Publication Information

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1200, 1413, 2374, 4266, 4286], 'is': [4, 58, 77, 138, 192, 211, 330, 375, 727, 993, 1132, 1453], 'catalyzed': [5, 139, 396], 'by': [6, 140, 397, 973, 1618, 1631, 1648, 1683, 1735, 1766, 1852, 2082, 2096, 2215, 2235, 2242, 2266, 2365, 2380, 2431, 2435, 2460, 2493, 2498, 2570, 2585, 2647, 2851, 2898, 3397, 3470, 3474, 3479, 3547, 3553, 3580, 3729, 3751, 3812, 3941, 3973, 4343], 'two': [7, 124, 141, 258, 453, 948, 3300], 'known': [8, 142], 'acyl-CoA:diacylglycerol': [9, 143, 299, 398], 'acyltransferase': [10, 144, 399, 732, 790], '(DGAT)': [11, 145, 400], 'enzymes.': [12, 146], 'Although': [13, 147, 3976], 'they': [14, 148], 'catalyze': [15, 149, 707], 'the': [16, 107, 115, 120, 123, 150, 241, 249, 254, 257, 271, 369, 543, 730, 944, 961, 988, 994, 1119, 1137, 1172, 1380, 1386, 1434, 1454, 1458, 1470, 1490, 1569, 1659, 1725, 1730, 1750, 1811, 1816, 1820, 1853, 1859, 1936, 1993, 2000, 2032, 2039, 2163, 2219, 2244, 2267, 2420, 2425, 2454, 2461, 2489, 2572, 2704, 2715, 2901, 3049, 3378, 3442, 3480, 3486, 3505, 3581, 3601, 3619, 3650, 3662, 3718, 3768, 3780, 3824, 3872, 3954, 4002, 4097, 4203, 4214, 4238, 4244, 4248, 4278, 4297], 'same': [17, 151, 1821], 'biochemical': [18, 152], 'reaction,': [19, 153], 'these': [20, 154, 3528], 'enzymes': [21, 125, 155, 259, 401, 640, 791, 953, 1427, 4207], 'share': [22, 156, 719], 'no': [23, 157, 4094], 'sequence': [24, 158, 724], 'homology,': [25, 159], 'and': [26, 48, 76, 86, 100, 160, 182, 210, 220, 234, 317, 328, 385, 427, 457, 537, 563, 711, 735, 965, 979, 1002, 1104, 1109, 1177, 1197, 1313, 1320, 1409, 1441, 1465, 1475, 1481, 1507, 1521, 1568, 1583, 1596, 1614, 1695, 1744, 1776, 1842, 1878, 1888, 1919, 1922, 1933, 1999, 2015, 2031, 2050, 2062, 2078, 2092, 2169, 2182, 2213, 2253, 2257, 2271, 2312, 2332, 2359, 2361, 2372, 2375, 2427, 2443, 2565, 2583, 2609, 2677, 2681, 2694, 2706, 2734, 2792, 2807, 2838, 2879, 2896, 2900, 2907, 2928, 2932, 2940, 2950, 2953, 2964, 2972, 2983, 3115, 3127, 3140, 3163, 3169, 3182, 3188, 3216, 3223, 3236, 3253, 3312, 3361, 3364, 3372, 3380, 3409, 3430, 3444, 3509, 3521, 3560, 3565, 3652, 3669, 3686, 3743, 3765, 3774, 3814, 3819, 3869, 3928, 3981, 3994, 4033, 4101, 4219, 4225, 4230, 4254, 4284, 4319, 4334, 4358], 'their': [27, 161, 704, 1417, 4306], 'relative': [28, 162, 4171], 'functions': [29, 163, 962, 1174], 'are': [30, 84, 164, 218, 270, 381, 539, 552, 641, 738, 1107, 1115, 1195, 1270, 1396, 1407, 1414, 1957, 3455, 3693, 4130], 'poorly': [31, 165], 'understood.': [32, 166], 'Gene': [33, 167, 1865], 'knockout': [34, 168, 1186], 'studies': [35, 169, 974], 'in': [36, 46, 53, 72, 95, 106, 130, 170, 180, 187, 206, 229, 240, 264, 277, 285, 318, 393, 549, 554, 665, 666, 740, 967, 975, 1004, 1092, 1179, 1188, 1201, 1379, 1394, 1404, 1416, 1429, 1438, 1463, 1497, 1511, 1598, 1671, 1754, 1761, 1831, 1959, 1981, 2006, 2010, 2047, 2072, 2114, 2162, 2210, 2298, 2304, 2307, 2320, 2424, 2453, 2532, 2537, 2642, 2721, 2727, 2779, 2800, 2812, 2833, 2840, 2886, 2916, 2919, 2923, 2938, 2948, 2980, 2990, 3002, 3022, 3038, 3048, 3110, 3118, 3178, 3214, 3219, 3238, 3242, 3297, 3366, 3501, 3511, 3524, 3554, 3563, 3570, 3587, 3592, 3595, 3608, 3611, 3623, 3666, 3671, 3696, 3725, 3741, 3759, 3779, 3816, 3825, 3838, 3841, 3850, 3853, 3861, 3866, 3924, 3933, 3953, 4005, 4065, 4096, 4110, 4157, 4167, 4197, 4208, 4221, 4237, 4247, 4264, 4274, 4277, 4324, 4332, 4345, 4356], 'mice': [37, 83, 171, 217, 1269, 1406, 1464, 1723, 1758, 1769, 1779, 1785, 1814, 1825, 2068, 2913, 3211, 3294, 3311, 3313, 3386, 3410, 3716, 3726, 3748, 3930, 3978, 3987, 4007, 4015, 4060, 4162, 4327], 'have': [38, 172, 459, 658, 954, 970, 984, 1198], 'revealed': [39, 173], 'that': [40, 66, 122, 174, 200, 256, 371, 551, 718, 986, 1113, 1129, 1373, 1424, 1451, 1786, 3314, 3644, 3692, 3771, 3881, 4008, 4105, 4270], 'DGAT1': [41, 109, 175, 243, 456, 536, 646, 710, 726, 964, 1176, 1192, 1374, 1389, 1474, 1520, 1613, 3508, 3519, 3533, 3884, 4220, 4233], 'contributes': [42, 176, 3648], 'to': [43, 112, 177, 246, 315, 336, 706, 714, 729, 999, 1272, 1318, 1573, 1605, 1710, 1721, 1807, 1947, 2237, 2259, 2692, 2703, 3171, 3192, 3305, 3413, 3649, 3682, 3709, 4172, 4282], 'triglyceride': [44, 74, 132, 178, 208, 266, 373, 555, 968, 1000, 1093, 1130, 1181, 1392, 1402, 1439, 1461, 2168, 2906, 3513, 3577, 3586, 3603, 3621, 3667], 'tissues': [47, 181, 320, 550, 1872, 2042, 2945, 3761, 3925], 'plays': [49, 68, 183, 202, 1088, 1375], 'an': [50, 184, 366, 1376, 1624, 3268, 4261], 'important': [51, 185, 1377], 'role': [52, 71, 186, 205, 1091, 1378, 1435, 3663, 4204], 'regulating': [54, 188], 'energy': [55, 98, 189, 232, 276, 1280, 1383, 1430, 1442, 4309], 'metabolism': [56, 99, 190, 233, 969, 1393], 'but': [57, 191, 3638], 'not': [59, 193, 1116, 1397, 4182, 4193], 'essential': [60, 194, 1117, 1133], 'for': [61, 79, 97, 114, 195, 213, 231, 248, 452, 1118, 1134, 1457, 1565, 1759, 1954, 2018, 2102, 2113, 2309, 2322, 2548, 2567, 2684, 2739, 2797, 3051, 3226, 3244, 3250, 3945, 4010, 4081, 4308], 'life.': [62, 196], 'Here': [63, 197], 'we': [64, 198, 1183, 1444, 3515, 3673, 4212, 4304], 'show': [65, 199], 'DGAT2': [67, 201, 538, 653, 712, 785, 966, 1178, 1437, 1452, 1522, 1615, 1661, 3497, 3510, 3522, 3540, 3645, 3665, 3697, 3738, 3942, 4218, 4240, 4271], 'a': [69, 203, 394, 1083, 1089, 1125, 1276, 1512, 1574, 1685, 1696, 1745, 1832, 1844, 1982, 2086, 2195, 2247, 2291, 2337, 2538, 2542, 2590, 2600, 2610, 2746, 2841, 3111, 3119, 3143, 3200, 3338, 3394, 3399, 3783, 3879, 4062, 4122, 4198, 4253, 4275], 'fundamental': [70, 204], 'mammalian': [73, 131, 207, 265, 1180], 'required': [78, 212], 'survival.': [80, 214], 'DGAT2-deficient': [81, 215, 1642, 3659], '(Dgat2-/-)': [82, 216], 'lipopenic': [85, 219], 'die': [87, 221], 'soon': [88, 222], 'after': [89, 223, 2649, 3436, 3998], 'birth,': [90, 224], 'apparently': [91, 225], 