Publication Information

{'id': 'https://openalex.org/W2071488647', 'doi': 'https://doi.org/10.1073/pnas.0608384104', 'title': 'Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex', 'display_name': 'Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex', 'publication_year': 2007, 'publication_date': '2007-02-22', 'ids': {'openalex': 'https://openalex.org/W2071488647', 'doi': 'https://doi.org/10.1073/pnas.0608384104', 'mag': '2071488647', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17360692', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1802728'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.0608384104', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1802728?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081700075', 'display_name': 'Jitesh D. Kawedia', 'orcid': 'https://orcid.org/0000-0001-9685-9378'}, 'institutions': [{'id': 'https://openalex.org/I4210091339', 'display_name': 'Laboratory of Molecular Genetics', 'ror': 'https://ror.org/00fwhek95', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210091339']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Jitesh D. Kawedia', 'raw_affiliation_strings': ['Departments of *Molecular Genetics, Biochemistry, and Microbiology,'], 'affiliations': [{'raw_affiliation_string': 'Departments of *Molecular Genetics, Biochemistry, and Microbiology,', 'institution_ids': ['https://openalex.org/I4210091339']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089490528', 'display_name': 'Michelle L. Nieman', 'orcid': 'https://orcid.org/0000-0001-8504-6697'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Michelle L. Nieman', 'raw_affiliation_strings': ['Molecular and Cellular Physiology, and'], 'affiliations': [{'raw_affiliation_string': 'Molecular and Cellular Physiology, and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054016513', 'display_name': 'Gregory P. Boivin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gregory P. Boivin', 'raw_affiliation_strings': ['Pathology and Molecular Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0524;'], 'affiliations': [{'raw_affiliation_string': 'Pathology and Molecular Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0524;', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058665792', 'display_name': 'James E. Melvin', 'orcid': 'https://orcid.org/0000-0001-7456-1175'}, 'institutions': [{'id': 'https://openalex.org/I5388228', 'display_name': 'University of Rochester', 'ror': 'https://ror.org/022kthw22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I5388228']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James E. Melvin', 'raw_affiliation_strings': ['Center for Oral Biology, University of Rochester, Rochester, NY 14642; and'], 'affiliations': [{'raw_affiliation_string': 'Center for Oral Biology, University of Rochester, Rochester, NY 14642; and', 'institution_ids': ['https://openalex.org/I5388228']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111840948', 'display_name': 'Kenichiro Kikuchi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I75929689', 'display_name': 'UConn Health', 'ror': 'https://ror.org/02kzs4y22', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I75929689']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ken-Ichiro Kikuchi', 'raw_affiliation_strings': ['School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030'], 'affiliations': [{'raw_affiliation_string': 'School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030', 'institution_ids': ['https://openalex.org/I75929689']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077140385', 'display_name': 'Arthur R. Hand', 'orcid': 'https://orcid.org/0000-0003-1519-3573'}, 'institutions': [{'id': 'https://openalex.org/I75929689', 'display_name': 'UConn Health', 'ror': 'https://ror.org/02kzs4y22', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I75929689']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Arthur R. Hand', 'raw_affiliation_strings': ['School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030'], 'affiliations': [{'raw_affiliation_string': 'School of Dental Medicine, University of Connecticut Health Center, Farmington, CT 06030', 