Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2071704583', 'doi': 'https://doi.org/10.1016/j.cellsig.2006.07.001', 'title': 'Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space', 'display_name': 'Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space', 'publication_year': 2006, 'publication_date': '2006-09-12', 'ids': {'openalex': 'https://openalex.org/W2071704583', 'doi': 'https://doi.org/10.1016/j.cellsig.2006.07.001', 'mag': '2071704583', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16963225'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cellsig.2006.07.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113768434', 'display_name': 'Cellular Signalling', 'issn_l': '0898-6568', 'issn': ['0898-6568', '1873-3913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5069434243', 'display_name': 'Motohiro Tani', 'orcid': 'https://orcid.org/0000-0003-4316-8260'}, 'institutions': [{'id': 'https://openalex.org/I205349734', 'display_name': 'Hokkaido University', 'ror': 'https://ror.org/02e16g702', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I205349734']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Motohiro Tani', 'raw_affiliation_strings': ['Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12. Nishi 6, Kita-ku, Sapporo 060-0812, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12. Nishi 6, Kita-ku, Sapporo 060-0812, Japan', 'institution_ids': ['https://openalex.org/I205349734']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101544131', 'display_name': 'Makoto Ito', 'orcid': 'https://orcid.org/0000-0003-3159-7818'}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Makoto Ito', 'raw_affiliation_strings': ['Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010830182', 'display_name': 'Yasuyuki Igarashi', 'orcid': 'https://orcid.org/0000-0001-7054-1097'}, 'institutions': [{'id': 'https://openalex.org/I205349734', 'display_name': 'Hokkaido University', 'ror': 'https://ror.org/02e16g702', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I205349734']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasuyuki Igarashi', 'raw_affiliation_strings': ['Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12. Nishi 6, Kita-ku, Sapporo 060-0812, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12. Nishi 6, Kita-ku, Sapporo 060-0812, Japan', 'institution_ids': ['https://openalex.org/I205349734']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3010, 'currency': 'USD', 'value_usd': 3010, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.813, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 149, 'citation_normalized_percentile': {'value': 0.999686, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '19', 'issue': '2', 'first_page': '229', 'last_page': '237'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11308', 'display_name': 'Sphingolipid Signalling and Metabolism in Health and Disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11308', 'display_name': 'Sphingolipid Signalling and Metabolism in Health and Disease', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10407', 'display_name': 'Lipid Rafts and Membrane Dynamics', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10617', 'display_name': 'Mechanisms of Intracellular Membrane Trafficking', 'score': 0.9913, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sphingolipid', 'display_name': 'Sphingolipid', 'score': 0.8567938}, {'id': 'https://openalex.org/keywords/sphingosine-1-phosphate', 'display_name': 'Sphingosine-1-Phosphate', 'score': 0.546675}, {'id': 'https://openalex.org/keywords/sphingosine-kinase', 'display_name': 'Sphingosine Kinase', 'score': 0.519109}, {'id': 'https://openalex.org/keywords/second-messenger-system', 'display_name': 'Second messenger system', 'score': 0.46781468}], 'concepts': [{'id': 'https://openalex.org/C2778703144', 'wikidata': 'https://www.wikidata.org/wiki/Q46298', 'display_name': 'Sphingosine', 'level': 3, 'score': 0.9162519}, {'id': 'https://openalex.org/C2777851122', 'wikidata': 'https://www.wikidata.org/wiki/Q424213', 'display_name': 'Ceramide', 'level': 3, 'score': 0.8683853}, {'id': 'https://openalex.org/C61705674', 'wikidata': 'https://www.wikidata.org/wiki/Q410395', 'display_name': 'Sphingolipid', 'level': 2, 'score': 0.8567938}, {'id': 'https://openalex.org/C180899940', 'wikidata': 'https://www.wikidata.org/wiki/Q117982', 'display_name': 'Lipid signaling', 'level': 3, 'score': 0.82239455}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.7911012}, {'id': 'https://openalex.org/C2777700496', 