Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2074167455', 'doi': 'https://doi.org/10.1038/sj.bjc.6690300', 'title': 'Second malignant neoplasms after a first cancer in childhood: temporal pattern of risk according to type of treatment', 'display_name': 'Second malignant neoplasms after a first cancer in childhood: temporal pattern of risk according to type of treatment', 'publication_year': 1999, 'publication_date': '1999-03-12', 'ids': {'openalex': 'https://openalex.org/W2074167455', 'doi': 'https://doi.org/10.1038/sj.bjc.6690300', 'mag': '2074167455', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10206309', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2362818'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/sj.bjc.6690300', 'pdf_url': 'https://www.nature.com/articles/6690300.pdf', 'source': {'id': 'https://openalex.org/S62966998', 'display_name': 'British Journal of Cancer', 'issn_l': '0007-0920', 'issn': ['0007-0920', '1532-1827'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.nature.com/articles/6690300.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037551185', 'display_name': 'Florent de Vathaire', 'orcid': 'https://orcid.org/0000-0002-8374-9281'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'F de Vathaire', 'raw_affiliation_strings': ['Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055079124', 'display_name': 'Mike Hawkins', 'orcid': 'https://orcid.org/0000-0001-6496-4800'}, 'institutions': [], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'M Hawkins', 'raw_affiliation_strings': ['Childhood Cancer Research Group, Radcliffe Infirmary, Oxford, UK'], 'affiliations': [{'raw_affiliation_string': 'Childhood Cancer Research Group, Radcliffe Infirmary, Oxford, UK', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101552987', 'display_name': 'Sarah Campbell', 'orcid': 'https://orcid.org/0000-0002-0041-1753'}, 'institutions': [{'id': 'https://openalex.org/I4210087233', 'display_name': 'Blood Cancer UK', 'ror': 'https://ror.org/0055acf80', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210087233']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'S Campbell', 'raw_affiliation_strings': ['Thames Cancer Registry, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Thames Cancer Registry, London, UK', 'institution_ids': ['https://openalex.org/I4210087233']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067218613', 'display_name': 'Odile Oberlin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'O Oberlin', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090093605', 'display_name': 'Marie‐Anne Raquin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'M-A Raquin', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072184282', 'display_name': 'J-Y Schlienger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154553', 'display_name': 'Institut Jean Godinot', 'ror': 'https://ror.org/05qjz5228', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154553']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J-Y Schlienger', 'raw_affiliation_strings': ['Institut Jean Godinot, Reims, France'], 'affiliations': [{'raw_affiliation_string': 'Institut Jean Godinot, Reims, France', 'institution_ids': ['https://openalex.org/I4210154553']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048320553', 'display_name': 'Akhtar Shamsaldin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'A Shamsaldin', 'raw_affiliation_strings': ['Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019130778', 'display_name': 'I. Diallo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'I Diallo', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077549528', 'display_name': 'Janine Bell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087233', 'display_name': 'Blood Cancer UK', 'ror': 'https://ror.org/0055acf80', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210087233']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'J Bell', 'raw_affiliation_strings': ['Thames Cancer Registry, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Thames Cancer Registry, London, UK', 'institution_ids': ['https://openalex.org/I4210087233']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045566824', 'display_name': 'E Grimaud', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'E Grimaud', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001659927', 