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1230, 1290, 1921, 1960, 2089, 2134], 'compound-related': [362], 'materials.': [363], 'analyses': [365], 'during': [366, 1119, 1664], 'sector': [368], 'era': [369], 'conducted': [371], 'highly': [373, 2276], 'specialized': [374], 'involved': [377, 471], 'extensive': [378], 'sample': [379, 382, 2742], 'clean-up': [380], 'concentration': [383], 'steps.': [384], 'However,': [385, 854], 'applications': [388, 1916], 'have': [389, 1016, 1251, 1673, 2847], 'steadily': [390], 'decreased': [391], 'over': [392, 763], 'last': [394, 1121], 'two': [395, 1105, 1432, 1501], 'decades': [396], 'due': [397, 868], 'incompatibilities': [399], 'sources': [402], 'provide': [404, 1652], 'access': [406], 'peptides,': [408], 'proteins,': [409], 'biological': [410, 1592], 'fluids': [411], 'difficulties': [413], 'associated': [414], 'coupling': [416, 708, 1078], 'liquid': [417, 2220, 2322], 'chromatography-based': [418], 'systems.While': [420], 'instrumental': [421], 'on-going,': [429], 'concept': [431, 467], 'linear': [433, 1203, 1935], 'TOF': [434, 1038], 'proposed': [436], '1946': [438], 'William': [440], 'E': [441, 2602, 2781], 'Stephens': [442], 'University': [445], 'Pennsylvania': [447], '(PA,': [448], 'USA)': [449], 'commercially': [451], 'viable': [453], 'late': [456], '1950s': [457, 592], 'through': [458], 'Wiley': [462, 1769, 1779, 2150], 'McLaren': [464, 1781], '[3].': [465], 'The': [466, 540, 794, 915, 1439, 1563, 1581, 1594, 1833, 1996, 2409], 'simple': [469, 1805], 'ions': [472, 611, 937, 956, 986, 991], 'being': [473, 588], 'separated': [474], 'differences': [476], 'their': [478, 940, 2489], 'velocities': [479], 'they': [481], 'move': [482], 'straight': [485], 'path': [486], 'toward': [487], 'collector': [489], 'order': [491], 'increasing': [493, 1645], 'm/z': [494, 964], 'ratio.': [495], 'Until': [496], 'introduction': [498], 'time-lag': [500, 563], 'focusing': [501, 522, 564], 'mid-1980s': [504], 'reflectron': [507, 541, 567], 'mid-1970s,': [510], 'TOFs': [511, 572], 'only': [513], 'capable': [514, 649], 'achieving': [516], 'hundreds.': [520], 'Time-lag': [521], 'improved': [523, 568, 678, 1787, 1809], 'simultaneously': [527], 'correcting': [528], 'initial': [531], 'spatial': [532], 'kinetic': [534, 554], 'energy': [535, 555], 'distributions': [536], 'ions.': [539, 559, 636], 'design,': [542], 'common': [544], 'feature': [545], "today's": [547], 'TOF-based': [548], 'analyzers,': [550, 1093], 'corrects': [551], 'distribution': [556], 'Collectively,': [560], 'implementation': [561], 'hundreds': [575], 'thousands': [577], '[4,5].Two': [578], 'winning': [582], 'analyzer': [584, 895, 1010, 2043], 'designs': [585], 'explored': [589], '1960s': [594], 'Wolfgang': [596], 'Paul': [597], 'co-workers,': [599], 'included': [600], 'quadrupole': [602, 621, 646, 1313, 1855, 1882, 2700], 'trap': [604, 608, 691, 744, 982, 1896, 1937], '(QIT),': [605], 'which': [606, 625, 1442, 1463], 'can': [607, 826, 1435], 'mass-analyze': [610], 'using': [612, 959, 996, 1219, 1287, 1326, 1608, 1635, 2232, 2445, 2491, 2537, 2627, 2799], '3D': [614], 'quadrupolar': [615], 'radiofrequency': [616, 630], 'electric': [617], 'field,': [618], 'filter': [623], '(QMF),': [624], 'uses': [626], 'combination': [628, 972, 998], 'direct': [632, 1859, 2540], 'current': [633, 833, 947], 'separate': [635, 