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238, 406, 1203, 2079, 2665, 2900, 3795, 3887], 'regulated': [31, 239, 471, 3915], 'by': [32, 158, 240, 366, 475, 479, 560, 589, 1199, 1490, 1537, 1944, 2062, 2355, 2448, 2461, 2544, 2667, 2740, 2764, 2774, 2877, 2914, 2926, 3243, 3273, 3292, 3340, 3360, 3412, 3424, 3431, 3468, 3626, 3675, 3711, 3715, 3730, 3737, 3816, 3841, 3892, 3919, 3923, 4004, 4033], 'adhesion': [34, 242, 429, 476, 1415, 2073, 2085, 2100, 3289, 3470, 3920], 'to': [35, 66, 197, 243, 274, 405, 477, 831, 1202, 1460, 1567, 1947, 2083, 2101, 2339, 2375, 2457, 2467, 2486, 2488, 2520, 2556, 2714, 2883, 3158, 3290, 3405, 3482, 3888, 3921, 4276], 'extracellular': [36, 244, 416], 'matrix': [37, 245, 417], '(ECM)': [38, 246], 'even': [39, 247], 'absence': [42, 250, 2795], 'ligand.': [44, 252], 'We': [45, 253, 2963], 'investigated': [46, 254, 1395, 1410], 'pathway': [48, 144, 201, 256, 352, 409, 1397, 3390, 3495], 'involved': [49, 257, 1398, 2958], 'integrin-mediated': [51, 259, 1400, 2174, 2196], 'RTK': [52, 206, 260, 414, 1033, 1207, 3505], 'activation,': [53, 261], 'using': [54, 262], 'RON,': [55, 71, 129, 263, 279, 337, 1997, 2487, 3319, 3394], 'for': [58, 169, 202, 266, 377, 410, 834, 1610, 1971, 2262, 2395, 2542, 2731, 2803, 2875, 2897, 2920, 2982, 3043, 3051, 3111, 3190, 3215, 3219, 3318, 3393, 3403, 3475, 3500, 3553, 3620, 3662, 3698, 3799, 4279], 'macrophage-stimulating': [59, 267, 441, 1214], 'protein.': [60, 268], 'Adhesion': [61, 269], 'RON-expressing': [63, 271, 1431], 'epithelial': [64, 272, 1309, 1343, 1434, 1583, 3293, 3826], 'cells': [65, 98, 111, 126, 273, 306, 319, 334, 440, 469, 1310, 1344, 1435, 1462, 1545, 1959, 2218, 2235, 2309, 2408, 2423, 2475, 2499, 2517, 2527, 2550, 2671, 2680, 2691, 2820, 2846, 3000, 3028, 3227, 3238, 3263, 3280, 3294, 3521, 3582, 3605, 3709, 3827, 3913], 'ECM': [67, 119, 275, 327, 590, 1523, 1581, 1994, 2102, 2915, 3221, 3224, 3291, 3731, 3783, 3817, 3842, 3893, 4034], 'caused': [68, 276, 1463, 3298], 'phosphorylation': [69, 94, 124, 184, 277, 302, 332, 392, 1034, 1444, 1469, 1488, 1532, 1572, 1603, 2229, 2253, 2303, 2352, 2417, 2543, 2737, 2771, 2876, 2943, 3009, 3201, 3233, 3261, 3270, 3302, 3309, 3321, 3348, 3386, 3425, 3466, 3510, 3625, 3672, 3728, 3764, 3789, 3898], 'which': [72, 146, 172, 280, 354, 380, 2002, 2110, 2127, 2263, 2663, 3032, 3163, 3197, 3480, 3793], 'depended': [73, 186, 281, 394], 'on': [74, 88, 176, 187, 282, 296, 384, 395, 674, 846, 1036, 1342, 1416, 1436, 1530, 1570, 1601, 1877, 1996, 2547, 3054, 3205, 3226, 3368, 3409, 3512, 3535, 3578, 3811, 4118], 'kinase': [76, 192, 284, 400, 430, 451, 1038, 1450, 1471, 1574, 2045, 2074, 2162, 2675, 2906, 2951, 2978, 3047, 3107, 3169, 3217, 3326, 3338, 3358, 3487, 3518, 3776], 'activity': [77, 285, 599, 1039, 1099, 1419, 1451, 1472, 2907, 2979, 3048, 3108, 3170, 3218, 3327, 3339, 3359, 3398, 4043], 'both': [79, 151, 188, 287, 359, 396, 3329, 3343, 3476], 'RON': [80, 93, 108, 123, 135, 155, 159, 165, 288, 301, 316, 331, 343, 363, 367, 373, 459, 462, 1300, 1421, 1442, 1468, 1487, 1513, 1531, 1549, 1561, 1571, 2010, 2039, 2044, 2197, 2204, 2228, 2252, 2301, 2344, 2380, 2402, 2416, 2445, 2468, 2495, 2514, 2522, 2536, 2548, 2677, 2719, 2736, 2744, 2770, 2779, 2790, 2872, 2894, 2905, 2917, 2942, 2961, 2968, 2977, 2984, 2990, 3008, 3038, 3046, 3119, 3130, 3159, 3168, 3181, 3216, 3232, 3277, 3477, 3707, 3726, 3775, 3813, 3840, 3848, 3904], 'itself': [81, 289, 2969, 3332], 'c-Src.': [83, 291, 2797, 3044, 3334], 'This': [84, 194, 292, 402, 2154, 2885, 3056, 3803], 'conclusion': [85, 293], 'is': [86, 294, 558, 1205, 1302, 1535, 2011, 2111, 2122, 2169, 2266, 2446, 2957, 3033, 3039, 3049, 3109, 3131, 3422, 3492, 3695, 3720, 3732, 3779, 3822, 4002], 'based': [87, 295], 'these': [89, 138, 297, 346, 1491, 2422, 2652, 3768, 3855], 'observations:': [90, 298], '1)': [91, 299, 2007], 'ECM-induced': [92, 147, 300, 355, 1512, 2033, 2251, 2401, 2941, 2960, 3112, 3118, 3153, 3231, 3260, 3346, 3384], 'was': [95, 303, 1267, 1960, 2230, 2345, 