'display_name': 'C Hardiman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'C Hardiman', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102075967', 'display_name': 'J-L Lagrange', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151846', 'display_name': 'Centre Antoine Lacassagne', 'ror': 'https://ror.org/05hmfw828', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210151846']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J-L Lagrange', 'raw_affiliation_strings': ['Centre Antoine Lacassagn, Nice, France'], 'affiliations': [{'raw_affiliation_string': 'Centre Antoine Lacassagn, Nice, France', 'institution_ids': ['https://openalex.org/I4210151846']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018267264', 'display_name': 'Nicolas Daly‐Schveitzer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210128666', 'display_name': 'Institut Claudius Regaud', 'ror': 'https://ror.org/03pa87f90', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128666']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'N Daly-Schveitzer', 'raw_affiliation_strings': ['Centre Clsaudius Regaud, Toulouse, France'], 'affiliations': [{'raw_affiliation_string': 'Centre Clsaudius Regaud, Toulouse, France', 'institution_ids': ['https://openalex.org/I4210128666']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027950718', 'display_name': 'X Panis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210154553', 'display_name': 'Institut Jean Godinot', 'ror': 'https://ror.org/05qjz5228', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I4210154553']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'X Panis', 'raw_affiliation_strings': ['Institut Jean Godinot, Reims, France'], 'affiliations': [{'raw_affiliation_string': 'Institut Jean Godinot, Reims, France', 'institution_ids': ['https://openalex.org/I4210154553']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061626775', 'display_name': 'Jean‐Michel Zucker', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I80043', 'display_name': 'Institut Curie', 'ror': 'https://ror.org/04t0gwh46', 'country_code': 'FR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I80043']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J-M Zucker', 'raw_affiliation_strings': ['Institut Curie, Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Institut Curie, Paris, France', 'institution_ids': ['https://openalex.org/I80043']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075752398', 'display_name': 'H Sancho-Garnier', 'orcid': 'https://orcid.org/0000-0002-3727-9418'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'H Sancho-Garnier', 'raw_affiliation_strings': ['Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Research Unit of Cancer Epidemiology (U351 INSERM), Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075496285', 'display_name': 'F Eschwège', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'F Eschwège', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039597422', 'display_name': 'J. Chavaudra', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J Chavaudra', 'raw_affiliation_strings': ['Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5062827900', 'display_name': 'J Lemerle', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J Lemerle', 'raw_affiliation_strings': ['Department of Pediatrics, Institut Gustave Roussy, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatrics, Institut Gustave Roussy, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3790, 'currency': 'EUR', 'value_usd': 4690, 'provenance': 'doaj'}, 'apc_paid': {'value': 3790, 'currency': 'EUR', 'value_usd': 4690, 'provenance': 'doaj'}, 'fwci': 5.899, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 148, 'citation_normalized_percentile': {'value': 0.967254, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '79', 'issue': '11-12', 'first_page': '1884', 'last_page': '1893'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11141', 'display_name': 'Pediatric Cancer and Quality of Life', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11141', 'display_name': 'Pediatric Cancer and Quality of Life', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10950', 'display_name': 'Epidemiology and Treatment of Childhood Leukemia', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10129', 'display_name': 'Gliomas', 'score': 