775], 'During': [637, 700], '1970s': [639, 816], '1980s,': [641], 'construction': [642], 'triple': [645, 1312, 2699], 'performing': [651], 'MS/MS': [652, 685], 'experiments': [653], '[6,7]': [654], 'provided': [655], 'huge': [657], 'advance': [658, 1172], 'QMF': [660, 750, 766], 'technology,': [661], 'while': [662], 'incorporation': [663], 'selective': [666, 1033, 2277], 'instability': [667], 'mode': [668], 'operation': [670], 'bath': [672], 'or': [673, 834, 932, 1039, 1047, 1449, 1677, 1683, 1690, 1697, 1710, 1715, 1718, 1720, 2851, 2857, 2864, 2871, 2884, 2889, 2892, 2894], 'damping': [674], 'gas': [675], '(i.e.,': [676, 1446], 'helium)': [677], 'resolution,': [679, 1646], 'peak': [680, 1517, 1538], 'shape,': [681], 'trapping': [682], 'efficiency': [683, 687], 'time': [686, 2083], '[8]': [692], 'allowed': [694, 721], 'QIT–MS': [695], 'technology': [696, 822], 'mature': [698], 'further.': [699], '1990s': [702], '2000s,': [704], 'ease': [706], 'both': [710, 1329], 'atmospheric': [711], 'pressure': [712, 881, 1062], '(API)': [714], 'techniques': [715, 732, 1015, 1084, 1305, 2623], '(ESI': [716], 'APCI)': [718], 'LC': [720, 1080, 1376, 2628], 'QIT-': [722], 'QMF-based': [724], 'evolve': [728], 'into': [729, 1019], 'choice': [734], 'qualitative': [737, 1330], 'quantitative': [739, 1308, 1332, 2543], '[9].': [741], 'Linear': [742], '(LIT),': [745], 'variation': [747], 'QIT': [752, 768], 'analyzer,': [754], 'introduced': [756, 913], '2000s': [759], 'improve': [761], 'performance': [762, 2219], 'conventional': [765], '[10,11].In': [771], '1949,': [772], 'on': [773, 948, 1098, 1114], 'front,': [776], 'an': [777, 798, 929, 945, 988, 2045], 'cyclotron': [779, 2003], 'resonance': [780, 2004], '(ICR)': [781], 'demonstrated': [787], 'Sommer,': [789], 'Thomas': [790, 1975], 'Hipple': [792, 1971], '[12].': [793], 'technique': [795, 2024], 'remained': [796], 'largely': [797], 'academic': [799], 'until': [801], 'application': [803], 'fourier': [805], 'transform': [806, 2001], '(FT)': [807], 'methods': [808], 'Marshall': [810, 1994], 'Comisarow': [812, 1992], 'early': [815, 1997], 'superconducting': [820], 'magnet': [821], '[13].': [823], 'Since': [824], 'frequencies': [825, 960], 'be': [827, 1436, 1457, 1469, 1633], 'measured': [828, 958, 1629], 'more': [829], 'accurately': [830], 'TOF,': [835], 'measurements': [837], 'sub-parts': [839], 'per': [840], 'million': [841], '(ppm)': [842], 'accuracies': [844], '>100,000': [846], 'are': [850, 861, 957, 979, 994, 1256, 1410], 'routine': [851, 856], 'FTICR-MS.': [853], 'metabolism': [857, 1142, 1961], 'studies,': [858, 1295], 'standalone': [859], 'FTICR-MS': [860], 'not': [862], 'considered': [863], 'mainstream': [865], 'practical': [870], 'limitations': [871], 'this': [873, 1108, 1191, 1338, 1730, 2904], 'type': [874, 1637], 'resulting': [878], 'operational': [880], 'requirements': [882], '10-8': [887], '10-10': [889], 'torr.': [890], '2000,': [892], 'another': [893], 'takes': [897], 'advantage': [898], 'FT': [900], 'simultaneous': [902, 2596], 'detection': [903], 'ions,': [908], 'Orbitrap': [910, 2311], '(OT),': [911], '[14,15].': [914], 'OT': [916, 993], 'utilizes': [917], 'electrical': [918], 'fields': [919], 'between': [920, 1375, 1431, 1500, 1509], 'sections': [921], 'roughly': [924], 'egg-shaped': [925], 'outer': [926], 'electrode': [927, 931], 'inner': [930], 