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1419, 1427, 1452, 1457, 1489, 1574, 1594, 1681, 1712, 1990, 2194, 2199, 2223, 2241, 2312, 2328, 2371, 2419, 2459, 2462, 2471, 2508, 2561, 2573, 2581, 2612, 2659, 2667, 2687, 2694, 2726, 2734, 2746, 2749, 2760, 2763, 2791, 2798, 2806, 2840, 2863, 2894, 2924, 2930, 2955, 2974, 2982, 2994, 3010, 3123, 3152, 3157, 3240, 3307, 3430, 3488, 3501, 3515, 3542, 3548, 3559, 3653, 3686, 3712, 3819, 3849, 3890, 4099, 4161, 4173, 4183, 4192, 4214, 4223, 4258, 4278, 4306, 4309, 4318, 4348, 4351, 4361, 4366, 4389, 4399, 4509, 4555, 4576, 4605, 4627, 4630, 4633, 4698], 'adipocytes.': [13, 57, 73, 305, 349, 365, 1343, 1380, 2319, 2896, 3120], 'Although': [14, 306, 1344, 2235], 'the': [15, 43, 49, 179, 195, 198, 236, 307, 335, 341, 471, 488, 491, 529, 654, 680, 757, 886, 983, 1033, 1043, 1048, 1063, 1071, 1097, 1109, 1187, 1206, 1213, 1255, 1268, 1282, 1328, 1374, 1413, 1446, 1466, 1501, 1514, 1561, 1589, 1689, 1692, 1706, 1806, 1832, 1850, 1942, 2001, 2020, 2114, 2131, 2172, 2182, 2244, 2306, 2313, 2404, 2423, 2457, 2513, 2517, 2559, 2631, 2750, 2758, 2764, 2768, 2778, 2789, 2811, 2818, 2845, 2956, 2992, 3004, 3008, 3045, 3081, 3099, 3139, 3185, 3258, 3493, 3532, 3543, 3552, 3561, 3565, 3804, 3813, 3820, 3828, 3857, 3891, 3980, 3984, 4021, 4100, 4174, 4184, 4193, 4202, 4297, 4301, 4387, 4400, 4505, 4568, 4596, 4623, 4637, 4653, 4666, 4699, 4702], 'mechanism': [16, 308, 4285], 'for': [17, 309, 1189, 1194, 1438, 1508, 1579, 1653, 1691, 2015, 2038, 2051, 2217, 2482, 2527, 2534, 2603, 2650, 2712, 3568, 4050, 4272, 4652, 4685, 4690, 4696], 'LPL': [19, 58, 80, 110, 128, 136, 140, 160, 169, 176, 255, 276, 289, 311, 350, 372, 402, 420, 428, 432, 452, 461, 468, 548, 569, 582, 675, 705, 745, 752, 802, 806, 813, 816, 1338, 1362, 1377, 1520, 1612, 1658, 1678, 1737, 1741, 2078, 2139, 2228, 2254, 2300, 2308, 2322, 2363, 2387, 2426, 2435, 2460, 2472, 2503, 2510, 2557, 2562, 2577, 2582, 2591, 2607, 2615, 2637, 2651, 2663, 2688, 2695, 2705, 2731, 2747, 2761, 2792, 2799, 2807, 2983, 3011, 3062, 3126, 3146, 3162, 3175, 3183, 3220, 3239, 3261, 3269, 3280, 3302, 3489, 3497, 3503, 3513, 3528, 3546, 3654, 3666, 3834, 3852, 3877, 3894, 3916, 3964, 3985, 4018, 4177, 4207, 4352, 4390, 4395, 4418, 4563, 4615, 4634, 4658], 'not': [21, 266, 313, 559, 1349, 2546, 2555, 2802, 2892, 2970, 3094, 3901, 4642], 'known,': [22, 314], 'elevated': [23, 315, 4597], 'glucose': [24, 316, 1286, 3313, 4502, 4578, 4588], 'known': [26, 189, 318, 482, 876, 3020, 3682], 'to': [27, 66, 118, 190, 249, 319, 358, 410, 483, 542, 689, 877, 1040, 1062, 1417, 1500, 1506, 2018, 2129, 2257, 2347, 2366, 2464, 2684, 2691, 3021, 3072, 3078, 3118, 3193, 3309, 3432, 3591, 3683, 3719, 3914, 3979, 4157, 4386, 4665], 'increase': [28, 267, 320, 560, 703, 743, 878, 1350, 2693, 2805, 2954], 'diacylglycerol,': [29, 321, 1190], 'which': [30, 322, 882, 3074, 3108, 3223, 3237, 3556, 3817, 4035, 4113, 4276, 4287, 4304], 'activates': [31, 323, 1066], 'protein': [32, 137, 324, 429, 595, 803, 814, 846, 1125, 1130, 1997, 2035, 2140, 2184, 2652, 3971, 4025, 4204, 4263, 4359], 'kinase': [33, 325, 596, 847, 4042, 4083, 4084, 4313], 'C': [34, 244, 326, 537, 848, 1476, 1484, 1495, 3166, 3180], '(PKC).': [35, 327], 'To': [36, 120, 193, 233, 328, 412, 486, 526, 1556, 2402, 2454, 2585, 2634, 2697, 2809, 2897, 3096, 3536, 3825], 'determine': [37, 121, 329, 413, 2455, 2586, 2698, 3537], 'whether': [38, 122, 330, 414, 2456, 2587, 2699, 3538], 'PKC': [39, 200, 212, 220, 239, 241, 252, 264, 272, 287, 331, 493, 505, 513, 532, 534, 545, 557, 565, 580, 895, 986, 1029, 1061, 1067, 1102, 1121, 1124, 1129, 1174, 1232, 1246, 1262, 1331, 1347, 1356, 1368, 1471, 2183, 2821, 2848, 2876, 2932, 2995, 3023, 3050, 3053, 3102, 3539, 3569, 3586, 3685, 3708, 3823, 3838, 3843, 3861, 3869, 3874, 3885, 3899, 3908, 4015, 4051, 4098, 4149, 4167, 4179, 4199, 4209, 4249, 4288, 4345, 4354, 4609, 4626, 4640, 4649], 'involved': [41, 333, 3541, 3994, 4182, 4191, 4360], 'regulation': [44, 336, 643, 650, 755, 3194, 3259, 3278, 3544, 3892, 4103, 4175], 'LPL,': [46, 268, 338, 561, 1351, 1560, 1926, 3080, 3105, 3903], 'we': [47, 339, 2707, 2951, 3043, 3508, 3550, 3840, 3960, 4342, 4619], 'studied': [48, 340, 995, 3551], 'effect': [50, 76, 237, 342, 368, 530, 1329, 2298, 2501, 2812, 3046, 3083, 3100, 3553, 3562, 3662], '12-O-tetradecanoyl': [52, 344, 601, 1051], 'phorbol': [53, 345, 602, 1049, 1052, 1117], '13-acetate': [54, 346, 1053], '(TPA)': [55, 347, 1054], 'on': [56, 79, 348, 371, 1186, 1337, 1771, 2299, 2502, 2817, 3104, 3665, 3833, 4274, 4296], 'was': [60, 64, 82, 90, 138, 172, 204, 352, 356, 374, 382, 430, 464, 497, 1340, 1496, 1563, 1592, 1615, 1679, 1703, 1738, 1801, 1988, 1998, 2082, 2099, 2108, 2141, 2230, 2237, 2265, 2310, 2324, 2389, 2428, 2448, 2524, 2608, 2618, 2665, 2732, 2742, 2978, 3086, 3116, 3128, 3148, 3485, 3498, 3540, 3669], 'inhibited': [61, 254, 353, 547, 2231, 2266, 2326, 2360, 2434, 3061, 3129, 3149, 3842, 3876], 'when': [62, 354], 'TPA': [63, 78, 100, 117, 123, 148, 163, 187, 206, 355, 370, 392, 409, 415, 440, 455, 480, 499, 1065, 1104, 1336, 1450, 2216, 2233, 2275, 2280, 2293, 2335, 2359, 2433, 2446, 2465, 2481, 2497, 2549, 2552, 2565, 2588, 2626, 2815, 2842, 2885, 2947, 2967, 2989, 3015, 3647, 3664, 3680, 3798, 3832, 4256], 'added': [65, 248, 357, 541, 3117], 'cultures': [67, 359, 2352], '3T3-F442A': [69, 209, 361, 502, 1381, 1928, 2209, 