'wikidata': 'https://www.wikidata.org/wiki/Q7576797', 'display_name': 'Sphingosine kinase', 'level': 5, 'score': 0.7586178}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.63507015}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.6139583}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.5845519}, {'id': 'https://openalex.org/C2776596873', 'wikidata': 'https://www.wikidata.org/wiki/Q418267', 'display_name': 'Sphingosine-1-phosphate', 'level': 4, 'score': 0.5346443}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5257453}, {'id': 'https://openalex.org/C61322309', 'wikidata': 'https://www.wikidata.org/wiki/Q423143', 'display_name': 'Sphingomyelin', 'level': 3, 'score': 0.52314603}, {'id': 'https://openalex.org/C163235415', 'wikidata': 'https://www.wikidata.org/wiki/Q899814', 'display_name': 'Second messenger system', 'level': 3, 'score': 0.46781468}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.34568703}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.26690274}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.19948128}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.103607535}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002518', 'descriptor_name': 'Ceramides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005110', 'descriptor_name': 'Extracellular Space', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008246', 'descriptor_name': 'Lysophospholipids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013110', 'descriptor_name': 'Sphingosine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D013110', 'descriptor_name': 'Sphingosine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000581', 'descriptor_name': 'Amidohydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000581', 'descriptor_name': 'Amidohydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055572', 'descriptor_name': 'Ceramidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002518', 'descriptor_name': 'Ceramides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005110', 'descriptor_name': 'Extracellular Space', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007421', 'descriptor_name': 'Intestine, Small', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008246', 'descriptor_name': 'Lysophospholipids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D008246', 'descriptor_name': 'Lysophospholipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055576', 'descriptor_name': 'Neutral Ceramidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013107', 'descriptor_name': 'Sphingolipids', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D013107', 'descriptor_name': 'Sphingolipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013108', 'descriptor_name': 'Sphingomyelin Phosphodiesterase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013108', 'descriptor_name': 'Sphingomyelin Phosphodiesterase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013110', 'descriptor_name': 'Sphingosine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013110', 'descriptor_name': 'Sphingosine', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cellsig.2006.07.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S113768434', 'display_name': 'Cellular Signalling', 'issn_l': '0898-6568', 'issn': ['0898-6568', '1873-3913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16963225', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 98, 'referenced_works': ['https://openalex.org/W112886495', 'https://openalex.org/W128536076', 'https://openalex.org/W1510083318', 'https://openalex.org/W1595397037', 'https://openalex.org/W1598200894', 'https://openalex.org/W1607948351', 'https://openalex.org/W1678039705', 'https://openalex.org/W1775391605', 'https://openalex.org/W1815757713', 'https://openalex.org/W1866947448', 'https://openalex.org/W1947888345', 'https://openalex.org/W1966929992', 'https://openalex.org/W1967982487', 'https://openalex.org/W1972186900', 'https://openalex.org/W1973573934', 'https://openalex.org/W1973707729', 'https://openalex.org/W1974299852', 'https://openalex.org/W1974620451', 'https://openalex.org/W1975532575', 'https://openalex.org/W198273110', 'https://openalex.org/W1984745753', 'https://openalex.org/W1986426214', 'https://openalex.org/W1988712957', 'https://openalex.org/W1991115604', 'https://openalex.org/W1993449698', 'https://openalex.org/W1993686652', 'https://openalex.org/W1993958404', 'https://openalex.org/W1994248356', 'https://openalex.org/W1996175290', 'https://openalex.org/W1997451186', 'https://openalex.org/W1998949162', 