Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2069278922', 'doi': 'https://doi.org/10.1093/emboj/16.6.1224', 'title': 'Tat is required for efficient HIV-1 reverse transcription', 'display_name': 'Tat is required for efficient HIV-1 reverse transcription', 'publication_year': 1997, 'publication_date': '1997-03-15', 'ids': {'openalex': 'https://openalex.org/W2069278922', 'doi': 'https://doi.org/10.1093/emboj/16.6.1224', 'mag': '2069278922', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9135139', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1169721'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/emboj/16.6.1224', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1093/emboj/16.6.1224', 'source': {'id': 'https://openalex.org/S127916151', 'display_name': 'The EMBO Journal', 'issn_l': '0261-4189', 'issn': ['0261-4189', '1460-2075'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1093/emboj/16.6.1224', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5017279608', 'display_name': 'David Harrich', 'orcid': 'https://orcid.org/0000-0003-3690-0150'}, 'institutions': [{'id': 'https://openalex.org/I867280407', 'display_name': 'The University of Texas Southwestern Medical Center', 'ror': 'https://ror.org/05byvp690', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I867280407']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'D. Harrich', 'raw_affiliation_strings': ['Division of Molecular Virology, Departments of Internal Medicine and Microbiology, University of Texas Southwestern Medical Center Dallas TX 75235‐8594 USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular Virology, Departments of Internal Medicine and Microbiology, University of Texas Southwestern Medical Center Dallas TX 75235‐8594 USA', 'institution_ids': ['https://openalex.org/I867280407']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5017279608'], 'corresponding_institution_ids': ['https://openalex.org/I867280407'], 'apc_list': {'value': 0, 'currency': 'USD', 'value_usd': 0, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.504, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 144, 'citation_normalized_percentile': {'value': 0.971389, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '16', 'issue': '6', 'first_page': '1224', 'last_page': '1235'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription', 'score': 0.53688085}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.92799294}, {'id': 'https://openalex.org/C156719811', 'wikidata': 'https://www.wikidata.org/wiki/Q28774', 'display_name': 'Reverse transcriptase', 'level': 4, 'score': 0.6750634}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.56936306}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.53688085}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.4584003}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.4338231}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.387375}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.19813523}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1657472}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015696', 'descriptor_name': 'Gene Products, tat', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004279', 'descriptor_name': 'DNA, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004279', 'descriptor_name': 'DNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003673', 'descriptor_name': 'Defective Viruses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003673', 'descriptor_name': 'Defective Viruses', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017353', 'descriptor_name': 'Gene Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015967', 'descriptor_name': 'Gene Expression Regulation, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015696', 'descriptor_name': 'Gene Products, tat', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015696', 'descriptor_name': 'Gene Products, tat', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015756', 'descriptor_name': 'Genes, tat', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005816', 'descriptor_name': 'Genetic Complementation Test', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054322', 'descriptor_name': 'tat Gene Products, Human Immunodeficiency Virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/emboj/16.6.1224', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1093/emboj/16.6.1224', 'source': {'id': 'https://openalex.org/S127916151', 'display_name': 'The EMBO Journal', 'issn_l': '0261-4189', 'issn': ['0261-4189', '1460-2075'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1169721', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9135139', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/emboj/16.6.1224', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1093/emboj/16.6.1224', 'source': {'id': 'https://openalex.org/S127916151', 'display_name': 'The EMBO Journal', 'issn_l': '0261-4189', 'issn': ['0261-4189', '1460-2075'], 'is_oa': True, 'is_in_doaj': True, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.81, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 78, 'referenced_works': ['https://openalex.org/W131142930', 'https://openalex.org/W1489114831', 'https://openalex.org/W1504782024', 'https://openalex.org/W1505853139', 'https://openalex.org/W1524005178', 'https://openalex.org/W1546915777', 'https://openalex.org/W1564738436', 'https://openalex.org/W1590989003', 'https://openalex.org/W1599509724', 'https://openalex.org/W1770347084', 'https://openalex.org/W1788807811', 'https://openalex.org/W1796915314', 'https://openalex.org/W1806273468', 'https://openalex.org/W1834412424', 'https://openalex.org/W1834993052', 'https://openalex.org/W1844569659', 'https://openalex.org/W1888137339', 'https://openalex.org/W1898538816', 'https://openalex.org/W1905921278', 'https://openalex.org/W1936470344', 'https://openalex.org/W1957422323', 'https://openalex.org/W1965804975', 'https://openalex.org/W1966425882', 'https://openalex.org/W1967446284', 'https://openalex.org/W1971057735', 'https://openalex.org/W1978229923', 'https://openalex.org/W1978539107', 'https://openalex.org/W1981500779', 'https://openalex.org/W1996827828', 'https://openalex.org/W2002261956', 'https://openalex.org/W2006659499', 'https://openalex.org/W2006800136', 'https://openalex.org/W2007534543', 'https://openalex.org/W201050536', 'https://openalex.org/W2013241878', 'https://openalex.org/W2013688988', 'https://openalex.org/W2014359186', 'https://openalex.org/W2016844359', 'https://openalex.org/W2019508559', 'https://openalex.org/W2020597127', 'https://openalex.org/W2027051533', 'https://openalex.org/W2027459341', 'https://openalex.org/W2028706937', 'https://openalex.org/W2033217413', 'https://openalex.org/W2037411475', 'https://openalex.org/W2044296969', 'https://openalex.org/W2048626266', 'https://openalex.org/W2060907425', 'https://openalex.org/W2061917886', 'https://openalex.org/W2069514224', 'https://openalex.org/W2070171685', 'https://openalex.org/W2072528655', 'https://openalex.org/W2072916562', 'https://openalex.org/W2073004681', 'https://openalex.org/W2073166118', 'https://openalex.org/W2074318459', 'https://openalex.org/W2076811542', 'https://openalex.org/W2084627994', 'https://openalex.org/W2086584161', 'https://openalex.org/W2088954468', 'https://openalex.org/W2089768147', 'https://openalex.org/W2090084965', 'https://openalex.org/W2098193092', 'https://openalex.org/W2098272959', 'https://openalex.org/W2105192976', 'https://openalex.org/W2127697961', 'https://openalex.org/W2151317983', 'https://openalex.org/W2154733328', 'https://openalex.org/W2154765648', 'https://openalex.org/W2163757819', 'https://openalex.org/W2166782710', 'https://openalex.org/W2170036028', 'https://openalex.org/W2170754061', 'https://openalex.org/W2258770630', 'https://openalex.org/W308040721', 'https://openalex.org/W4230243609', 'https://openalex.org/W4240483002', 'https://openalex.org/W89943134'], 'related_works': ['https://openalex.org/W4303983510', 'https://openalex.org/W2607725540', 'https://openalex.org/W2322280852', 'https://openalex.org/W2115295975', 'https://openalex.org/W2093866798', 'https://openalex.org/W2034458000', 'https://openalex.org/W2017060041', 'https://openalex.org/W2004698251', 'https://openalex.org/W2001725728', 'https://openalex.org/W1964676073'], 'abstract_inverted_index': None, 'abstract_inverted_index_v3': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069278922', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2025-01-26T00:04:10.939591', 'created_date': '2016-06-24'}