Publication Information

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'activation': [66, 178], 'site,': [67], 'integrity': [69], 'this': [71, 173], 'loop': [72], 'was': [73, 197], 'maintained': [74], 'in': [75, 136, 227], 'mutants.': [78], 'The': [79, 95], 'amidolytic': [80], 'plasminogen-activating': [82], 'activities': [83, 98], 'mutants': [86, 110, 156, 196, 224], 'averaged': [87], '0.14': [88], '0.12%': [90], 'that': [91, 114, 131, 176, 241], 'TC-UK,': [93], 'respectively.': [94], 'fibrin': [96, 204], 'plate': [97], '2,400': [100], 'IU/ml': [101], '700': [103], 'IU/mg': [104], 'for': [105, 127], 'or': [111, 145, 214, 252], 'about': [112], '1.5%': [113], 'TC-UK.': [116], 'These': [117, 231], 'findings': [118, 232], 'attest': [119], 'discrete': [122], 'but': [123], 'low': [124], 'activity': [126], 'suggest': [130], 'higher': [133, 162], 'values': [134], 'reported': [135], 'literature': [138], 'may': [139], 'be': [140], 'related': [141], 'contaminants': [144], 'plasmin-induced': [146], 'TC-UK': [147, 213], 'generation': [148], 'during': [149], 'assay.': [151], 'Clot': [152, 192], 'lysis': [153, 188, 193, 249], 'required': [157], 'doses': [158], 'greater': [159], 'than': [160, 163, 261], '100-fold': [161], 'induce': [168], 'comparable': [170], 'effect.': [171], 'From': [172], 'it': [174], 'appears': [175], 'is': [179, 254], 'major': [181], 'determinant': [182], 'rate': [185], 'clot': [187, 248], 'occurring': [189], 'with': [190, 237], 'pro-UK.': [191, 238], 'potentiated': [198], 'pretreatment': [201], 'addition': [208], 'small': [210], 'amounts': [211], 'tissue': [215], 'plasminogen': [216], 'activator': [217], '(t-PA).': [218], 'Combinations': [219], 't-PA': [221, 253], 'synergistic': [226], 'their': [228], 'effects.': [230], 'mirror': [233], 'previously': [235, 243], 'obtained': [236], 'We': [239], 'concluded': [240], 'described': [244], 'potentiation': [245], 'pro-UK-induced': [247], 'mediated': [255], 'primarily': [256], 'itself': [259], 'rather': [260], 'promotion': [264], 'activation.': [267]}, 'cited_by_api_url': 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