'institution_ids': ['https://openalex.org/I75929689']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017319962', 'display_name': 'John N. Lorenz', 'orcid': 'https://orcid.org/0000-0003-2161-9833'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'John N. Lorenz', 'raw_affiliation_strings': ['Molecular and Cellular Physiology, and'], 'affiliations': [{'raw_affiliation_string': 'Molecular and Cellular Physiology, and', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103061532', 'display_name': 'Anil G. Menon', 'orcid': 'https://orcid.org/0000-0003-3794-0197'}, 'institutions': [{'id': 'https://openalex.org/I4210091339', 'display_name': 'Laboratory of Molecular Genetics', 'ror': 'https://ror.org/00fwhek95', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210091339']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Anil G. Menon', 'raw_affiliation_strings': ['Departments of *Molecular Genetics, Biochemistry, and Microbiology,'], 'affiliations': [{'raw_affiliation_string': 'Departments of *Molecular Genetics, Biochemistry, and Microbiology,', 'institution_ids': ['https://openalex.org/I4210091339']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.017, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 130, 'citation_normalized_percentile': {'value': 0.999711, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '104', 'issue': '9', 'first_page': '3621', 'last_page': '3626'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11872', 'display_name': 'Barrier Structure and Function Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11872', 'display_name': 'Barrier Structure and Function Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10724', 'display_name': 'Ion Transport and Channel Regulation', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11480', 'display_name': 'Connexins and lens biology', 'score': 0.9807, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/paracellular-transport', 'display_name': 'Paracellular transport', 'score': 0.9938091}, {'id': 'https://openalex.org/keywords/transcellular', 'display_name': 'Transcellular', 'score': 0.9694828}, {'id': 'https://openalex.org/keywords/occludin', 'display_name': 'Occludin', 'score': 0.8208519}, {'id': 'https://openalex.org/keywords/claudin', 'display_name': 'Claudin', 'score': 0.63962436}, {'id': 'https://openalex.org/keywords/water-transport', 'display_name': 'Water Transport', 'score': 0.4779037}, {'id': 'https://openalex.org/keywords/adherens-junction', 'display_name': 'Adherens junction', 'score': 0.42529124}], 'concepts': [{'id': 'https://openalex.org/C60903277', 'wikidata': 'https://www.wikidata.org/wiki/Q2051926', 'display_name': 'Paracellular transport', 'level': 4, 'score': 0.9938091}, {'id': 'https://openalex.org/C176285220', 'wikidata': 'https://www.wikidata.org/wiki/Q7833830', 'display_name': 'Transcellular', 'level': 2, 'score': 0.9694828}, {'id': 'https://openalex.org/C2775962179', 'wikidata': 'https://www.wikidata.org/wiki/Q2013337', 'display_name': 'Occludin', 'level': 3, 'score': 0.8208519}, {'id': 'https://openalex.org/C177779419', 'wikidata': 'https://www.wikidata.org/wiki/Q1053832', 'display_name': 'Tight junction', 'level': 2, 'score': 0.6692221}, {'id': 'https://openalex.org/C51872919', 'wikidata': 'https://www.wikidata.org/wiki/Q420863', 'display_name': 'Claudin', 'level': 3, 'score': 0.63962436}, {'id': 'https://openalex.org/C2992163139', 'wikidata': 'https://www.wikidata.org/wiki/Q155930', 'display_name': 'Water transport', 'level': 3, 'score': 0.4779037}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45036954}, {'id': 'https://openalex.org/C29350253', 'wikidata': 'https://www.wikidata.org/wiki/Q189073', 'display_name': 'Cell junction', 'level': 3, 'score': 0.44962958}, {'id': 'https://openalex.org/C154280991', 'wikidata': 'https://www.wikidata.org/wiki/Q623090', 'display_name': 'Aquaporin', 'level': 2, 'score': 0.4441692}, {'id': 'https://openalex.org/C201508349', 'wikidata': 'https://www.wikidata.org/wiki/Q45173', 'display_name': 'Adherens junction', 'level': 4, 'score': 