'from': [92, 101, 226, 235, 383, 956, 1489, 1650, 1658, 1675, 1810, 1871, 2038, 2066, 2204, 2354, 2362, 2439, 2785, 2894, 3309, 3358, 3441, 3790, 3948, 3983], 'profound': [93, 227], 'reductions': [94, 228], 'substrates': [96, 230, 4307], 'impaired': [102, 236], 'permeability': [103, 237], 'barrier': [104, 238, 1834], 'function': [105, 239], 'skin.': [108, 242, 3404], 'was': [110, 244, 1553, 1571, 1669, 1708, 1733, 1869, 1931, 1991, 1996, 2002, 2026, 2034, 2057, 2111, 2264, 2342, 2429, 2847, 2877, 2909, 3197, 3265, 3335, 3375, 3417, 3439, 3448, 3493, 3545, 3589, 3605, 3680, 3707, 3727, 3749, 3762, 3810, 3864, 4093, 4235, 4241], 'unable': [111, 245], 'compensate': [113, 247], 'absence': [116, 250], 'DGAT2,': [118, 252, 458, 992, 1550], 'supporting': [119, 253], 'hypothesis': [121, 255], 'play': [126, 260], 'fundamentally': [127, 261], 'different': [128, 262, 715, 949, 3298, 3301, 3321, 3324], 'roles': [129, 263, 3506], 'metabolism.': [133, 267, 1384, 4310], 'Triglycerides': [268, 380], '(triacylglycerols)': [269], 'major': [272, 995], 'storage': [273, 1003, 3653, 3670], 'form': [274], 'eukaryotic': [278, 1533], 'organisms.': [279], 'However,': [280, 702, 1124, 1385, 3576], 'excessive': [281], 'deposition': [282], 'white': [286, 295], 'adipose': [287, 296, 303, 2064, 2942], 'tissue': [288, 333, 2065, 2088, 2208, 2943, 3017, 3106, 4265], '(WAT)': [289], '1The': [290], 'abbreviations': [291], 'used': [292, 1184, 1709, 1720, 2112, 3304, 3708], 'are:': [293], 'WAT,': [294, 559], 'tissue;': [297, 304], 'DGAT,': [298], 'acyltransferase;': [300], 'BAT,': [301], 'brown': [302, 2063, 2941], 'PBS,': [305, 2331], 'phosphate-buffered': [306, 2011], 'saline;': [307], 'C/EPBα,': [308], 'CCAAT/enhancer-binding': [309], 'protein;': [310], 'E,': [311], 'embryonic': [312, 1714, 3711, 4069, 4210], 'day.': [313], 'leads': [314], 'obesity': [316, 1274], 'non-adipose': [319], '(such': [321], 'as': [322, 337, 558, 1823, 2120, 2290, 2383, 2496, 2613, 2849, 3450, 3457, 3551], 'pancreatic': [323], 'β': [324], 'cells,': [325, 1716, 2300, 3567, 3618, 3632], 'skeletal': [326], 'muscle,': [327], 'liver)': [329], 'associated': [331], 'with': [332, 542, 788, 1502, 1516, 1523, 1555, 1623, 1633, 1655, 1742, 1783, 1826, 1886, 1935, 2155, 2176, 2194, 2218, 2288, 2315, 2330, 2336, 2344, 2449, 2559, 2599, 2745, 2820, 2853, 2930, 2955, 2986, 3034, 3104, 3134, 3142, 3159, 3165, 3184, 3199, 3234, 3248, 3267, 3337, 3419, 3701, 3803, 4133], 'dysfunction': [334], 'referred': [335], 'lipotoxicity': [338], '(1Unger': [339], 'R.H.': [340, 351, 1222, 1253, 1299, 1339, 2402], 'Zhou': [341, 506, 610, 673, 798, 2126, 3890], 'Y.T.': [342], 'Diabetes.': [343], '2001;': [344, 522, 626, 689, 2142, 2519, 2632, 3906], '50:': [345], 'S118-S121Crossref': [346], 'PubMed': [347, 360, 412, 497, 530, 601, 634, 697, 779, 813, 834, 858, 894, 916, 937, 1027, 1041, 1075, 1165, 1231, 1263, 1308, 1349, 1365, 1802, 2150, 2283, 2412, 2482, 2522, 2635, 2663, 2772, 3071, 3097, 3290, 3914, 4149], 'Google': [348, 363, 415, 500, 533, 604, 637, 700, 782, 816, 837, 861, 897, 919, 940, 1030, 1044, 1078, 1168, 1234, 1266, 1311, 1352, 1368, 1805, 2153, 2286, 2415, 2483, 2525, 2638, 2666, 2775, 3074, 3100, 3291, 3917, 4152], 'Scholar,': [349, 416, 432, 501, 605, 817, 838, 862, 898, 920, 1031, 1045, 1235, 1353, 3075], '2Unger': [350], 'Orci': [352], 'L.': [353, 1047], 'Biochim.': [354, 2277], 'Biophys.': [355, 2278], 'Acta.': [356, 2279], '2002;': [357, 810, 1019, 1038, 1067, 1260, 1346, 1362, 2409, 4141], '1585:': [358], '202-212Crossref': [359], 'Scopus': [361, 413, 498, 531, 602, 635, 698, 780, 814, 835, 859, 895, 917, 938, 1028, 1042, 1076, 1166, 1232, 1264, 1309, 1350, 1366, 1803, 2151, 2284, 2413, 2523, 2636, 2664, 2773, 3072, 3098, 3915, 4150], '(307)': [362], 'Scholar).': [364, 449, 534, 638, 701, 941, 1079, 1169, 1267, 1369, 2416, 2484, 2526, 2639, 2667, 2776, 3101, 3292], 'Therefore,': [365], 'understanding': [367], 'processes': [370], 'mediate': [372], 'significant': [377, 1410, 1467], 'biomedical': [378], 'importance.': [379], 'synthesized': [382], 'diacylglycerol': [384], 'activated': [386], 'forms': [387], 'fatty': [389, 661, 2171, 2553, 4317], 'acids': [390, 3799], '(fatty': [391], 'acyl-CoAs)': [392], 'reaction': [395], '(3Bell': [402], 'R.M.': [403, 2507, 2620], 'Coleman': [404], 'R.A.': [405], 'Annu.': [406], 'Rev.': [407], 'Biochem.': [408, 2658], '1980;': [409], '49:': [410], '459-487Crossref': [411], '(457)': [414], '4Brindley': [417], 'D.N.': [418], 'Vance': [419, 421], 'D.E.': [420], 'J.E.': [422], 'Biochemistry': [423], 'Lipids,': [425], 'Lipoproteins': [426], 'Membranes.': [428], 'Elsevier,': [429], 'Amsterdam1991:': [430], '171-203Google': [431], '5Gunstone': [433], 'F.D.': [434], 'Harwood': [435], 'J.L.': [436], 'Padley': [437], 'F.B.': [438], 'Lipid': [440, 2200, 3282], 'Handbook.': [441], '2nd': [442], 'Ed.': [443], 'Chapman': [444], '&': [445], 'Hall,': [446], 'London1994:': [447], '646-651Google': [448], 'genes': [451, 1956], 'DGAT': [454, 952, 996, 1102, 1455, 2059, 2116, 3548, 3808, 3839, 3862, 3921, 4206], 'enzymes,': [455, 733], 'been': [460, 971], 'identified': [461, 1617], '(6Cases': [462, 566, 744], 'S.': [463, 475, 492, 503, 567, 579, 596, 607, 670, 745, 757, 774, 797, 808, 1063, 1149, 1208, 1285, 2123, 3887], 'Smith': [464, 568, 746, 1238, 1324, 2387], 'S.J.': [465, 505, 569, 609, 672, 747, 795, 1206, 1239, 1283, 1325, 2125, 2388, 3889], 'Zheng': [466, 570, 748], 'Y.