0.9889, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/absolute-risk-reduction', 'display_name': 'Absolute risk reduction', 'score': 0.7140726}, {'id': 'https://openalex.org/keywords/childhood-cancer-survivor-study', 'display_name': 'Childhood Cancer Survivor Study', 'score': 0.575609}, {'id': 'https://openalex.org/keywords/childhood-cancer', 'display_name': 'Childhood Cancer', 'score': 0.539647}, {'id': 'https://openalex.org/keywords/adolescent-and-young-adult-oncology', 'display_name': 'Adolescent and Young Adult Oncology', 'score': 0.526007}], 'concepts': [{'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.80809486}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.789191}, {'id': 'https://openalex.org/C120195587', 'wikidata': 'https://www.wikidata.org/wiki/Q2138790', 'display_name': 'Absolute risk reduction', 'level': 3, 'score': 0.7140726}, {'id': 'https://openalex.org/C72563966', 'wikidata': 'https://www.wikidata.org/wiki/Q1303415', 'display_name': 'Cohort', 'level': 2, 'score': 0.6384336}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.61322707}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.56569475}, {'id': 'https://openalex.org/C61511704', 'wikidata': 'https://www.wikidata.org/wiki/Q1671857', 'display_name': 'Incidence (geometry)', 'level': 2, 'score': 0.546684}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.5185245}, {'id': 'https://openalex.org/C201903717', 'wikidata': 'https://www.wikidata.org/wiki/Q1778788', 'display_name': 'Cohort study', 'level': 2, 'score': 0.47067484}, {'id': 'https://openalex.org/C82789193', 'wikidata': 'https://www.wikidata.org/wiki/Q2142611', 'display_name': 'Relative risk', 'level': 3, 'score': 0.44175017}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4029626}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.38633764}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.38174614}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.35634845}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.1262851}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D016609', 'descriptor_name': 'Neoplasms, Second Primary', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D017668', 'descriptor_name': 'Age of Onset', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004307', 'descriptor_name': 'Dose-Response Relationship, Radiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005602', 'descriptor_name': 'France', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D005602', 'descriptor_name': 'France', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015994', 'descriptor_name': 'Incidence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016609', 'descriptor_name': 'Neoplasms, Second Primary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016609', 'descriptor_name': 'Neoplasms, Second Primary', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006113', 'descriptor_name': 'United Kingdom', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006113', 'descriptor_name': 'United Kingdom', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/sj.bjc.6690300', 'pdf_url': 'https://www.nature.com/articles/6690300.pdf', 'source': {'id': 'https://openalex.org/S62966998', 'display_name': 'British Journal of Cancer', 'issn_l': '0007-0920', 'issn': ['0007-0920', '1532-1827'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362818', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10206309', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/sj.bjc.6690300', 'pdf_url': 'https://www.nature.com/articles/6690300.pdf', 'source': {'id': 'https://openalex.org/S62966998', 'display_name': 'British Journal of Cancer', 'issn_l': '0007-0920', 'issn': ['0007-0920', '1532-1827'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.81, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 25, 'referenced_works': ['https://openalex.org/W1803660279', 'https://openalex.org/W1873070501', 'https://openalex.org/W1963611189', 'https://openalex.org/W1967227757', 'https://openalex.org/W1968977630', 'https://openalex.org/W1974649225', 'https://openalex.org/W1975829266', 'https://openalex.org/W1997600268', 'https://openalex.org/W2029803535', 'https://openalex.org/W2030810311', 'https://openalex.org/W2036569777', 'https://openalex.org/W2047955084', 'https://openalex.org/W2052821080', 'https://openalex.org/W2070053454', 'https://openalex.org/W2106782951', 