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'detergent-resistant': [92], 'microdomains': [93], '(DRMs)': [94], 'partially': [97], 'resistant': [98], 'proteinase': [100], 'K': [101], 'digestion.': [102], 'Although': [103], 'an': [104], 'untranslocated': [105], 'polyubiquitylated': [111], 'undergoes': [113], 'ER-associated': [114], 'degradation,': [115], 'proteasome': [117], 'responsible': [120], 'for': [121, 176], 'its': [125, 156, 164], 'misfolded': [126], 'suggesting': [128], 'that': [129, 172, 184], 'does': [131], 'role': [135, 190], 'pathogenesis': [138], 'inherited': [140], 'diseases.': [141], 'On': [142], 'contrary,': [144], 'impairment': [145], 'association': [148], 'DRMs': [150, 173], 'by': [151], 'cholesterol': [152], 'depletion': [153], 'accumulation': [157], 'ER': [160], 'substantially': [162], 'increases': [163], 'misfolding.': [165], 'These': [166], 'data': [167], 'support': [168], 'previous': [170], 'hypothesis': [171], 'important': [175], 'correct': [178], 'folding': [179], 'suggest': [183], 'they': [185], 'might': 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