-W.': [467, 571, 749], 'Myers': [468, 572, 750], 'H.M.': [469, 573, 751], 'Lear': [470, 574, 752], 'S.R.': [471, 575, 753], 'Sande': [472, 576, 754, 1213, 1290], 'E.': [473, 509, 577, 613, 676, 755, 1055, 1214, 1291, 2129, 3893], 'Novak': [474, 578, 756], 'Collins': [476, 580, 758], 'C.': [477, 581, 759], 'Welch': [478, 582, 760], 'C.B.': [479, 583, 761], 'Lusis': [480, 584, 762], 'A.J.': [481, 585, 763], 'Erickson': [482, 586, 764], 'S.K.': [483, 587, 765], 'Farese': [484, 516, 588, 620, 683, 766, 800, 820, 1223, 1254, 1300, 1340, 1358, 2136, 2403, 3900], 'Jr.,': [485, 517, 589, 621, 684, 767, 801, 821, 1224, 1255, 1301, 1341, 1359, 2137, 2404, 3901], 'R.V.': [486, 518, 590, 622, 685, 768, 802, 822, 1225, 1256, 1302, 1342, 1360, 2138, 2405, 3902], 'Proc.': [487, 591, 769, 803], 'Natl.': [488, 592, 770, 804], 'Acad.': [489, 593, 771, 805], 'Sci.': [490, 594, 772, 806], 'U.': [491, 595, 773, 807, 1051], 'A.': [493, 597, 775, 809, 1053, 1057], '1998;': [494, 598, 776, 1799], '95:': [495, 599, 777], '13018-13023Crossref': [496, 600, 778], '(886)': [499, 603, 781], '7Cases': [502, 606], 'Stone': [504, 608, 671, 794, 2124, 3888], 'P.': [507, 611, 674, 799, 844, 902, 926, 1007, 2127, 3891], 'Yen': [508, 612, 675, 2128, 3892], 'Tow': [510, 614, 677, 1215, 1292, 2130, 3894], 'B.': [511, 615, 678, 1216, 1293, 2131, 3895], 'Lardizabal': [512, 616, 679, 2132, 3896], 'K.D.': [513, 617, 680, 2133, 3897], 'Voelker': [514, 618, 681, 2134, 3898], 'T.': [515, 619, 682, 2135, 3899], 'J.': [519, 623, 686, 823, 840, 842, 847, 868, 872, 883, 900, 905, 924, 930, 1016, 1036, 1064, 1154, 1220, 1257, 1297, 1343, 2139, 2406, 2468, 2473, 2657, 2766, 3062, 3088, 3281, 3903], 'Biol.': [520, 624, 687, 824, 848, 884, 906, 1017, 1065, 1155, 2140, 2474, 3904], 'Chem.': [521, 625, 688, 825, 849, 885, 907, 1018, 1066, 1156, 2141, 2475, 3905], '276:': [523, 627, 690, 2143, 3907], '38870-38876Abstract': [524, 628, 691, 2144, 3908], 'Full': [525, 527, 629, 631, 692, 694, 829, 831, 853, 855, 889, 891, 911, 913, 1022, 1024, 1070, 1072, 1160, 1162, 2145, 2147, 2479, 3068, 3094, 3287, 3909, 3911, 4144, 4146], 'Text': [526, 528, 630, 632, 693, 695, 830, 832, 854, 856, 890, 892, 912, 914, 1023, 1025, 1071, 1073, 1161, 1163, 2146, 2148, 2480, 3069, 3095, 3288, 3910, 3912, 4145, 4147], 'PDF': [529, 633, 696, 833, 857, 893, 915, 1026, 1074, 1164, 2149, 2481, 3070, 3096, 3289, 3913, 4148], '(643)': [532, 636, 699, 2152, 3916], 'Both': [535, 639, 656, 2041], 'ubiquitously': [540], 'expressed,': [541], 'highest': [544, 4236, 4245], 'levels': [545, 1403, 1944, 2191, 2641, 3535, 3541, 3923, 4129, 4216, 4313, 4339, 4353], 'expression': [547, 1534, 1546, 3740, 3846, 4115, 4166, 4215, 4234], 'found': [548, 3865, 3952], 'active': [553], 'synthesis,': [556], 'such': [557], 'small': [560, 2790], 'intestine,': [561], 'liver,': [562], 'mammary': [564], 'gland': [565], 'intrinsic': [642], 'membrane': [643], 'proteins,': [644], 'although': [645], 'has': [647, 654], '6-12': [648], 'putative': [649], 'transmembrane': [650], 'domains,': [651], 'whereas': [652, 784], 'one.': [655], 'also': [657, 1314, 1781, 3636, 4341], 'similarly': [659], 'broad': [660], 'acyl-CoA': [662], 'substrate': [663], 'specificities': [664], 'vitro': [667, 2115, 3555, 3826], 'assays': [668, 2179, 3934], '(7Cases': [669, 2122, 3886], 'despite': [703], 'ability': [705, 4279], 'similar': [708, 3932, 4355], 'reactions,': [709], 'belong': [713], 'gene': [716, 1185, 1732, 1818, 3698], 'families': [717], 'neither': [720], 'DNA': [721, 1654, 1740, 3735], 'nor': [722], 'protein': [723, 1972, 3534, 3788, 4120, 4178], 'similarity.': [725], 'homologous': [728], 'acyl-CoA:cholesterol': [731], 'ACAT1': [734], 'ACAT2,': [736], 'which': [737, 1717, 3557], 'involved': [739], 'cholesterol': [741], 'ester': [742], 'biosynthesis': [743], 'Scholar),': [783, 2154, 4153], 'shares': [786], 'homology': [787], 'acyl-CoA:monoacylglycerol': [789], '(8Yen': [792], 'C.-L.E.': [793, 819], 'Cases': [796, 1207, 1284], '99:': [811], '8512-8517Crossref': [812], '(156)': [815], '9Yen': [818], '2003;': [826, 850, 886, 908, 934, 1157], '278:': [827, 851, 887, 909, 1158], '18532-18537Abstract': [828], '(149)': [836], '10Cao': [839], 'Lockwood': [841], 'Burn': [843, 901, 925], 'Shi': [845, 903, 927], 'Y.': [846, 904, 928], '13860-13866Abstract': [852], '(112)': [860], '11Cheng': [863], 'D.': [864, 1009, 1033], 'Nelson': [865], 'T.C.': [866], 'Chen': [867, 1211, 1288], 'Walker': [869], 'S.G.': [870], 'Wardwell-Swanson': [871], 'Meegalla': [873], 'R.': [874, 876, 3085], 'Taub': [875], 'Billheimer': [877, 1012], 'J.T.': [878, 1013], 'Ramaker': [879], 'M.': [880, 1011, 1059, 1794, 2470], 'Feder': [881], 'J.N.': [882], '13611-13614Abstract': [888], '(123)': [896], '12Cao': [899], '25657-25663Abstract': [910], '(54)': [918], '13Lockwood': [921], 'J.F.': [922], 'Cao': [923], 'Am.': [929], 'Physiol.': [931, 2659], 'Endocrinol.': [932, 4139], 'Metal.': [933], '285:': [935], 'E927-E937Crossref': [936], '(30)': [939], 'This': [942, 1706, 3544, 3705], 'raises': [943], 'question': [945], 'why': [947], 'types': [950], 'emerged': [955], 'convergent': [957], 'evolution.': [958], 'Insights': [959], 'into': [960, 1469, 1532, 1884, 2246, 2789, 2905, 2926, 2969, 3585], 'provided': [972, 2674], 'yeast.': [976, 1123], 'Through': [977], 'deletion': [978], 'overexpression': [980], 'studies,': [981, 2961], 'several': [982], 'groups': [983], 'demonstrated': [985, 3728], 'DGA1,': [987], 'yeast': [989, 1005, 1084, 1139], 'homologue': [990, 1085], 'enzyme': [997], 'contributing': [998], '(14Oelkers': [1006], 'Cromley': [1008], 'Padamsee': [1010], 'Sturley': [1014], 'S.L.': [1015], '277:': [1020, 1068], '8877-8881Abstract': [1021], '(261)': [1029], '15Sorger': [1032], 'Daum': [1034], 'G.': [1035, 3276], 'Bacteriol.': [1037], '184:': [1039], '519-524Crossref': [1040], '(177)': [1043], '16Sandager': [1046], 'Gustavsson': [1048], 'M.H.': [1049], 'Stahl': [1050], 'Dahlqvist': [1052], 'Wiberg': [1054], 'Banas': [1056], 'Lenman': [1058], 'Ronne': [1060], 'H.': [1061, 1153], 'Stymne': [1062], '6478-6482Abstract': [1069], '(411)': [1077], 'In': [1080, 2417, 3527, 3616, 3630], 'contrast,': [1081], 'ARE2,': [1082], 'DGAT1,': [1087, 1549], 'minor': [1090], 'synthesis.': [1094], 'Interestingly,': [1095], 'mutant': [1096], 'Saccharomyces': [1097], 'cerevisiae': [1098], 'strains': [1099], 