'spindle,': [934], 'where': [935, 970], 'orbit': [938], 'oscillation': [941], 'recorded': [943], 'image': [946], 'spindle.': [950], 'Similar': [951], 'FTICR,': [953, 969], 'OT,': [955], 'characteristic': [961], 'values.': [965], 'contrast': [967], 'field': [975], 'electrostatic': [977, 1000], 'potentials': [978], 'manipulate': [984], 'within': [987], 'ICR': [989], 'cell,': [990], 'manipulated': [995], 'potentials.Some': [1001], 'desired': [1004], 'qualities': [1005], 'individual': [1008], 'manipulation': [1014], 'been': [1017], 'combined': [1018, 1043, 2351], 'configure': [1023], 'various': [1024, 1184], 'hybrid': [1025, 1196, 1957], 'spectrometers.': [1027], 'Hybrid': [1028], 'become': [1031, 1158, 1252], 'very': [1032], 'specific': [1035], 'when': [1036], 'either': [1037, 1045], 'FTMS-based': [1040, 1091], 'ITs': [1046], 'QMFs.': [1048], 'example,': [1050], 'ability': [1052], 'LITs': [1054], 'QMFs': [1056], 'operate': [1058], 'vacuum': [1061], '10-5': [1065], '10-6': [1067], 'torr': [1068], 'makes': [1069], 'these': [1070, 1318], 'ideally': [1075], 'suited': [1076], 'API': [1083], 'TOF-': [1089], 'tandem,': [1095], 'capitalizing': [1097], 'latter': [1104], 'analyzers.In': [1107], 'special': [1109, 1239, 1339], 'focus': [1110, 1113, 1240, 1340], 'issue,': [1111], 'we': [1112], 'how': [1115, 1179], 'has': [1117, 1147, 1156, 1349], 'evolved': [1118], 'few': [1122], 'meet': [1125], 'demanding': [1129], 'role': [1130, 1214, 2129], 'bioanalysis,': [1135], 'especially': [1136], 'pharmacokinetics': [1144, 1292], '(DMPK).': [1145], 'What': [1146], 'changed': [1148], 'recent': [1151, 1280], 'past': [1152], 'now': [1157], 'quantitative,': [1162], 'qualitative,': [1166], 'studies': [1168], '[16,17].': [1169], 'This': [1170, 1703, 2877], 'technological': [1171], 'will': [1173, 1210, 2061], 'allow': [1174], 'paradigm': [1176, 1323, 1347, 2086], 'shift': [1177, 1324, 1348, 2087], 'assays': [1186], 'future.': [1189], 'At': [1190], 'writing,': [1192], 'it': [1193, 1343, 1382], 'appears': [1194], 'spectrometers,': [1198], 'orthogonal': [1200], 'acceleration': [1201], 'quadrupole-TOF,': [1202], 'trap-OT': [1205], '(LIT-OT)': [1206], 'quadrupole-OT': [1208], '(Q-OT)': [1209], 'play': [1211], 'major': [1213], 'future': [1217, 2480], 'industry': [1224], 'part': [1226], 'discovery': [1231, 1260, 2090, 2135], 'development': [1233, 1262, 1998], 'process.': [1234], 'As': [1235], 'evident': [1236], 'issue': [1241, 1341], 'articles,': [1242], 'along': [1243], 'UHPLC': [1247, 2492], 'column': [1249], 'technologies': [1250], 'important': [1253], 'tools': [1254, 2730], 'efficacious,': [1264], 'potent': [1265], 'safer': [1267], 'small': [1268, 2469], 'molecular': [1269, 1272], 'weight-,': [1270, 1273], 'middle': [1271], 'peptide-': [1274], 'protein-based': [1276], 'drugs.': [1277], 'Despite': [1278], 'widespread': [1281], 'adoption': [1282], 'benefits': [1285, 2648], 'UHPLC–HRMS': [1288], 'metabolism,': [1291], 'metabonomic': [1294], 'challenges': [1296, 1319], 'around': [1297], 'automated': [1298], 'user-friendly': [1299], 'software': [1300], 'tools,': [1301], 'data': [1302, 2593, 2621], 'file': [1303], 'comparison': [1304, 2697], 'ultimate': [1307], 'sensitivity': [1309, 2693], 'similar': [1310], 'remain': [1315], 'unconquered.': [1316], 'While': [1317], 'may': [1320], 'slow': [1321], 'applications,': [1334], 'articles': [1336], 