Abstract: The entry of West Nile virus into the brain, where it can cause lethal encephalitis, is mediated by the Toll-like receptor 3 (TLR3), report Erol Fikrig (Yale University School of Medicine, New Haven, CT, USA) and colleagues. In mice, the researchers have discovered that West Nile virus infection causes a Tlr3-dependent inflammatory response that induces the reversible breakdown of the blood–brain barrier (Nat Med; published online November 11, 2004; DOI: 10.1038/nm1140).
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 1
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