'devoid': [1100], 'activity': [1103, 2117, 3549, 3646, 3809, 3840, 3863, 3885, 3922], 'lacking': [1105, 1191, 1815], 'viable': [1108, 1196], 'grow': [1110], 'normally,': [1111], 'indicating': [1112, 4104], 'survival': [1120], 'this': [1122, 1762, 3791, 4290], 'recent': [1126], 'study': [1127, 1763], 'showed': [1128, 3770], 'viability': [1135, 2846], 'fission': [1138], 'Schizosaccharomyces': [1140], 'pombe': [1141], '(17Zhang': [1142], 'Q.': [1143], 'Chieu': [1144], 'H.K.': [1145], 'Low': [1146], 'C.P.': [1147], 'Zhang': [1148], 'Heng': [1150], 'C.K.': [1151], 'Yang': [1152], '47145-47155Abstract': [1159], '(108)': [1167], 'To': [1170, 1432, 2293, 2934, 4201, 4295], 'determine': [1171], 'physiological': [1173], 'metabolism,': [1182, 3514], 'approaches': [1187], 'mice.': [1189, 1447, 3676, 4336], 'Mice': [1190, 1828, 3230], '(Dgat1-/-': [1193], 'mice)': [1194], 'reduced': [1199, 3750, 3811, 4342], 'tissues,': [1202, 1418], 'including': [1203, 1419], 'WAT': [1204], '(18Smith': [1205, 1282], 'Jensen': [1209, 1242, 1286, 1328, 2391], 'D.R.': [1210, 1243, 1287, 1329, 2392], 'H.C.': [1212, 1237, 1289, 1323, 1355, 2386], 'Sanan': [1217, 1294], 'D.A.': [1218, 1295], 'Raber': [1219, 1296], 'Eckel': [1221, 1252, 1298, 1338, 2401], 'Nat.': [1226, 1303, 1797], 'Genet.': [1227, 1304, 1798], '2000;': [1228, 1305], '25:': [1229, 1306], '87-90Crossref': [1230, 1307], '(743)': [1233, 1310], '19Chen': [1236], 'Ladha': [1240, 1326, 1356, 2389], 'Z.': [1241, 1327, 1357, 2390], 'Ferreira': [1244, 1330, 2393], 'L.D.': [1245, 1331, 2394], 'Pulawa': [1246, 1332, 2395], 'L.K.': [1247, 1333, 2396], 'McGuire': [1248, 1334, 2397], 'J.G.': [1249, 1335, 2398], 'Pitas': [1250, 1336, 2399], 'R.E.': [1251, 1337, 2400], 'Clin.': [1258, 1344, 2407, 2767], 'Invest.': [1259, 1345, 2408, 2768], '109:': [1261, 1347, 2410], '1049-1055Crossref': [1262, 1348, 2411], '(284)': [1265, 1351, 2414], 'Dgat1-/-': [1268, 1405], 'resistant': [1271], 'diet-induced': [1273], 'through': [1275], 'mechanism': [1277], 'involving': [1278], 'increased': [1279, 1316, 4155], 'expenditure': [1281], 'Scholar)': [1312, 1806, 2287, 3918], 'exhibit': [1315], 'sensitivity': [1317], 'leptin': [1319], 'insulin': [1321], '(19Chen': [1322, 2385], '20Chen': [1354], 'Endocrinology.': [1361], '143:': [1363], '2893-2898Crossref': [1364], '(31)': [1367], 'These': [1370, 1421, 3318, 3641], 'findings': [1371, 1422], 'indicate': [1372, 1450], 'regulation': [1381], 'effects': [1387], 'deficiency': [1390, 4272], 'on': [1391, 1855, 2029, 2226], 'general': [1395], 'profound.': [1398], 'For': [1399, 1540, 1985, 2348, 2959, 3464, 3483], 'example,': [1400], 'plasma': [1401, 2376, 2426, 2440, 3201, 4312], 'normal,': [1408], 'amounts': [1411], 'present': [1415, 3637], 'WAT.': [1420], 'suggest': [1423], 'other': [1425, 2418], 'triglyceride-synthesizing': [1426], 'participate': [1428], 'homeostasis.': [1431], 'understand': [1433], 'homeostasis,': [1443], 'generated': [1445, 1765, 3674], 'Dgat2-/-': [1446, 1757, 1813, 1824, 3362, 3373, 3675, 3747, 3760, 3817, 3867, 3986, 4006, 4014, 4059, 4102, 4160, 4258, 4302, 4326, 4347, 4359], 'Our': [1448], 'results': [1449, 3642, 4273], 'responsible': [1456], 'majority': [1459], 'provide': [1466], 'insights': [1468], 'functional': [1471], 'differences': [1472], 'between': [1473], 'DGAT2.': [1476], 'Generation': [1477, 1640, 3657], 'Stable': [1479], 'DGAT1-': [1480, 3564], 'DGAT2-expressing': [1482], 'Cell': [1483, 1609, 2090, 2845], 'Lines—McArdle': [1484], 'rat': [1485], 'hepatoma': [1486], '(McA-RH7777)': [1487], 'cells': [1488, 1584, 1592, 2301, 2880, 2895, 3573, 3588, 3597, 3613, 3713], 'American': [1491], 'Type': [1492], 'Culture': [1493], 'Collection': [1494], 'were': [1495, 1530, 1593, 1616, 1646, 1718, 1764, 1780, 1829, 1850, 1882, 1945, 2043, 2069, 2094, 2174, 2192, 2202, 2233, 2302, 2326, 2334, 2352, 2378, 2447, 2491, 2530, 2557, 2581, 2645, 2717, 2743, 2783, 2817, 2881, 2891, 2914, 2946, 2967, 2999, 3019, 3108, 3132, 3157, 3176, 3212, 3231, 3258, 3295, 3303, 3356, 3407, 3411, 3468, 3536, 3558, 3635, 3776, 3931, 3951, 3979, 3988, 4034, 4154, 4321, 4340, 4354], 'cultured': [1496, 1597], "Dulbecco's": [1498, 2824, 3367], 'modified': [1499, 2825, 3368], "Eagle's": [1500, 2826, 3369], 'medium': [1501, 1582, 1600, 2863], '10%': [1503, 1508, 2250, 2828], 'fetal': [1504, 2829, 4126, 4293], 'bovine': [1505, 2809, 2830, 2874], 'serum': [1506, 1510, 2810, 2875], 'horse': [1509], '37': [1513, 2022, 2795, 2884], '°C': [1514, 2054, 2547, 2738, 2796, 2885, 2979, 3010], 'incubator': [1515], '5%': [1517, 2887], 'CO2.': [1518], 'Mouse': [1519, 3349, 3415], 'N-terminal': [1524], 'FLAG': [1525], 'epitopes': [1526], '(MGDYKDDDDG,': [1527], 'epitope': [1528], 'underlined)': [1529], 'cloned': [1531], 'vector': [1535, 1547, 1668, 1751, 3679, 3706], 'pCDNA3.1': [1536], '(Invitrogen,': [1537], 'Carlsbad,': [1538], 'CA).': [1539], 'transfections,': [1541], '1': [1542, 1898, 1926, 2859, 3227], 'μg': [1543, 2108], 'pcDNA3.1': [1545], 'containing': [1548, 1578, 1601, 1689, 1700, 2561, 2864, 3124, 3426], 'or': [1551, 2158, 2207, 2240, 3027, 3473, 3490, 4288], 'LacZ': [1552], 'incubated': [1554, 2793, 2882], '3': [1556, 1694, 2533, 3685, 3773], 'μl': [1557, 1899, 1903, 1924], 'FuGENE': [1559], '6': [1560], 'transfection': [1561], 'reagent': [1562], '(Roche': [1563], 'Diagnostics)': [1564], '20': [1566, 2157, 3251, 3830, 3936], 'min,': [1567, 3246, 3252], 'mixture': [1570, 1910, 3828, 3874], 'added': [1572], '60-mm': [1575, 2842], 'culture': [1576, 2843], 'dish': [1577], '2': [1579, 2693, 2857, 3179], 'ml': [1580, 2802, 2822, 2835, 2860], 'at': [1585, 2021, 2052, 2098, 2545, 2736, 2794, 2883, 2977, 3008, 3045, 3152, 3259, 4068, 4227, 4243, 4287], '∼50%': [1586], 'confluence.': [1587], 'After': [1588, 2712, 2856, 3102], '48': [1589], 'h,': [1590, 2858], 'transfected': [1591, 3530], 'split': [1594], '1:4': [1595], 'growth': [1599, 1966, 4056, 4106, 