0.42529124}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.41088578}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4079598}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.34815735}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.33948454}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.26912636}, {'id': 'https://openalex.org/C120882062', 'wikidata': 'https://www.wikidata.org/wiki/Q28352', 'display_name': 'Permeability (electromagnetism)', 'level': 3, 'score': 0.24357498}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.22199422}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.19904101}, {'id': 'https://openalex.org/C2988574769', 'wikidata': 'https://www.wikidata.org/wiki/Q2259545', 'display_name': 'Water flow', 'level': 2, 'score': 0.07947409}, {'id': 'https://openalex.org/C149402561', 'wikidata': 'https://www.wikidata.org/wiki/Q24776048', 'display_name': 'Cadherin', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C87717796', 'wikidata': 'https://www.wikidata.org/wiki/Q146326', 'display_name': 'Environmental engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D051402', 'descriptor_name': 'Aquaporin 5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014867', 'descriptor_name': 'Water', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051402', 'descriptor_name': 'Aquaporin 5', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051402', 'descriptor_name': 'Aquaporin 5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062465', 'descriptor_name': 'Claudin-3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057167', 'descriptor_name': 'Claudins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003911', 'descriptor_name': 'Dextrans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016650', 'descriptor_name': 'Fluorescein-5-isothiocyanate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016650', 'descriptor_name': 'Fluorescein-5-isothiocyanate', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046529', 'descriptor_name': 'Microscopy, Electron, Transmission', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062793', 'descriptor_name': 'Occludin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012463', 'descriptor_name': 'Saliva', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012463', 'descriptor_name': 'Saliva', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012469', 'descriptor_name': 'Salivary Glands', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012469', 'descriptor_name': 'Salivary Glands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D014867', 'descriptor_name': 'Water', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1073/pnas.0608384104', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1802728', 'pdf_url': 'https://europepmc.org/articles/pmc1802728?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802728', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17360692', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1802728', 'pdf_url': 'https://europepmc.org/articles/pmc1802728?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.84, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W1511089233', 'https://openalex.org/W1521522718', 'https://openalex.org/W1732737686', 'https://openalex.org/W1918493234', 'https://openalex.org/W1965563432', 'https://openalex.org/W1966505216', 'https://openalex.org/W1971786188', 'https://openalex.org/W1973427303', 'https://openalex.org/W1979547508', 'https://openalex.org/W1999637459', 'https://openalex.org/W2002335276', 'https://openalex.org/W2013567905', 'https://openalex.org/W2025745598', 'https://openalex.org/W2032925493', 'https://openalex.org/W2040334251', 'https://openalex.org/W2042939284', 'https://openalex.org/W2045611996', 'https://openalex.org/W2047922146', 'https://openalex.org/W2048085684', 'https://openalex.org/W2052818458', 'https://openalex.org/W2062248640', 'https://openalex.org/W2064457975', 'https://openalex.org/W2082676696', 'https://openalex.org/W2092800155', 'https://openalex.org/W2093386542', 'https://openalex.org/W2099367536', 'https://openalex.org/W2102527427', 'https://openalex.org/W2104518242', 'https://openalex.org/W2109536209', 'https://openalex.org/W2111937069', 'https://openalex.org/W2114887525', 