2318, 2349, 2372, 2823, 2895, 2905, 3119], 'and': [70, 89, 135, 216, 226, 245, 362, 381, 427, 509, 519, 538, 626, 649, 657, 696, 815, 843, 980, 988, 1042, 1058, 1123, 1178, 1192, 1210, 1212, 1217, 1239, 1249, 1270, 1277, 1333, 1423, 1474, 1482, 1518, 1565, 1644, 1683, 1705, 1732, 1810, 1873, 1912, 1937, 1995, 2042, 2069, 2113, 2153, 2171, 2181, 2201, 2264, 2358, 2385, 2393, 2430, 2447, 2490, 2595, 2606, 2645, 2670, 2716, 2737, 2740, 2771, 2777, 2784, 2801, 2829, 2852, 2859, 2872, 2880, 2889, 2913, 2937, 2943, 2961, 3133, 3155, 3190, 3235, 3429, 3523, 3593, 3715, 3977, 4009, 4031, 4044, 4085, 4102, 4106, 4108, 4118, 4205, 4220, 4264, 4315, 4382, 4405, 4410, 4413, 4560, 4581, 4610, 4659, 4681, 4693], 'rat': [71, 363, 852, 2354, 2378], 'primary': [72, 364, 2106, 2134, 2152, 2164, 2351], 'inhibitory': [75, 367, 2297, 2500, 3082, 3661, 3829], 'observed': [83, 91, 375, 383, 2952, 3087, 3645], 'after': [84, 112, 144, 162, 376, 404, 436, 454, 1498, 2259, 2269, 2901, 2963, 2988, 3248, 3671], '6': [85, 96, 145, 377, 388, 437, 2270, 2431, 2623, 2855, 2944], 'h': [86, 146, 378, 438, 2261, 2271, 2624, 2856, 2936, 2945, 2987], 'treatment,': [88, 380, 2858], 'at': [92, 384, 653, 756, 1491, 1582, 1656, 1935, 2011, 2075, 2110, 2116, 2168, 2175, 2450, 2515, 2753, 2767, 2934, 2941, 3003, 3531], 'a': [93, 157, 283, 385, 449, 576, 613, 1235, 1359, 1370, 1595, 1648, 2083, 2367, 2469, 2532, 2571, 2579, 2685, 2743, 2796, 2864, 3110, 3196, 3249, 3887, 3911, 4024, 4037, 4082, 4170, 4211, 4307, 4316, 4349, 4606, 4631], 'concentration': [94, 386, 1448, 2444], 'nm.': [97, 389], '100': [98, 390, 1435, 2214, 2251, 2381, 2451, 2479, 2910], 'nm': [99, 391, 1436, 2215, 2252, 2382, 2432, 2452, 2480, 2911], 'yielded': [101, 393, 1931], 'maximal': [102, 394, 2449, 3172], '(80%)': [103, 395], 'inhibition': [104, 270, 279, 396, 563, 572, 1354, 2424, 2440, 3103, 3135, 3173, 3244, 3526, 3850, 3872, 4265, 4613], 'LPL.': [106, 398, 2723, 4196, 4644], 'No': [107, 399], 'stimulation': [108, 400, 1100, 1345, 3897, 4638], 'occurred': [111, 403, 3002, 3136], 'short': [113, 405, 794], 'term': [114, 182, 406, 475, 795, 3677], 'addition': [115, 407, 1499, 2346, 2495, 2902, 3056, 3092, 3140], 'cultures.': [119, 250, 411, 543], 'treatment': [124, 183, 207, 416, 476, 500, 688, 797, 810, 1044, 1115, 1834, 2249, 2263, 2273, 2291, 2376, 2466, 2553, 2566, 2589, 2627, 2816, 2843, 2861, 2968, 3016, 3648, 3673, 3678, 3799, 4252], 'adipocytes': [126, 210, 418, 503, 853, 1442, 1685, 1804, 1929, 2210, 2355, 2379, 2597, 2824, 2906, 3516, 4225, 4254, 4513, 4628], 'synthesis,': [129, 170, 421, 462, 3816], 'cells': [130, 185, 422, 478, 1038, 1046, 1279, 1382, 1395, 1414, 1464, 1566, 1690, 2330, 2409, 2475, 2647, 2752, 2766, 3018, 4368], 'were': [131, 247, 423, 540, 1383, 1396, 1415, 1443, 1477, 1487, 1521, 1567, 1637, 1710, 1769, 1836, 1847, 2009, 2024, 2036, 2055, 2119, 2156, 2166, 2179, 2186, 2192, 2211, 2356, 2410, 2476, 2598, 2648, 2701, 2825, 2833, 2874, 2891, 2907, 2917, 2927, 3835], 'labeled': [132, 424, 2600], 'with': [133, 186, 425, 479, 685, 741, 748, 1047, 1070, 1116, 1404, 1429, 1445, 1569, 1639, 1696, 1849, 2057, 2122, 2196, 2213, 2250, 2274, 2292, 2380, 2412, 2442, 2478, 2548, 2601, 2622, 2630, 2827, 2884, 2909, 3067, 3168, 3171, 3242, 3674, 3679, 3796, 3844, 4040, 4255, 4393, 4407], '[35S]methionine': [134, 426, 1697, 2602, 2676, 2709, 2728], 'immunoprecipitated.': [139, 431, 2609], 'synthetic': [141, 433, 746, 1675, 2574, 2592, 2616, 3494], 'rate': [142, 434, 747, 1676, 2575, 2617, 3495, 3721, 3805, 3814], 'treatment.': [149, 164, 441, 456, 2234, 2550, 2886, 2948, 2990], 'Western': [150, 202, 442, 495, 2039, 2654, 2836, 2920, 3000, 3864], 'blot': [151, 443, 2040, 2492, 2523, 2655], 'analysis': [152, 444, 2041], 'cell': [154, 446, 1590, 1672, 1986, 2002, 2641, 2831, 2915, 3688], 'lysates': [155, 447, 2008, 2642, 2832, 2916], 'indicated': [156, 448, 1447, 2418], 'decrease': [158, 167, 450, 459, 1360, 2240, 2458, 2470, 2556, 2560, 2572, 2686, 2745, 2759, 2790, 2797, 2993, 3009, 3684, 4308, 4317, 4350, 4632], 'mass': [161, 453, 2664], 'Despite': [165, 457], 'this': [166, 458, 1326, 1587, 3134, 3506, 3525, 3657, 4340, 4672], 'there': [171, 463, 700, 2236, 2700, 2741, 2926, 2977, 3276, 3484], 'no': [173, 465, 749, 2238, 2295, 2499, 2979, 3486, 3650], 'change': [174, 466, 750, 2547, 2580, 2981, 3487, 3652], 'mRNA': [177, 469, 817, 2473, 2504, 2511, 2530, 2544, 3270, 3490], 'TPA-treated': [180, 472, 1684, 2329, 2386, 2596, 2646, 2672, 2738, 2751, 2765, 2785], 'cells.Long': [181], 'down-regulate': [191, 484, 1120], 'PKC.': [192, 485, 890], 'assess': [194, 235, 487, 528, 2635], 'involvement': [196, 489, 989], 'different': [199, 492, 3199], 'isoforms,': [201, 218, 494, 511, 2822, 2996], 'blotting': [203, 496], 'performed.': [205, 498], 'α,': [213, 506, 2849, 2870], 'β,': [214, 507, 2850], 'δ,': [215, 508, 2851, 2871], 'ε': [217, 510, 2853, 2873], 'whereas': [219, 512, 3273], 'λ,': [221, 514, 2879], 'θ,': [222, 515], 'ζ,': [223, 516], 'μ,': [224, 517, 2878], 'ι,': [225, 518], 'γ': [227, 520, 2890], 'remained': [228, 521, 2512, 2882], 'unchanged': [229, 522, 2883], 'or': [230, 523, 1353, 2135, 2578, 2690, 3282, 3870, 4599], 'minimally.': [232, 525], 'directly': [234, 527, 3048, 3841], 'inhibition,': [240, 533], 'inhibitors': [242, 253, 535, 546, 1472, 3875], '(calphostin': [243, 536], 'staurosporine)': [246, 539], 'rapidly': [257, 550], '(within': [258, 