2353, 2424, 2496, 2720, 2738, 2762, 2772, 2924, 2980, 3565, 3611, 3814], 'inhibited': [96, 304], 'expressing': [99, 127, 307, 335, 1547, 2219, 3295, 3522], 'kinase-inactive': [100, 308, 2412, 2481, 2936, 3244, 3265, 3363], 'c-Src;': [101, 309], '2)': [102, 310], 'active': [103, 132, 311, 340, 2463, 2733, 2755, 3014, 3274], 'c-Src': [104, 133, 152, 191, 312, 341, 360, 399, 2128, 2159, 2161, 2168, 2296, 2324, 2399, 2413, 2456, 2465, 2482, 2493, 2511, 2533, 2545, 2564, 2698, 2734, 2756, 2898, 2937, 2956, 3016, 3191, 3245, 3266, 3275, 3357, 3364, 3404, 3413, 3434, 3516, 3576, 3596, 3704], 'could': [105, 131, 313, 339, 2036, 3794, 3804], 'phosphorylate': [106, 134, 314, 342, 2065, 2458, 2521, 2535, 2566, 3021, 3406, 3706], 'immunoprecipitated': [107, 136, 315, 344, 2346, 2469, 2497, 2721, 2743, 3023, 3612], 'from': [109, 114, 137, 317, 322, 345, 1962, 2347, 2470, 2498, 2515, 2523, 2549, 2670, 2678, 2683, 2722, 2953, 3024, 3278, 3283, 3615, 3708, 3734], 'ECM-stimulated': [110, 318, 2679], 'but': [112, 320, 2518, 2537, 2681, 3281, 3371, 3713], 'not': [113, 121, 321, 329, 1504, 1516, 1563, 2004, 2682, 2870, 3006, 3011, 3020, 3030, 3040, 3282, 3714], 'unstimulated': [115, 323, 2503, 2524, 2684, 3235, 3284], 'cells;': [116, 324, 2838], '3)': [118, 326, 1448], 'did': [120, 328, 3005, 3019], 'cause': [122, 330, 3007], 'kinase-dead': [128, 336, 458, 2989], 'nor': [130, 338], 'cells.': [139, 347, 2216, 2473, 2687, 2996], 'data': [141, 349, 1085, 2435, 3317, 3661], 'fit': [142, 350], 'a': [143, 167, 199, 351, 375, 407, 1270, 1437, 1464, 1497, 1963, 1983, 1989, 2170, 2259, 2267, 2396, 2410, 2729, 2784, 2873, 2895, 2918, 2950, 2988, 3041, 3188, 3493, 3668, 3696], 'integrin': [148, 356, 1088, 2015, 2034, 2104, 3135, 3154], 'aggregation': [149, 357, 972, 2035, 2105, 3155], 'causes': [150, 358, 3164], 'activation': [153, 361, 1198, 1401, 1514, 1534, 2107, 2121, 3122], 'oligomerization': [156, 364, 3160], 'followed': [157, 365], 'kinase-dependent': [160, 368], 'autophosphorylation;': [161, 369], 'this': [162, 370, 1187, 1427, 3491, 3693, 3883], 'results': [163, 371, 1540, 2530, 2654, 3115, 3198, 3787, 3896], 'becoming': [166, 374], 'target': [168, 376, 2874, 2896, 2919, 3189], 'activated': [170, 378, 2061, 2080, 2449, 3192], 'c-Src,': [171, 379, 2077, 2258, 2878, 3432], 'phosphorylates': [173, 381, 2676], 'additional': [174, 382, 3034, 3203, 3257, 3407, 3427], 'tyrosines': [175, 383, 3204, 3408, 3428, 3742, 3769, 3901], 'RON.': [177, 385, 3055, 3206, 3748], 'Integrin-induced': [178, 386, 1023], 'epidermal': [179, 387, 423, 1024], '(EGFR)': [183, 391], 'also': [185, 393, 1093, 2477, 2863, 3286, 3780], 'EGFR': [189, 397, 3297, 3300, 3324, 3331, 3337, 3347, 3385, 3396, 3421, 3430, 3438, 3524, 3559, 3579, 3610, 3648, 3671], 'activities.': [193, 401, 3519], 'sequence': [195, 403], 'appears': [196, 404, 3382], 'general': [200, 408], 'integrin-dependent': [203, 411, 1346, 1414], 'activation.': [207, 415], 'dominant-negative': [418], "Dulbecco's": [419], 'modified': [420], "Eagle's": [421], 'medium': [422, 3549, 3831], 'EGF': [426, 1633, 3079, 3532, 3546, 3679], 'focal': [428, 2072], 'fetal': [431], 'calf': [432], 'serum': [433, 1271], 'myelin': [434], 'basic': [435], 'protein': [436, 442, 1215], 'Madin-Darby': [437], 'canine': [438], 'kidney': [439], '3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium': [443], 'bromide': [444], 'platelet-derived': [445, 1029], 'polyacrylamide': [452], 'gel': [453], 'electrophoresis': [454], '"recepteur': [455], "d'origine": [456], 'Nantais"': [457], 'wild': [460, 2202], 'type': [461, 1875, 2203], 'Growth,': [463, 3907], 'survival': [466, 730, 3910, 4174], 'anchorage-dependent': [468, 3912], 'are': [470, 1345, 1975, 2003, 2655, 2799, 2809, 3187, 3212, 3253, 3401, 3659, 3740, 3914], 'through': [472, 3916], 'signals': [473, 3917], 'generated': [474, 3918], 'ECM1and': [478, 3922], 'soluble': [480, 3924], 'factors': [482, 3926], '(1.Porter': [483, 3927], 'J.C.': [484, 3928], 'Hogg': [485, 3929], 'N.': [486, 3930], 'Trends': [487, 