Publication Information

{'id': 'https://openalex.org/W2071204189', 'doi': 'https://doi.org/10.1159/000363428', 'title': 'Meta-Analyses of the Effect of <b><i>CYP1A1</i></b> and <b><i>CYP2D6</i></b> Polymorphisms on the Risk of Head and Neck Squamous Cell Carcinoma', 'display_name': 'Meta-Analyses of the Effect of <b><i>CYP1A1</i></b> and <b><i>CYP2D6</i></b> Polymorphisms on the Risk of Head and Neck Squamous Cell Carcinoma', 'publication_year': 2014, 'publication_date': '2014-01-01', 'ids': {'openalex': 'https://openalex.org/W2071204189', 'doi': 'https://doi.org/10.1159/000363428', 'mag': '2071204189', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25138301'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000363428', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2769437601', 'display_name': 'Oncology Research and Treatment', 'issn_l': '2296-5270', 'issn': ['2296-5270', '2296-5262'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 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'abstract_inverted_index': {'<b><i>Background:': [0], '</i></b><i>CYP1A1</i>': [1], 'and': [2, 16, 26, 29, 34, 53, 78, 140, 163, 174, 184], '<i>CYP2D6</i>': [3, 27, 54], 'are': [4, 177], 'important': [5], 'genes': [6], 'encoding': [7], 'enzymes': [8], 'involved': [9], 'in': [10, 73, 87, 142, 151], 'the': [11, 22, 30, 49, 57, 74, 88, 117, 137, 172], 'metabolism': [12], 'of': [13, 32, 51, 59, 186], 'toxic': [14], 'chemicals': [15], 'carcinogens.': [17], 'However,': [18], 'inconclusive': [19], 'results': [20, 147], 'for': [21, 116, 134], 'association': [23, 50, 135, 156], 'between': [24, 136, 160], '<i>CYP1A1</i>': [25, 52, 92, 173], 'polymorphisms': [28, 55, 70, 176], 'risk': [31, 58], 'head': [33], 'neck': [35], 'squamous': [36], 'cell': [37], 'carcinoma': [38], '(HNSCC)': [39], 'have': [40], 'been': [41], 'reported.': [42], 'We': [43], 'conducted': [44], 'a': [45], 'meta-analysis': [46], 'to': [47, 181], 'evaluate': [48], 'with': [56, 96, 179], 'HNSCC.': [60, 187], '<b><i>Methods:': [61], '</i></b>A': [62], 'database': [63], 'search': [64], 'yielded': [65], '19': [66], 'relevant': [67], 'studies.': [68], '3': [69], 'were': [71, 85, 148], 'included': [72], 'meta-analysis:': [75], '<i>CYP1A1</i>,': [76], '<i>CYP2D6*4</i>': [77, 138], '<i>CYP2D6*10</i>.': [79], 'Random': [80], 'or': [81], 'fixed': [82], 'effect': [83], 'models': [84], 'used': [86], 'analysis.': [89], '<b><i>Results:': [90], '</i></b>The': [91, 167], 'polymorphism': [93, 139, 162], 'was': [94, 157], 'associated': [95, 178], 'HNSCC': [97, 141, 164], '(for': [98], 'm1m1': [99], 'vs.': [100], 'm1m2:': [101], 'odds': [102], 'ratio': [103], '(OR)': [104], '=': [105, 111, 114, 121, 125, 128], '1.26,': [106], '95%': [107, 123], 'confidence': [108], 'interval': [109], '(CI)': [110], '1.030-1.542,': [112], 'p<sub>heterogeneity</sub>': [113, 127], '0.025;': [115], 'recessive': [118], 'model:': [119], 'OR': [120], '1.316,': [122], 'CI': [124], '1.065-1.625,': [126], '0.001).': [129], 'The': [130], 'analysis': [131], 'showed': [132], 'evidence': [133], 'Asian': [143], 'populations;': [144], 'however,': [145], 'negative': [146], 'also': [149, 158], 'observed': [150, 159], 'other': [152], 'models.': [153], 'A': [154], 'significant': [155], '<i>CYP2D6*10</i>': [161], 'risk.': [165], '<b><i>Conclusions:': [166], 'current': [168], 'study': [169], 'demonstrates': [170], 'that': [171], 'CYP2D6': [175], 'susceptibility': [180], 'both': [182], 'development': [183], 'progression': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2071204189', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}], 'updated_date': '2025-01-08T10:10:35.123455', 'created_date': '2016-06-24'}