551], '60': [259, 552, 2246, 3089], 'min).': [260, 553], 'Thus,': [261, 554, 2757, 2991, 3866], 'activation': [262, 555, 896, 984, 1057, 1332, 3584, 4032, 4260], 'did': [265, 558, 1348, 2545, 2554, 3900, 4641], 'but': [269, 562, 2365, 3492], 'resulted': [273, 566, 1055, 1357, 2467, 2794, 2862, 3818, 3848, 4257, 4629], 'synthesis': [277, 570, 2748, 2762], 'translation,': [281, 574, 2689, 2800, 3281, 4635], 'indicating': [282, 575, 3879], 'constitutive': [284, 577, 3912, 4655], 'role': [285, 578, 977, 1372, 3889, 3913, 4096, 4172, 4213], 'gene': [290, 583, 4218], 'expression.': [291, 584, 4564, 4616], 'cells.': [473, 2373, 3069], 'Long': [474, 3676], 'Lipoprotein': [585], '1The': [588], 'abbreviations': [589], 'used': [590, 2109, 2167], 'are:LPL,': [591], 'lipase;': [593], 'PKC,': [594, 3115, 3522, 4559], 'C;': [597], 'DAG,': [598, 892, 3564, 4598], 'diacylglycerol;': [599], 'TPA,': [600, 2253, 2383, 2408, 2828, 2904, 2912, 3073, 3555, 3592], '13-acetate;': [603], 'PAGE,': [604], 'polyacrylamide': [605], 'gel': [606], 'electrophoresis;': [607], 'FFA,': [608], 'free': [609, 1666], 'fatty': [610, 1667], 'acid.': [611], 'central': [614], 'enzyme': [615], 'lipid': [617, 3226], 'metabolism': [618], 'that': [619, 1245, 1367, 2788, 2868, 3257, 3510, 3524, 3646, 3795, 3827, 3880, 3907, 3963, 3972, 4014, 4166, 4189, 4344, 4391, 4552, 4595, 4622, 4648, 4670], 'expressed': [621, 1662, 2204], 'primarily': [622], 'adipose': [624, 681, 903, 3225, 4401], 'tissue': [625, 682, 904, 1237, 4402], 'muscle': [627], '(1Eckel': [628], 'R.H.': [629], 'N.': [630, 1815], 'Engl.': [631], 'J.': [632, 769, 831, 1135, 1220, 1222, 1301, 1540, 1624, 1754, 1788, 1891, 1951, 1976, 3318, 3338, 3360, 3379, 3400, 3444, 3468, 3601, 3605, 3635, 3691, 3693, 3695, 3735, 3755, 3928, 3949, 4133, 4236, 4327, 4448, 4472, 4489, 4517, 4521], 'Med.': [633], '1989;': [634, 3321, 3612, 3696, 4528], '320:': [635], '1060-1068Crossref': [636], 'PubMed': [637, 670, 715, 737, 778, 837, 869, 926, 950, 971, 1024, 1091, 1164, 1226, 1307, 1320, 1551, 1607, 1633, 1762, 1797, 1821, 1868, 1900, 3038, 3211, 3295, 3327, 3347, 3369, 3385, 3406, 3424, 3453, 3474, 3578, 3615, 3639, 3699, 3740, 3766, 3789, 3934, 3955, 4006, 4073, 4144, 4242, 4336, 4377, 4437, 4457, 4478, 4495, 4531, 4546], 'Scopus': [638, 671, 716, 838, 870, 927, 951, 972, 1025, 1092, 1165, 1227, 1308, 1321, 1552, 1608, 1763, 1822, 1869, 3039, 3212, 3296, 3386, 3407, 3425, 3475, 3579, 3616, 3640, 3700, 3741, 3767, 3790, 3935, 3956, 4074, 4145, 4243, 4378, 4479, 4496, 4532], '(878)': [639], 'Google': [640, 673, 718, 738, 779, 840, 872, 929, 953, 974, 1027, 1094, 1144, 1167, 1229, 1310, 1323, 1554, 1610, 1634, 1765, 1798, 1824, 1871, 1901, 3041, 3214, 3298, 3328, 3348, 3370, 3388, 3409, 3427, 3454, 3477, 3581, 3618, 3642, 3702, 3743, 3769, 3792, 3937, 3958, 4007, 4076, 4147, 4245, 4337, 4380, 4438, 4458, 4481, 4498, 4534, 4547], 'Scholar).': [641, 674, 780, 841, 873, 975, 1028, 1168, 1230, 1324, 1555, 1611, 1635, 1766, 1799, 1825, 1921, 1984, 3215, 3299, 3478, 3582, 3643, 3703, 3770, 4077, 4148, 4246, 4338, 4499, 4548], 'complex': [648], 'may': [651, 4016, 4168, 4200, 4292, 4383, 4660], 'occur': [652, 4392], 'transcriptional,': [655], 'translational,': [656], 'posttranslational': [658, 2583, 3283], 'levels': [659, 818, 2505, 3267, 3882, 4503], '(2Enerbäck': [660, 3201, 3285], 'S.': [661, 918, 1013, 1086, 1159, 1296, 3202, 3286, 3754], 'Gimble': [662, 3203, 3287], 'J.M.': [663, 764, 1529, 1781, 1884, 3204, 3288, 3315, 3335, 3357, 3395, 3412, 3439, 3944, 4443], 'Biochim.': [664, 3205, 3289], 'Biophys.': [665, 863, 3206, 3290], 'Acta.': [666, 3207, 3291], '1993;': [667, 3208, 3292, 4003, 4070], '1169:': [668, 3209, 3293], '107-125Crossref': [669, 3210, 3294], '(182)': [672, 3213, 3297], 'patients': [684, 4404], 'diabetes.': [686, 4394], 'After': [687, 1585, 2374], 'control': [690, 1682, 2384, 2533, 2594, 2736, 2783, 3068, 3435, 4416], 'hyperglycemia': [691, 981], 'both': [693, 812, 2668, 2735, 2782, 4408], 'type': [694, 697], 'I': [695], 'II': [698], 'diabetes,': [699, 4412, 4584], 'an': [702, 742, 2692, 2804, 2953, 3243, 3588, 3969, 4046, 4259, 4279, 4356, 4612, 4662], '(3Taskinen': [707], 'M.-R.': [708], 'Nikkilä': [709], 'E.A.': [710], 'Diabetologia.': [711], '1979;': [712], '17:': [713, 924, 1628], '351-357Crossref': [714], '(109)': [717], 'Scholar,': [719, 930, 954, 1145, 1311, 1902, 1968, 3349, 3389, 3410, 3455, 3619, 3744, 3938, 4439, 4459, 4482, 4535], '4Pfeifer': [720], 'M.A.': [721, 938, 4421], 'Brunzell': [722, 913, 933, 4422, 4487], 'J.D.': [723, 725, 914, 934, 4423, 4425, 4488], 'Best': [724, 4424], 'Judzewitsch': [726, 4426], 'R.G.': [727, 4427], 'Halter': [728, 4428], 'J.B.': [729, 4429], 'Porte': [730, 4430], 'Jr.,': [731, 4431], 'D.': [732, 1153, 1294, 1313, 1955, 3376, 3603, 3607, 3925, 4231, 4432, 4519, 4523], 'Diabetes.': [733, 967, 1020, 1316, 3034, 4433, 4542], '1983;': [734, 1088, 4434], '32:': [735, 4435], '525-531Crossref': [736, 4436], 'Scholar),': [739, 1095, 3042, 3329, 3371, 3428, 3959, 4008, 4381], 'along': [740], 'mRNA,': [753, 807, 2558], 'suggesting': [754], 'level': [758, 3533], 'translation': [760, 3303, 3965, 4019, 4194], '(5Simsolo': [761, 3436], 'R.B.': [762, 1535, 3416, 3437, 4441], 'Ong': [763, 1528, 1753, 1975, 3334, 3356, 3394, 3438, 3943, 4442], 'Saffari': [765, 3413, 3440, 4444], 'B.': [766, 855, 1009, 3333, 3414, 3441, 4235, 4445], 