3931], 'Cell': [488, 517, 533, 609, 628, 664, 696, 783, 855, 874, 1048, 1284, 1328, 1364, 1380, 1639, 1658, 1718, 1750, 1769, 1807, 1937, 2023, 2099, 3068, 3143, 3932, 3961, 3977, 4053, 4072, 4108, 4140, 4227], 'Biol.': [489, 518, 534, 610, 629, 715, 784, 856, 875, 958, 1049, 1131, 1640, 1659, 1719, 1751, 1770, 1808, 2145, 2278, 2586, 2637, 3069, 3870, 3933, 3962, 3978, 4054, 4073, 4159, 4228], '1998;': [490, 698, 749, 901, 1015, 1076, 1686, 3098, 3934, 4142, 4193], '8:': [491, 3935], '390-396Abstract': [492, 3936], 'Full': [493, 495, 579, 720, 722, 1136, 1138, 2591, 2593, 2642, 2644, 3937, 3939, 4023, 4164, 4166], 'Text': [494, 496, 580, 721, 723, 1137, 1139, 2592, 2594, 2643, 2645, 3938, 3940, 4024, 4165, 4167], 'PDF': [497, 581, 724, 1140, 2595, 2646, 3941, 4025, 4168], 'PubMed': [498, 509, 522, 538, 551, 582, 614, 633, 654, 669, 701, 725, 752, 771, 788, 804, 826, 860, 879, 904, 920, 942, 963, 986, 1018, 1053, 1079, 1119, 1141, 1177, 1235, 1261, 1289, 1333, 1369, 1385, 1628, 1644, 1663, 1689, 1706, 1723, 1739, 1755, 1774, 1790, 1812, 1835, 1853, 2028, 2054, 2094, 2149, 2185, 2282, 2596, 2619, 2647, 3073, 3101, 3148, 3457, 3874, 3942, 3953, 3966, 3982, 3995, 4026, 4058, 4077, 4098, 4113, 4145, 4169, 4196, 4215, 4232, 4248, 4270], 'Scopus': [499, 510, 523, 539, 552, 583, 615, 634, 655, 726, 753, 772, 789, 805, 827, 861, 880, 905, 921, 943, 964, 987, 1019, 1054, 1080, 1120, 1142, 1178, 1236, 1262, 1290, 1334, 1370, 1386, 1629, 1645, 1664, 1690, 1707, 1724, 1740, 1756, 1775, 1791, 1813, 1836, 1854, 2029, 2055, 2095, 2150, 2186, 2283, 2597, 2620, 2648, 3074, 3102, 3149, 3458, 3875, 3943, 3954, 3967, 3983, 3996, 4027, 4059, 4078, 4099, 4170, 4197, 4216, 4233, 4249, 4271], '(209)': [500, 3944], 'Google': [501, 512, 525, 541, 554, 585, 617, 636, 657, 670, 702, 728, 755, 774, 791, 807, 829, 863, 882, 907, 923, 945, 966, 989, 1021, 1056, 1082, 1122, 1144, 1180, 1238, 1264, 1292, 1336, 1372, 1388, 1631, 1647, 1666, 1692, 1709, 1726, 1742, 1758, 1777, 1793, 1815, 1838, 1856, 2031, 2057, 2097, 2152, 2188, 2285, 2599, 2622, 2650, 3076, 3104, 3151, 3460, 3877, 3945, 3956, 3969, 3985, 3998, 4029, 4061, 4080, 4101, 4114, 4146, 4172, 4199, 4218, 4235, 4251, 4273], 'Scholar,': [502, 513, 526, 542, 618, 658, 703, 775, 792, 808, 864, 908, 924, 946, 1057, 1123, 1239, 1648, 1667, 1693, 1710, 1727, 1759, 1778, 2600, 2623, 3946, 3957, 3970, 3986, 4062, 4102, 4147, 4219, 4236, 4252], '2.Juliano': [503, 3947], 'R.': [504, 810, 926, 1103, 1161, 1230, 1613, 1615, 1819, 2049, 3948, 4254], 'BioEssays.': [505, 2050, 2090, 2181, 3949], '1996;': [506, 611, 630, 857, 876, 1050, 1330, 1366, 1625, 1641, 1660, 1752, 1771, 1809, 2051, 2588, 3070, 3950, 4055, 4074], '18:': [507, 824, 940, 1117, 1175, 1833, 2052, 3951, 4268], '911-917Crossref': [508, 2053, 3952], '(114)': [511, 2056, 3955], '3.Schwartz': [514, 3958], 'M.A.': [515, 528, 648, 3959, 3972, 4092], 'J.': [516, 608, 627, 650, 663, 695, 705, 714, 748, 765, 779, 782, 800, 822, 854, 873, 900, 916, 938, 1014, 1047, 1075, 1115, 1130, 1173, 1257, 1638, 1657, 1685, 1700, 1714, 1717, 1735, 1749, 1768, 1786, 1806, 1831, 1849, 2585, 2636, 3067, 3097, 3960, 4052, 4071, 4094, 4107, 4139, 4149, 4158, 4192, 4209, 4223, 4226, 4244, 4266], '1997;': [519, 651, 785, 801, 917, 1720, 1736, 1787, 1850, 2091, 2182, 3963, 4095, 4229, 4245], '139:': [520, 786, 1721, 3964, 4230], '575-578Crossref': [521, 3965], '(303)': [524, 3968], '4.Schwartz': [527, 3971], 'Baron': [529, 3973], 'V.': [530, 3974], 'Curr.': [531, 3975], 'Opin.': [532, 3976], '1999;': [535, 548, 666, 717, 823, 939, 983, 1116, 1133, 1174, 1382, 1832, 2025, 2616, 2639, 3145, 3454, 3979, 3992, 4110, 4161, 4267], '11:': [536, 3980], '197-202Crossref': [537, 3981], '(217)': [540, 3984], '5.Giancotti': [543, 3987], 'F.G.': [544, 979, 3988], 'Ruoslahti': [545, 797, 913, 980, 1732, 1783, 1846, 3989, 4241], 'E.': [546, 798, 914, 981, 1127, 1733, 1784, 1847, 3990, 4242], 'Science.': [547, 982, 1231, 3991], '285:': [549, 984, 3993], '1028-1032Crossref': [550, 985, 