Title: Physical and biological dosimetry at the barium sulphate–culture medium interface
Abstract: Barium sulphate suspensions (BSS) used in gastrointestinal radiography consist of barium sulphate microparticles which coat the mucosal surface of the digestive tract. The amount of BSS which adheres to the mucosa depends upon the procedure employed, the type of BSS, the amount and dilutions used, and the surface properties of the mucosa (Gelfand & Ott, 1982). These barium microparticles, once taken internally, penetrate deeply into the intestinal mucosa, even into the crypts between villi (Simmonds & James, 1976), forming tissue-barium interfaces. An interface between a solid metal and a tissue when irradiated yields a region of overdosage at the proximal interface and an underdosed region at the distal side (Dutreix & Bernard, 1966). However, suspended barium (atomic number (Z) = 56) microparticles release secondary electrons in all directions when irradiated, resulting in overdosage regions on both sides of the interface. In this communication, we report the measurement of doses at regions proximal and distal to a culture medium–BSS interface by a biological assay (cell survival) method, as a simulation of the dosimetry at the tissue–BSS interface. Physical dosimetry was also carried out to measure the amount of secondary electrons released from BSS and from a mylar membrane.
Publication Year: 1986
Publication Date: 1986-11-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 10
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