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'both': [32, 134], 'by': [33, 52, 201, 212], 'the': [34, 46, 58, 72, 79, 89, 96, 113, 119, 127, 144, 184, 198, 207, 220], 'turnover': [35], 'complex': [37, 61, 208], 'intermediates': [41], 'sphingolipid': [43, 196, 204], 'biosynthesis.': [44], 'Usually,': [45], 'amounts': [47, 114], 'highly': [49], 'regulated;': [50], 'however,': [51], 'inhibiting': [53], 'ceramide': [54, 141, 155], 'synthase,': [55, 142], 'fumonisins': [56, 100, 194], 'block': [57], 'biosynthesis': [59], 'cause': [64, 87], 'sphinganine': [65], '(and': [66], 'sometimes': [67], 'sphingosine)': [68], 'to': [69], 'accumulate.': [70], 'Where': [71], 'mechanism': [73], 'has': [74], 'been': [75], 'studied': [76], 'most': [77], 'thoroughly,': [78], 'accumulation': [80], 'sphingoid': [82, 109], 'bases': [83, 110], 'is': [84, 133, 148, 163], 'primary': [86], 'toxicity': [90, 185], 'fumonisin': [92], 'B': [93], '(FB).': [94], 'Nonetheless,': [95], 'full': [97], 'effects': [98, 192, 222], 'probably': [101], 'involve': [102], 'many': [103], 'biochemical': [104], 'events.': [105], 'The': [106], 'elevations': [107], 'also': [111], 'affect': [112], 'other': [116], 'lipids,': [117], 'including': [118], '1-phosphates': [120], 'N-acetyl': [122], 'derivatives': [123], 'sphinganine.': [125], 'Furthermore,': [126], 'aminopentol': [128], 'backbone': [129], 'FB1': [131, 169], '(AP1)': [132], 'an': [135, 149], 'inhibitor': [136, 153], 'substrate': [139], 'resultant': [145], 'N-palmitoyl-AP1': [146], '(PAP1)': [147], 'even': [150], 'more': [151, 166], 'potent': [152], 'synthase': [156], '(presumably': [157], 'product': [160], 'analog).': [161], 'PAP1': [162], '10': [164], 'times': [165], 'toxic': [167], 'than': [168], 'or': [170], 'AP1': [171], 'HT-29': [173], 'cells': [174], 'culture,': [176], 'hence': [178], 'may': [179], 'play': [180], 'role': [182], 'nixtamalized': [187], 'fumonisins.': [188, 224], 'All': [189], 'these': [190], 'processes--the': [191], 'on': [195], 'metabolism,': [197, 205], 'pathways': [199], 'altered': [200], 'perturbation': [202], 'cellular': [209], 'behaviors': [210], 'regulated': [211], 'sphingolipids--must': [213], 'be': [214], 'borne': [215], 'mind': [217], 'when': [218], 'evaluating': [219], 'pathologic': [221]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069028107', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 19}, {'year': 2020, 'cited_by_count': 18}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 19}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 15}, {'year': 2015, 'cited_by_count': 14}, {'year': 2014, 'cited_by_count': 13}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 18}], 'updated_date': '2024-12-11T07:07:21.992916', 'created_date': '2016-06-24'}