Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2070423606', 'doi': 'https://doi.org/10.1016/j.cbi.2015.02.021', 'title': 'Rutin ameliorates cyclophosphamide induced oxidative stress and inflammation in Wistar rats: Role of NFκB/MAPK pathway', 'display_name': 'Rutin ameliorates cyclophosphamide induced oxidative stress and inflammation in Wistar rats: Role of NFκB/MAPK pathway', 'publication_year': 2015, 'publication_date': '2015-03-06', 'ids': {'openalex': 'https://openalex.org/W2070423606', 'doi': 'https://doi.org/10.1016/j.cbi.2015.02.021', 'mag': '2070423606', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25753322'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cbi.2015.02.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S34460812', 'display_name': 'Chemico-Biological Interactions', 'issn_l': '0009-2797', 'issn': ['0009-2797', '1872-7786'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5014034475', 'display_name': 'Sana Nafees', 'orcid': 'https://orcid.org/0000-0002-2898-5046'}, 'institutions': [{'id': 'https://openalex.org/I19716509', 'display_name': 'Jamia Hamdard', 'ror': 'https://ror.org/03dwxvb85', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I19716509']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sana Nafees', 'raw_affiliation_strings': ['Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.'], 'affiliations': [{'raw_affiliation_string': 'Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.', 'institution_ids': ['https://openalex.org/I19716509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057043467', 'display_name': 'Summya Rashid', 'orcid': 'https://orcid.org/0000-0002-7692-6059'}, 'institutions': [{'id': 'https://openalex.org/I19716509', 'display_name': 'Jamia Hamdard', 'ror': 'https://ror.org/03dwxvb85', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I19716509']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Summya Rashid', 'raw_affiliation_strings': ['Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.'], 'affiliations': [{'raw_affiliation_string': 'Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.', 'institution_ids': ['https://openalex.org/I19716509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043216402', 'display_name': 'Nemat Ali', 'orcid': 'https://orcid.org/0000-0001-6525-4202'}, 'institutions': [{'id': 'https://openalex.org/I19716509', 'display_name': 'Jamia Hamdard', 'ror': 'https://ror.org/03dwxvb85', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I19716509']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Nemat Ali', 'raw_affiliation_strings': ['Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.'], 'affiliations': [{'raw_affiliation_string': 'Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.', 'institution_ids': ['https://openalex.org/I19716509']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111565934', 'display_name': 'Syed Kazim Hasan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I19716509', 'display_name': 'Jamia Hamdard', 'ror': 'https://ror.org/03dwxvb85', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I19716509']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Syed Kazim Hasan', 'raw_affiliation_strings': ['Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.'], 'affiliations': [{'raw_affiliation_string': 'Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.', 'institution_ids': ['https://openalex.org/I19716509']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074558908', 'display_name': 'Sarwat Sultana', 'orcid': 'https://orcid.org/0000-0002-5748-0741'}, 'institutions': [{'id': 'https://openalex.org/I19716509', 'display_name': 'Jamia Hamdard', 'ror': 'https://ror.org/03dwxvb85', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I19716509']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Sarwat Sultana', 'raw_affiliation_strings': ['Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.'], 'affiliations': [{'raw_affiliation_string': 'Molecular Carcinogenesis and Chemoprevention Division, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India.', 'institution_ids': ['https://openalex.org/I19716509']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3410, 'currency': 'USD', 'value_usd': 3410, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 12.732, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 228, 'citation_normalized_percentile': {'value': 0.999932, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '231', 'issue': None, 'first_page': '98', 'last_page': '107'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12429', 'display_name': 'Chemotherapy-induced organ toxicity mitigation', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12429', 'display_name': 'Chemotherapy-induced organ toxicity mitigation', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11332', 'display_name': 'Genomics, phytochemicals, and oxidative stress', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12750', 'display_name': 'Nigella sativa pharmacological applications', 'score': 0.988, 'subfield': {'id': 'https://openalex.org/subfields/2707', 'display_name': 'Complementary and alternative medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2775963812', 'wikidata': 'https://www.wikidata.org/wiki/Q407857', 'display_name': 'Rutin', 'level': 3, 'score': 