4118, 4176], '600': [1602, 2099], 'μg/ml': [1603, 2317], 'G418': [1604], 'generate': [1606, 1722, 3710], 'G418-resistant': [1607], 'colonies.': [1608], 'lines': [1610], 'stably': [1611, 3529], 'expressing': [1612], 'immunoblotting': [1619], 'cell': [1621, 3531], 'lysates': [1622], 'anti-FLAG': [1625], 'M2': [1626], 'monoclonal': [1627], 'antibody': [1628], '(Sigma)': [1629, 2806], 'followed': [1630, 3478], 'detection': [1632, 1940], 'SuperSignal': [1634], 'West': [1635], 'Pico': [1636], 'Detection': [1637], 'kit': [1638, 2178, 3204], '(Pierce).': [1639], 'Mice—DGAT2': [1643], 'genomic': [1644, 1653, 1739, 3734], 'fragments': [1645], 'amplified': [1647], 'PCR': [1649, 1896, 1930, 1939, 1963], '129/SvJae': [1651, 1713], 'mouse': [1652, 1660, 2356, 3518, 3733, 4209], 'primers': [1656], 'derived': [1657], 'cDNA': [1662, 1885], 'sequence.': [1663], 'A': [1664, 3677, 3787], 'replacement': [1665], 'type': [1666], 'targeting': [1667], 'constructed': [1670], 'pNTKloxP': [1672], '(a': [1673], 'gift': [1674], 'Joachim': [1676], 'Herz,': [1677], 'University': [1678, 1860], 'Texas,': [1680], 'Dallas,': [1681], 'TX)': [1682], 'subcloning': [1684], '∼1-kb': [1686], 'short': [1687], 'arm': [1688, 1699], 'sequences': [1690, 1701, 1752], 'upstream': [1691, 1748], 'exon': [1693, 1704], '∼5-kb': [1697], 'long': [1698], 'downstream': [1702], '4.': [1705], 'construct': [1707], 'produce': [1711], 'DGAT2-targeted': [1712], 'stem': [1715, 3712], 'then': [1719, 2027, 2313, 2327, 2892, 3000, 3020, 3232, 3254], 'carrying': [1724, 3717], 'mutation.': [1726], 'disruption': [1728, 3722], 'Dgat2': [1731, 3724, 3757], 'confirmed': [1734], 'Southern': [1736, 3730], 'blotting': [1737, 3731], 'digested': [1741, 3158], 'EcoRI': [1743], 'probe': [1746], 'located': [1747], '(described': [1753], 'Fig.': [1755], '2a).': [1756, 3704], 'use': [1760], 'intercrossing': [1767], 'Dgat2+/-': [1768, 1778, 3929, 3977, 4333], 'mixed': [1771], 'genetic': [1772], 'background': [1773], '(50%': [1774], 'C57BL/6J': [1775], '129/SvJae).': [1777], 'crossed': [1782], 'transgenic': [1784], 'constitutively': [1787], 'express': [1788], 'Cre': [1789], 'recombinase': [1790], '(21Meyers': [1791], 'E.N.': [1792], 'Lewandoski': [1793], 'Martin': [1795], 'G.R.': [1796], '18:': [1800], '136-141Crossref': [1801], '(889)': [1804], 'remove': [1808], 'neo': [1809, 1817, 3702], 'allele.': [1812, 3720], 'had': [1819, 3320, 4061, 4260], 'phenotype': [1822], 'neo.': [1827], 'housed': [1830, 3296], 'pathogen-free': [1833], 'facility': [1835], '(12': [1836], 'h': [1837, 1839, 3997], 'light/12': [1838], 'dark': [1840, 3050], 'cycle)': [1841], 'fed': [1843], 'standard': [1845], 'chow': [1846, 3416], 'diet.': [1847], 'All': [1848, 3256], 'experiments': [1849], 'approved': [1851], 'Committee': [1854], 'Animal': [1856], 'Research': [1857], 'California,': [1862], 'San': [1863], 'Francisco.': [1864], 'Expression': [1866, 1943], 'Analyses—Total': [1867], 'RNA': [1868, 2056], 'extracted': [1870, 2203, 2353, 2448, 2558, 2893], '(RNA': [1873], 'STAT,': [1874], 'Tel-Test,': [1875], 'Friendswood,': [1876], 'TX),': [1877], 'samples': [1879, 2966, 3107], '(1': [1880], 'μg)': [1881], 'reverse-transcribed': [1883], 'oligo(dT)12-18': [1887], 'Superscript': [1889], 'II': [1890], 'reverse': [1891, 1920], 'transcriptase': [1892], '(Invitrogen).': [1893], 'Each': [1894], '30-μl': [1895], 'contained': [1897, 3829, 3875], 'cDNA,': [1901], '15': [1902, 2740, 2798], '2×': [1905], 'QuantiTect': [1906], 'SYBR': [1907], 'green': [1908], 'master': [1909], '(Qiagen,': [1911], 'Valencia,': [1912], 'CA),': [1913], '10': [1914, 2007, 2083, 2821, 2865, 3245], 'pmol': [1915], 'each': [1916, 3016], 'forward': [1918], 'primer,': [1921], '0.5': [1923, 2870], 'μm': [1927], 'fluorescein.': [1928], 'Real-time': [1929], 'performed': [1932, 2119], 'analyzed': [1934, 2379], 'iCycler': [1937], 'real-time': [1938], 'system': [1941, 2221], '(Bio-Rad).': [1942], 'normalized': [1946], '18': [1948], 'S': [1949], 'ribosomal': [1950], 'RNA.': [1951], 'Primer': [1952], 'pairs': [1953], 'specific': [1955], 'listed': [1958], 'Table': [1960], 'I.Table': [1961], 'IReal-time': [1962], 'primer': [1964], 'sequencesGeneSenseAntisenseDGAT-25′-AGTGGCAATGCTATCATCATCGT-3′5′-AAGGAATAAGTGGGAACCAGATCA-3′DGAT-15′-TTCCGCCTCTGGGCATT-3′5′-AGAATCGGCCCACAATCCA-3′UCP-15′-ACACCTGCCTCTCTCGGAAA-3′5′-TAGGCTGCCCAATGAACACT-3′Insulin-like': [1965], 'factor-binding': [1967, 4119, 4177], 'protein5′-TGGACAGCTTCCACCTGATG-3′5′-TTTCTTGAGGTCGGCGATCT-3′18': [1968], 'S5′-AGTCCCTGCCCTTTGTACACA-3′5′-GATCCGAGGGCCTCACTAAAC-3′Phosphoenolpyruvate': [1969], 'carboxykinase5′-CCACAGCTGCTGCAGAACA-3′5′-GAAGGGTCGCATGGCAAA-3′Glucose-6-phosphatase5′-CCATGCAAAGGACTAGGAACAA-3′5′-TACCAGGGCCGATGTCAAC-3′Fructose-1,6-bisphosphatase5′-TGGCAGCCGGGTATGC-3′5′-TCCATGGCAAGGACCAACA-3′Sterol': [1970], 'regulatory-binding': [1971], '1c5′-GGCCCGGGAAGTCACTGT-3′5′-GGAGCCATGGATTGCACATT-3′Acetyl-CoA': [1973], 'carboxylase-15′-GAATCCTCATTGGCTTACGATGAG-3′5′-CAATGGCCCGGCATGT-3′Fatty': [1974], 'acid': [1975, 2172, 2224, 2256, 2554, 2578, 2700, 2709, 4184, 4186], 'synthase5′-GCTGCGGAAACTTCAGGAAAT-3′5′-AGAGACGTGTCACTCCTGGACTT-3′Stearoyl-CoA': [1976], 'desaturase': [1977, 4188, 4190], '15′-CCTTCCCCTTCGACTACTCTG-3′5′-GCCATGCAGTCGATGAAGAA-3′': [1978], 'Open': [1979, 4195], 'table': [1980, 4196], 'new': [1983, 4199], 'tab': [1984, 4200], 'skin': [1986, 1990, 2025, 2360, 2643, 2962, 3316, 3352, 3374], 'analysis,': [1987], 'full': [1988], 'thickness': [1989], 'removed,': [1992], 'subcutaneous': [1994], 'fat': [1995], 'scraped': [1997], 'away,': [1998], 'sample': [2001, 3018], 'immersed': [2003], 'dermis-side': [2004], 'down': [2005], 'mm': [2008, 2074, 2080, 2160, 2871, 3831, 3877, 3937], 'EDTA': [2009], 'saline': [2012], '(PBS)': [2013], '(Ca2+': [2014], 'Mg2+': [2016], 'free)': [2017], '45': [2019, 2549, 3052], 'min': [2020, 2311, 2799, 3053, 3228], '°C.': [2023, 2261], 'chilled': [2028], 