Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2069781108', 'doi': 'https://doi.org/10.1016/j.bbrc.2004.08.161', 'title': 'Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53', 'display_name': 'Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53', 'publication_year': 2004, 'publication_date': '2004-10-01', 'ids': {'openalex': 'https://openalex.org/W2069781108', 'doi': 'https://doi.org/10.1016/j.bbrc.2004.08.161', 'mag': '2069781108', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15381073'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2004.08.161', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5089422405', 'display_name': 'Shingo Komiyama', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shingo Komiyama', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034430377', 'display_name': 'S. Taniguchi', 'orcid': 'https://orcid.org/0000-0002-7461-8300'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sachiko Taniguchi', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012263160', 'display_name': 'Yoshihisa Matsumoto', 'orcid': 'https://orcid.org/0000-0002-0758-290X'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Yoshihisa Matsumoto', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003560915', 'display_name': 'Eri Tsunoda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Eri Tsunoda', 'raw_affiliation_strings': ['Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032119252', 'display_name': 'Takayo Ohto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takayo Ohto', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056944762', 'display_name': 'Yuka Suzuki', 'orcid': 'https://orcid.org/0000-0002-2288-7162'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuka Suzuki', 'raw_affiliation_strings': ['Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiological Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019134693', 'display_name': 'Hong-Lan Yin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hong-Lan Yin', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102156698', 'display_name': 'Masanori Tomita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masanori Tomita', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016934524', 'display_name': 'Atsushi Enomoto', 'orcid': 'https://orcid.org/0000-0002-4149-6247'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Atsushi Enomoto', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050428602', 'display_name': 'Akinori Morita', 'orcid': 'https://orcid.org/0000-0001-9988-6136'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I4210110652', 'display_name': 'RIKEN', 'ror': 'https://ror.org/01sjwvz98', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210110652']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akinori Morita', 'raw_affiliation_strings': ['Applications Development Division, Cyclotron Center, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan', 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Applications Development Division, Cyclotron Center, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan', 'institution_ids': ['https://openalex.org/I4210110652']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101533091', 'display_name': 'Takahiko Suzuki', 'orcid': 'https://orcid.org/0000-0002-4752-0842'}, 'institutions': [{'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takahiko Suzuki', 'raw_affiliation_strings': ['School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067868993', 'display_name': 'Kuni Ohtomo', 'orcid': 'https://orcid.org/0000-0003-3332-854X'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kuni Ohtomo', 'raw_affiliation_strings': ['Department of Radiation Research, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Research, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068612571', 'display_name': 'Yoshio Hosoi', 'orcid': 'https://orcid.org/0000-0003-3434-594X'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshio Hosoi', 'raw_affiliation_strings': ['Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'School of Life Science, Tokyo University of Pharmacy and Life Science, 1932-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5019392035', 'display_name': 'Norio Suzuki', 'orcid': 'https://orcid.org/0000-0001-6100-3350'}, 'institutions': [{'id': 'https://openalex.org/I79072001', 'display_name': 'International University of Health and Welfare', 'ror': 'https://ror.org/053d3tv41', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I79072001']}, {'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I4210110652', 'display_name': 'RIKEN', 'ror': 'https://ror.org/01sjwvz98', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210110652']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Norio Suzuki', 'raw_affiliation_strings': ['Applications Development Division, Cyclotron Center, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan', 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'Department of Radiological Sciences, School of Health Science, International University of Health and Welfare, 2600-1, Kitakanamaru, Ohtawara, Tochigi 324-8501, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiological Sciences, School of Health Science, International University of Health and Welfare, 2600-1, Kitakanamaru, Ohtawara, Tochigi 324-8501, Japan', 'institution_ids': ['https://openalex.org/I79072001']}, {'raw_affiliation_string': 'Department of Radiation Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan', 'institution_ids': ['https://openalex.org/I74801974']}, {'raw_affiliation_string': 'Applications Development Division, Cyclotron Center, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan', 'institution_ids': ['https://openalex.org/I4210110652']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5012263160'], 'corresponding_institution_ids': ['https://openalex.org/I74801974', 'https://openalex.org/I149964584'], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.046, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.797028, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '323', 