'make': [1342], 'clear': [1344], 'already': [1350], 'begun.Mass': [1351], 'terminologyIn': [1352], 'most': [1353, 1578, 1618], 'seminal': [1356], 'publications': [1357], '1950s,': [1360], "'R'": [1361], 'rather': [1367, 1391], 'resolution.': [1369, 1788, 1844], 'Nowadays,': [1370], 'additional': [1371], 'confusion': [1372], 'generated': [1374, 1607], 'power.': [1380], 'Therefore,': [1381], 'always': [1384], 'best': [1385], 'state': [1387], "'mass": [1388], "power'": [1390], "'resolving": [1393], "power'.": [1394], 'benefit': [1397], 'readers,': [1400], 'selected': [1408], 'terms': [1409, 2175], 'defined': [1411, 1554], 'following': [1414], '[18–20]:': [1415], '▪': [1416], 'Mass': [1417, 1486, 1494, 1548, 1641, 1734, 1745, 1760, 1818, 1905, 1941, 2008, 2097, 2119, 2139, 2247, 2270, 2310, 2399, 2427], 'power:': [1419], 'spectrum,': [1423], 'observed': [1425], 'divided': [1427], 'difference': [1430, 1498], 'masses': [1433], 'separated:': [1437], 'm/Δm.': [1438], 'procedure': [1440], 'Δm': [1443, 1499], 'obtained': [1445, 1634], '50%': [1447], 'valley': [1448, 1508], 'full': [1450], 'width': [1451], 'at': [1452, 1462, 1540], 'half': [1453], 'maximum': [1454], '[FWHM])': [1455], 'must': [1456], 'given': [1458], 'should': [1468], 'reported': [1470, 1490, 1544], '[20].': [1471, 1519, 1562], 'consistency': [1473], 'avoid': [1476], 'confusion,': [1477], 'authors': [1479, 1672, 2846], 'suggest': [1480], 'MRP': [1481], '=': [1482, 1484], 'm/Δm50': [1483, 1530], 'm/ΔmFWHM.': [1485], 'without': [1491, 1545], 'any': [1492, 1546, 1636, 1681, 2855], 'units;▪': [1493, 1547], 'resolution:': [1495], 'smallest': [1496], 'equal': [1502], 'magnitude': [1503], 'peaks': [1504], 'so': [1505], 'them': [1510], 'specified': [1513], 'fraction': [1514], 'height': [1518], 'To': [1520], 'calculate': [1521], 'single': [1526], 'peak,': [1527], 'formula': [1529], 'still': [1532], 'applicable,': [1533], 'but': [1534, 1647], 'Δm50': [1535], 'determined': [1539], 'FWHM.': [1541], 'Resolution': [1542, 2398], 'unit:': [1549], 'unit': [1552, 1567, 1571, 1589, 1597], '1/12': [1556], 'carbon-12': [1561], 'unified': [1564], 'atomic': [1565, 1595], '(u)': [1568], 'accepted': [1576, 1588], 'spectrometrists.': [1580], 'Dalton': [1582], '(Da)': [1583], 'also': [1585], 'widely': [1587], 'describe': [1591], 'molecules.': [1593], '(amu)': [1598], 'technically': [1600], 'incorrect;▪': [1601], 'Exact': [1602], 'mass:': [1603, 1627], 'calculated': [1605], 'exact': [1610], 'particular': [1614], 'isotope': [1615], '(generally': [1616], 'abundant)': [1619], 'molecule;▪': [1625], 'Accurate': [1626, 2108, 2309], 'could': [1632], 'accuracy': [1642], 'improves': [1643], 'alone': [1650], 'cannot': [1651], 'measurements,': [1655], 'stable': [1659], 'mass–axis': [1660], 'calibration': [1661], 'necessary': [1663], 'analysis.Financial': [1667], 'competing': [1669, 2843], 'interests': [1670, 2844], 'disclosureThe': [1671, 2845], 'no': [1674, 2848], 'relevant': [1675, 2849], 'affiliations': [1676, 2850], 'financial': [1678, 1687, 1691, 2852, 2861, 2865], 'involvement': [1679, 2853], 'organization': [1682, 2856], 'entity': [1684, 2858], 'interest': [1688, 2862], 'conflict': [1692, 2866], 'subject': [1695, 2869], 'matter': [1696, 2870], 'materials': [1698, 2872], 'discussed': [1699, 2873], 'manuscript.': [1702, 2876], 'includes': [1704, 2878], 'employment,': [1705, 