3994], '(3787)': [553, 988, 3997], 'Scholar).': [555, 586, 671, 967, 1022, 1083, 1181, 1265, 1293, 1389, 2098, 2153, 3461, 3878, 3999, 4030, 4115, 4274], 'Cell-matrix': [556, 4000], 'interaction': [557, 2155, 4001], 'mediated': [559, 1536, 3423, 4003], 'integrins,': [561, 4005], 'transmembrane': [562, 4006], 'noncovalently': [563, 4007], 'linked': [564, 4008], 'heterodimeric': [565, 4009], 'consisting': [567, 4011], 'α': [569, 4013], 'β': [571, 2114, 4015], 'subunits': [572, 4016], '(6.Hynes': [573, 4017], 'R.O.': [574, 4018], 'Cell.': [575, 959, 2144, 2277, 3869, 4019], '1992;': [576, 4020], '69:': [577, 4021], '11-25Abstract': [578, 4022], '(8966)': [584, 4028], 'Integrin': [587, 4031], 'engagement': [588, 4032], 'modulate': [592, 4036], 'signaling': [595, 4039], 'pathways,': [596, 4040], 'increasing': [597, 4041], 'RTKs': [603, 996, 1091, 4047], '(7.Sundberg': [604, 850, 1043, 1634, 1745, 3063, 4048], 'C.': [605, 736, 851, 888, 1002, 1044, 1063, 1220, 1247, 1635, 1673, 1746, 3064, 3085, 4049, 4180], 'Rubin': [606, 852, 1045, 1636, 1747, 3065, 4050], 'K.': [607, 796, 853, 912, 954, 1046, 1637, 1731, 1748, 1782, 1845, 3066, 4051, 4240], '132:': [612, 858, 1051, 1642, 1753, 3071, 4056], '741-752Crossref': [613, 859, 1052, 1643, 1754, 3072, 4057], '(178)': [616, 862, 1055, 1646, 1757, 3075, 4060], '8.Miyamoto': [619, 865, 1649, 1760, 4063], 'S.': [620, 812, 866, 928, 1105, 1163, 1623, 1650, 1761, 1799, 1821, 2614, 3452, 4064, 4256], 'Teramoto': [621, 867, 1651, 1762, 1800, 4065], 'H.': [622, 868, 1652, 1763, 1801, 4066], 'Gutkind': [623, 869, 1653, 1764, 1802, 4067], 'J.S.': [624, 870, 1654, 1765, 1803, 2604, 2625, 3442, 4068], 'Yamada': [625, 871, 1655, 1766, 1804, 4069], 'K.M.': [626, 872, 1656, 1767, 1805, 4070], '135:': [631, 877, 1661, 1772, 1810, 4075], '1633-1642Crossref': [632, 878, 1662, 1773, 1811, 4076], '(675)': [635, 881, 1665, 1776, 1814, 4079], 'Scholar)': [637, 990, 1145, 1337, 1857, 2058, 3077, 3105, 4081], 'their': [639, 835, 4083, 4280], 'downstream': [640, 1605, 2260, 3801, 4084], 'intracellular': [641, 4085], 'mediators': [642, 1606, 4086], '(9.Renshaw': [643, 4087], 'M.W.': [644, 4088], 'Ren': [645, 4089], 'X.D.': [646, 4090], 'Schwartz': [647, 4091], 'EMBO': [649, 747, 799, 821, 899, 915, 937, 1013, 1074, 1114, 1172, 1256, 1684, 1734, 1785, 1830, 1848, 3096, 4093, 4191, 4243, 4265], '16:': [652, 802, 918, 1737, 1788, 1851, 4096, 4246], '5592-5599Crossref': [653, 4097], '(269)': [656, 4100], '10.Aplin': [659, 4103], 'A.E.': [660, 4104], 'Juliano': [661, 4105], 'R.L.': [662, 4106], 'Sci.': [665, 697, 1621, 2612, 3450, 4109, 4141], '112:': [667, 4111], '695-706Crossref': [668, 4112], 'Integrin-based': [672, 4116], 'effects': [673, 1212, 1341, 3053, 4117], 'include': [678, 4122], 'enhancement': [679, 4123], 'migration': [682, 4126], '(11.Woodard': [683, 4127], 'A.S.': [684, 4128], 'Garcia-Cardena': [685, 4129], 'G.': [686, 744, 818, 896, 934, 1010, 1071, 1111, 1169, 1241, 1681, 1827, 2576, 3093, 4130, 4188, 4262], 'Leong': [687, 4131], 'M.': [688, 734, 781, 794, 814, 886, 910, 930, 1000, 1061, 1107, 1165, 1249, 1671, 1716, 1729, 1780, 1823, 1843, 3083, 4132, 4178, 4225, 4238, 4258], 'Madri': [689, 4133], 'J.A.': [690, 2142, 2275, 2582, 4134], 'Sessa': [691, 4135], 'W.C.': [692, 4136], 'Languino': [693, 4137], 'L.R.': [694, 4138], '111:': [699, 4143], '469-478Crossref': [700, 4144], '12.Li': [704, 4148], 'Lin': [706, 4150], 'M.L.': [707, 4151], 'Wiepz': [708, 4152], 'G.J.': [709, 4153], 'Guadarrama': [710, 4154], 'A.G.': [711, 4155], 'Bertics': [712, 4156], 'P.J.': [713, 1253, 4157], 'Chem.': [716, 1132, 2587, 2638, 4160], '274:': [718, 1134, 2640, 4162], '11209-11219Abstract': [719, 4163], '(70)': [727, 4171], 'Scholar),': [729, 756, 1632, 1743, 1794, 1816, 1839, 2032, 3152, 4173, 4200], '(13.Moro': [731, 997, 3080, 4175], 'L.': [732, 738, 742, 884, 890, 894, 998, 1004, 1008, 1059, 1065, 1069, 1224, 1245, 1669, 1675, 1679, 3081, 3087, 3091, 4176, 4182, 4186], 'Venturino': [733, 885, 999, 1060, 1670, 3082, 4177], 'Bozzo': [735, 