'Kern': [767, 959, 1538, 1751, 1786, 1889, 1905, 1977, 3316, 3336, 3377, 3398, 3417, 3442, 3926, 3947, 4446], 'P.A.': [768, 1539, 1752, 1787, 1890, 1906, 1978, 3317, 3337, 3351, 3378, 3399, 3418, 3443, 3927, 3948, 4447, 4537], 'Lipid': [770, 1625, 3339, 3361, 3445, 4449], 'Res.': [771, 864, 1626, 3340, 3362, 3446, 4450], '1992;': [772, 834, 3341, 3421, 3447, 3471, 3636, 4451, 4475], '33:': [773, 3342, 3448, 4452], '89-95Abstract': [774, 3449, 4453], 'Full': [775, 1141, 1546, 1548, 1630, 1794, 1897, 3324, 3344, 3366, 3450, 3761, 3763, 4139, 4141, 4333, 4454], 'Text': [776, 1142, 1547, 1549, 1631, 1795, 1898, 3325, 3345, 3367, 3451, 3762, 3764, 4140, 4142, 4334, 4455], 'PDF': [777, 1143, 1550, 1632, 1796, 1899, 3326, 3346, 3368, 3452, 3765, 4143, 4335, 4456], 'Similar': [781], 'observations': [782], 'have': [783, 1175, 1930, 2681, 3255, 3961, 3993, 4620], 'been': [784, 898, 994, 1176, 1661, 2682, 3305, 3710, 4122], 'made': [785, 1488], 'experimental': [787], 'models': [788, 999], 'insulin-deficient': [790, 799, 901, 4409], 'diabetic': [791, 902, 1258, 1275], 'rats.': [792], 'Whereas': [793], 'insulin': [796, 809, 844, 991, 1437, 4221, 4282, 4290, 4302, 4310, 4319], 'rats': [800], 'increased': [801, 811, 1266, 2441, 3167, 3720, 4417], 'more': [804, 3111], 'than': [805, 1108, 2303, 2370, 3812], 'prolonged': [808, 1114, 2814, 3014, 3797, 4251], '(6Tavangar': [819], 'K.': [820, 1005, 1910, 3457, 3627, 3752, 4229, 4461], 'Murata': [821, 3458, 4462], 'Y.': [822, 1300, 3459, 3748, 4463], 'Pedersen': [823, 3460, 4464], 'M.E.': [824, 1750, 3461, 4465], 'Goers': [825, 3462, 4466], 'J.F.': [826, 1748, 3463, 4467], 'Hoffman': [827, 3464, 3600, 4468, 4516], 'A.R.': [828, 3465, 4469], 'Kraemer': [829, 3466, 4470], 'F.B.': [830, 3467, 4471], 'Clin.': [832, 3401, 3469, 3950, 4473, 4490], 'Invest.': [833, 3402, 3470, 3951, 4474, 4491], '90:': [835, 3472, 4476], '1672-1678Crossref': [836, 3473, 4477], '(53)': [839, 1309, 3476, 4480], 'Glucose': [842], 'modulate': [845], '(PKC)': [849], '(7Draznin': [854], 'Leitner': [856, 4232], 'J.W.': [857], 'Sussman': [858], 'K.E.': [859], 'Sherman': [860], 'N.A.': [861], 'Biochem.': [862, 1758, 1817, 1963, 3634, 3694, 3736], 'Commun.': [865], '1988;': [866, 1161, 1791, 1894], '156:': [867], '570-575Crossref': [868], '(82)': [871, 3701], 'Hyperglycemia': [874], 'cellular': [879, 1128, 1708], 'diacylglycerol': [880], '(DAG),': [881], 'turn': [884], 'natural': [887, 3566], 'activator': [888], 'Elevated': [891, 4500], 'resulting': [893, 3500], 'has': [897, 993, 1234, 1660, 3304, 3709, 4121], 'identified': [899], '(8Rouis': [905], 'M.': [906, 1288, 1298, 1533, 3725], 'Dugi': [907], 'K.A.': [908], 'Previato': [909], 'L.': [910, 1015, 1957, 3731, 4128], 'Patterson': [911], 'A.P.': [912], 'Brewer': [915], 'H.B.': [916], 'Santamarina-Fojo': [917], 'Arterioscler.': [919, 943], 'Thromb.': [920, 944], 'Vasc.': [921, 945], 'Biol.': [922, 946, 1136, 1541, 1789, 1892, 3319, 3380, 3756, 3929, 4002, 4134, 4237, 4328], '1997;': [923, 1223, 3382, 3931, 4136], '1400-1406Crossref': [925], '(64)': [928, 1764], '9Wijsman': [931], 'E.M.': [932], 'Jarvik': [935], 'G.P.': [936], 'Austin': [937], 'Motulsky': [939], 'A.G.': [940], 'Deeb': [941], 'S.S.': [942], '1998;': [947, 1317], '18:': [948], '215-226Crossref': [949], '(42)': [952], '10Xia': [955], 'P.': [956, 1621, 1813], 'Inoguchi': [957], 'T.': [958, 1292, 3025, 3029, 3599, 4515], 'T.S.': [960], 'Engerman': [961], 'R.L.': [962], 'Oates': [963], 'P.J.': [964, 3733], 'King': [965, 1314], 'G.L.': [966, 1315], '1994;': [968, 1965, 1980, 3737, 3786, 4330], '43:': [969], '1122-1129Crossref': [970], '(0)': [973], 'hyperinsulinemia': [979], 'isoforms': [987, 1172, 1247, 1263, 2869, 2877, 2933, 2959, 3862], 'resistance': [992], 'various': [997, 1833], 'animal': [998], '(11Avignon': [1002], 'A.': [1003, 1087, 1160, 1531, 1537, 1949, 1974, 3355, 3391, 3746, 3940], 'Yamada': [1004], 'Zhou': [1006], 'X.': [1007], 'Spencer': [1008], 'Cardona': [1010], 'O.': [1011, 4130, 4484], 'Saba-Siddique': [1012], 'Galloway': [1014], 'Standaert': [1016, 3622], 'M.L.': [1017, 3623, 3779], 'Farese': [1018, 3032, 3608, 4524], 'R.V.': [1019, 3033, 3621], '1996;': [1021, 3363, 3575, 4239, 4374], '45:': [1022], '1396-1404Crossref': [1023], '(140)': [1026], 'present': [1031], 'soluble': [1034], 'cytoplasmic': [1035], 'fraction': [1036, 2316], 'prior': [1039], 'stimulation,': [1041], 'ester': [1050, 1118], 'translocation': [1059], 'membrane.': [1064], 'interacting': [1069], 'DAG': [1072, 4508, 4556], 'binding': [1073, 4156, 4203], 'site': [1074], '(12Niedel': [1075], 'J.E.': [1076], 'Kuhn': [1077], 'L.J.': [1078], 'Vandenbark': [1079], 'G.R.': [1080], 'Proc.': [1081, 1154], 'Natl.': [1082, 1155], 'Acad.': [1083, 1156], 'Sci.': [1084, 1157], 'U.': [1085, 1149, 1158, 3783], '80:': [1089], '36-40Crossref': [1090], '(1061)': [1093], 'although': [1096, 4636], 'degree': [1098, 2369], 'much': [1106, 2938], 'greater': [1107, 2939], 'induction': [1110], 'DAG.': [1112], 'However,': [1113, 1260], 'can': [1119, 1179, 3557], 'depleting': [1127], '(13Ballester': [1131], 'R.': [1132, 1151, 1290, 1972, 3359, 3609, 4060, 4525], 'Rosen': [1133], 'O.M.': [1134], 'Chem.': [1137, 1542, 1790, 1893, 3320, 3381, 3757, 3930, 4135, 4238, 4329], '1995;': [1138, 1304, 1543, 3403, 3758, 3952], '260:': [1139], '15194-15199Abstract': [1140], '14Borner': [1146], 'C.': [1147, 2077, 3727, 3729, 4227, 