2879], 'consultancies,': [1706, 2880], 'honoraria,': [1707, 2881], 'stock': [1708, 2882], 'ownership': [1709, 2883], 'options,': [1711, 2885], 'expert': [1712, 2886], 'testimony,': [1713, 2887], 'grants': [1714, 2888], 'patents': [1716, 2890], 'received': [1717, 2891], 'pending,': [1719, 2893], 'royalties.No': [1721, 2895], 'writing': [1722, 2896], 'assistance': [1723, 2897], 'production': [1728, 2902], 'manuscript.References1': [1731], 'Bauer': [1732], 'SH.': [1733], 'spectrometry': [1735, 1857, 2060, 2132, 2326, 2350, 2722, 2727], "mid-1930's:": [1738], 'chemists': [1740], 'intrigued?': [1741], 'J.': [1742, 1817, 1885, 1902, 2007, 2096, 2116, 2292], 'Am.': [1743, 1886, 1903, 2117], 'Soc.': [1744, 1904, 2118], 'Spectrom.12,975–988': [1746], '(2001).Crossref,': [1747], 'CAS,': [1748, 1793, 1869, 1890, 1909, 1928, 1944, 1968, 2012, 2032, 2053, 2070, 2101], 'Google': [1749, 1794, 1823, 1870, 1891, 1910, 1929, 1945, 1969, 1990, 2013, 2033, 2054, 2071, 2102, 2122], 'Scholar2': [1750], 'Becker': [1751, 1765], 'S.': [1752], 'History': [1753, 2827], 'spectrometric': [1756], 'techniques.': [1757], 'In:': [1758, 2138], 'Inorganic': [1759], 'Spectrometry:': [1761], 'Principles': [1762, 1914], 'Applications.': [1764], 'S': [1766, 2078], '(Ed.).': [1767, 2148], 'Sons,': [1771, 2152], 'Inc.,': [1772, 2153], 'Hoboken,': [1773, 2154], 'NJ,': [1774, 2155], 'USA': [1775, 2156], '7–22': [1776], '(2007).Google': [1777], 'Scholar3': [1778], 'WC,': [1780], 'IH.': [1782], 'Time-of-flight': [1783], 'Rev.': [1789], 'Sci.': [1790], 'Instrum.26,1150': [1791], '(1955).Crossref,': [1792], 'Scholar4': [1795], 'Kinsel': [1796], 'GR,': [1797], 'Johnston': [1798], 'MV.': [1799], 'Post': [1800], 'pulse': [1802], 'focusing:': [1803], 'method': [1806, 1979, 2222], 'achieve': [1808], 'time-of-flight': [1813, 1839], 'spectrometer.': [1815, 1884, 1938], 'Int.': [1816], 'Spectrom.': [1819], 'Ion': [1820, 1895], 'Processes157–176': [1821], '(1989).Crossref,': [1822], 'Scholar5': [1824], 'Mamyrin': [1825], 'BA,': [1826], 'Karctaev': [1827], 'VI,': [1828], 'Shmink': [1829], 'DV,': [1830], 'Zagulin': [1831], 'VA.': [1832], 'reflectron,': [1835], 'nonmagnetic': [1838], 'Sov.': [1845], 'Phys.': [1846, 1987], 'JETP37,45–48': [1847], '(1973).Google': [1848], 'Scholar6': [1849], 'Yost': [1850, 1872], 'RA,': [1851, 1873], 'Enke': [1852, 1874], 'CG.': [1853, 1875], 'Triple': [1854], 'mixture': [1860], 'analysis': [1861, 2667, 2798], 'structure': [1863], 'elucidation.': [1864], 'Anal.': [1865, 2028, 2049], 'Chem.51,1251A–1264A': [1866], '(1979).Crossref,': [1867], 'Medline,': [1868, 1908, 1927, 1967, 2011, 2031, 2052, 2100], 'Scholar7': [1871], 'Selected': [1876], 'fragmentation': [1878], 'tandem': [1881, 2720], 'Chem.': [1887], 'Soc.100,2274–2275': [1888], '(1978).Crossref,': [1889], 'Scholar8': [1892], 'Stafford': [1893], 'G.': [1894], 'spectrometry:': [1898, 2449], 'A': [1899, 1933, 1977, 2298, 2553, 2784], 'personal': [1900], 'perspective.': [1901], 'Spectrom.13(6),589–596': [1906], '(2002).Crossref,': [1907, 1943], 'Scholar9': [1911], 'Korfmacher': [1912, 2056, 2384], 'WA.': [1913], 'LC-MS': [1918], 'discovery.': [1922], 'Discov.': [1924], 'Today10(20),1357–1367': [1925], '(2005).Crossref,': [1926], 'Scholar10': [1930], 'Hager': [1931], 'JW.': [1932], 'Rapid': [1939], 'Commun.': [1940], 'Spectrom.16,512–526': [1942], 'Scholar11': [1946], 