887, 1001, 1062, 1672, 3084, 4179], 'Silengo': [737, 889, 1003, 1064, 1674, 3086, 4181], 'Altruda': [739, 891, 1005, 1066, 1676, 3088, 4183], 'F.': [740, 820, 892, 936, 1006, 1067, 1113, 1171, 1677, 1829, 3089, 4184, 4264], 'Beguinot': [741, 893, 1007, 1068, 1678, 3090, 4185], 'Tarone': [743, 817, 895, 933, 1009, 1070, 1110, 1168, 1680, 1826, 3092, 4187, 4261], 'Defilippi': [745, 815, 897, 931, 1011, 1072, 1108, 1166, 1682, 1824, 3094, 4189, 4259], 'P.': [746, 816, 898, 932, 1012, 1073, 1109, 1167, 1683, 1825, 3095, 4190, 4260], '17:': [750, 902, 1016, 1077, 1687, 3099, 4194], '6622-6632Crossref': [751, 903, 1017, 1078, 1688, 3100, 4195], '(503)': [754, 906, 1020, 1081, 1691, 3103, 4198], 'proliferation': [758, 4202], '(14.Cybulsky': [759, 4203], 'A.V.': [760, 1695, 4204], 'McTavish': [761, 1696, 4205], 'A.J.': [762, 1697, 4206], 'Cyr': [763, 1698, 4207], 'M.D.': [764, 1699, 4208], 'Clin.': [766, 1701, 4210], 'Invest.': [767, 1702, 4211], '1994;': [768, 1232, 1258, 1703, 4212], '94:': [769, 1704, 4213], '68-78Crossref': [770, 1705, 4214], '(58)': [773, 1708, 4217], '15.Jones': [776, 1711, 4220], 'P.L.': [777, 1712, 4221], 'Crack': [778, 1713, 4222], 'Rabinovitch': [780, 1715, 4224], '279-293Crossref': [787, 1722, 4231], '(304)': [790, 1725, 4234], '16.Schneller': [793, 909, 1728, 1779, 4237], 'Vuori': [795, 911, 1730, 1781, 1844, 4239], '5600-5607Crossref': [803, 919, 1738, 1789, 1852, 4247], '(424)': [806, 922, 1741, 1792, 1855, 4250], '17.Soldi': [809, 925, 4253], 'Mitola': [811, 927, 1104, 1162, 1820, 4255], 'Strasly': [813, 929, 1106, 1164, 1822, 4257], 'Bussolino': [819, 935, 1112, 1170, 1828, 4263], '882-892Crossref': [825, 941, 1118, 1176, 1834, 4269], '(525)': [828, 944, 1121, 1179, 1837, 4272], 'Scholar).As': [830], 'basis': [833, 4278], 'collaboration,': [836, 4281], 'may': [842, 3498, 3770, 4287], 'form': [843, 4288], 'macromolecular': [844], 'complexes': [845], 'membrane': [849, 3637], 'Scholar,13.Moro': [883], '18.Plopper': [947], 'G.E.': [948], 'McNamee': [949], 'H.P.': [950], 'Dikem': [951], 'L.E.': [952], 'Bojanowski': [953], 'Inberg': [955], 'D.E.': [956], 'Mol.': [957, 2143, 2276, 3868], '1995;': [960, 2146, 2279], '6:': [961], '1349-1365Crossref': [962], '(469)': [965], 'In': [968, 1390, 1565, 1986, 2217, 2554, 3313, 3352], 'that': [969, 1087, 1208, 1273, 1298, 1339, 1519, 1558, 1864, 2233, 2245, 2444, 2500, 2532, 2538, 2563, 2865, 2929, 2949, 2967, 2972, 3036, 3061, 3117, 3175, 3288, 3383, 3464, 3490, 3496, 3703, 3722, 3735, 3760, 3782, 3825], 'case,': [970], 'adhesion-induced': [971], 'might': [975, 1092, 2064, 2664, 2899, 2970], 'trigger': [976], 'co-aggregation': [977], '(5.Giancotti': [978], 'autophosphorylation': [992, 2208, 2289, 3400], '(EGF)': [1027], '(PDGF)': [1032], 'depends': [1035, 3511], '13.Moro': [1058, 1668], 'Recent': [1084, 1294], 'suggest': [1086, 3116], 'association': [1089], 'with': [1090, 1496, 1543, 1551, 1598, 1921, 1927, 2013, 2113, 2205, 2237, 2312, 2320, 2328, 2358, 2372, 2409, 2427, 2438, 2479, 2506, 2552, 2656, 2694, 2701, 2745, 2822, 2848, 3001, 3059, 3133, 3209, 3228, 3239, 3250, 3264, 3315, 3436, 3529, 3585, 3594, 3629, 3638, 3772], 'protect': [1094], 'latter': [1096], 'against': [1097], 'phosphatases': [1101], '(17.Soldi': [1102, 1160, 1818], '19.DeMali': [1124], 'K.A.': [1125, 1251], 'Balciunaite': [1126], 'Kazlauskas': [1128], 'A.': [1129, 1226, 1243, 1282, 1314, 1320, 1350, 1356, 1374, 1376, 1624, 2017, 2019, 2615, 3137, 3139, 3453, 3861, 3865], '19551-19558Abstract': [1135], '(74)': [1143], 'and/or': [1146], 'ensure': [1147], 'correct': [1149], 'subcellular': [1150], 'juxtaposition': [1151], 'cytoplasmic': [1153, 2070, 3745, 3905], 'tails': [1154], 'dimerized': [1156], 'Despite': [1182], 'cited': [1184], 'progress': [1185], 'area': [1188], 'research,': [1190], 'molecular': [1192, 1424, 1990], 'mechanisms': [1193, 1425], 'underlying': [1194], 'remain': [1201], 'defined.RON': [1204], 'mediates': [1209], 'biological': [1211], '(MSP)': [1216], '(20.Wang': [1217], 'M.