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[14, 38, 118], 'damage,': [15], 'and': [16, 40, 117, 122, 139, 184, 196, 204], 'serves': [17], 'as': [18, 61], 'a': [19, 85, 126, 167], 'warning': [20], 'signal': [21], 'to': [22, 67, 130, 199, 212], 'enhance': [23], 'inflammatory': [25], 'response.': [26], 'Acute': [27], 'liver': [28, 64, 99, 158, 180, 218], 'injury': [29, 65], 'one': [31], 'of': [32, 71, 89, 105, 190], 'diseases': [34], 'that': [35, 163], 'starts': [36], 'with': [37, 42, 209], 'damage': [39, 183], 'ends': [41], 'systemic': [43], 'inflammation.': [44], 'We': [45], 'used': [46], 'd': [47, 51, 90, 149, 171, 191], '‐(+)‐galactosamine': [48], 'hydrochloride': [49], '‐': [52, 91, 150, 172, 192], 'G': [53, 92, 151, 173, 193], 'al': [54, 93, 152, 174, 194], 'N': [55, 94, 153, 175, 195], ')/lipopolysaccharide': [56], 'LPS': [58, 96, 155, 177, 197], ')‐treated': [59], 'mice': [60, 147], 'an': [62], 'acute': [63, 98, 157, 179, 217], 'model': [66], 'explore': [68], 'functions': [70], 'in': [74, 145, 170, 216], 'more': [75], 'detail.': [76], 'at': [84], 'very': [86], 'early': [87, 200], 'stage': [88], '/': [95, 154, 176], '‐induced': [97, 156, 178], 'injury.': [100, 181], 'It': [101], 'upregulates': [102], 'expression': [104], 'tumor': [106], 'necrosis': [107, 186], 'factor‐α': [108], 'TNF': [110, 120, 140, 210], '‐α),': [111], 'interleukin‐6,': [112], 'inducible': [113], 'nitric': [114], 'oxide': [115], 'synthase,': [116], 'factor.': [119], '‐α': [121, 141, 211], 'form': [125], 'positive': [127], 'feedback': [128], 'loop': [129], 'amplify': [131], 'downstream': [133], 'signals.': [134], 'mAbs': [135], 'against': [136], 'have': [142], 'synergistic': [143], 'effects': [144], 'protecting': [146], 'from': [148], 'failure.': [159, 219], 'The': [160], 'results': [161], 'suggest': [162], 'key': [168], 'mediator': [169], 'Tissue': [182], 'cell': [185], 'shortly': [187], 'administration': [189], 'lead': [198], 'release,': [203], 'acts': [207], 'synergistically': [208], 'promote': [213], 'pathological': [214], 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