'Sanders': [1947], 'M,': [1948, 2036, 2076], 'Shipkova': [1949], 'PA,': [1950], 'Zhang': [1951], 'H,': [1952, 1974], 'Warrack': [1953], 'BM.': [1954], 'Utility': [1955], 'LTQ-FTMS': [1958], 'applications.': 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[2167], 'Li': [2168], 'L,': [2169], 'Naito': [2170], 'Y.': [2171], 'Standard': [2172], 'definitions': [2173], 'relating': [2176], 'spectrometry,': [2179], 'international': [2180], 'union': [2181], 'pure': [2183], 'applied': [2185], 'chemistry': [2186], '(IUPAC),': [2187], 'Analytical': [2188, 2241, 2341, 2459], 'Chemistry': [2189], 'Division': [2190], '(2006).Google': [2191], 'ScholarFiguresReferencesRelatedDetailsCited': [2192], 'ByPeptide': [2193], 'Linker': [2194], 'Affecting': [2195], 'Activity': [2197], 'Retention': [2198], 'Rate': [2199], 'VHH': [2201], 'Immunosorbents27': [2203], 'November': [2204], '2020': [2205, 2239], '|': [2206, 2240, 2263, 2303, 2340, 2376, 2390, 2408, 2458, 2511, 2560, 2580, 2613, 2640, 2661, 2686, 2711, 2757, 2792, 2814], 'Biomolecules,': [2207], 'Vol.': [2208, 2243, 2272, 2305, 2345, 2378, 2392, 2412, 2431, 2463, 2513, 2562, 2582, 2615, 2642, 2663, 2688, 2713, 2739, 2759, 2794, 2816, 2820], '10,': [2209], '12A': [2211], 'simple,': [2212], 'sensitive,': 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'King-Ahmad,': [2293], 'Christopher': [2294, 2552], 'L': [2295, 2507], 'Holliman': [2296], 'David': [2299, 2604], 'Rodrigues5': [2300], 'October': [2301, 2509], '2017': [2302, 2339], 'Bioanalysis,': [2304, 2377, 2391, 2512, 2561, 2581, 2614, 2641, 2662, 2687, 2712, 2758, 2793, 2815], '9,': [2306, 2379], '22High‐Resolution': [2308], 'Its': [2313], 'Application': [2314], 'Protein': [2316], 'Therapeutics': [2317], 'Bioanalysis2': [2318], 'June': [2319], '2017An': [2320], 'efficient': [2321], 'chromatography-high': [2323], 'approach': [2327, 2547], 'optimization': [2330], 'metabolic': [2333], 'stability': [2334], 'peptides30': [2337], 'Bioanalytical': [2343, 2461], 'Chemistry,': [2344, 2462], '409,': [2346], '10Differential': [2348], 'mobility': [2349], 'multiple': [2353], 'disulfide-bonded': [2359], 'peptides': [2360], 'inefficient': [2362], 'collision-induced': [2363], 'dissociation': [2364], 'fragmentationYuan-Qing': [2365], 'Xia,': [2366], 'Eugene': [2367], 'Ciccimaro,': [2368], 'Naiyu': [2369], 'Zheng': [2370], 'Mingshe': [2372], 'Zhu14': [2373], '2016': [2375, 2389], '2HRMS': [2381], 'DMPKWalter': [2383], 'Ragu': [2386], 'Ramanathan3': [2387], 'August': [2388, 2527, 2558, 2812], '8,': [2393], '16Pharmacokinetic': [2395], 'MethodsLiquid': [2396], 'Chromatography-High': [2397], 'Peptide': [2402], 'Quality': [2404], 'Control26': [2405], 'February': [2406], '2015': [2407], 'AAPS': [2410], 'Journal,': [2411], '17,': [2413], '3Improved': [2415], 'Investigations': [2416], 'Safety': [2419], 'More': [2421], 'In-Depth': [2422], 'Individual': [2423], 'Pharmacokinetics': [2424], 'Using': [2425], 'High-Resolution': [2426], 'SpectrometryTherapeutic': [2428], 'Monitoring,': [2430], '37,': [2432], '2Quantitative': [2434], 'tamoxifen': [2437], 'human': [2439], 'plasma': [2440, 2536], 'extended': [2441], '40': [2443], 'liquid-chromatography': [2446], 'investigation': [2451], 'clinical': [2454, 2806, 2809], 'pharmacology16': [2455], 'March': [2456, 2831, 2836], '2014': [2457], 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