-H.': [1218, 1312, 1348], 'Ronsin': [1219], 'Gesnel': [1221], 'M.-C.': [1222], 'Coupey': [1223], 'Skeel': [1225, 1281, 1319, 1355, 1375, 2018, 3138, 3864], 'Leonard': [1227, 1325, 1361, 1377, 2020, 3140, 3866], 'E.J.': [1228, 1280, 1326, 1362, 1378, 2021, 3141, 3867], 'Breathnach': [1229], '266:': [1233], '117-119Crossref': [1234], '(247)': [1237], '21.Gaudino': [1240], 'Follenzi': [1242], 'Naldini': [1244], 'Collesi': [1246], 'Santoro': [1248], 'Gallo': [1250], 'Godowski': [1252], 'Comoglio': [1254], 'P.M.': [1255], '13:': [1259], '3524-3532Crossref': [1260], '(291)': [1263], 'MSP': [1266, 1459, 1475, 1579, 1932, 2507, 2827, 2851, 2867, 2889, 3002, 3716, 3785, 3853, 3895], 'discovered': [1268], 'as': [1269, 2009, 2334, 2709, 2728, 2783, 3303, 3305, 3667], 'regulates': [1274], 'motility': [1276], 'macrophages': [1278], '(22.Leonard': [1279], 'Exp.': [1283, 1327, 1363, 1379, 2022, 3142], 'Res.': [1285, 1329, 1365, 1381, 2024, 3144], '1976;': [1286], '102:': [1287], '434-438Crossref': [1288], '(94)': [1291], 'investigations': [1295], 'have': [1296, 1607], 'shown': [1297, 1976, 2810], 'expressed': [1303, 2782, 2987, 3666], 'various': [1305, 1860], 'types': [1307, 1525], 'including': [1308], '(23.Wang': [1311, 1347], 'Iwama': [1313, 1349], 'Dlugosz': [1315, 1351], 'A.A.': [1316, 1352], 'Sun': [1317, 1353], 'Y.': [1318, 1354], 'Yuspa': [1321, 1357], 'S.H.': [1322, 1358], 'Suda': [1323, 1359], 'T.': [1324, 1360, 2578], '226:': [1331, 1367], '39-46Crossref': [1332, 1368], '(99)': [1335, 1371], 'MSP-mediated': [1340], 'Scholar,24.Danilkovitch': [1373], '248:': [1383, 2026, 3146], '575-582Crossref': [1384, 2027, 3147], '(30)': [1387, 2030, 3150], 'present': [1392, 1407], 'work,': [1393, 1408], 'we': [1394, 1409, 1998, 2199, 2404, 2986], 'RON.RESULTS': [1403], 'AND': [1404], 'DISCUSSIONIn': [1405], 'effect': [1412, 1521, 1569, 1995, 3222, 3225, 3367, 3577], 'functional': [1418], 'mediating': [1426, 1992], 'effect.': [1428], 'Plating': [1429], 'HEK': [1432, 2214, 2305, 2406, 2471, 2689, 2994], '293': [1433, 2215, 2306, 2308, 2407, 2472, 2690, 2995], 'collagen-coated': [1438, 3833], 'substrate': [1439, 2730, 3042], 'induced': [1440, 1489, 3467, 3674, 3729, 3736], 'ligand-independent': [1441, 3299], '(Fig.1': [1445, 2908], 'A,': [1446, 2688], 'lane': [1447, 1454], '(Fig.': [1452, 1479, 2240, 2418, 3246, 3267, 3310, 3349, 3377, 3717], '1B,': [1453], '3).': [1455, 3247], 'Addition': [1457], 'collagen-adherent': [1461], 'higher': [1465], 'level': [1466, 2225, 3174], 'than': [1473], 'either': [1474, 2502, 2932], 'or': [1476, 1508, 1597, 1604, 1919, 1928, 2294, 2319, 2332, 2504, 2508, 2525, 2568, 2672, 2685, 2707, 2750, 2824, 2836, 2935, 3003, 3026, 3533, 3547, 3593, 3784, 3818], 'collagen': [1477, 1874, 1923, 2299, 2330, 2703, 2823, 2825, 2849, 2891, 3004, 3537, 3681], 'alone': [1478, 1596, 2239, 2747, 2868, 3550], '1,A': [1480], 'B).': [1482, 3379], 'time': [1484], 'courses': [1485], 'different': [1492, 3483, 3791, 3807, 3900], 'stimuli': [1493], 'were': [1494, 1541, 1911, 1939, 2326, 2436, 2476, 2501, 2699, 3525, 3583, 3606], 'comparable,': [1495], 'plateau': [1498], 'at': [1499, 3567, 3653], 'about': [1500, 1988, 2231], '30': [1501, 3554], 'min': [1502], '(data': [1503, 1515, 1562, 3010, 3029], 'shown).': [1505, 1564, 3012], 'RGD-containing': [1506], 'peptide': [1507], 'anti-β1-integrin': [1509], 'antibodies': [1510, 2360, 2374, 3640], 'blocked': [1511, 3242, 3342], 'shown),': [1517, 3031], 'indicating': [1518, 1863], '(collagen': [1524], 'I': [1526], 'IV,': [1528, 1924, 2331], 'fibronectin)': [1529], 'integrins.': [1538], 'Similar': [1539], 'obtained': [1542], 'MDCK': [1544, 3520, 3581], 'stably': [1546], 'transfected': [1548, 2236, 2405, 2478, 3604], 'human': [1553], 'HaCat': [1554], 'keratinocyte': [1555], 'line': [1557], 'expresses': [1559], 'endogenous': [1560, 3296, 3523], 'addition': [1566, 2485], 'activity,': [1575, 3560], 'combination': [1577, 3677], 'maximized': [1582], 'numbers,': [1585], 'measured': [1586, 1940], 'after': [1587, 2126, 