'https://openalex.org/W2003575648', 'https://openalex.org/W2004142844', 'https://openalex.org/W2005071794', 'https://openalex.org/W2006985918', 'https://openalex.org/W2007878869', 'https://openalex.org/W2015613560', 'https://openalex.org/W2016087648', 'https://openalex.org/W2017393429', 'https://openalex.org/W2017659962', 'https://openalex.org/W2017956091', 'https://openalex.org/W2018547009', 'https://openalex.org/W2019877029', 'https://openalex.org/W2022254455', 'https://openalex.org/W2022497999', 'https://openalex.org/W2022770236', 'https://openalex.org/W2023166258', 'https://openalex.org/W2023716261', 'https://openalex.org/W2026057304', 'https://openalex.org/W2032315776', 'https://openalex.org/W2033164168', 'https://openalex.org/W2036300688', 'https://openalex.org/W2037892813', 'https://openalex.org/W2039321321', 'https://openalex.org/W2039375023', 'https://openalex.org/W2041767551', 'https://openalex.org/W2043538113', 'https://openalex.org/W2046390179', 'https://openalex.org/W2047231993', 'https://openalex.org/W2050243165', 'https://openalex.org/W2050892074', 'https://openalex.org/W2054826743', 'https://openalex.org/W2055816456', 'https://openalex.org/W2067017343', 'https://openalex.org/W2071515061', 'https://openalex.org/W2074501013', 'https://openalex.org/W2076691840', 'https://openalex.org/W2076829309', 'https://openalex.org/W2078957898', 'https://openalex.org/W2081578928', 'https://openalex.org/W2084537433', 'https://openalex.org/W2085488090', 'https://openalex.org/W2086735270', 'https://openalex.org/W2089440412', 'https://openalex.org/W2089632091', 'https://openalex.org/W2098782828', 'https://openalex.org/W2099504624', 'https://openalex.org/W2101046775', 'https://openalex.org/W2104063907', 'https://openalex.org/W2105192692', 'https://openalex.org/W2106121689', 'https://openalex.org/W2110184627', 'https://openalex.org/W2121936687', 'https://openalex.org/W2132579946', 'https://openalex.org/W2132805096', 'https://openalex.org/W2137628898', 'https://openalex.org/W2141429256', 'https://openalex.org/W2148670577', 'https://openalex.org/W2151603054', 'https://openalex.org/W2153022420', 'https://openalex.org/W2154089780', 'https://openalex.org/W2157209209', 'https://openalex.org/W2161755258', 'https://openalex.org/W2165944109', 'https://openalex.org/W2177288739', 'https://openalex.org/W2193052968', 'https://openalex.org/W4232576177', 'https://openalex.org/W4248082537'], 'related_works': ['https://openalex.org/W3031778006', 'https://openalex.org/W29294999', 'https://openalex.org/W2356739021', 'https://openalex.org/W2111942396', 'https://openalex.org/W2084654786', 'https://openalex.org/W2041622229', 'https://openalex.org/W2014239065', 'https://openalex.org/W2009993180', 'https://openalex.org/W1567111656', 'https://openalex.org/W114681587'], 'abstract_inverted_index': {'Sphingolipid': [0], 'metabolites,': [1], 'ceramide,': [2], 'sphingosine,': [3], 'and': [4, 92, 97, 114], 'sphingosine': [5, 98], '1-phosphate,': [6], 'have': [7, 58], 'emerged': [8], 'as': [9, 28, 44], 'a': [10], 'new': [11], 'class': [12], 'of': [13, 16, 80, 106], 'lipid': [14], 'biomodulators': [15], 'various': [17], 'cell': [18, 52], 'functions.': [19], 'These': [20], 'metabolites': [21, 109], 'are': [22, 101], 'known': [23], 'to': [24, 51], 'function': [25, 64], 'not': [26, 65], 'only': [27, 66], 'intracellular': [29, 68], 'second': [30], 'messengers,': [31], 'but': [32, 70], 'also': [33, 59, 71], 'in': [34, 67, 72, 103, 110], 'the': [35, 73, 77, 81, 88, 104, 107, 116], 'extracellular': [36, 47, 74, 112], 'space.': [37], 'Sphingosine': [38], '1-phosphate': [39], 'especially': [40], 'has': [41], 'numerous': [42], 'functions': [43], 'an': [45], 'important': [46], 'mediator': [48], 'that': [49, 61, 100], 'binds': [50], 'surface': [53], 'S1P': [54], 'receptors.': [55], 'Recent': [56], 'studies': [57], 'shown': [60], 'sphingolipid-metabolizing': [62], 'enzymes': [63, 90], 'organelles': [69], 'spaces,': [75, 113], 'including': [76], 'outer': [78], 'leaflet': [79], 'plasma': [82], 'membrane.': [83], 'This': [84], 'review': [85], 'focuses': [86], 'on': [87, 115], 'metabolic': [89, 117], '(acid': [91], 'alkaline': [93], 'sphingomyelinases,': [94], 'neutral': [95], 'ceramidase,': [96], 'kinase)': [99], 'involved': [102], 'production': [105], 'sphingolipid': [108], 'these': [111], 'pathway': [118], 'itself.': [119]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2071704583', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 13}], 'updated_date': '2024-09-19T06:16:55.599363', 'created_date': '2016-06-24'}