Publication Information

{'id': 'https://openalex.org/W2069938136', 'doi': 'https://doi.org/10.1111/j.1755-3768.2013.3731.x', 'title': 'The limbal stem cell niche', 'display_name': 'The limbal stem cell niche', 'publication_year': 2013, 'publication_date': '2013-08-01', 'ids': {'openalex': 'https://openalex.org/W2069938136', 'doi': 'https://doi.org/10.1111/j.1755-3768.2013.3731.x', 'mag': '2069938136'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1755-3768.2013.3731.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S21165490', 'display_name': 'Acta Ophthalmologica', 'issn_l': '1755-375X', 'issn': ['1755-375X', '1755-3768'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001982732', 'display_name': 'Alex J. Shortt', 'orcid': 'https://orcid.org/0000-0001-6576-3875'}, 'institutions': [{'id': 'https://openalex.org/I4210150574', 'display_name': 'Moorfields Eye Hospital', 'ror': 'https://ror.org/03tb37539', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1325675289', 'https://openalex.org/I4210150574']}, {'id': 'https://openalex.org/I4210138523', 'display_name': 'UCL Biomedical Research Centre', 'ror': 'https://ror.org/03r9qc142', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I1340918713', 'https://openalex.org/I34931013', 'https://openalex.org/I4210138523', 'https://openalex.org/I45129253']}, {'id': 'https://openalex.org/I4210131026', 'display_name': 'Institute of Ophthalmology', 'ror': 'https://ror.org/036awca68', 'country_code': 'MX', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210131026']}, {'id': 'https://openalex.org/I45129253', 'display_name': 'University College London', 'ror': 'https://ror.org/02jx3x895', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I45129253']}], 'countries': ['GB', 'MX'], 'is_corresponding': True, 'raw_author_name': 'AJ SHORTT', 'raw_affiliation_strings': ['Moorfields Eye Hospital, London', 'NIHR Biomedical Research Centre, London', 'UCL Institute of Ophthalmology, London'], 'affiliations': [{'raw_affiliation_string': 'Moorfields Eye Hospital, London', 'institution_ids': ['https://openalex.org/I4210150574', 'https://openalex.org/I45129253']}, {'raw_affiliation_string': 'NIHR Biomedical Research Centre, London', 'institution_ids': ['https://openalex.org/I4210138523']}, {'raw_affiliation_string': 'UCL Institute of Ophthalmology, London', 'institution_ids': ['https://openalex.org/I4210131026', 'https://openalex.org/I45129253']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5001982732'], 'corresponding_institution_ids': ['https://openalex.org/I4210150574', 'https://openalex.org/I4210138523', 'https://openalex.org/I4210131026', 'https://openalex.org/I45129253'], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 65}, 'biblio': {'volume': '91', 'issue': 's252', 'first_page': '0', 'last_page': '0'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11828', 'display_name': 'Corneal Surgery and Treatments', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11828', 'display_name': 'Corneal Surgery and Treatments', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10997', 'display_name': 'Ocular Surface and Contact Lens', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10563', 'display_name': 'Corneal surgery and disorders', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/stem-cell-niche', 'display_name': 'Stem cell niche', 'score': 0.81919634}], 'concepts': [{'id': 'https://openalex.org/C153991713', 'wikidata': 'https://www.wikidata.org/wiki/Q17142856', 'display_name': 'Niche', 'level': 2, 'score': 0.9238912}, {'id': 'https://openalex.org/C164794517', 'wikidata': 'https://www.wikidata.org/wiki/Q16729831', 'display_name': 'Stem cell niche', 'level': 4, 'score': 0.81919634}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.76088667}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.58174145}, {'id': 