3601], '48': [1588, 1941], 'h': [1589, 1942, 1954], 'culture': [1591, 1948], '(TableI).': [1592], 'Effects': [1593], 'ECM,': [1595, 3712], 'factor,': [1600], 'been': [1608, 2561], 'described': [1609, 2335, 2710], 'Met': [1611], '(25.Wang': [1612], 'Kobayashi': [1614], 'Bishop': [1616], 'J.M.': [1617], 'Proc.': [1618, 2609, 3447], 'Natl.': [1619, 2610, 3448], 'Acad.': [1620, 2611, 3449], 'U.': [1622, 2613, 3451], '93:': [1626], '8425-8430Crossref': [1627], '(116)': [1630], '14.Cybulsky': [1694], 'PDGF': [1744, 3062], 'fibroblast': [1795], '(8.Miyamoto': [1798], 'VEGFR-2': [1817], 'insulin': [1841], '(16.Schneller': [1842], 'types,': [1862], 'cell-ECM': [1865, 2084], 'interactions': [1866], 'frequently': [1867], 'regulate': [1868], 'factor-RTK': [1870], 'responses.Table': [1871], 'IEffect': [1872], 'IV': [1876, 2704, 3538], 'MSP-induced': [1878], 'accumulation': [1879], 'RE7': [1881], '(MDCK': [1882], 'RON-expressing)': [1883], 'cellsCell': [1884], 'no.': [1885], '×': [1886], '10−4Uncoated': [1887], 'wells1.5': [1888], '±': [1889, 1896, 1900, 1908, 1969, 2801], '0.2Uncoated': [1890], 'wells': [1891, 1903, 1949], '+': [1892, 1904, 2829, 2850], '1': [1893, 1905, 1930, 3186, 3211], 'nm': [1894, 1906, 1931, 3562], 'MSP3.2': [1895], '0.3Collagen': [1897], 'IV-coated': [1898, 1902], 'wells3.8': [1899], '0.4Collagen': [1901], 'MSP5.6': [1907], '0.5Cells': [1909], '(104/well)': [1910], 'distributed': [1912], 'triplicate': [1914], '96-well': [1916], 'plates,': [1917], 'uncoated': [1918], 'coated': [1920], 'mouse': [1922, 3536], 'incubated': [1926], 'without': [1929, 1935], 'DMEM': [1934], 'FCS.': [1936], 'numbers': [1938, 3652], 'later': [1943], 'adding': [1945, 2462], 'MTT': [1946], 'measuringA': [1951], '570': [1952], '2': [1953, 2241, 2419, 2945, 3241, 3252], 'later.': [1955], 'number': [1957], 'determined': [1961, 2354, 2452, 2739], 'standard': [1964], 'calibration': [1965], 'curve.': [1966], 'means': [1968, 2800], 'S.E.': [1970, 2802], 'three': [1972], 'independent': [1973, 2805], 'experiments': [1974], 'table.': [1979], 'Open': [1980], 'table': [1981], 'new': [1984], 'tab': [1985], 'thinking': [1987], 'mechanism': [1991], 'considered': [1999, 2964], 'two': [2000, 3125], 'possibilities,': [2001], 'mutually': [2005], 'exclusive.': [2006], 'Inasmuch': [2008], 'associated': [2012, 2112, 3132], 'β1': [2014, 3134], '(24.Danilkovitch': [2016, 3136], 'result': [2037, 2902, 3805], 'oligomerization,': [2040], 'transphosphorylation,': [2041, 3162], 'increased': [2043, 2904, 3306], 'activity;': [2046], '(2.Juliano': [2048], 'activate': [2067], 'RON.Two': [2068], 'tyrosine-specific': [2069], 'kinases,': [2071], '(FAK)': [2075], 'response': [2082, 2882], '(26.Hanks': [2086, 2177], 'S.K.': [2087, 2178], 'Polte': [2088, 2179], 'T.R.': [2089, 2180], '19:': [2092, 2183], '137Crossref': [2093, 2184], '(440)': [2096, 2187], 'induces': [2103], 'FAK,': [2109], 'integrin.': [2115], 'initial': [2117], 'step': [2118, 3185, 3210, 3240, 3251, 3881], 'FAK': [2120, 2157, 2166, 2194, 2211, 2222, 2247, 2315, 2430, 2934, 2954], 'transphosphorylation': [2123], 'Tyr397,': [2125], 'bind': [2130], 'phosphorylated': [2131, 2447, 2778, 3183, 3437, 3663], 'Tyr397': [2132, 2265], 'via': [2133, 3193, 3388, 3472], 'its': [2134], 'SH2': [2135], 'domain': [2136, 3746], '(27.Eide': [2137, 2270], 'B.L.': [2138, 2271], 'Turck': [2139, 2272], 'C.W.': [2140, 2273, 2580], 'Escobedo': [2141, 2274], '15:': [2147, 2280], '2819-2827Crossref': [2148, 2281], '(162)': [2151, 2284], 'increases': [2160, 3762], 'activity.': [2163, 2494, 3777], 'Activation': [2164], 'key': [2171], 'point': [2172], 'signal': [2175], 'transduction': [2176], 'Scholar).To': [2189], 'study': [2190], 'phosphorylation,': [2198, 2403, 2985, 3370, 3580], 'co-expressed': [2200], 'transiently': [2201, 2310, 2692], 'major': [2207, 2288], 'site': [2209, 2269, 2290], '(Y397F)': [2210], 'mutant': [2212, 2249, 2292, 2317, 2431], 'Y397F': [2221, 2248, 2291, 2316, 2429, 2933], 'mutant,': [2223], 'collagen-induced': [2227], 'one-half': [2232], 