'ice': [2030], 'epidermis': [2033], 'quickly': [2035], 'peeled': [2036], 'away': [2037], 'dermis.': [2040], 'immediately': [2044], 'snap': [2045], 'frozen': [2046], 'liquid': [2048], 'nitrogen': [2049, 2543], 'stored': [2051], '-80': [2053], 'until': [2055, 3011], 'extracted.': [2058], 'Activity': [2060], 'Assays—Liver': [2061], 'newborn': [2067, 2355, 2786, 3310, 3359, 3746, 4161, 4168, 4325], 'separately': [2070], 'homogenized': [2071], '50': [2073], 'Tris-HCl': [2075], '(pH': [2076, 2996, 3043], '7.4)': [2077], '250': [2079], 'sucrose': [2081], 'strokes': [2084], 'Potter-Elvehjem': [2087], 'homogenizer.': [2089], 'debris': [2091], 'nuclei': [2093], 'pelleted': [2095], 'centrifugation': [2097], '×': [2100], 'g': [2101, 4080], '5': [2103, 2310, 2323, 2695, 2801, 2834, 3160], 'min.': [2104, 2324, 2550, 2741], 'supernatant': [2106], '(10-50': [2107], 'protein)': [2110], 'assays,': [2118, 3556], 'described': [2121, 2384, 2497, 2614, 3451], 'either': [2156, 3023], '100': [2159, 2546, 3876], 'MgCl2': [2161, 3832], 'assay': [2164, 3203, 3827, 3873], 'buffer.': [2165, 2815], 'Blood': [2166], 'Chemistries—Plasma': [2167], 'free': [2170, 4316], 'concentrations': [2173], 'measured': [2175, 2646, 3198, 3266, 3336, 3449, 3552, 3579], 'colorimetric': [2177], '(Triglycerides': [2180], 'GPO': [2181], 'Free': [2183], 'Fatty': [2184, 2577], 'Half-Micro': [2185], 'Test,': [2186], 'Roche': [2187, 2198], 'Diagnostics).': [2188, 2199], 'Plasma': [2189, 4337], 'glucose': [2190, 3196, 3202, 4320, 4338], 'determined': [2193, 2430], 'glucometer': [2196], '(Accu-chek,': [2197], 'Analyses—Lipids': [2201], 'total': [2205], 'carcass': [2206, 2373], 'homogenates': [2209], 'ClCH3:MeOH': [2211], '(2:1)': [2212], 'separated': [2214, 2492, 2582, 2897], 'thin-layer': [2216], 'chromatography': [2217, 2382, 2569, 2588], 'solvent': [2220], 'hexane:ethyl': [2222], 'ether:acetic': [2223], '(80:20:1)': [2225], 'Silica': [2227], 'Gel': [2228], 'G-60': [2229], 'TLC': [2230, 2495, 2648, 2672], 'plates.': [2231], 'Lipids': [2232, 2742, 2890], 'visualized': [2234, 2343], 'exposure': [2236], 'iodine': [2238], 'vapor': [2239], 'charred': [2241, 2735], 'dipping': [2243], 'plate': [2245], 'solution': [2248, 2723], 'cupric': [2251, 2725], 'sulfate': [2252, 2726, 3168], '8%': [2254], 'phosphoric': [2255], 'heating': [2258], '180': [2260], 'Triglyceride': [2262, 2777, 3499, 3939], 'mass': [2263, 3604], 'quantified': [2265, 2584, 2744], 'method': [2268, 2462], 'Snyder': [2270], 'Stephens': [2272, 2275], '(22Snyder': [2273], 'F.': [2274], 'N.A.': [2276], '1959;': [2280, 2660], '34:': [2281], '244-245Crossref': [2282], '(361)': [2285], 'triolein': [2289], 'standard.': [2292], 'visualize': [2294, 2935], 'neutral': [2295, 2936], 'lipid': [2296, 2486, 2528, 2650, 3626, 3633], 'droplets': [2297, 3627, 3634], 'intact': [2299], 'fixed': [2303, 2915, 2973], '1.5%': [2305, 3028, 3035], 'glutaraldehyde': [2306, 2982], 'PBS': [2308, 2920, 3215, 3235, 3243, 3249], 'stained': [2314, 2929, 2954, 3133, 3237], '0.1': [2316, 2991, 3003, 3039, 3189], 'Nile': [2318], 'Red': [2319, 2957], 'acetone': [2321], 'Cells': [2325, 2816], 'washed': [2328, 2818], 'twice': [2329, 2819], 'coverslips': [2333], 'mounted': [2335], 'drop': [2338], 'PBS.': [2340], 'Fluorescence': [2341], 'fluorescein': [2345], 'isothiocyanate': [2346], 'optics.': [2347], 'compositional': [2349], 'analyses,': [2350], 'lipids': [2351, 2377, 2423, 2438, 2644, 2937], 'carcasses,': [2357], 'plasma,': [2358], 'milk': [2363, 2371], 'produced': [2364, 3789], 'DGAT2-heterzygote': [2366], 'females.': [2367], 'Methyl': [2368], 'esters': [2369, 2556, 2580], 'gas-liquid': [2381], 'experiments,': [2419], 'composition': [2421], 'liver': [2428, 2444, 2939, 3818, 3868], 'high-throughput': [2432], 'methods': [2433], 'developed': [2434, 4004], 'Lipomics.': [2436], '(200': [2441], 'μl)': [2442], '(25': [2445], 'mg)': [2446], 'chloroform:methanol': [2450], '(2:1,': [2451], 'v/v)': [2452, 2691, 2702], 'presence': [2455], 'authentic': [2457], 'internal': [2458], 'standards': [2459], 'Folch': [2464], 'et': [2465, 2500], 'al.': [2466, 2501], '(23Folch': [2467], 'Lees': [2469], 'Stanley': [2471], 'G.H.S.': [2472], '1957;': [2476], '226:': [2477], '497-509Abstract': [2478], 'Individual': [2485], 'classes': [2487, 2529], 'within': [2488], 'extract': [2490], 'preparative': [2494], 'Watkins': [2499], '(24Watkins': [2502, 2615], 'S.M.': [2503, 2616], 'Lin': [2504, 2617], 'T.Y.': [2505, 2618], 'Davis': [2506, 2619], 'Ching': [2508, 2621], 'J.R.': [2509, 2622], 'DePeters': [2510, 2623], 'E.J.': [2511, 2624], 'Halpern': [2512, 2625], 'G.M.': [2513, 2626], 'Walzem': [2514, 2627], 'R.L.': [2515, 2628], 'German': [2516, 2629], 'J.B.': [2517, 2630], 'Lipids.': [2518, 2631], '36:': [2520, 2633], '247-254Crossref': [2521, 2634], '(62)': [2524, 2637], 'Isolated': [2527], 'trans-esterified': [2531], 'n': [2534, 3161, 3180, 3186, 3959, 3963, 3967, 4027, 4045, 4084], 'methanolic': [2535], 'HCl': [2536, 3181], 'sealed': [2539], 'vial': [2540], 'under': [2541, 2575], 'atmosphere': [2544], 'resulting': [2552, 3778], 'methyl': [2555, 2579], 'hexane': [2560, 2573], '0.05%': [2562], 'butylated': [2563], 'hydroxytoluene': [2564], 'prepared': [2566], 'gas': [2568, 2587, 2591], 'sealing': [2571], 'extracts': [2574], 'nitrogen.': [2576], 'capillary': [2586, 2603], 'using': [2589, 3935], 'chromatograph': [2592], '(Hewlett-Packard': [2593], 'model': [2594], '6890,': [2595], 'Wilmington,': [2596, 2752], 'DE)': [2597], 'equipped': [2598], '30-m': [2601], 'DB-225MS': [2602], 'column': [2604], '(J&W': [2605], 'Scientific,': [2606, 2751], 'Folsom,': [2607], 'CA)': [2608], 'flame-ionization': [2611], 'detector': [2612], 'Acylceramide': [2640], 'extraction': [2651], '(25Bligh': [2652], 'E.G.': [2653], 'Dyer': [2654], 'W.J.': [2655], 'Can.': [2656], '37:': [2661], '911-917Crossref': [2662], '(43132)': [2665], 'following': [2669], 