.org/W2094645396', 'https://openalex.org/W2094750137', 'https://openalex.org/W2095000642', 'https://openalex.org/W2097280358', 'https://openalex.org/W2101805877', 'https://openalex.org/W2107573564', 'https://openalex.org/W2108088417', 'https://openalex.org/W2109507715', 'https://openalex.org/W2110521158', 'https://openalex.org/W2110763080', 'https://openalex.org/W2113169680', 'https://openalex.org/W2116483666', 'https://openalex.org/W2117821842', 'https://openalex.org/W2124636171', 'https://openalex.org/W2129727946', 'https://openalex.org/W2131658165', 'https://openalex.org/W2132965078', 'https://openalex.org/W2137102246', 'https://openalex.org/W2139651426', 'https://openalex.org/W2141100025', 'https://openalex.org/W2148484236', 'https://openalex.org/W2150336758', 'https://openalex.org/W2155514562', 'https://openalex.org/W2157226274', 'https://openalex.org/W2157491542', 'https://openalex.org/W2159168400', 'https://openalex.org/W2171082263', 'https://openalex.org/W2171733019', 'https://openalex.org/W2177179756', 'https://openalex.org/W2181658360', 'https://openalex.org/W2186431264', 'https://openalex.org/W2186810890', 'https://openalex.org/W2186825337', 'https://openalex.org/W2189668998', 'https://openalex.org/W2192541481', 'https://openalex.org/W2227833839', 'https://openalex.org/W2229011399', 'https://openalex.org/W2230313136', 'https://openalex.org/W2230841554', 'https://openalex.org/W2233026924', 'https://openalex.org/W2251178293', 'https://openalex.org/W2254170473', 'https://openalex.org/W2254606917', 'https://openalex.org/W2257252244', 'https://openalex.org/W2270229030', 'https://openalex.org/W2281647012', 'https://openalex.org/W2300382531', 'https://openalex.org/W2304734417', 'https://openalex.org/W2346872788', 'https://openalex.org/W2395784085', 'https://openalex.org/W2399318827', 'https://openalex.org/W2403581030', 'https://openalex.org/W2414485865', 'https://openalex.org/W2414623081', 'https://openalex.org/W2415238087', 'https://openalex.org/W2416943724', 'https://openalex.org/W2417749757', 'https://openalex.org/W2418792944', 'https://openalex.org/W2419010209', 'https://openalex.org/W2421819660', 'https://openalex.org/W2430741210', 'https://openalex.org/W2438738702', 'https://openalex.org/W2440986721', 'https://openalex.org/W2441669000', 'https://openalex.org/W2444512265', 'https://openalex.org/W2472072950', 'https://openalex.org/W2474640588', 'https://openalex.org/W2774336139', 'https://openalex.org/W304077197', 'https://openalex.org/W38947021', 'https://openalex.org/W64373523', 'https://openalex.org/W66536903', 'https://openalex.org/W68034217', 'https://openalex.org/W78926374'], 'related_works': ['https://openalex.org/W4251761214', 'https://openalex.org/W3136034373', 'https://openalex.org/W2979539656', 'https://openalex.org/W2748952813', 'https://openalex.org/W2518828382', 'https://openalex.org/W2470923499', 'https://openalex.org/W2415937393', 'https://openalex.org/W2164869079', 'https://openalex.org/W2107539526', 'https://openalex.org/W1502905212'], 'abstract_inverted_index': {'The': [0, 64, 152, 293], 'human': [1, 55, 127, 141, 188, 231], 'airways': [2, 27, 56], 'are': [3, 62, 137], 'innervated': [4], 'via': [5], 'efferent': [6], 'and': [7, 34, 43, 57, 89, 145, 160, 177, 215, 248, 267, 276, 291, 302], 'afferent': [8], 'autonomic': [9, 51], 'nerves,': [10, 172, 220], 'which': [11], 'regulate': [12], 'many': [13], 'aspects': [14], 'of': [15, 25, 45, 53, 76, 82, 94, 126, 147, 155, 193, 237, 278, 296], 'airway': [16, 77, 128, 142], 'function.': [17, 