0.9700695}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.8294908}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.7540188}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.59654427}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.57323754}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.52215576}, {'id': 'https://openalex.org/C57074206', 'wikidata': 'https://www.wikidata.org/wiki/Q14197552', 'display_name': 'MAPK/ERK pathway', 'level': 3, 'score': 0.4936839}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.4896317}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.27948576}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.20574144}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.18223119}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.14250061}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018906', 'descriptor_name': 'Antineoplastic Agents, Alkylating', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D003520', 'descriptor_name': 'Cyclophosphamide', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D020011', 'descriptor_name': 'Protective Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D012431', 'descriptor_name': 'Rutin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018906', 'descriptor_name': 'Antineoplastic Agents, Alkylating', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D056486', 'descriptor_name': 'Chemical and Drug Induced Liver Injury', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D003520', 'descriptor_name': 'Cyclophosphamide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020011', 'descriptor_name': 'Protective Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012431', 'descriptor_name': 'Rutin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cbi.2015.02.021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S34460812', 'display_name': 'Chemico-Biological Interactions', 'issn_l': '0009-2797', 'issn': ['0009-2797', '1872-7786'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25753322', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320767', 'funder_display_name': 'University Grants Commission', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 65, 'referenced_works': ['https://openalex.org/W1518603122', 'https://openalex.org/W1534551308', 'https://openalex.org/W1545899030', 'https://openalex.org/W1608114173', 'https://openalex.org/W1761055895', 'https://openalex.org/W1775749144', 'https://openalex.org/W1903687988', 'https://openalex.org/W1934075708', 'https://openalex.org/W1966571530', 'https://openalex.org/W1967291007', 'https://openalex.org/W1969191668', 'https://openalex.org/W1969480665', 'https://openalex.org/W1971014175', 'https://openalex.org/W1976777085', 'https://openalex.org/W1978258343', 'https://openalex.org/W1978517018', 'https://openalex.org/W1980875818', 'https://openalex.org/W1984498737', 'https://openalex.org/W1986172676', 'https://openalex.org/W1997854782', 'https://openalex.org/W1999925834', 'https://openalex.org/W2004624647', 'https://openalex.org/W2005891669', 'https://openalex.org/W2011138675', 'https://openalex.org/W2012580169', 'https://openalex.org/W2015242961', 'https://openalex.org/W2018263823', 'https://openalex.org/W2024868305', 'https://openalex.org/W2028188178', 'https://openalex.org/W2043494185', 'https://openalex.org/W2045786482', 'https://openalex.org/W2050785940', 'https://openalex.org/W2053239100', 'https://openalex.org/W2053469546', 'https://openalex.org/W2054794305', 'https://openalex.org/W2058118671', 'https://openalex.org/W2058511469', 'https://openalex.org/W2058714321', 'https://openalex.org/W2062010118', 'https://openalex.org/W2065990455', 'https://openalex.org/W2073092594', 'https://openalex.org/W2077315330', 'https://openalex.org/W2079098491', 'https://openalex.org/W2079846604', 'https://openalex.org/W2081130105', 'https://openalex.org/W2081409036', 'https://openalex.org/W2088619566', 'https://openalex.org/W2090602346', 'https://openalex.org/W2090703365', 'https://openalex.org/W2091403015', 'https://openalex.org/W2091446008', 'https://openalex.org/W2094156327', 'https://openalex.org/W2108215738', 'https://openalex.org/W2122057254', 'https://openalex.org/W2135066195', 'https://openalex.org/W2138330152', 'https://openalex.org/W2154108142', 'https://openalex.org/W2164200094', 'https://openalex.org/W2165091126', 'https://openalex.org/W2187589089', 'https://openalex.org/W2263023695', 'https://openalex.org/W2331881627', 'https://openalex.org/W2397808575', 'https://openalex.org/W3139912448', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4361002699', 'https://openalex.org/W4249557888', 'https://openalex.org/W3195118567', 'https://openalex.org/W3091328398', 'https://openalex.org/W2791181644', 'https://openalex.org/W2385227795', 'https://openalex.org/W2382512754', 'https://openalex.org/W2086590465', 'https://openalex.org/W2041265148', 'https://openalex.org/W2012125107'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2070423606', 'counts_by_year': [{'year': 2024, 'cited_by_count': 28}, {'year': 2023, 'cited_by_count': 26}, {'year': 2022, 'cited_by_count': 32}, {'year': 2021, 'cited_by_count': 33}, {'year': 2020, 'cited_by_count': 32}, {'year': 2019, 'cited_by_count': 21}, {'year': 2018, 'cited_by_count': 22}, {'year': 2017, 'cited_by_count': 16}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 8}], 'updated_date': '2025-01-20T21:42:41.034724', 'created_date': '2016-06-24'}