4679], 'Eppenberger': [1148], 'Wyss': [1150], 'Fabbro': [1152], '85:': [1162], '2110-2114Crossref': [1163], '(58)': [1166], 'eleven': [1170], 'related': [1171, 4602], 'described': [1177, 1524, 1618, 1745, 1778, 1879, 2005, 2678, 2973, 4123], 'be': [1180, 4181, 4384], 'classified': [1181], 'into': [1182, 2730, 2781], 'three': [1183], 'subgroups,': [1184], 'depending': [1185], 'requirement': [1188], 'phospholipid,': [1191], 'calcium': [1193], 'activation.': [1195], 'These': [1196, 1364, 4645], 'isoenzymes': [1197], 'are': [1198, 1251, 1264, 2203, 3271, 4190, 4579], 'characterized': [1199], 'differences': [1201], 'their': [1203, 4155, 4158], 'four': [1204], 'domains,': [1205, 1208, 1215], 'regulatory': [1207, 3990, 4187, 4358], 'C1': [1209], 'C2,': [1211], 'catalytic': [1214, 1613], 'C3': [1216], 'C4': [1218], '(15Hofmann': [1219], 'FASEB': [1221], '11:': [1224], '649-669Crossref': [1225], '(335)': [1228], 'Each': [1231], 'isoform': [1233, 2150], 'distinct': [1236], 'distribution': [1238], 'physiological': [1240, 3881, 4048], 'function.': [1241], 'Recent': [1242], 'studies': [1243, 1923, 3254, 3714, 3921], 'indicate': [1244, 2787], 'β': [1248], 'δ': [1250, 2962], 'activated': [1252, 1497], 'preferentially': [1253], 'vasculature': [1256], 'animals.': [1259], 'other': [1261, 3274, 4109, 4215], 'also': [1265, 2325, 2525, 3855], 'glomeruli': [1269], 'retinal': [1271], 'tissues': [1272], 'isolated': [1273], 'from': [1274, 1385, 1479, 1803, 1831, 2086, 2101, 2158, 2468, 2569, 2643, 2795, 2803], 'animals': [1276, 4406], 'cultured': [1280], 'presence': [1283], 'high': [1285], '(16Haneda': [1287], 'Kikkawa': [1289], 'Sugimoto': [1291], 'Koya': [1293], 'Araki': [1295], 'Togawa': [1297], 'Shigeta': [1299], 'Diabetes': [1302], 'Complicat.': [1303], '9:': [1305], '246-248Crossref': [1306], '17Koya': [1312], '47:': [1318], '859-866Crossref': [1319], '(1181)': [1322], 'In': [1325, 2345, 2949, 3070, 3479, 3505, 3918, 4339, 4617], 'study,': [1327, 4341], 'depletion': [1334, 1352, 3520, 3821, 3858, 3867, 4346, 4624], 'examined': [1341, 3044], 'translation.': [1363, 3535, 4353], 'data': [1365, 2202, 3905, 4646], 'suggest': [1366, 3906, 4647], 'plays': [1369, 4210], 'vital': [1371, 3888, 4212], 'expression': [1375, 2540, 2819, 2846, 2957, 3511, 4219, 4656], 'obtained': [1384, 2100], 'Dr.': [1386, 2087], 'Howard': [1387], 'Green': [1388], '(Harvard': [1389], 'Medical': [1390], 'School,': [1391], 'Boston,': [1392], 'MA).': [1393], 'maintained': [1397], "Dulbecco's": [1399, 1575], 'modified': [1400, 1576], "Eagle's": [1401, 1577], 'medium,': [1402], 'supplemented': [1403], '10%': [1405, 1430, 1772, 2027], 'calf': [1406, 1432], 'serum': [1407, 1433, 1646], '(Life': [1408], 'Technologies,': [1409], 'Inc.).': [1410], 'For': [1411, 3771], 'experiments,': [1412], 'grown': [1416], 'confluence': [1418], '12-well': [1420], 'cluster': [1421], 'plates,': [1422], 'differentiated': [1424], 'incubation': [1426], 'medium': [1428, 1503, 1562, 1578], 'fetal': [1431], 'containing': [1434, 1642, 1715, 2030, 2125], '5–7': [1439], 'days.': [1440], 'Differentiated': [1441], 'treated': [1444, 1568, 2056, 2212, 2411, 2477, 2826, 2908], 'dissolved': [1451], '1': [1453, 1458, 2421, 3142], 'μl': [1454], 'Me2SO': [1456, 1490], 'ml': [1459], 'culture': [1461, 1502], 'medium.': [1462], 'Control': [1463], 'received': [1465], 'same': [1467, 2514, 2522, 3005], 'amount': [1468], 'Me2SO.': [1470], 'staurosporine': [1473, 3058, 3085], 'calphostin': [1475, 1483, 3106, 3131, 3144, 3165, 3179], 'purchased': [1478, 2157], 'Calbiochem.': [1480], 'Staurosporine': [1481], 'stock': [1485], 'solutions': [1486], '1,000×': [1492], 'concentration.': [1493], 'Calphostin': [1494], 'exposure': [1505], 'light': [1507], '10': [1509, 1570], 'min': [1510, 1581, 1655, 2017, 2247, 2965, 3090, 3154, 3597], 'as': [1511, 1523, 1617, 1647, 1663, 1777, 1878, 2205, 2506, 2531, 2628, 2997, 3007, 4081], 'recommended': [1512], 'manufacturer.': [1515], 'Heparin': [1516], 'releasable': [1517, 1559, 2227, 2315, 2362], 'extractable': [1519, 2321], 'prepared': [1522], 'previously': [1525, 1619, 1882], '(18Ranganathan': [1526], 'G.': [1527, 1904, 1970, 3353, 3374, 3397, 3923, 3946, 4056, 4058, 4066], 'Yukht': [1530, 1973, 3354], 'Saghizadeh': [1532], 'Simsolo': [1534, 3415], 'Pauer': [1536], '270:': [1544, 3759], '7149-7155Abstract': [1545], '(45)': [1553], 'measure': [1557], 'heparin': [1558, 1573, 2226, 2314, 2361], 'aspirated,': [1564, 1704], 'units/ml': [1571], '45': [1580, 1654], '37': [1583], '°C.': [1584], 'collecting': [1586], 'fraction,': [1588], 'layer': [1591, 1987], 'extracted': [1593, 1711, 1802, 1999], 'detergent-containing': [1596], 'buffer': [1597, 1714, 2004, 2124], '(19Iverius': [1598], 'P.H.': [1599, 4486], 'Ostlund-Lindqvist': [1600], 'A.M.': [1601], 'Methods': [1602], 'Enzymol.': [1603], '1986;': [1604], '129:': [1605], '691-704Crossref': [1606], '(81)': [1609], 'measured': [1616, 1680], '(20Nilsson-Ehle': [1620], 'Schotz': [1622, 1755, 1784, 1860, 1887], 'M.C.': [1623, 1756, 1785, 1861, 1888], '1976;': [1627], '536-541Abstract': [1629], 'Samples': [1636, 2029], 'incubated': [1638], 'emulsified': [1640], 'substrate': [1641, 4049, 4364], '[3H]triolein': [1643], 'human': [1645, 3801], 'source': [1649], 'apo': [1651], 'C-II': [1652], '37°.': [1657], 'nanomoles': [1664], 'acid': [1668], '(FFA)': [1669], 'released/hr/mg': [1670], 'protein.': [1673, 3824], 