'one-dimensional,': [2670], 'high-performance': [2671], 'systems': [2673], 'optimal': [2675], 'separation': [2676], 'quantification': [2678], 'ceramide': [2680], 'glucosylceramide': [2682], 'species': [2683], 'subsequent': [2685], 'scanning': [2686, 2748], 'densitometry:': [2687], '(i)': [2688], 'chloroform:methanol:water': [2689], '(40:10:1,': [2690], 'cm,': [2696], 'successively;': [2697], '(ii)': [2698], 'chloroform:methanol:acetic': [2699], '(94:4:1.5,': [2701], 'top;': [2705], '(iii)': [2707], 'n-hexane:diethyether:acetic': [2708], '(65:35:1,': [2710], 'v/v).': [2711], 'final': [2713], 'development,': [2714, 4211], 'plates': [2716], 'dried,': [2718], 'cooled,': [2719], 'dipped': [2720], 'charring': [2722], '(1.5%': [2724], 'acetic': [2728], 'acid:sulfuric': [2729], 'acid:orthophosphoric': [2730], 'acid:water': [2731], '(50:10:10:30,': [2732], 'v/v)),': [2733], '160': [2737], 'CAMAG': [2747], 'densitometer': [2749], '(CAMAG': [2750], 'NC)': [2753], '(26Holleran': [2754], 'W.M.': [2755], 'Man': [2756], 'M.Q.': [2757], 'Gao': [2758], 'W.N.': [2759], 'Menon': [2760, 3082], 'G.K.': [2761, 3083], 'Elias': [2762, 3086, 3277], 'P.M.': [2763, 3087, 3278], 'Feingold': [2764, 3279], 'K.R.': [2765, 3280], '1991;': [2769, 3091], '88:': [2770, 3066], '1338-1345Crossref': [2771], '(213)': [2774], 'Synthesis': [2778, 3940], 'Intact': [2780], 'Liver': [2781, 3155], 'Cells—Livers': [2782], 'removed': [2784, 3440], 'mice,': [2787, 3985, 4303], 'cut': [2788, 2925], 'pieces,': [2791], '2%': [2804, 2981, 2984], 'collagenase': [2805], '1%': [2808], 'albumin': [2811, 2876], 'Krebs-Ringer': [2813], 'phosphate': [2814], 'medium,': [2827, 2837], 'serum,': [2831], 'resuspended': [2832], 'plated': [2839], 'dish.': [2844], '80-90%': [2848, 3752], 'assessed': [2850], 'staining': [2852], 'trypan': [2854], 'blue.': [2855], 'fresh': [2862], 'μCi': [2866], '[3H]glycerol': [2868, 3584], '±': [2869, 3459, 4020, 4024, 4038, 4042, 4074, 4078], 'oleate,': [2872], '0.5%': [2873], 'added,': [2878], 'CO2': [2888], 'overnight.': [2889], 'TLC,': [2899], 'incorporation': [2902, 3582], 'radiolabel': [2904], 'phospholipid': [2908], 'determined.': [2910], 'Histological': [2911], 'Analyses—Newborn': [2912], '4%': [2917], 'paraformaldeyde': [2918], 'overnight,': [2921], 'embedded': [2922, 3117], 'paraffin,': [2924], 'sections,': [2927], 'hematoxylin': [2931], 'eosin.': [2933], '(BAT),': [2944], 'snap-frozen': [2947], 'OCT': [2949], 'isopentane,': [2951], 'sectioned,': [2952], 'Oil': [2956], 'O.': [2958], 'ultrastructural': [2960], 'biopsy': [2963], 'scale': [2965], 'minced': [2968], '1-mm3': [2970], 'pieces': [2971, 3353], 'overnight': [2974], '(16': [2975], 'h)': [2976], '4': [2978, 3009, 3185, 3687, 3775], 'paraformaldehyde': [2985], '0.06%': [2987], 'calcium': [2988], 'chloride': [2989], 'm': [2992, 3004, 3040, 3190], 'sodium': [2993, 3005, 3041, 3167], 'cacodylate': [2994, 3006, 3042], 'buffer': [2995, 3007], '7.3).': [2997], 'Specimens': [2998], 'placed': [3001, 3021, 3365], 'further': [3012], 'processing.': [3013], 'Portions': [3014], '0.2%': [3024], 'ruthenium': [3025], 'tetroxide': [3026, 3030], 'osmium': [3029], '(Polysciences,': [3031], 'Warrington,': [3032, 3273], 'PA)': [3033, 3274], 'potassium': [3036], 'ferrocyanide': [3037], '7.4),': [3044], 'room': [3046, 3260], 'temperature': [3047, 3334], '(27Madison': [3054], 'K.C.': [3055], 'Swartzendruber': [3056], 'D.C.': [3057], 'Wertz': [3058], 'P.W.': [3059], 'Downing': [3060], 'D.T.': [3061], 'Investig.': [3063, 3089], 'Dermatol.': [3064, 3090], '1987;': [3065], '714-718Abstract': [3067], '(331)': [3073], '28Hou': [3076], 'S.Y.': [3077], 'Mitra': [3078], 'A.K.': [3079], 'White': [3080], 'S.H.': [3081], 'Ghadially': [3084], '96:': [3092], '215-223Abstract': [3093], '(265)': [3099], 'rinsing': [3103], 'buffer,': [3105], 'dehydrated': [3109, 3218], 'graded': [3112], 'ethanol': [3113, 3170], 'series,': [3114], 'subsequently': [3116], 'low': [3120], 'viscosity,': [3121], 'epoxy': [3122], 'resin': [3123], 'DER': [3125], '736': [3126], 'Epon': [3128], '812.': [3129], 'Thin': [3130], 'sections': [3131], 'lead': [3135], 'citrate': [3136], 'and/or': [3137], 'uranyl': [3138], 'acetate': [3139], 'examined': [3141, 4213, 4305], 'Zeiss': [3144], '10A': [3145], 'electron': [3146], 'microscope': [3147], '(Zeiss,': [3148], 'Thornville,': [3149], 'NY)': [3150], 'operating': [3151], '60': [3153], 'kV.': [3154], 'Glycogen—Livers': [3156], 'KOH': [3162, 3187], 'treated': [3164], 'saturated': [3166], 'isolate': [3172], 'glycogen': [3173, 4352], 'granules.': [3174], 'Samples': [3175], 'boiled': [3177], 'neutralized': [3183], 'triethylamine': [3191], 'release': [3193], 'glucose.': [3194], 'Glycogen-derived': [3195], '(Sigma': [3205], '115-A).': [3206], 'Skin': [3207, 3332, 3350], 'Barrier': [3208], 'Function': [3209], 'Assays—Newborn': [3210], 'rinsed': [3213], 'successively': [3217], '25,': [3220], '50,': [3221], '75,': [3222], '100%': [3224], 'methanol': [3225], 'each.': [3229], 'rehydrated': [3233], '0.1%': [3239], 'toluidine': [3240], 'blue': [3241], 'destained': [3247], 'photographed.': [3255], 'steps': [3257], 'temperature.': [3261], 'Transepidermal': [3262], 'water': [3263, 3270, 3307, 3329, 3446], 'loss': [3264, 3308, 3330, 3447], 'electrolytic': [3269], 'analyzer': [3271], '(MEECO,': [3272], '(29Grubauer': [3275], 'Res.': [3283], '1989;': [3284], '30:': [3285], '323-333Abstract': [3286], 'Because': [3293], 'locations,': [3299], 'instruments': [3302, 3319], 'measure': [3306], 'received': [3315], 'grafts.': [3317], 'sensitivities,': [3322], 'providing': [3323], 'ranges': [3325], 'absolute': [3327], 'transepidermal': [3328, 3445], 'measurements.': [3331], 'surface': [3333], 'digital': [3339], 'thermometer': [3340], '(model': [3341], '4600;': [3342], 'Yellow': [3343, 3346], 'Springs': [3344], 'Instruments,': [3345], 'Springs,': [3347], 'OH).': [3348], 'Grafts—Full-thickness': [3351], '(∼1': [3354], 