Title: Cortisol Stimulation of Parathyroid Hormone Secretion by Rat Parathyroid Glands in Organ Culture
Abstract: Addition of cortisol (10 -6 to 10 -8 M ) and related glucocorticoid congeners to cultures of rat parathyroid glands stimulated dose-related increases in parathyroid hormone secretion; the addition of deoxycorticosterone or cortexolone was without effect. Cortexolone, however, inhibited the stimulatory activity of cortisol when both were added to the culture medium. This direct stimulatory effect of cortisol on parathyroid gland secretion may account in part for the increased concentration of parathyroid hormone in the serum of cortisol-treated animals.
Publication Year: 1976
Publication Date: 1976-09-10
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 87
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot