Title: Oxidative Enamine Catalysis: Direct Catalytic Enantioselective β‐Functionalization of Aldehydes
Abstract: Jekyll and aldeHyde: The oxidation of enamines to iminium species by 2-iodoxybenzoic acid (IBX) or 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) catalyzed by a chiral secondary amine catalyst enabled the unprecedented enantioselective β-functionalization of aldehydes with various nucleophiles in high stereoselectivity.
Publication Year: 2012
Publication Date: 2012-03-14
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 27
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