292], 'It': [18], 'has': [19, 131, 197], 'been': [20, 99, 132, 198, 211, 228], 'suggested': [21, 100], 'that': [22, 35], 'neural': [23, 184], 'control': [24, 75, 119], 'the': [26, 41, 50, 54, 69, 74, 95, 105, 182, 262, 273, 281, 288, 297, 306], 'may': [28, 38, 118, 180, 271, 286], 'be': [29, 181, 314], 'abnormal': [30], 'in': [31, 60, 73, 101, 110, 165, 187, 200, 206, 223, 230, 309], 'asthmatic': [32, 111, 166], 'patients,': [33], 'neurogenic': [36], 'mechanisms': [37], 'contribute': [39], 'to': [40, 313], 'pathogenesis': [42], 'pathophysiology': [44], 'asthma.': [46], 'In': [47, 233], 'this': [48], 'review,': [49], 'innervation': [52, 97, 125], 'possible': [58], 'abnormalities': [59, 93], 'asthma': [61, 310], 'discussed.': [63], 'parasympathetic': [65], 'nervous': [66, 265, 300], 'system': [67, 266, 301, 308], 'is': [68, 113, 158], 'dominant': [70], 'neuronal': [71, 289], 'pathway': [72], 'smooth': [78, 129, 143], 'muscle': [79, 130, 144], 'tone.': [80], 'Stimulation': [81], 'cholinergic': [83, 96, 108], 'nerves': [84, 117, 196, 240], 'causes': [85, 150, 241], 'bronchoconstriction,': [86, 242], 'mucus': [87, 243], 'secretion,': [88, 244], 'bronchial': [90], 'vasodilation.': [91], 'Although': [92, 190], 'have': [98, 210, 226, 257], 'asthma,': [102, 201], 'thus': [103, 202], 'far': [104, 203], 'evidence': [106], 'for': [107], 'dysfunction': [109, 192], 'subjects': [112], 'not': [114], 'convincing.': [115], 'Sympathetic': [116], 'tracheobronchial': [120], 'blood': [121], 'vessels,': [122], 'but': [123], 'no': [124, 204], 'demonstrated.': [133], 'β-Adrenergic': [134], 'receptors,': [135], 'however,': [136], 'abundantly': [138], 'expressed': [139], 'on': [140], 'activation': [146, 277], 'these': [148], 'receptors': [149, 157], 'bronchodilation.': [151], 'physiological': [153], 'role': [154], 'β-adrenergic': [156], 'unclear': [159], 'their': [161], 'function': [162], 'seems': [163], 'normal': [164], 'patients.': [167], 'Inhibitory': [168], 'nonadrenergic': [169], 'noncholinergic': [170], '(NANC)': [171], 'containing': [173], 'vasoactive': [174], 'intestinal': [175], 'peptide': [176], 'nitric': [178], 'oxide,': [179], 'only': [183], 'bronchodilator': [185], 'pathways': [186], 'airways.': [189, 232], 'a': [191, 250], 'inhibitory': [194, 207], 'NANC': [195, 208, 219, 239, 264, 299], 'proposed': [199], 'differences': [205], 'responses': [209], 'found': [212], 'between': [213, 261], 'asthmatics': [214], 'healthy': [216], 'subjects.': [217], 'Excitatory': [218], 'extensively': [221], 'studied': [222], 'animal': [224, 234], 'airways,': [225], 'also': [227], 'detected': [229], 'studies,': [235], 'stimulation': [236], 'excitatory': [238, 263, 298], 'vascular': [245], 'hyperpermeability,': [246], 'cough,': [247], 'vasodilation,': [249], 'process': [251], 'called': [252], '‘neurogenic': [253], 'inflammation’.': [254], 'Recent': [255], 'studies': [256], 'demonstrated': [258], 'an': [259], 'interaction': [260, 304], 'inflammatory': [268, 284], 'cells.': [269], 'Neuropeptides': [270], 'influence': [272], 'recruitment,': [274], 'proliferation,': [275], 'leukocytes.': [279], 'On': [280], 'other': [282], 'hand,': [283], 'cells': [285], 'modulate': [287], 'phenotype': [290], 'functional': [294], 'relevance': [295], 'its': [303], 'with': [305], 'immune': [307], 'still': [311], 'remains': [312], 'elucidated.': [315]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2076064699', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2025-01-08T23:15:35.367421', 'created_date': '2016-06-24'}