'vector': [2238, 3587, 3592], 'A).': [2242, 2433, 3312, 3351], 'fact': [2244, 2928, 3463, 3702, 3824], 'decreased': [2250, 2940], 'suggested': [2254], 'involvement': [2256], 'kinase,': [2261], 'FAK-phosphorylated': [2264], 'binding': [2268], 'Scholar).Figure': [2286], '2FAK': [2287], '(A)': [2293, 2318, 3514], 'dn': [2295, 2323, 2411, 2697, 3595], '(B)': [2297, 2325, 3517], 'inhibits': [2298], 'IV-induced': [2300], 'cells.HEK': [2307], 'co-transfected': [2311, 2693, 3584], 'RONwt': [2313, 2321, 2695], 'plus': [2314, 2322, 2826], 'stimulated': [2327, 2505, 2551, 2700, 2821, 2847, 3526, 3710, 3815], 'MSP,': [2329, 2702], 'both,': [2333, 2708], 'legend': [2338, 2713], 'Fig.': [2340, 2715, 3755], '1.': [2341, 2716], 'After': [2342, 2717, 3608], 'stimulation,': [2343, 2718, 3609], 'lysates,': [2349], 'Western': [2356, 3627], 'blotting': [2357, 3628], 'anti-PY': [2359, 3630], '(WB:': [2361, 3631], 'PY)': [2362, 3632], '(A': [2363], 'andB,': [2364, 3758], 'upper': [2365], 'panels).': [2366], 'lower': [2368], 'panels': [2369], 'represent': [2370], 're-blotting': [2371], 'anti-RON': [2373], 'estimate': [2376, 3643], 'amount': [2378, 3646], 'precipitates.': [2382, 3650], 'MOCK:': [2383], 'empty': [2384, 3586], 'vector.View': [2385], 'Large': [2386, 2854, 3683], 'Image': [2387, 2855, 3684], 'Figure': [2388, 2856, 3685], 'ViewerDownload': [2389, 2857, 3686], 'Hi-res': [2390, 2858, 3687], 'image': [2391, 2859, 3688], 'Download': [2392, 2860, 3689], '(PPT)To': [2393], 'test': [2394, 2975], 'construct.': [2414], 'Collagen-induced': [2415], 'B)': [2420], 'reduced': [2425], 'comparable': [2426], '(Fig.2': [2432], 'These': [2434, 2474, 2529], 'consistent': [2437, 3208, 3249], 'postulated': [2440], 'ECM-integrin-FAK-c-Src': [2441], 'pathway,': [2442, 3196], 'suggesting': [2443, 2948], 'c-Src.We': [2450], 'therefore': [2451, 3886], 'capacity': [2454, 3419], 'RONin': [2459], 'vitro': [2460, 2727, 3018, 3272], 'purified': [2464, 2732, 3015], 'enzyme': [2466], 'construct,': [2483], 'prevent': [2489], 'possible': [2490, 3781], 'vivo': [2492], 'collagen.': [2509, 2884], 'Active': [2510], 'vitrophosphorylated': [2513], 'collagen-stimulated': [2516], 'failed': [2519], 'MSP-stimulated': [2526, 2686, 2837, 3027], '(Fig.3).': [2528], 'indicate': [2531], 'sites': [2539, 3798], 'become': [2540, 3835], 'available': [2541], 'only': [2546, 2938], 'ECM.': [2553], 'contrast': [2555], 'our': [2557, 3316], 'findings,': [2558], 'it': [2559, 2879, 3372, 3381], 'has': [2560], 'reported': [2562], 'nonstimulated': [2567, 2833], 'ligand-stimulated': [2569], '(28.Peterson': [2573], 'J.E.': [2574], 'Kulik': [2575], 'Jelinek': [2577], 'Reuter': [2579], 'Shannon': [2581], 'Weber': [2583], 'M.J.': [2584], '271:': [2589], '31562-31571Abstract': [2590], '(95)': [2598], '29.Tice': [2601], 'D.A.': [2602, 2629, 3440], 'Biscardi': [2603, 3441], 'Nickles': [2605, 3443], 'A.L.': [2606, 3444], 'Parsons': [2607, 2634, 3445], 'S.J.': [2608, 2635, 3446], '96:': [2617, 3455], '1415-1420Crossref': [2618, 3456], '(397)': [2621, 3459], '30.Biscardi': [2624], 'Maa': [2626], 'M.C.': [2627], 'Tice': [2628], 'Cox': [2630], 'M.E.': [2631], 'Leu': [2632], 'T.H.': [2633], '8335-8343Abstract': [2641], '(556)': [2649], 'Scholar);': [2651], 'published': [2653], 'cultured': [2657, 3828], 'adherent': [2658], 'cells,': [2659], 'engaged': [2666], 'fibronectin': [2668], 'derived': [2669], 'serum.Figure': [2673], '3C-Src': [2674], '(Col': [2705, 3539], 'IV),': [2706], 'lysates': [2724, 3617], 'testedin': [2726], 'enzyme.': [2735], 'incubation': [2741], '[32P]ATP': [2746], '(upper': [2748], 'panel)': [2749], 'presence': [2753, 2793, 3544, 3851], '(3': [2757], 'units/sample)': [2758], '(lower': [2759], 'panel).32P': [2760], 'incorporation': [2761, 2788], 'detected': [2763], 'SDS-PAGE': [2765], 'autoradiography.': [2767], 'B,': [2768, 2909], 'c-Src-induced': [2769], 'calculated': [2773], 'densitometry': [2775], 'bands': [2780, 3665], 'ratio': [2785], '32P': 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