'cm2)': [3355], 'obtained': [3357], 'wild-type': [3360, 3927, 3984, 4052, 4082, 4100, 4335, 4357], 'pups': [3363], 'medium.': [3370], 'Wild-type': [3371], 'grafted': [3376], 'onto': [3377, 3393], 'left': [3379], 'right': [3381], 'sides': [3382], 'athymic': [3384], 'nude': [3385], '(Jackson': [3387], 'Laboratory,': [3388], 'Bar': [3389], 'Harbor,': [3390], 'ME),': [3391], 'respectively,': [3392, 3568, 3822], 'wound': [3395], 'created': [3396], 'removing': [3398], 'similar-sized': [3400], 'piece': [3401], 'full-thickness': [3403], 'Wound': [3405], 'edges': [3406], 'sutured': [3408], 'allowed': [3412], 'recover.': [3414], 'supplemented': [3418], 'tablets': [3420], "(SCID's": [3421], 'MD,': [3422], 'Bio-Serv,': [3423], 'Frenchtown,': [3424], 'NJ)': [3425], 'sulfamethoxazole': [3427], '(60': [3428], 'mg/tablet)': [3429], 'trimethoprim': [3431], '(10': [3432], 'mg/tablet).': [3433], 'Three': [3434], 'weeks': [3435], 'transplantation,': [3437], 'fur': [3438], 'grafts': [3443], 'above.': [3452], 'Statistical': [3453], 'Analyses—Data': [3454], 'presented': [3456], 'mean': [3458], 'S.D.': [3460], 'unless': [3461], 'otherwise': [3462], 'indicated.': [3463], 'parametric': [3465], 'data,': [3466, 3485], 'means': [3467], 'compared': [3469], 't': [3471], 'test': [3472, 3489, 3492, 3661], 'analysis': [3475], 'variance': [3477], 'Student-Newman-Keuls': [3481], 'test.': [3482], 'nonparametric': [3484], 'Mann-Whitney': [3487], 'rank-sum': [3488], 'Kruskal-Wallis': [3491], 'used.': [3494], 'Overexpression': [3495], 'Promotes': [3498], 'Storage': [3500], 'Cultured': [3502], 'Cells—To': [3503], 'examine': [3504], 'cellular': [3512], 'overexpressed': [3516], 'FLAG-tagged': [3517], '(∼50-kDa)': [3520], '(∼42-kDa)': [3523], 'McA-RH7777': [3525], 'cells.': [3526], 'lines,': [3532], 'considerably': [3537, 3639], 'higher': [3538, 3562, 3591, 3607, 3845], 'than': [3539, 3569, 3594, 3610, 3852, 4051, 4331], '(Fig.': [3542, 3574, 3598, 3614, 3628, 3703, 3736, 3753, 3833, 3990, 4251, 4328, 4349], '1a).': [3543], 'reflected': [3546], 'levels,': [3550], '11-': [3559], '3-fold': [3561], 'DGAT2-overexpressing': [3566], 'LacZ-transfected': [3571], 'control': [3572], '1b).': [3575], '2-fold': [3590], 'DGAT2-': [3593, 3609], 'DGAT1-overexpressing': [3596, 3612], '1c).': [3599], 'Additionally,': [3600], 'intracellular': [3602, 3620, 3655], '4-fold': [3606], '1d).': [3615], 'DGAT2-transfected': [3617], 'accumulated': [3622], 'large': [3624], 'cytosolic': [3625], '1e).': [3629], 'DGAT1-transfected': [3631], 'smaller.': [3640], 'suggested': [3643], 'potently': [3647], 'triglycerides.': [3656], 'Mice—To': [3660], 'vivo,': [3672], 'gene-targeting': [3678], 'designed': [3681], 'replace': [3683], 'exons': [3684, 3772], 'murine': [3689, 3848], 'Dgat2,': [3690], 'regions': [3691], 'highly': [3694], 'conserved': [3695], 'family': [3699], 'members,': [3700], 'and,': [3714], 'subsequently,': [3715], 'targeted': [3719], 'Homozygous': [3721], '2b).': [3737], 'mRNA': [3739, 3758, 4114], 'BAT': [3742, 3820, 3842, 3851, 3870], 'livers': [3744, 4158], '2c).': [3754], 'residual': [3756], 'nonfunctional.': [3763], 'Amplification': [3764], 'sequencing': [3766], 'transcript': [3769], 'deleted,': [3777], 'introduction': [3781], 'premature': [3784], 'stop': [3785], 'codon.': [3786], 'allele': [3792], 'would': [3793], 'be': [3794], 'severely': [3795], 'truncated': [3796], '(112': [3797], 'amino': [3798, 3806], 'instead': [3800], '387)': [3802], '29': [3804], 'novel': [3805], 'acids.': [3807], '53': [3813], '35%': [3815], 'homogenates,': [3821], 'when': [3823, 3871], '2d).': [3834], 'lesser': [3836], 'reduction': [3837, 3860, 4064, 4263], 'may': [3843], 'reflect': [3844], 'Dgat1': [3849], 'liver.': [3854], '2S.': [3855], 'Stone,': [3856], 'unpublished': [3857], 'results.': [3858], 'No': [3859], 'MgCl2,': [3878], 'condition': [3880], 'selectively': [3882], 'measures': [3883], '(not': [3919, 4267], 'shown).': [3920], 'MgCl2.': [3938], 'Is': [3943], 'Essential': [3944], 'Energy': [3946], 'Homeostasis—Offspring': [3947], 'heterozygote': [3949], 'intercrosses': [3950], 'expected': [3955], 'Mendelian': [3956], 'distribution': [3957], '(wild-type,': [3958], '=': [3960, 3964, 3968, 3971, 4028, 4046, 4085, 4088], '14;': [3961, 3969], 'Dgat2+/-,': [3962], '29;': [3965], 'Dgat2-/-,': [3966], 'p': [3970, 4030, 4048, 4087], '0.999': [3972], 'χ2': [3974], 'test).': [3975], 'healthy': [3980], 'indistinguishable': [3982], 'smaller': [3989], '2e),': [3991], 'rarely': [3992], 'suckled,': [3993], 'died': [3995], '2-24': [3996], 'birth.': [3999], 'Necrosis': [4000], 'tail': [4003], 'survived': [4009], '8-24': [4011], 'h.': [4012], 'Newborn': [4013], 'weighed': [4016], '20%': [4017], 'less': [4018], '(1.13': [4019], '0.12': [4021], 'versus': [4022, 4040, 4076], '1.41': [4023], '0.14': [4025], 'g,': [4026], '16-18,': [4029], '<': [4031, 4049], '0.001)': [4032, 4050], '15%': [4035], 'shorter': [4036], '(2.5': [4037], '0.11': [4039], '2.9': [4041], '0.09': [4043, 4075], 'mm,': [4044], '3-5,': [4047], 'littermates,': [4053], 'suggesting': [4054, 4269], 'intrauterine': [4055, 4125], 'retardation.': [4057], 'Fetal': [4058], '14%': [4063], 'body': [4066], 'weight': [4067, 4135], 'day': [4070], '(E)': [4071], '18.5': [4072], '(0.97': [4073], '1.13': [4077], '0.08': [4079], 'embryos,': [4083, 4103], '4,': [4086, 4329], '0.04).': [4089], 'At': [4090, 4256], 'E12.5,': [4091, 4257], 'there': [4092], 'difference': [4095], 'size': [4098], 'retardation': [4107], 'occurred': [4108], 'later': [4109], 'development.': [4111, 4294], 'Levels': [4112], 'insulin-like': [4117], '1,': [4121], 'marker': [4123], 'nutrition': [4127], 'whose': [4128], 'inversely': [4131], 'correlated': [4132], 'birth': [4134], '(30Holt': [4136], 'R.I.': 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'updated_date': '2025-01-09T20:08:17.292870', 'created_date': '2016-06-24'}