'pulse': [1687, 2599, 2710, 2774], 'labeling': [1688, 2711, 2775], 'specified': [1693], 'time': [1694, 2219, 2484, 2518, 2755, 3006, 3658], 'intervals': [1695], '(100': [1698], 'μCi/ml).': [1699], 'unincorporated': [1701], 'label': [1702], 'total': [1707, 1829, 1996, 2034, 2307, 2636, 2640, 2830, 2914], 'proteins': [1709, 3992, 4088, 4112, 4153, 4188], 'lysis': [1713, 2003], '50': [1716], 'mm': [1717, 1727, 1734, 2059, 2064], 'phosphate': [1718, 1992], 'buffer,': [1719], 'pH': [1720, 2061], '7.4,': [1721], '2%': [1722], 'deoxycholate,': [1723], '1%': [1724, 1842], 'SDS,': [1725], '20': [1726, 2058, 2128, 2772], 'phenylmethylsulfonyl': [1728], 'fluoride,': [1729], '2': [1730, 1733, 2935, 3158, 3177], 'mmleupeptin,': [1731], 'EDTA.': [1735], 'Labeled': [1736], 'immunoprecipitated': [1739], 'using': [1740, 1805, 1838, 2000, 2026, 2047, 2143, 2188, 2835, 2919, 3052, 3873], 'specific': [1742, 2151, 3112, 3845, 4363], 'polyclonal': [1743, 2079], 'antibodies': [1744, 2155, 2165], 'earlier': [1746, 1779, 2899], '(21Goers': [1747], 'Petersen': [1749], 'Anal.': [1757, 1816], '1987;': [1759, 1818, 1865], '166:': [1760], '27-35Crossref': [1761], 'Immunoprecipitated': [1767], 'samples': [1768], 'analyzed': [1770, 1837, 2649, 2834, 2918], 'SDS-PAGE': [1773], 'followed': [1774, 2486, 2719], 'autoradiography': [1776], '(22Ong': [1780, 1883], 'Kirchgessner': [1782, 1856, 1885], 'T.G.': [1783, 1857, 1886], '263:': [1792, 1895], '12933-12938Abstract': [1793, 1896], 'RNA': [1800, 1830, 1933, 2488, 4160], 'method': [1807], 'Chomczynski': [1809], 'Sacchi': [1811, 1814], '(23Chomczynski': [1812], '162:': [1819], '156-159Crossref': [1820], '(64426)': [1823], 'Equal': [1826], 'amounts': [1827], 'groups': [1835], '2.2': [1839], 'm': [1840], 'formaldehyde,': [1841], 'agarose': [1843], 'gels.': [1844], 'Northern': [1845, 2491], 'blots': [1846], 'probed': [1848, 2526], '32P-labeled': [1851], 'hLPL': [1852], 'cDNA': [1853, 1876], '(24Wion': [1854], 'K.L.': [1855], 'Lusis': [1858], 'A.J.': [1859, 3625], 'Lawn': [1862], 'R.M.': [1863], 'Science.': [1864], '235:': [1866], '1638-1641Crossref': [1867], '(375)': [1870], 'Scholar)': [1872, 3793], 'glyceraldehyde-3-phosphate': [1874, 2528, 2542], 'dehydrogenase': [1875, 2529, 2543], 'probe': [1877], 'us': [1881], '25Ranganathan': [1903], 'Doolittle': [1907], 'M.H.': [1908], 'Reue': [1909], 'Lipase': [1911], 'Phospholipase': [1913], 'Protocols.': [1914], 'Humana': [1915], 'Press,': [1916], 'Inc.,': [1917], 'Totowa,': [1918], 'NJ1999:': [1919], '329-336Google': [1920], 'Previous': [1922], 'involving': [1924], 'murine': [1925], 'including': [1927, 3312, 4089, 4512], 'two': [1932, 1943], 'species': [1934], '3.2': [1936], '3.6': [1938], 'kilobases': [1939], 'because': [1940], 'alternative': [1944], 'sites': [1945], 'polyadenylation': [1947], '(26Raisonnier': [1948], 'Etienne': [1950], 'Arnault': [1952], 'F.': [1953, 1961], 'Brault': [1954], 'Noe': [1956], 'Chuat': [1958], 'J.C.': [1959, 4126], 'Galibert': [1960], 'Comp.': [1962], 'Physiol.': [1964], ':': [1966], '385-398Google': [1967], '27Ranganathan': [1969], 'Davis': [1971, 3358, 3392, 3941], 'Circulation.': [1979], '(67th': [1981], 'session': [1982], '(abstr.))Google': [1983], 'rinsed': [1989], 'ice-cold': [1991], 'buffered': [1993], 'saline': [1994], 'above.': [2006], 'centrifuged': [2010], '1,500': [2012], '×': [2013], 'g': [2014], '15': [2016, 2031], 'separate': [2019], 'insoluble': [2021], 'debris.': [2022], 'Proteins': [2023], 'fractionated': [2025], 'SDS-PAGE.': [2028], 'μg': [2032], 'electrophoresed': [2037], 'transferred': [2043], 'onto': [2044], 'nitrocellulose': [2045], 'membranes': [2046], '300': [2048], 'mA': [2049], 'current': [2050], '2–3': [2052], 'h.': [2053, 3159], 'Membranes': [2054, 2118, 2178], 'Tris/HCl,': [2060], '7.6,': [2062], '150': [2063], 'NaCl,': [2065], '0.2%': [2066], 'Tween': [2067, 2127], '20,': [2068, 2714], '5%': [2070], 'nonfat': [2071], 'dry': [2072], 'milk': [2073], 'overnight': [2074, 2375, 2860], '4°': [2076], 'antibody': [2080, 2107, 2174], '(rabbit)': [2081], 'generous': [2084], 'gift': [2085], 'Ira': [2088], 'Goldberg': [2089], '(Columbia': [2090], 'University,': [2091], 'New': [2092], 'York,': [2093], 'NY).': [2094], 'Anti-rabbit': [2095], 'horseradish': [2096], 'peroxidase': [2097], 'conjugate': [2098], 'Sigma': [2102], 'Chemical': [2103], 'Company.': [2104], '1:2,000': [2111], 'dilution': [2112, 2170], 'secondary': [2115, 2136, 2154, 2173], '1:5,000.': [2117], 'washed': [2120], 'extensively': [2121], 'Tris': [2123], '0.1%': [2126], 'remove': [2130], 'excess': [2132], 'antibody.': [2137], 'detected': [2142, 2187], 'chemoluminescence': [2144], 'reagents': [2145], '(Amersham': [2146], 'Pharmacia': [2147], 'Biotech).': [2148], 'Transduction': [2159], 'Laboratories,': [2160], 'Lexington,': [2161], 'KY.': [2162], '1:1,000': [2169], '1:5,000': [2176], 'dilution.': [2177], 'washed,': [2180], 'bands': [2185], 'chemoluminescence.': [2189], 'All': [2190], 'experiments': [2191], 'performed': [2193, 2708], 'triplicate': [2195, 2197], 'wells': [2198], 'each,': [2200], 'mean': [2206], '±': [2207, 2278, 2283, 2333, 2338, 2391, 2395], 'S.E.': [2208], 'varying': [2218, 2483], 'intervals.': [2220, 2756], 'As': [2221, 2417, 2610, 2657, 2724, 2838, 2922, 2972, 3121], 'shown': [2222, 2507, 2611, 2658, 2725, 2839, 2923, 3122], 'Fig.': [2224, 2420, 2660, 2975], '1,': [2225, 2976], 'significant': [2239, 