'https://openalex.org/W2124548350', 'https://openalex.org/W2142507479', 'https://openalex.org/W2155869612', 'https://openalex.org/W2169278972', 'https://openalex.org/W2315891151', 'https://openalex.org/W2321358810', 'https://openalex.org/W2338057729', 'https://openalex.org/W2341591060', 'https://openalex.org/W2439503951', 'https://openalex.org/W2440561267'], 'related_works': ['https://openalex.org/W4233135127', 'https://openalex.org/W3211657369', 'https://openalex.org/W2598476089', 'https://openalex.org/W2417555288', 'https://openalex.org/W2387970634', 'https://openalex.org/W2353276349', 'https://openalex.org/W2349204430', 'https://openalex.org/W2347438058', 'https://openalex.org/W2089609493', 'https://openalex.org/W2074828072'], 'abstract_inverted_index': {'The': [0, 54], 'variation': [1, 50, 306], 'in': [2, 81, 93, 127, 298], 'the': [3, 31, 37, 47, 52, 62, 65, 68, 72, 96, 113, 120, 128, 130, 147, 156, 188, 196, 204, 209, 222, 236, 248, 254, 284, 289, 305, 311, 314], 'risk': [4, 225, 290, 309], 'of': [5, 33, 39, 51, 56, 64, 71, 74, 87, 115, 122, 149, 155, 164, 213, 230, 251, 257, 286, 291, 307], 'solid': [6, 75, 171, 214, 292], 'second': [7], 'malignant': [8], 'neoplasms': [9], '(SMN)': [10], 'with': [11, 192, 200, 217, 265, 281], 'time': [12, 218, 312], 'since': [13], 'first': [14, 79, 109, 220, 237, 267, 296, 315], 'cancer': [15, 80, 110, 268, 297], 'during': [16, 227, 310], 'childhood': [17], 'has': [18, 25], 'been': [19, 26], 'previously': [20], 'reported.': [21], 'However,': [22], 'no': [23], 'study': [24, 58], 'performed': [27], 'that': [28], 'controls': [29], 'for': [30, 46, 244, 247], 'distribution': [32, 183], 'radiation': [34, 150, 252], 'dose': [35, 148, 250], 'and': [36, 95, 118, 134, 195, 246], 'aggressiveness': [38], 'past': [40], 'chemotherapy,': [41], 'which': [42], 'could': [43], 'be': [44, 101], 'responsible': [45], 'observed': [48, 186], 'temporal': [49], 'risk.': [53], 'purpose': [55], 'this': [57, 308], 'was': [59, 137, 185], 'to': [60, 100, 174, 253, 275, 277], 'investigate': [61], 'influence': [63], 'treatment': [66], 'on': [67], 'long-term': [69], 'pattern': [70, 184, 240], 'incidence': [73], 'SMN': [76, 215, 293], 'after': [77, 107, 219, 235, 242, 294, 313], 'a': [78, 85, 108, 161, 170, 228, 266, 295], 'childhood.': [82], 'We': [83], 'studied': [84], 'cohort': [86], '4400': [88], 'patients': [89, 190, 198, 264], 'from': [90, 177], 'eight': [91], 'centres': [92], 'France': [94], 'UK.': [97], 'Patients': [98], 'had': [99, 143], 'alive': [102], '3': [103], 'years': [104, 117, 234], 'or': [105, 270], 'more': [106], 'treated': [111, 191, 199], 'before': [112, 119], 'age': [114], '17': [116], 'end': [121], '1985.': [123], 'For': [124, 139], 'each': [125, 140], 'patient': [126, 141], 'cohort,': [129], 'complete': [131], 'clinical,': [132], 'chemotherapy': [133, 245, 287], 'radiotherapy': [135, 193, 201, 282], 'history': [136], 'recorded.': [138], 'who': [142], 'received': [144, 151], 'external': [145], 'radiotherapy,': [146], 'by': [152], '151': [153], 'sites': [154, 256], 'body': [157], 'were': [158], 'estimated.': [159], 'After': [160], 'mean': [162], 'follow-up': [163], '15': [165], 'years,': [166], '113': [167], 'children': [168], 'developed': [169], 'SMN,': [172], 'compared': [173, 280], '12.3': [175], 'expected': [176], 'general': [178], 'population': [179], 'rates.': [180], 'A': [181], 'similar': [182], 'among': [187], '1045': [189], 'alone': [194], '2064': [197], 'plus': [202], 'chemotherapy;': [203], 'relative': [205], 'risk,': [206, 212], 'but': [207, 300], 'not': [208, 302], 'excess': [210, 223], 'absolute': [211, 224], 'decreased': [216], 'treatment;': [221], 'increased': [226], 'period': [229], 'at': [231], 'least': [232], '30': [233], 'cancer.': [238, 316], 'This': [239], 'remained': [241, 261], 'controlling': [243], 'average': [249], 'major': [255], 'SMN.': [258, 278], 'It': [259], 'also': [260], 'when': [262], 'excluding': [263], 'type': [269], 'an': [271], 'associated': [272], 'syndrome': [273], 'known': [274], 'predispose': [276], 'When': [279], 'alone,': [283], 'addition': [285], 'increases': [288], 'childhood,': [299], 'does': [301], 'significantly': [303], 'modify': [304]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2074167455', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-09-13T03:19:11.161990', 'created_date': '2016-06-24'}