High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys

Name: Work Video:
Duration: 3 min 30 s
Ousmane M. Diop; Aïssatou Guèye; Marisa Dias-Tavares; C.G. Kornfeld; Abdourahmane Faye; Patrick Avé; Michel Huerre; Sylvie Corbet; Françoise Barré‐Sinoussi; Michaela Müller‐Trutwin
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[114], 'DNA': [116, 124, 154, 200, 271, 302], 'load': [118, 136, 156], '(10': [119, 266], '4': [120, 199, 241, 306, 335], 'copies/10': [125, 189, 201, 272, 337], '6': [126, 140, 187, 190, 202, 273, 316, 338], 'mononuclear': [129], 'cells': [130], '[PBMC]),': [131], 'plasma': [133], 'RNA': [134, 146, 152, 188, 285, 312, 336], '(2': [137], '×': [138, 143, 180, 185, 277, 282, 296, 309, 333], '8': [145], 'copies/ml).': [147], 'The': [148], 'lymph': [149], 'node': [150], '(LN)': [151], 'were': [158, 204, 226], 'similar': [159, 256], 'those': [161, 211, 258], 'blood,': [163, 221], 'peaks': [165], 'between': [167], '14.': [172], 'These': [173], 'values': [174, 255], 'LNs': [176, 218], '(ranging': [177], 'from': [178], 'LN': [191, 355], 'cell': [192, 352], '[LNC]': [193], 'LNC)': [203], 'no': [206, 246], 'time': [207], 'point': [208], 'higher': [209], 'than': [210, 391], 'blood.': [215], 'Both': [216], 'significant': [224], 'decreases': [225], 'all': [229], 'infected': [230], 'animals': [231], 'after': [232], 'this': [233], 'replication.': [237, 405], 'Within': [238], 'p.i.,': [243], 'longer': [247], 'detectable': [248], 'decreased': [253], 'characteristic': [259], 'phase': [263], 'PBMC': [274], 'copies/ml': [286], 'plasma).': [288], 'LNs,': [290], 'declined': [293], '1': [298], 'copies': [303, 313], 'per': [314], 'LNC': [317], '28': [320], 'p.i.': [321, 329], 'continued': [323], 'decrease': [325], 'until': [326], '84': [328], '(&lt;10': [330], 'LNC).': [339], 'Despite': [340], 'extensive': [341], 'primary': [344], 'infection,': [345, 389], 'neither': [346], 'follicular': [347], 'hyperplasia': [348], 'nor': [349], 'CD8': [350], '+': [351], 'infiltration': [353], 'into': [354], 'germinal': [356], 'centers': [357], 'detected.': [359], 'Altogether,': [360], 'results': [362], 'indicate': [363], 'nonpathogenic': [366], 'outcome': [367], 'its': [372], 'natural': [373], 'host': [374, 400], 'is': [375], 'associated': [376], 'a': [378, 393, 398], 'rapidly': [379], 'induced': [380], 'control': [381], 'response': [386], 'rather': [390], 'poorly': [394], 'replicating': [395], 'or': [397], 'constitutive': [399], 'genetic': [401], 'resistance': [402]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2072794122', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 26}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-31T03:25:32.198175', 'created_date': '2016-06-24'}
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