2980, 3651], 'during': [2243, 3228, 3656], 'first': [2245], 'began': [2256], 'diminish': [2258], '3': [2260, 2661], '80%': [2268], '(control,': [2276, 2331], '1.06': [2277], '0.1;': [2279, 2334], 'treated,': [2281, 2336], '0.158': [2282], '0.025': [2284], 'μmol': [2285, 2340], 'FFA/hr/mg': [2287, 2342], 'protein).': [2289, 2344], 'Overnight': [2290], 'had': [2294, 2498], 'additional': [2296], 'activity.': [2301, 3012, 3504, 3853, 3895, 4178, 4208], 'More': [2302], '75%': [2304, 3156], 'found': [2311], 'Total': [2320], '82%': [2327], '1.6': [2332], '0.280': [2337], '0.08': [2339], 'studying': [2348], 'adipocytes,': [2350, 3549], 'examined,': [2357], 'activity,': [2364, 3667, 3878, 4314], 'lesser': [2368], '44.6': [2390], '5.1': [2392], '31.1': [2394], '2.9': [2396], 'nmol': [2397], 'FFA/hr/106': [2399], 'cells,': [2400, 2739, 2786, 3803, 4511], 'respectively.': [2401], 'study': [2403, 2810, 3507], 'dose': [2405], 'response': [2406, 2463, 3308, 3431, 3590], 'increasing': [2413, 2443, 3169], 'concentrations': [2414, 3170], 'TPA.': [2416, 2453, 3675], 'B': [2422], 'dose-dependent': [2429], '30%.': [2438], 'levels,': [2474], 'intervals,': [2485], 'extraction': [2489], 'analysis.': [2493, 2656], 'Fig.2.': [2509], 'all': [2516, 2754, 2931, 3480], 'points': [2519], 'studied.': [2520], 'equal': [2535], 'loading': [2536, 4268], 'RNA.': [2538], 'Because': [2551, 3013, 3896], 'following': [2564], 'could': [2567, 2680, 4180], 'result': [2568], 'either': [2570], 'processing.': [2584], 'rate,': [2593], '30': [2604, 2964, 3153, 3596], 'min,': [2605, 2718], 'Fig.3': [2613], 'A,': [2614, 3125], '75–80%': [2621], 'compared': [2629, 3066], 'untreated': [2632], 'control.': [2633], 'immunoreactive': [2638], 'mass,': [2639], 'control,': [2644], 'B,': [2662], '6-': [2669], '16-h': [2671], 'lysates.': [2673], 'incorporation': [2677, 2729, 2780], 'above': [2679], 'due': [2683, 3718], 'degradation.': [2696, 2808], 'any': [2702], 'effects': [2703, 3830], 'degradation,': [2706], '10,': [2713], '30,': [2715], '40': [2717], 'immunoprecipitation': [2721], 'Fig.4,': [2727], 'linear': [2733, 2779], '50–60%': [2744], 'shorter': [2769], '(10': [2770], 'min)': [2773], 'times,': [2776], 'blots.': [2837, 2921], 'Fig.5,': [2841], 'within': [2854, 3088, 3595], 'further': [2865, 3097], 'decrease,': [2866], 'such': [2867, 4566], 'undetectable.': [2875], 'ζ': [2881], 'Isoforms': [2887], 'ι': [2888], 'detectable': [2893], 'examine': [2898], 'times': [2900, 3275], 'Fig.6,': [2925], 'small': [2928], 'decreases': [2929, 2940], '4': [2942], 'addition,': [2950], 'α': [2960, 4052], '(data': [2969, 3093], 'shown).': [2971, 3095], 'until': [2985], '2.5–3': [2986], 'demonstrated': [2998, 3256, 3306, 3794, 3856, 3962, 4343, 4621], 'blotting,': [3001], 'deplete': [3022], '(28Ishizuka': [3024], 'Cooper': [3026, 3602, 3632, 4518], 'D.R.': [3027, 3633, 4132], 'Arnold': [3028, 3628], 'Hernandez': [3030, 3630], 'H.': [3031, 3631, 4062, 4064], '1991;': [3035], '40:': [3036], '1274-1281Crossref': [3037], '(35)': [3040, 3387, 3408, 3426, 3936, 3957], 'inhibiting': [3049], 'inhibitors.': [3054, 3846], '(1': [3059], 'μm)': [3060], '50%,': [3065], 'contrast': [3071], 'required': [3075], 'several': [3076, 3310, 3687, 3713, 3860], 'hours': [3077], 'inhibit': [3079, 3224, 4206], 'demonstrate': [3098, 3826], 'C,': [3107, 3132, 3145], 'inhibitor': [3113], 'Fig.7': [3124], 'quickly.': [3137], 'Following': [3138], 'μm': [3143, 3178], '30%': [3151], 'Inhibition': [3160], '(Fig.7': [3181], 'B).': [3182], 'hydrolyzes': [3184], 'triglyceride': [3186], 'core': [3187], 'lipoproteins': [3189], 'subject': [3192], 'number': [3197, 3252], 'hormones': [3200], 'physiologic': [3217], 'regulators': [3218], 'include': [3221], 'catecholamines,': [3222, 3976], 'accumulation': [3227], 'periods': [3229], 'active': [3231, 3884], 'lipolysis': [3232, 3246], '(e.g.': [3233, 3247], 'fasting),': [3234], 'insulin,': [3236], 'stimulates': [3238, 4504], 'concert': [3241], 'meal).': [3250], 'A': [3251], 'complex.': [3263], 'Under': [3264], 'some': [3265, 4601], 'conditions,': [3266, 3311], 'regulated,': [3272], 'processing': [3284], 'Regulation': [3300], '(29Ong': [3314], '264:': [3322], '3177-3182Abstract': [3323], 'thyroid': [3330], 'hormone': [3331], '(30Saffari': [3332], '241-249Abstract': [3343], '31Kern': [3350], 'Ranganathan': [3352, 3396, 3945], '37:': [3364], '2332-2340Abstract': [3365], 'epinephrine': [3372], '(32Ranganathan': [3373, 3922], 'Vu': [3375, 3924], '272:': [3383, 3932, 4137], '2515-2519Crossref': [3384, 3933], '33Yukht': [3390, 3939], 'R.C.': [3393, 3942], '96:': [3404, 3953], '2438-2444Crossref': [3405, 3954], '34Ong': [3411], 'Mol.': [3419, 3572, 4000, 4371], 'Endocrinol.': [3420, 3574, 4373], '6:': [3422], '61-69Crossref': [3423], 'improved': [3433, 4414], '6Tavangar': [3456, 4460], 'these': [3482, 4152], 'instances,': [3483], 'expression,': [3491], 'altered,': [3499], 'report': [3509], 'takes': [3529], 'place': [3530], 'mimic': [3558], 'part': [3560], 'ligand': [3567], '(35Liu': [3570, 4369], 'J.P.': [3571, 4370], 'Cell.': [3573, 4001, 4372], '116:': [3576, 4375], '1-29Crossref': [3577, 4376], '(213)': [3580, 4379], 'immediate': [3589], 'occurs': [3594], '(36Ishizuka': [3598, 4514], 'Watson': [3604, 4520], 'Pushkin': [3606, 4522], 'FEBS': [3610, 3784, 4526], 'Lett.': [3611, 3785, 4527], '249:': [3613, 4529], '234-238Crossref': [3614, 4530], '(55)': [3617, 