'https://openalex.org/W2115956096', 'https://openalex.org/W2117979757', 'https://openalex.org/W2120485514', 'https://openalex.org/W2127302126', 'https://openalex.org/W2128984164', 'https://openalex.org/W2130466840', 'https://openalex.org/W2132024007', 'https://openalex.org/W2140669673', 'https://openalex.org/W2150267721', 'https://openalex.org/W2163691419', 'https://openalex.org/W2171894932', 'https://openalex.org/W2226278122', 'https://openalex.org/W2400349087', 'https://openalex.org/W2401647190', 'https://openalex.org/W2405614835', 'https://openalex.org/W280713779', 'https://openalex.org/W3090440650', 'https://openalex.org/W4233435661', 'https://openalex.org/W82441265'], 'related_works': ['https://openalex.org/W4248582800', 'https://openalex.org/W4246433073', 'https://openalex.org/W4237287074', 'https://openalex.org/W3105477738', 'https://openalex.org/W2971617552', 'https://openalex.org/W28798147', 'https://openalex.org/W2707015926', 'https://openalex.org/W2155411113', 'https://openalex.org/W2016300465', 'https://openalex.org/W1998461769'], 'abstract_inverted_index': {'To': [0], 'investigate': [1], 'potential': [2], 'physiological': [3], 'interactions': [4], 'between': [5, 120], 'the': [6, 23, 44, 48, 73, 80, 99, 113, 132, 174, 178, 194, 197, 214], 'transcellular': [7, 25, 49, 116, 225], 'and': [8, 63, 122, 141, 188, 226], 'paracellular': [9, 33, 45, 100, 118, 227], 'pathways': [10], 'of': [11, 19, 35, 54, 76, 82, 98, 115, 134, 138, 177, 185, 196, 216, 229], 'water': [12, 26, 230], 'transport,': [13], 'we': [14, 70], 'asked': [15], 'whether': [16], 'targeted': [17], 'deletion': [18], 'Aquaporin': [20], '5': [21], '(AQP5),': [22], 'major': [24], 'transporter': [27], 'in': [28, 79, 88, 96, 102, 112, 131, 151, 154, 165, 173, 204, 234], 'salivary': [29, 209], 'acinar': [30, 158], 'cells,': [31], 'affected': [32], 'transport': [34, 119, 231], '4-kDa': [36], 'FITC-labeled': [37], 'dextran': [38], '(FITC-D),': [39], 'which': [40], 'is': [41, 85], 'transported': [42, 78], 'through': [43], 'but': [46, 148], 'not': [47], 'route.': [50], 'After': [51], 'i.v.': [52], 'injection': [53], 'FITC-D': [55, 77], 'into': [56], 'either': [57], 'AQP5': [58, 222], 'wild-type': [59], 'or': [60], 'AQP5−/−': [61, 83, 142, 168, 205], 'mice': [62, 84, 103, 144], 'saliva': [64, 81], 'collection': [65], 'for': [66], 'fixed': [67], 'time': [68], 'intervals,': [69], 'show': [71], 'that': [72, 87, 183, 192, 223], 'relative': [74], 'amount': [75], 'half': [86], 'matched': [89], 'AQP5+/+': [90, 140, 208], 'mice,': [91, 169], 'indicating': [92], 'a': [93, 109, 217], '2-fold': [94], 'decrease': [95], 'permeability': [97, 195], 'barrier': [101], 'lacking': [104], 'AQP5.': [105], 'We': [106], 'also': [107], 'found': [108], 'significant': [110], 'difference': [111], 'proportion': [114], 'vs.': [117], 'male': [121, 143], 'female': [123, 155], 'mice.': [124, 156], 'Freeze-fracture': [125], 'electron': [126], 'microscopy': [127], 'revealed': [128, 182], 'an': [129, 171], 'increase': [130], 'number': [133, 153], 'tight': [135, 198], 'junction': [136, 199], 'strands': [137], 'both': [139], 'after': [145], 'pilocarpine': [146], 'stimulation': [147], 'no': [149], 'change': [150], 'strand': [152], 'Average': [157], 'cell': [159], 'volume': [160], 'was': [161], 'increased': [162], 'by': [163], '≈1.4-fold': [164], 'glands': [166], 'from': [167], 'suggesting': [170], 'alteration': [172], 'volume-sensing': [175], 'machinery': [176], 'cell.': [179], 'Western': [180], 'blots': [181], 'expression': [184], 'Claudin-7,': [186], 'Claudin-3,': [187], 'Occludin,': [189], 'critical': [190], 'proteins': [191], 'regulate': [193], 'barrier,': [200], 'were': [201], 'significantly': [202], 'decreased': [203], 'compared': [206], 'with': [207], 'glands.': [210], 'These': [211], 'findings': [212], 'reveal': [213], 'existence': [215], 'gender-influenced': [218], 'molecular': [219], 'mechanism': [220], 'involving': [221], 'allows': [224], 'routes': [228], 'to': [232], 'act': [233], 'conjunction.': [235]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2071488647', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-22T12:30:43.726048', 'created_date': '2016-06-24'}