Abstract: Every field has a favourite and, in cell biology, the centrosome has always been on the top of many a researcher's list. The centrosome organizes microtubules and is found in a juxtanuclear position during interphase and at the poles of mitotic spindles. Centrosomes consist of a pericentriolar matrix, which nucleates the microtubules; at their centre are two barrel-shaped entities 0.5 μm in length called centrioles. The function of centrioles is unknown besides that, without them, vertebrate cells seem unable to divide. How or when during the cell cycle these tiny centrioles assemble are also unanswered questions; previous EM studies have shown that one of the two centrioles is the older and therefore called the 'mother' – the other, younger, centriole is called the 'daughter'.
Publication Year: 2000
Publication Date: 2000-07-01
Language: en
Type: article
Indexed In: ['crossref']
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