'issue': '3', 'first_page': '816', 'last_page': '822'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10294', 'display_name': 'Molecular Mechanisms of Apoptosis and Cell Death', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dna-damage', 'display_name': 'DNA Damage', 'score': 0.526128}, {'id': 'https://openalex.org/keywords/p53', 'display_name': 'p53', 'score': 0.503634}, {'id': 'https://openalex.org/keywords/dna-pkcs', 'display_name': 'DNA-PKcs', 'score': 0.4893212}], 'concepts': [{'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.90092593}, {'id': 'https://openalex.org/C184235292', 'wikidata': 'https://www.wikidata.org/wiki/Q421851', 'display_name': 'Kinase', 'level': 2, 'score': 0.5772035}, {'id': 'https://openalex.org/C97029542', 'wikidata': 'https://www.wikidata.org/wiki/Q281417', 'display_name': 'Protein kinase A', 'level': 3, 'score': 0.561818}, {'id': 'https://openalex.org/C2779486608', 'wikidata': 'https://www.wikidata.org/wiki/Q387082', 'display_name': 'Ataxia-telangiectasia', 'level': 4, 'score': 0.55802876}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.50723815}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5023775}, {'id': 'https://openalex.org/C68748289', 'wikidata': 'https://www.wikidata.org/wiki/Q18030783', 'display_name': 'DNA-PKcs', 'level': 4, 'score': 0.4893212}, {'id': 'https://openalex.org/C87325107', 'wikidata': 'https://www.wikidata.org/wiki/Q7251493', 'display_name': 'Protein phosphorylation', 'level': 4, 'score': 0.46721852}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.4242205}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38274014}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36104634}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3344816}], 'mesh': [{'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012694', 'descriptor_name': 'Serine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051747', 'descriptor_name': 'DNA-Activated Protein Kinase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D012694', 'descriptor_name': 'Serine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012694', 'descriptor_name': 'Serine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2004.08.161', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15381073', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320912', 'funder_display_name': 'Ministry of Education, Culture, Sports, Science and Technology', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1640195411', 'https://openalex.org/W1760383320', 'https://openalex.org/W1966115284', 'https://openalex.org/W1975644211', 'https://openalex.org/W1979490110', 'https://openalex.org/W1986448084', 'https://openalex.org/W1990549862', 'https://openalex.org/W1995741673', 'https://openalex.org/W2000572584', 'https://openalex.org/W2005236007', 'https://openalex.org/W2034562270', 'https://openalex.org/W2044874191', 'https://openalex.org/W2051550009', 'https://openalex.org/W2054311839', 'https://openalex.org/W2058939604', 'https://openalex.org/W2061889131', 'https://openalex.org/W2063822655', 'https://openalex.org/W2064642458', 'https://openalex.org/W2068705865', 'https://openalex.org/W2072455635', 'https://openalex.org/W2079088689', 'https://openalex.org/W2086218293', 'https://openalex.org/W2089574530', 'https://openalex.org/W2109829677', 'https://openalex.org/W2168924996', 'https://openalex.org/W2177762706', 'https://openalex.org/W2179172619', 'https://openalex.org/W2180238508'], 'related_works': ['https://openalex.org/W4298195022', 'https://openalex.org/W4249995467', 'https://openalex.org/W3126864519', 'https://openalex.org/W2411596856', 'https://openalex.org/W2159423338', 'https://openalex.org/W2083061683', 'https://openalex.org/W2027189919', 'https://openalex.org/W1997245052', 'https://openalex.org/W1979109050', 'https://openalex.org/W1965019589'], 'abstract_inverted_index': {'DNA': [0, 28], 'damage': [1], 'induces': [2], 'accumulation': [3], 'and': [4, 67, 86, 141], 'activation': [5], 'of': [6, 16, 21, 27, 43, 58, 72, 117, 134], 'p53': [7, 59], 'via': [8, 144], 'various': [9], 'posttranslational': [10], 'modifications.': [11], 'Among': [12], 'them,': [13], 'several': [14], 'lines': [15], 'evidence': [17], 'indicated': [18], 'the': [19, 32, 41, 99], 'phosphorylation': [20, 64, 71, 116, 133, 138, 143], 'Ser46': [22, 57, 73, 122], 'as': [23], 'an': [24], 'important': [25], 'mediator': [26], 'damage-induced': [29], 'apoptosis': [30], 'but': [31], 'responsible': [33], 'kinase': [34, 53, 104], 'remains': [35], 'to': [36, 62, 111], 'be': [37, 112], 'clarified,': [38], 'especially': [39], 'in': [40, 60, 77, 95], 'case': [42], 'ionizing': [44], 'radiation': [45], '(IR).': [46], 'Here': [47], 'we': [48], 'showed': [49], 'that': [50], 'DNA-dependent': [51], 'protein': [52], '(DNA-PK)': [54], 'could': [55, 119], 'phosphorylate': [56, 121], 'addition': [61], 'reported': [63], 'sites': [65], 'Ser15': [66], 'Ser37.': [68], 'However,': [69], 'IR-induced': [70, 115, 132], 'was': [74, 109], 'seen': [75], 'even': [76], 'M059J,': [78], 'a': [79, 102], 'human': [80], 'glioma': [81], 'cell': [82], 'line': [83], 'lacking': [84], 'DNA-PKcs,': [85], 'it': [87], 'was,': [88], 'at': [89], 'most,': [90], 'only': [91], 'slightly': [92], 'less': [93], 'than': [94], 'control': [96], 'M059K.': [97], 'On': [98], 'other': [100], 'hand,': [101], 'related': [103], 'ataxia-telangiectasia': [105], 'mutated': [106], '(ATM),': [107], 'which': [108], 'shown': [110], 'essential': [113], 'for': [114, 131], 'Ser46,': [118, 135], 'poorly': [120], 'by': [123, 139], 'itself.': [124], 'These': [125], 'results': [126], 'collectively': [127], 'suggested': [128], 'two': [129], 'pathways': [130], 'i.e.,': [136], 'direct': [137], 'DNA-PK': [140], 'indirect': [142], 'ATM.': [145]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069781108', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-20T03:19:25.687353', 'created_date': '2016-06-24'}