4533], '37Farese': [3620], 'Francois': [3624], 'Ways': [3626], 'T.P.': [3629], '288:': [3637], '319-323Crossref': [3638], '(72)': [3641, 4146], 'We': [3644, 3854, 4675], 'caused': [3649, 3836], 'interval.': [3659], 'however,': [3668, 4585], 'evident': [3670], 'longer': [3672], 'types': [3689], '(38Adams': [3690], 'Gullick': [3692], '257:': [3697], '905-911Crossref': [3698], 'Phorbol': [3704, 4027], 'ester-induced': [3705], 'down-regulation': [3706, 4607], 'documented': [3711], 'mainly': [3717], 'degradation': [3723, 3807], '(39Junco': [3724], 'Webster': [3726], 'Crawford': [3728], 'Bosca': [3730], 'Parker': [3732], 'Eur.': [3734], '223:': [3738], '259-263Crossref': [3739], '(30)': [3742], '40Eto': [3745], 'Akita': [3747], 'Saido': [3749], 'T.C.': [3750], 'Suzuki': [3751], 'Kawashima': [3753], '25115-25120Abstract': [3760], '(84)': [3768], 'example,': [3772], 'Shea': [3773], 'et': [3774], 'al.': [3775], '(41Shea': [3776], 'T.B.': [3777], 'Beermann': [3778], 'Griffin': [3780], 'W.R.': [3781], 'Leli': [3782], '350:': [3787], '223-229Crossref': [3788], '(52)': [3791], 'neuroblastoma': [3802], 'PKC-α': [3809], 'faster': [3811], 'depletion,': [3839], 'This': [3847], 'blotting.': [3865], 'direct': [3871], 'play': [3886, 3910, 4169], 'stimulate': [3902], 'our': [3904, 3919], 'must': [3909], 'maintain': [3915, 4562], 'synthesis.': [3917], 'previous': [3920], 'regulated': [3967], 'RNA-binding': [3970, 3991, 4111], 'stimulated': [3974], 'binds': [3978], '3′-untranslated': [3981], 'region': [3982], 'mRNA.': [3986], 'Other': [3987], 'examples': [3988], 'phosphoproteins': [3995], '(42Kwon': [3996], 'Y.K.': [3997], 'Hecht': [3998], 'N.B.': [3999], '13:': [4004], '6547-6557Crossref': [4005], 'thus': [4010], 'it': [4011, 4592], 'possible': [4013, 4165, 4594], 'alter': [4017], 'through': [4020], 'phosphorylation': [4022, 4030, 4101, 4150, 4185, 4295, 4365], 'intermediate.': [4026], 'esters': [4028], 'trigger': [4029], 'RAF1,': [4034], '75-kDa': [4038], 'phosphoprotein': [4039], 'intrinsic': [4041], 'important': [4047, 4357, 4663, 4673], '(43Kolch': [4053], 'W.': [4054, 4233, 4683], 'Heidecker': [4055], 'Kochs': [4057], 'Hummel': [4059], 'Vahidi': [4061], 'Mischak': [4063], 'Finkenzeller': [4065], 'Marme': [4067], 'D.R.U.': [4068], 'Nature.': [4069], '364:': [4071], '249-252Crossref': [4072], '(1170)': [4075], 'Activated': [4078], 'RAF': [4079], 'functions': [4080], 'triggers': [4086], 'signaling': [4087, 4222, 4320], 'cytosolic': [4090], 'enzymes': [4091], 'like': [4092], 'S6': [4093], 'kinase.': [4094], 'neuromodulin': [4105], 'neurogranin,': [4107], 'nuclear': [4110], 'regulate': [4114, 4671], 'translational': [4115], 'initiation,': [4116], 'splicing': [4117], 'ribosomal': [4119], 'assembly': [4120], 'recently': [4124], '(44Deloulme': [4125], 'Prichard': [4127], 'Delattre': [4129], 'Storm': [4131], '27369-27377Abstract': [4138], 'inhibits': [4154], 'target': [4159], 'vitro.': [4162], 'It': [4163], 'similar': [4171], 'Depletion': [4197, 4247], 'dephosphorylate': [4201], 'aspects': [4216], '3T3-L1': [4224], '(45Schubert': [4226], 'Carel': [4228], 'DePaolo': [4230], 'Draznin': [4234], '271:': [4240], '15311-15314Crossref': [4241], '(22)': [4244], 'GTPase-activating': [4262], 'p21ras': [4266], 'GTP': [4267, 4271], '(substitution': [4269], 'GDP': [4273], 'p21ras),': [4275], 'results': [4277, 4305, 4347, 4604], 'alteration': [4280], 'action.': [4283], 'Another': [4284], 'alters': [4289], 'action': [4291], 'involve': [4293], 'serine': [4294], 'C-terminal': [4298], 'domain': [4299], 'receptor,': [4303], 'receptor': [4311], 'tyrosine': [4312], '(46Lewis': [4321], 'R.E.': [4322], 'Volle': [4323], 'D.J.': [4324], 'Sanderson': [4325], 'S.D.': [4326], '269:': [4331], '26259-26266Abstract': [4332], 'catalyzing': [4362], 'eukaryotic': [4367], 'relevant': [4385], 'changes': [4388], 'insulin-resistant': [4411], '(4Pfeifer': [4420], '5Simsolo': [4440], '47Pykalisto': [4483], 'Smith': [4485], '1975;': [4492], '56:': [4493], '1108-1116Crossref': [4494], '(230)': [4497], 'blood': [4501, 4577, 4587], 'production': [4506], 'many': [4510], '48Craven': [4536], 'Davidson': [4538], 'C.M.': [4539], 'DeRubertis': [4540], 'F.R.': [4541], '1990;': [4543], '39:': [4544], '667-674Crossref': [4545], 'One': [4549], 'would': [4550, 4557], 'expect': [4551], 'glucose-mediated': [4553], 'increases': [4554], 'activate': [4558], 'hence': [4561, 4611], 'Perhaps': [4565], 'case': [4569], 'under': [4570], 'normal': [4571, 4654], 'fasting/feeding': [4572], 'conditions': [4573], 'where': [4574, 4586], 'elevations': [4575], 'modest': [4580], 'transient.': [4582], 'With': [4583], 'chronically': [4590], 'elevated,': [4591], 'perhaps': [4600], 'mechanism,': [4603], 'summary,': [4618], 'affect': [4643], 'necessary': [4651], 'provide': [4661], 'link': [4664], 'signal': [4667], 'transduction': [4668], 'events': [4669], 'enzyme.': [4674], 'thank': [4676], 'Drs.': [4677], 'Timothy': [4678], 'Chambers': [4680], 'Steven': [4682], 'Barger': [4684], 'helpful': [4686], 'discussions,': [4687], 'Annadel': [4688], 'Fowler': [4689], 'technical': [4691], 'support,': [4692], 'Sarah': [4694], 'Joiner': [4695], 'assistance': [4697], 'preparation': [4700], 'manuscript.': [4703]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069610385', 'counts_by_year': [{'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T19:00:03.002117', 'created_date': '2016-06-24'}