'https://openalex.org/C102715595', 'wikidata': 'https://www.wikidata.org/wiki/Q172861', 'display_name': 'Ecological niche', 'level': 3, 'score': 0.5400404}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.43475187}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.1301972}, {'id': 'https://openalex.org/C201750760', 'wikidata': 'https://www.wikidata.org/wiki/Q1896218', 'display_name': 'Progenitor cell', 'level': 3, 'score': 0.059713423}, {'id': 'https://openalex.org/C185933670', 'wikidata': 'https://www.wikidata.org/wiki/Q52105', 'display_name': 'Habitat', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1755-3768.2013.3731.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S21165490', 'display_name': 'Acta Ophthalmologica', 'issn_l': '1755-375X', 'issn': ['1755-375X', '1755-3768'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.6, 'id': 'https://metadata.un.org/sdg/15', 'display_name': 'Life on land'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4388745874', 'https://openalex.org/W3183539837', 'https://openalex.org/W3114103876', 'https://openalex.org/W3102059334', 'https://openalex.org/W3045983630', 'https://openalex.org/W2981567463', 'https://openalex.org/W2777552974', 'https://openalex.org/W2774948409', 'https://openalex.org/W2095253586', 'https://openalex.org/W1985545421'], 'abstract_inverted_index': {'Abstract': [0], 'Stem': [1], 'cells': [2, 42, 68], 'contain': [3], 'intrinsic': [4], 'mechanisms': [5], 'that': [6, 95], 'control': [7], 'their': [8, 50, 73, 146], 'behaviour': [9], 'but': [10, 113], 'the': [11, 18, 32, 61, 76, 99, 105, 114, 121, 139, 172, 175, 179, 182], 'environment': [12], 'immediately': [13], 'surrounding': [14], 'them,': [15], 'known': [16], 'as': [17, 88], 'niche,': [19, 119], 'also': [20], 'plays': [21], 'a': [22, 26, 117, 142], 'fundamental': [23], 'role.': [24], 'In': [25], 'host': [27], 'of': [28, 79, 98, 104, 116, 123, 141, 145, 174, 178, 184], 'tissues': [29], 'and': [30, 47, 84, 157, 181], 'organisms': [31], 'stem': [33, 41, 53, 67, 89, 165, 191], 'cell': [34, 54, 166, 192], 'niche': [35, 56, 74, 101, 151, 180, 186], 'has': [36, 130, 153], 'been': [37, 154], 'shown': [38], 'to': [39, 48, 86, 136], 'maintain': [40], 'in': [43, 75, 110, 120, 138], 'an': [44, 96], 'undifferentiated': [45], 'state': [46], 'regulate': [49], 'behaviour.': [51], 'This': [52], '–': [55], 'principle': [57], 'is': [58], 'typified': [59], 'by': [60], 'corneal': [62], 'limbus.': [63], 'When': [64], 'limbal': [65, 77, 164], 'epithelial': [66], '(LESC)': [69], 'are': [70, 171], 'dissociated': [71], 'from': [72], 'palisades': [78], 'Vogt': [80], 'they': [81], 'rapidly': [82], 'differentiate': [83], 'cease': [85], 'function': [87], 'cells.': [90], 'It': [91], 'might': [92], 'be': [93, 103], 'imagined': [94], 'understanding': [97, 144], 'LESC': [100, 134, 150], 'would': [102], 'highest': [106], 'priority': [107], 'for': [108, 163], 'researchers': [109], 'this': [111], 'field': [112], 'existence': [115], 'surrogate': [118], 'form': [122], 'growth': [124], 'arrested': [125], '3T3': [126], 'fibroblast': [127], 'feeder': [128], 'layers,': [129], 'allowed': [131], 'research': [132, 152], 'on': [133], 'biology': [135], 'progress': [137], 'absence': [140], 'thorough': [143], 'native': [147], 'niche.': [148], 'Thankfully': [149], 'gathering': [155], 'momentum': [156], 'several': [158], 'exciting': [159], 'developments': [160], 'hold': [161], 'promise': [162], 'deficient': [167], 'patients.': [168], 'Amongst': [169], 'these': [170], 'characterisation': [173], 'physical': [176], 'structure': [177], 'identification': [183], 'mesenchymal': [185], 'cells,': [187], 'which': [188], 'themselves': [189], 'displaying': [190], 'properties.': [193]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069938136', 'counts_by_year': [], 'updated_date': '2024-12-12T03:29:45.069852', 'created_date': '2016-06-24'}